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47341
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47342
The Utility of Synovial Fluid Interleukin-10 in Diagnosing Chronic Periprosthetic Joint Infection: A Prospective Cohort Study
Published 2025-01-01“…At a cut-off of 10.305 pg/mL, SF IL-10 had an area under the ROC curve (AUC) of 0.891, with 92.16% sensitivity and 77.91% specificity. …”
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47343
Low dose DNA methyltransferase inhibitors potentiate PARP inhibitors in homologous recombination repair deficient tumors
Published 2025-01-01“…Results Our targeted variants and cells with intrinsic BRCA1/2 mutations responded to low dose combination therapeutic treatment by G2M stalling, compounded DNA damage, severely attenuated colony formation, and importantly, increased cell death. …”
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47344
Amorphization and siliconization of silicon carbide as a first wall material
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47345
Eğitim Çalışanlarının Yansıtıcı Düşünme Becerilerinin Çeşitli Değişkenler Açısından İncelemesi-Examination Of Reflective Thinking Styles Of Education Emloyees In Terms Of Some Vari...
Published 2015-01-01“…Öngörülü ve içten olma ile mesleğe bakış alt boyutlarının haricindeki tüm alt boyutlarda katılımcıların mesleki kıdemlerine göre anlamlı farklılık bulunmaktadır (p<0,05). …”
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47346
Excitation of ULF, ELF, and VLF Resonator and Waveguide Oscillations in the Earth–Atmosphere–Ionosphere System by Lightning Current Sources Connected with Hunga Tonga Volcano Erupt...
Published 2025-01-01“…The density of effective lightning current in the ULF range reaches the value of the order of 10<sup>−7</sup> A/m<sup>2</sup>. A combined dynamic/quasi-stationary method has been developed to simulate ULF penetration through the lithosphere (Earth)–atmosphere–ionosphere–magnetosphere system. …”
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47347
Metabolite profile and antioxidant activities of Trikatu, black pepper, Javanese long pepper, and red ginger essential oils
Published 2025-02-01“…The antioxidant activities of TR, BP, JLP, and RG essential oils were significantly different, with RG showing the lowest IC50 value 2.73 ± 0.09 mg/mL, indicating higher antioxidant potential compared to BP and JLP. …”
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47348
Comprehensive multi-omics analysis showed that CDC6 is a potential prognostic and immunotherapy biomarker for multiple cancer types including HCC
Published 2025-03-01“…Methods: Explored CDC6 mRNA and protein expression in normal human tissues and tumors using TCGA, GTEx, and HPA. …”
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47349
MRTX1133 attenuates KRASG12D mutated-colorectal cancer progression through activating ferroptosis activity via METTL14/LINC02159/FOXC2 axis
Published 2025-02-01“…LINC02159 expression is regulated by METTL14, with METTL14 knockdown decreasing m6A methylation of LINC02159, leading to its increased expression in CRC cells. …”
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47350
Identification of serum tRNA-derived small RNAs biosignature for diagnosis of tuberculosis
Published 2025-12-01“…Levels of tsRNA-Gly-CCC-2, tsRNA-Gly-GCC-1, and tsRNA-Lys-CTT-2-M2 were significantly elevated in the serum of TB patients compared to non-TB individuals, showing a correlation with lung injury severity and acid-fast bacilli grades in TB patients. …”
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47351
Synergistic evolution of dual-precipitation and reverted austenite on mechanical properties in 2.4 GPa ultrahigh strength steel
Published 2025-01-01“…Furthermore, NiAl not only precipitates uniformly in the matrix of martensite but also facilitates the highly uniform distribution of M2C in the matrix. The growth of reverted austenite at boundaries of martensite reduces the amount of precipitations at the same position. …”
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47352
Successful Treatment of Myeloid Sarcoma in an Elderly Patient with Myelodysplastic Syndrome with Reduced-Dose Azacitidine
Published 2021-01-01“…Monotherapy with reduced-dose AZA (37.5 mg/m2 for 7 days, every 4–6 weeks) was restarted, and the MS quickly disappeared. …”
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47353
Anxiolytic, Antidepressant, and Anticholinesterase Effects of Essential Oil from <i>Myrcia sylvatica</i> (G.Mey.) DC
Published 2025-01-01“…Moreover, MsEO inhibited acetylcholinesterase with an IC<sub>50</sub> of 0.47 μg/mL. These findings suggest that MsEO has potential therapeutic applications for anxiety and depression disorders, with additional anticholinesterase activity warranting further investigation in cognitive-related conditions.…”
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47354
Integrative analysis of immunogenic PANoptosis and experimental validation of cinobufagin-induced activation to enhance glioma immunotherapy
Published 2025-02-01“…Cinobufagin effectively induced PANoptosis, leading to increased immunogenic cell death, facilitated tumor-associated microglia/macrophages (TAMs) polarization towards an M1-like phenotype while augmenting CD4+/CD8 + T cell infiltration and activation. …”
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47355
A consort‐guided randomized, blinded, controlled clinical trial on the effects of 6 weeks training on heart rate variability in thoroughbred horses
Published 2025-01-01“…Results V̇O2max, LF/HF ratio, and LFnu increased while HFnu decreased in the training group (before and after training mean [SD] values: V̇O2max 134 [12.8]‐146 [16.5] mL/[kg min]; P < .001; LF/HF ratio 0.51 [0.2]‐0.91 [0.3] [P = .02]; LFnu 37.5 [10.1]‐46.8 [7.8] [P = .02]; HFnu 76.2 [7.9]‐53.2 [7.7] [P < .001]). …”
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47356
Oral Supplementation with Three Vegetable Oils Differing in Fatty Acid Composition Alleviates High-Fat Diet-Induced Obesity in Mice by Regulating Inflammation and Lipid Metabolism
Published 2023-02-01“…It also decreased leptin, pro-inflammatory cytokines, such as tumor necrosis factor-alpha (TNF-α), interleukin (IL)-6, and (IL)-1beta (IL-1β), and increased anti-inflammatory adipokine adiponectin at both secretion and mRNA expression levels in the epididymal adipose tissue (EAT). …”
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47357
Prefronto-Cerebellar Transcranial Direct Current Stimulation Improves Sleep Quality in Euthymic Bipolar Patients: A Brief Report
Published 2014-01-01“…Methods. 25 euthymic outpatients with a diagnosis of BD Type I or II have been enrolled in the study. tDCS montage was as follows: cathode on the right cerebellar cortex and anode over the left dorsolateral prefrontal cortex (DLPFC); the intensity of stimulation was set at 2 mA and delivered for 20 min/die for 3 consecutive weeks. …”
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47358
Palmitic Acid Methyl Ester Enhances Adipogenic Differentiation in Rat Adipose Tissue-Derived Mesenchymal Stem Cells through a G Protein-Coupled Receptor-Mediated Pathway
Published 2021-01-01“…Moreover, PAME significantly increased phosphorylation of extracellular signal-regulated kinases (ERK), but not AKT and mTOR. Cotreatment with PAME and a GPR40/120 antagonist together inhibited the PAME-enhanced ERK phosphorylation and adipogenic differentiation. …”
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Epigenome-wide association study of Chinese monozygotic twins identifies DNA methylation loci associated with estimated glomerular filtration rate
Published 2025-01-01“…Gene expression profiling sequencing was employed to measure mRNA expression levels, and the GEE model was used to investigate the association between gene expression and eGFR. …”
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Identification of Immune-Related lncRNA Pairs and Construction and Validation of a New Prognostic Signature of Colon Cancer
Published 2022-01-01“…We downloaded the expression matrix of mRNA and lncRNA of patients with colon cancer and their clinical information from the public TCGA database. …”
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