Protective mechanism of quercetin compounds against acrylamide-induced hepatotoxicity by Linzi Li, Xueying Lei, Lin Chen, Ya Ma, Jun Luo, Xuebo Liu, Xinglian Xu, Guanghong Zhou, Xianchao Feng

“…In vivo studies found that quercetin-like compounds protect against AA-induced liver injury by reducing oxidative stress levels, activating the Akt/mTOR signaling pathway to attenuate autophagy, and improving mitochondrial apoptosis and endoplasmic reticulum stress-mediated apoptosis. …”
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Determinants of survival of the bovine blastocyst to cryopreservation stress: treatment with colony stimulating factor 2 during the morula-to-blastocyst transition and embryo sex by Froylan Sosa, Jeremy Block, Yao Xiao, Peter J. Hansen

“…Here, we tested whether addition of 10 ng/mL CSF2 at day 5 of development would increase the survival of blastocysts harvested at day 7 and subjected to vitrification. …”
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The Association of Vitamin D, Nerve Growth Factor (NGF), Brain-Derived Neurotrophic Factor (BDNF), and Glial Cell-Derived Neurotrophic Factor (GDNF) with Development in Children by Mia Milanti Dewi, Akhmad Imron, Nelly Amalia Risan, Grace Mediana, Raden Tina Dewi Judistiani, Budi Setiabudiawan

“…The risk factors associated with short stature were vitamin D levels ≤ 32.7 ng/dL, GDNF levels ≤ 12.99 ng/mL, male sex, and low maternal education. Children with short stature (<2 years old) also demonstrated impaired problem-solving as assessed by the ASQ-3 (<i>p</i> = 0.005). …”
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Synergistic mixture of Parthenium hysterophorus L. extract and potassium iodide as a novel efficient composite inhibitor on steel corrosion in sulfuric acid by Hao Wu, Shuduan Deng, Dandan Shao, Gaofei Wei, Juan Xu, Xianghong Li

“…Weight loss tests demonstrated that PHLE moderately inhibited corrosion of cold rolled steel (CRS) in 0.50 M H2SO4, with a maximum efficiency of 74.45%. The inhibition efficiency increased to 91.51% with the addition of a small amount of KI (10 mg L−1). …”
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Preparation of Sea-buckthorn Oil Microcapsule Composite Film and the Preservation Effect of Hand-grabbed Mutton by Bingbing ZHANG, Guishan LIU, Delang XIE, Haiyang MA, Yang LI, Fang MA, Xiaojun LI, Qingqing CAO, Xiaoxue LI, Qian ZHANG

“…Results showed that the embedding rate and yield of sea buckthorns oil microcapsules were 88.94% and 76.28%, respectively, and the optimum conditions for preparing the membrane were 6 g/100 mL gelatin concentration. The ratio of gelatin to glycerin was 1:0.4 and the drying conditions were 20 ℃ for 48 h. …”
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Pharmacological Preconditioning Improves the Viability and Proangiogenic Paracrine Function of Hydrogel-Encapsulated Mesenchymal Stromal Cells by Francesco K. Touani, Melanie Borie, Feryel Azzi, Dominique Trudel, Nicolas Noiseux, Shant Der Sarkissian, Sophie Lerouge

“…Bone marrow MSCs from rat (rMSC) and human (hMSC) origin were preconditioned for 1 hour with celastrol 1 μM or vehicle (DMSO 0.1% v/v), then encapsulated within a chitosan-based thermosensitive hydrogel. …”
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Review of Challenges in Performing Real-World Evidence Studies for Nonprescription Products by Maihöfner C, Mallick-Searle T, Vollert J, Kalita P, Sood Sethi V

“…Ltd, SingaporeCorrespondence: Vidhu Sood Sethi, GSK Consumer Healthcare Singapore Pte Ltd (Co Regn No. 201309040M), 23 Rochester Park &num;03-02, 139234, Singapore, Tel +6596447203, Email vidhu.x.sethi@haleon.comAbstract: In recent years, regulatory authorities have signaled a willingness to consider real-world evidence (RWE) data to support applications for new claims and indications for pharmaceuticals. …”
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Developmental deficits, synapse and dendritic abnormalities in a Clcn4 KO autism mice model: endophenotypic target for ASD by Seong Mi Lee, Yura Choi, Dayeon Kim, Ha Jin Jeong, Young Ho Do, Sohee Jung, Bomee Lee, Hyung Jun Choi, Suhyeon Kim, Jung-Min Oh, Songhee Jeon, Jinju Han, Yeni Kim

“…RNA sequencing data from mouse neural progenitor cells (mNPCs) showed that the genes regulating trans-synaptic signaling, transmembrane transport, and neuronal projection development were significantly decreased in Clcn4 knockdown (KD) cells compared to wild type (WT). …”
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Effect of Different Cooking Methods on Lipid Content and Fatty Acid Profile of Red Mullet ( Mullus barbatus ) by Francesca Biandolino, Ermelinda Prato, Asia Grattagliano, Isabella Parlapiano

“…All cooking methods caused significant changes in the fatty acid (FA) profile of M. barbatus . The content of saturated fatty acids (SFA) varied significantly between raw and cooked fish with the lowest values determined for fried sample. …”
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A dataset of Antarctic ecosystems in ice-free lands: classification, descriptions, and maps by Anikó B. Tóth, Aleks Terauds, Steven L. Chown, Kevin A. Hughes, Peter Convey, Dominic A. Hodgson, Don A. Cowan, John Gibson, Rachel I. Leihy, Nicholas J. Murray, Sharon A. Robinson, Justine D. Shaw, Jonathan S. Stark, Mark I. Stevens, John van den Hoff, Jane Wasley, David A. Keith

“…This produced a spatially explicit hierarchical classification with nine Major Environment Units (Tier 1), 33 Habitat Complexes (Tier 2) and 269 Bioregional Ecosystem Types (Tier 3) mapped at 100 m resolution and aligned with ‘level 4’ of the IUCN Global Ecosystem Typology. …”
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Thrombophilia screening in women with recurrent first trimester miscarriage: is it time to stop testing? – a cohort study and systematic review of the literature by Hassan Shehata, Ranjit Akolekar, Amanda Ali, Mariane Silva-Edge, Shahla Haroon, Abdullatif Elfituri, Radhika Viswanatha, Haider Jan

“…Persistent positive lupus anticoagulant (LA) was found in 0.5% (6/1155) and persistent positive anticardiolipin (ACL) antibodies with a value ≥40 U/mL was found in 0.5% (6/1155) of patients. Tests for LA/ACL were performed a minimum of 12 weeks apart thus meeting the revised Sapporo criteria for a diagnosis of antiphospholipid syndrome.Conclusion The findings of our study demonstrate that the prevalence of inherited thrombophilia is similar in women with RM to that in the general population. …”
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Body mass index, proteinuria and total lymphocyte counts in predicting treatment responses among ART naïve individuals with HIV initiated on antiretroviral treatment in Dar es Sala... by Ellen Hertzmark, Patricia Munseri, Lazaro Jassely, Basil Tumaini

“…Objectives To explore the potential use of body mass index (BMI), proteinuria and total lymphocyte count changes in predicting immunological and virological response in individuals with HIV initiated on antiretroviral treatment (ART).Design Prospective cohort study.Setting Three urban HIV care and treatment centres in Dar es Salaam.Participants Individuals with HIV initiating ART.Outcome measures HIV viral load ≥1000 copies/mL (viral non-suppression) at 6 months after ART initiation.Results Of 215 (out of 220 enrolled) participants who returned for evaluation at 6 months, 147 (66.8%) were women. …”
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Etiology of Ascites and Pleural Effusion Associated with Ovarian Tumors: Literature Review and Case Reports of Three Ovarian Tumors Presenting with Massive Ascites, but without Per... by Ai Miyoshi, Takashi Miyatake, Takeya Hara, Asuka Tanaka, Naoko Komura, Shinnosuke Komiya, Serika Kanao, Masumi Takeda, Mayuko Mimura, Masaaki Nagamatsu, Takeshi Yokoi

“…The amount of ascites was 6,300, 2,600, and 3,600 mL, respectively, and was serous in all. Cytodiagnosis of the ascites found that one was positive for tumor cells and two were negative. …”
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Developing a method for root-zone soil moisture monitoring at the field scale using remote sensing and simulation modeling by Hamideh Noory, Morteza Khoshsima, Atsushi Tsunekawa, Mitsuru Tsubo, Nigussie Haregeweyn, Salar Pashapour

“…The proposed method could improve the spatiotemporal resolution of surface and root-zone SM monitoring via simulation of daily root-zone SM at a spatial resolution of 10 m. This method may enable the development of precise irrigation systems that optimize water allocations and conserve limited water resources at the field scale.…”
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Abdominal fat distribution and its relationship to brain changes: the differential effects of age on cerebellar structure and function: a cross-sectional, exploratory study by Yvonne Böttcher, Michael Stumvoll, Kees Straatman, Matthias Raschpichler, Matthias Leopold Schroeter, Katrin Arelin, Haiko Schlögl, Dominik Fritzsch, Meinhard Mende, André Pampel, Arno Villringer, Karsten Mueller

“…Moreover, we aimed to investigate whether these effects change with age.Design Cross-sectional, exploratory.Setting University Clinic, Integrative Research and Treatment Centre.Participants We included 100 (mean BMI=26.0 kg/m², 42 women) out of 202 volunteers randomly invited by the city's registration office, subdivided into two age groups: young-to-mid-age (n=51, 20–45 years of age, mean BMI=24.9, 24 women) versus old (n=49, 65–70 years of age, mean BMI=27.0, 18 women).Main outcome measures VAT, BMI, subcutaneous abdominal adipose tissue, brain structure (grey matter density), functional brain architecture (eigenvector centrality, EC).Results We discovered a loss of cerebellar structure with increasing VAT in the younger participants, most significantly in regions involved in motor processing. …”
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Dairy Foods in a Moderate Energy Restricted Diet Do Not Enhance Central Fat, Weight, and Intra-Abdominal Adipose Tissue Losses nor Reduce Adipocyte Size or Inflammatory Markers in... by Marta D. Van Loan, Nancy L. Keim, Sean H. Adams, Elaine Souza, Leslie R. Woodhouse, Anthony Thomas, Megan Witbracht, Erik R. Gertz, Brian Piccolo, Andrew A. Bremer, Michael Spurlock

“…No diet differences were observed in weight, fat, or IAAT loss; nor SAT mRNA expression of inflammation, circulating cytokines, fasting lipids, glucose, or insulin. …”
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A Performance Evaluation and Inter-laboratory Comparison of Community Face Coverings Media in the Context of COVID-19 Pandemic by Soleiman Bourrous, Mathieu Barrault, Victor Mocho, Stéphane Poirier, Nathalie Bardin-Monnier, Augustin Charvet, Dominique Thomas, Alexandre Bescond, Axel Fouqueau, Tatiana Mace, François Gaie-Levrel, François-Xavier Ouf

“…This specification imposes a minimal air permeability of 96 L m−2 s−1 for a 100 Pa pressure drop and a minimal filtration efficiency of 70% for 3 µm diameter particles. …”
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LEGAL FRAMEWORK OF ENVIRONMENTAL LAW FOR AGRICULTURAL PRODUCTION IN POLAND by Monika Król

“…Wezwanie do zintegrowania celów w zakresie ochrony środowiska, a zwłaszcza różnorodności biologicznej z działalnością rolniczą widoczne jest w wielu aktach prawnych m.in w prawie emisyjnym, w regulacji odnoszącej się do działalności uciążliwej i niebezpiecznej, czy przepisom dotyczącym ochrony i korzystania z zasobów biosfery. …”
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Interaction effect between vitamin D and gestational diabetes mellitus in the second trimester by MA Ziwen, DING Xiaoying, CHU Liming, ZHANG Yan, ZHANG Aifeng, ZHU Yanjun, WANG Xun, XIE Zhenyu

“…The risk of GDM is significantly reduced when serum 25(OH)D level ≥30 ng∙mL-1.…”
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Therapeutic drug monitoring and neutralizing anti-drug antibody detection to optimize TNF-alpha inhibitor treatment for uveitis by Howard C. Chen, Jenny Shunyakova, Amit K. Reddy, Srujay Pandiri, Lynn Hassman

“…Patients were considered to have neutralizing drug antibodies when serum drug levels were low (less than or equal to 6 mcg/mL) and anti-adalimumab antibodies were present on reflex testing. …”
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