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47381
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47382
Myxedema Psychosis: Neuropsychiatric Manifestations and Rhabdomyolysis Unmasking Hypothyroidism
Published 2020-01-01“…Additional investigations revealed a high thyroid-stimulating hormone (TSH) of 56.6 mIU/L, low free T4<0.5 pmol/L, elevated creatine kinase of 3601 U/L, and urine dipstick positive for blood, suggestive of myoglobinuria. …”
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47383
New insights into the mechanism of triphenyl phosphate and its metabolite diphenyl phosphate in diabetic kidney disease
Published 2025-02-01“…The study also detected mRNA expression of core targets molecularly docked with TPHP and DPHP using real-time-PCR. …”
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47384
High Quality–Factor All–Dielectric Metacavity for Label–Free Biosensing
Published 2025-01-01“…Moreover, the metacavity biosensor achieves high surface sensitivity, together with a detection‐limit of 119 viral copies mL−1 for label‐free severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) pseudovirus sensing, revealing remarkable performance in both bulk and surface sensing.…”
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47385
Feedback loop centered on MAF1 reduces blood–brain barrier damage in sepsis-associated encephalopathy
Published 2025-01-01“…Furthermore, it increased phosphatase and tensin homolog (PTEN) expression and inactivated the serine/threonine kinase (AKT)/mechanistic target of the rapamycin kinase (mTOR) signaling pathway. Interference with forkhead box O1 (FOXO1) inhibited MAF1 expression and activated the RIG-I/IRF3 signaling pathway, while MAF1 overexpression promoted PTEN expression, decreased cell apoptosis, and normalized autophagy. …”
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47386
Lipidomics-based association study reveals genomic signatures of anti-cancer qualities of pigmented rice sprouts
Published 2025-01-01“…This superior MTA combination exhibited potent inhibitory activity against HCT116 and A549 cell lines, with average 1/IC50 values of 0.03 and 0.02 (mL/μg), respectively, compared to the inferior MTAs.DiscussionCollectively, our findings demonstrate that MTAs linked to selected GDSL esterase/lipase (GELP) genes, OsACP1, and lecithin-cholesterol acyltransferase significantly enhance antioxidant and anti-cancer properties, potentially through the mobilization of unsaturated lipids and carotenoids during germination. …”
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47387
Exacerbation of diabetes due to F. Nucleatum LPS-induced SGLT2 overexpression in the renal proximal tubular epithelial cells
Published 2025-01-01“…The renal tissue SGLT2 mRNA amounts and the number of renal proximal tubules with overexpressed SGLT2 in the lumen were more in the Fn-LPS-administered-diabetic mice than in diabetic mice. …”
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47388
Temporal Trends in the Utilization and Survival Outcomes of Lobar, Segmental, and Wedge Resection for Early-Stage NSCLC, 2004 to 2020
Published 2025-03-01“…Methods: To examine the trends over time in the utilization, quality, and overall survival (OS) differences of lobectomy, segmentectomy, and wedge resection, we performed an observational, population-level study of 76,466 patients with T1 or T2 N0M0 NSCLC tumors 2 cm or less in size in the National Cancer Database, from 2004 to 2020. …”
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47389
Concordancia de la clasificación VI-RAD S® y la patología en espécimen de cistectomía en un centro oncológico colombiano
Published 2023-10-01“…Objetivo: El objetivo principal de este estudio es evaluar la concordancia del reporte de la clasificación Vesical Imaging-Reporting and Data System (VI-RADS®) en resonancia magnética (RM) y el reporte de patología del espécimen de cistectomía y definir si este estudio puede considerarse un estándar en el proceso de estadificación en el paciente con diagnóstico clínico de cáncer de vejiga. Método: Estudio analítico retrospectivo de corte transversal, se incluyeron 34 pacientes llevados a cistectomía radical o parcial a quienes se realizó RM multiparamétrica prequirúrgica y se realizó un estudio de concordancia entre la clasificación VI-RADS® y el resultado de patología. …”
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47390
Exploring the relationship between Total Athleticism score and CrossFit® Open Performance in amateur athletes: single measure involving body fat percentage, aerobic capacity, muscl...
Published 2024-08-01“…The athletes presented an average of body fat (8.6 ± 2.0%), maximal oxygen consumption (53.3 ± 2.4 mL. (kg.min)-1), 2km row time (07:00 ± 00:21 mm:ss), 1-Repetition maximum in power clean (125.2 ± 21.2 kg) and Tibana test performance (281.0 ± 35.9 repetitions). …”
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47391
Characterization of Avocado (<i>Persea americana</i> Mill) Seed Extract from the Variety Semil 34 Cultivated in the Dominican Republic
Published 2025-01-01“…The hydroalcoholic extract of the Semil 34 seeds exhibited an antioxidant capacity of 1743.3 ± 52.3 µM Trolox/g extract, total phenolic content of 25.86 ± 2.17 mg gallic acid equivalents/g extract, and total flavonoid content of 2.09 ± 0.10 mg quercetin equivalents/g extract. …”
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47392
Angiopoietin-2 and D-dimer add prognostic information to clinical risk in pulmonary arterial hypertension
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47393
Investigating slope stability of multiple stopes prone to instability in the Ziluoyi iron ore mining site
Published 2025-01-01“…By employing an appropriate rock mass reduction model, its constants (m and s) and RMR score for the consisting layers (schist layer and ore body) of the three understudy slopes (Slope#1–Slope#3) are evaluated. …”
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47394
Influence of light intensity, pre-harvest fasting, and storage time on biochemical components in serum and plasma of broilers
Published 2025-02-01“…At 42 days old, 140 broilers (3,123 ± 654 g) were assigned to two light intensities (5 or 20 lux m−2) and seven fasting times (0, 2, 4, 6, 8, 10, and 12 h). …”
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47395
miR-16-5p aggravates sepsis-associated acute kidney injury by inducing apoptosis
Published 2024-12-01“…In vitro, the expression level of miR-16-5p in HK-2 cells treated with 10 μg/mL lipopolysaccharide (LPS) increased by more than 2 times. …”
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47396
Feasibility and Safety of the Distal Transradial Artery for Coronary Diagnostic or Interventional Catheterization
Published 2020-01-01“…A lower body mass index was a higher risk factor for dTRA access failure (odds ratio = 0.79, P=0.024), with a cutoff of 22.04 kg/m2. Conclusion. Compared to conventional TRA, dTRA had a comparable high success rate, with fewer associated complications. …”
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47398
PNPO‐Mediated Oxidation of DVL3 Promotes Multiple Myeloma Malignancy and Osteoclastogenesis by Activating the Wnt/β‐Catenin Pathway
Published 2025-02-01“…Mechanistically, PNPO oxidizes disheveled 3M282 (DVL3), leading to abnormal activation of the Wnt/β‐catenin pathway. …”
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47399
HLA-DMB correlates with antitumor immunity and an improved prognosis in endometrial carcinoma tumors
Published 2025-01-01“…Finally, the expression of HLA-DMB was validated by qPCR and immunohistochemistry.ResultsThe expression of HLA-DMB at both mRNA and protein levels is significantly higher in UCEC tissues compared to normal tissues. …”
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47400
Characterization of Active Compounds of Different Garlic (Allium sativum L.) Cultivars
Published 2018-03-01“…The lowest IC50 values for DPPH•, ABTS•+ scavenging and Cu2+ chelating ability were determined in Chinese garlic extracts (4.63, 0.43 and 14.90 μg/mL, respectively). Extracts from Spanish cultivar Morado and Chinese garlic were highly cytotoxic to human skin fibroblasts as they reduced cellular proliferation by 70–90%. …”
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