Therapeutic potential of brentuximab vedotin in breast cancer and lymphoma via targeted apoptosis and gene regulation by Abeer Ezzat, Mohga Shafiek, Shimaa Shawki, Shaimaa Abdel-Ghany, Mahmoud Nazih, Hussein Sabit

“…Additionally, cell cycle analysis indicated G2/M phase arrest in cancer cells, particularly in MCF-7 and MDA-MB-231, while HSF cells remained largely unaffected. …”
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Comparative analysis of the chemical composition and size of starch granules in grain between diploid and tetraploid sweetcorn cultivars by E. B. Khatefov, V. I. Khoreva, Yu. A. Kerv, T. V. Shelenga, V. V. Sidorova, Y. N. Demurin, V. G. Goldstein

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Donor Identification, Genetic Diversity, Population Structure and Marker–Trait Association Analyses for Iron Toxicity Tolerance Using Rice Landraces by Debanjana Saha, Udit Nandan Mishra, Chittaranjan Sahoo, Seema Tripathy, Uttam Kumar Behera, Susmita Das, Chandrasekhar Sahu, Shiv Datt, Manoj Kumar Rout, Tanmaya Lalitendu Mohanty, Shakti Prakash Mohanty, Saumya Ranjan Barik, Ishwar Chandra Mohanty, Sharat Kumar Pradhan

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Bioresorbable fibers for interstitial null-separation diffuse optical spectroscopy using fast temporal gating by Vamshi Damagatla, Nadia G Boetti, Laura Di Sieno, Diego Pugliese, Ilaria Bargigia, Davide Janner, Alberto Dalla Mora, Antonio Pifferi

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Retinal Ganglion Cell Atrophy in Homonymous Hemianopia due to Acquired Occipital Lesions Observed Using Cirrus High-Definition-OCT by Tsutomu Yamashita, Atsushi Miki, Katsutoshi Goto, Syunsuke Araki, Go Takizawa, Yoshiaki Ieki, Junichi Kiryu, Akio Tabuchi, Yasuyuki Iguchi, Kazumi Kimura, Yoshiki Yagita

“…The average thicknesses of the GCL+IPL were 64.6 and 82.0 μm on the hemianopic and unaffected sides, respectively, and the measurement was significantly thinner on the former side (p=0.018). …”
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Experimental and modeled analysis of contaminant mobility in coal fly ash landfills under continuous rainfall regimes by Shuyuan Xu, Yongbo Zhang, Jiangbo Guo, Aijing Wu, Xinghua Xiang, Haodong Sun

“…To mitigate this risk, the Guofeng Power Plant may consider utilizing locally compacted Malan loess in combination with geosynthetic materials or implementing a liner much thicker than 1.5 m to enhance the impermeability of the fly ash landfill.…”
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Research on path planning for coal mine rescue robots by ZHU Hongbo, YIN Hongliang

“…In laboratory environments, experimental results show: ① In static environments, the HSTA*-G-DWA algorithm reduces the path search time by 58.75% on average compared to the traditional A* algorithm, and the minimum distance between the robot's edge and obstacles increases by 0.71 m on average. ② In unknown environments, compared to the traditional A* algorithm, the HSTA*-G-DWA algorithm can avoid unknown obstacles in real time, resulting in smoother paths.…”
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MAPK4 inhibits the early aberrant activation of B cells in rheumatoid arthritis by promoting the IRF4-SHIP1 signaling pathway by Pei Huang, Guangli Yang, Pingping Zhang, Yin Zhu, Yaning Guan, Jian Sun, Qian Li, Yang An, Xiaoqi Shi, Juanjuan Zhao, Chaohong Liu, Zhixu He, Yan Chen, Zuochen Du

“…Loss of MAPK4 in KO mice enhances proximal BCR signaling and activates the PI3K-AKT-mTOR pathway, leading to heightened B cell proliferation. …”
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Predominant yeasts in Chinese Dong fermented pork (Nanx Wudl) and their aroma-producing properties in fermented sausage condition by Ruifang Mi, Xi Chen, Suyue Xiong, Biao Qi, Jiapeng Li, Xiaoling Qiao, Wenhua Chen, Chao Qu, Shouwei Wang

“…Among these yeasts, P. membranifaciens, M. farinosa, K. exigua and K. bulderi were detected in fermented meats for the first time. …”
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Synthesis and Evaluation of PCL/Chitosan/CQD‐Fe Magnetic Nanocomposite for Wound Healing: Emphasis on Gene Expression by Elham Maghareh Abed, Fatemeh Yazdian, Abbas Akhavan Sepahi, Behnam Rasekh

“…The MIC of Cs/CQD‐Fe against Staphylococcus aureus and Escherichia coli bacteria was 0.08 and 0.04 µg/mL, respectively. The mean expression of genes TGF‐β and PDGF in the nanocomposite group were 0.05 and 0.015 on day 5 and 0.18 and 0.34 on day 15 and significantly increased after 15 days, whereas the mean expression of MMP1 in the nanocomposite group was 0.63 on day 5 and 0.12 on day 15 and significantly decreased after 15 days. …”
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A Real-Time Human Pose Measurement System for Human-In-The-Loop Dynamic Simulators by Nicola Giulietti, Davide Todesca, Marco Carnevale, Hermes Giberti

“…The method’s accuracy and execution time are assessed using the public Human3.6M dataset, evaluating different model configurations, formats, camera setups, and acquisition modes for real-time applications. …”
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Expression Analysis of Heavy-Chain-Only Antibodies in Cloudy Catshark and Japanese Bullhead Shark by Reo Uemura, Susumu Tanimura, Nao Yamaguchi, Ryuichi Kuroiwa, Gabriel Takashi Andrés Tsutsumi, Toshiaki Fujikawa, Kiyoshi Soyano, Kohsuke Takeda, Yoshimasa Tanaka

“…The obtained antiserum and mAbs recognized the C4 recombinant protein of the cloudy catshark, but reacted minimally with the plasma of non-immunized cloudy catsharks and instead reacted with the plasma of Japanese bullhead sharks. …”
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FLT3 is associated with dendritic cell infiltration, tertiary lymphoid structure construction, and predict response to checkpoint inhibitors immunotherapy in solid cancers by Yongchang Tang, Hong Wang, Jiankun Zhang, Chunhui Yang, Fei Xu, Yan Song, Tianen Li, Qiangbo Zhang

“…We analyzed the frequency of FLT3 alterations, its mRNA expression levels, and its prognostic implications across multiple cancer types. …”
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High‐Performance Pure Water‐Fed Anion Exchange Membrane Water Electrolysis with Patterned Membrane via Mechanical Stress and Hydration‐Mediated Patterning Technique by Yeonjae Lee, Sungjun Kim, Yoseph Shin, Yeram Shin, Seongmin Shin, Sanghyeok Lee, Minseop So, Tae‐Ho Kim, Sehkyu Park, Jang Yong Lee, Segeun Jang

“…The universal applicability of this technique was confirmed using in‐house fabricated anion exchange membranes, achieving exceptional current densities of 13.7 A cm−2 at 2.0 V in 1.0 M potassium hydroxide (KOH) and 2.8 A cm−2 at 2.0 V in pure water at 60 °C. …”
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Ribosomal proteins mediate non-canonical regulation of gut inflammatory signature by crop contaminant deoxynivalenol by Juil Kim, BoGyoung Song, Ki-Hyung Kim, Yuseok Moon

“…Through a combination of transcriptomic analysis and experimental models, we demonstrate that while RPL13A negatively regulates inflammation by enhancing the anti-inflammatory transcription factor ATF3, RPS3 acts as a proinflammatory driver, promoting chemokine production via activation of MAPK pathways, transcriptional upregulation of EGR-1, and stabilization of mRNA through cytosolic translocation of HuR. Our findings reveal a dynamic interplay between RPL13A and RPS3, wherein RPL13A counteracts the proinflammatory effects of RPS3, offering a finely tuned regulatory axis in the inflammatory response to environmental toxins. …”
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Morphofunctional characteristics of leaves and fruits in Maloideae (Rosaceae): a. Microstructure of surface tissues by T. Kh. Kumachova, A. S. Voronkov, A. V. Babosha, A. S. Ryabchenko

“…Species-specific traits were also found in the structure of the surface tissue of the pericarp. M. germanica, unlike the other species, does not have a continuous cuticular cover and wax deposits: most of a mature fruit’s surface is covered with a peeling cork layer. …”
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In silico comparative genomic analysis unravels a new candidate protein arsenal specifically associated with Fusarium oxysporum f. sp. albedinis pathogenesis by Hafida Ayada, Boutayna Dhioui, Hamid Mazouz, Abdelhay El harrak, Fatima Jaiti, Bouchra Ouhmidou, Mohammed Diouri, Mohieddine Moumni

“…Those include effectors encoded by Foa unique genes that are involved in Foa penetration (Egh16-like family), host defense mechanisms suppression (lysM family) and pathogen protection (cysteine-rich protein family). …”
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Identification of a novel immunogenic cell death-related classifier to predict prognosis and optimize precision treatment in hepatocellular carcinoma by Dongjing Zhang, Bingyun Lu, Qianqian Ma, Wen Xu, Qi Zhang, Zhiqi Xiao, Yuanheng Li, Ren Chen, An-jiang Wang

“…In this study, we systematically analyzed the mRNA profiles of ICD-related genes in 1847 HCC patients and identified three molecular subtypes with significantly different immune features and prognostic stratification. …”
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Alteration in the Cytokine Secretion of Bone Marrow Stromal Cells from Patients with Chronic Myelomonocytic Leukemia Contribute to Impaired Hematopoietic Supportive Activity by Hui Shi, Yingshao Wang, Rong Li, Wen Xing, Feng-Chun Yang, Jie Bai, Yuan Zhou

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Environmental DNA-based assessment of multitrophic biodiversity in a typical river located in the Loess Plateau, China: Influence of PAHs and suspended sediments by Qian Li, Yulu Tian, Yongrong Hao, Chengkai Qu, Rungnapa Tagun, Hisato Iwata, Jiahua Guo

“…Fishes (Cypriniformes and Clupeiformes) demonstrated greater tolerance to PAH contamination than algae and metazoans, and their reduced richness and Shannon index were linked to the high SS loads (> 0.45 μm). The co-occurrence patterns highlighted a stronger association connection between algae and metazoan communities than fish. …”
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