Silymarin as a Therapeutic Agent for Hepatocellular Carcinoma: A Multi-Approach Computational Study by Ouided Benslama, Sabrina Lekmine, Hamza Moussa, Hichem Tahraoui, Mohammad Shamsul Ola, Jie Zhang, Abdeltif Amrane

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Zinc Affects Differently Growth, Photosynthesis, Antioxidant Enzyme Activities and Phytochelatin Synthase Expression of Four Marine Diatoms by Thi Le Nhung Nguyen-Deroche, Aurore Caruso, Thi Trung Le, Trang Viet Bui, Benoît Schoefs, Gérard Tremblin, Annick Morant-Manceau

“…Zinc-supplementation (20 μM) effects on growth, photosynthesis, antioxidant enzyme activities (superoxide dismutase, ascorbate peroxidase, catalase), and the expression of phytochelatin synthase gene were investigated in four marine diatoms (Amphora acutiuscula, Nitzschia palea, Amphora coffeaeformis and Entomoneis paludosa). …”
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Arsenic toxicity in Antarctic krill oil and its impact on human intestinal cells by Haiyan Zhang, Yunyun Ji, Zhongquan Jiang, Guangxin Yang, Cong Kong, Zhemin Shen, Tao Yuan, Xiaosheng Shen

“…Arsenic exposure elevated ROS levels, disrupted mitochondrial membrane potential, upregulated apoptosis-related genes such as Caspase-3, Caspase-9, and Bax, and downregulated the PI3K/AKT/mTOR signaling pathway. This study elucidates the mechanisms underlying arsenic toxicity in AKO and underscores its implications for food safety assessments.…”
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Anti‐retinal Autoantibodies in Hydroxychloroquine Eye Toxicity by Samuel D. Good, Grazyna Adamus, Michael B. Gorin, Jordan Jacquez, Jennifer Grossman, Isao Matsuura, Ashira Hasan, Brian Skaggs, Maureen McMahon

“…Results Patients with HCQ retinal toxicity had a higher likelihood of testing positive for anti‐arrestin AAbs (60.7% vs 30.6%, P = 0.001) and anti–pyruvate kinase M2 AAbs (46.4% vs 28.1%, P = 0.05). Patients with HCQ eye toxicity also had a higher number of total anti‐retinal AAbs (mean 3.0 ± 2.40 vs 2.04 ± 1.7, P = 0.01). …”
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Chemical Identification and Antioxidant Screening of Bufei Yishen Formula using an Offline DPPH Ultrahigh-Performance Liquid Chromatography Q-Extractive Orbitrap MS/MS by Jinyan Wu, Bangrong Cai, Ang Zhang, Peng Zhao, Yan Du, Xuefang Liu, Di Zhao, Liu Yang, Xinguang Liu, Jiansheng Li

“…In vitro validation indicated that the free radical scavenging activities of rosmarinic acid and calycosin were similar to that of the positive control (DPPH IC50 = 25.72 ± 1.02 and 147.23 ± 25.12 μg/mL, respectively). Furthermore, calycosin had a high content in serum after the oral administration of BYF, indicating that calycosin might be the major antioxidant compound in BYF.…”
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Fabrication and high temperature electrical conductivity of polymer-derived SiHfBCN ceramic coating by Xichao Dong, Qinghua Zhao, Yao Li, Shaomin Gu, Xinming Xu, Dianwei He, Fang Ye, Laifei Cheng, Xingang Luan, Zhaoju Yu

“…The results indicate that the electrical conductivity of the SiHfBCN ceramic coating pyrolyzed at a lower temperature of 1200 °C reaches an impressive high value of 291.55 S·m−¹ at 1200 °C in argon. Importantly, the results also demonstrate that the coating has remarkable high-temperature conductivity and excellent repeatability and durability. …”
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Registro estratigráfico de la Formación Lisama en la Ruta del Cacao, área de La Fortuna, Barrancabermeja, Colombia by Pablo Emilio Pedraza-Castro, Jairo Hernán Roncancio-Guzmán, Laura Constanza Bocanegra-Rodríguez

“…El levantamiento estratigráfico y análisis de litofacies de la Formación Lisama (1070,9 m), indican que se trata de depósitos de planicie aluvial surcada por ríos trenzados arenosos, ríos meandriformes y canales menores. …”
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COVID-19–sensitive tumour response: 2-year assessment of the SARS-CoV-2 humoral response in cancer patients in oncology hospital in Poland by Piotr Kosiorek, Bożena Mikołuć, Samuel Stróż, Anna Hryniewicz, Dorota E. Kazberuk, Robert Milewski, Anna Grzeszczuk, Magdalena J. Borkowska, Anna Stasiak‐Barmuta

“…Over 2 years, 5,082 SARS-CoV-2 IgG and IgM antibody samples were determined. The concentration of antibodies was assessed in groups of oncological patients: those undergoing anticancer therapy after contracting COVID-19 and those after vaccination against the SARS-CoV-2 infection. …”
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Human health risk from groundwater consumption: A case study in the Apaaso-Tafo Community in the Bono East Region of Ghana by Emmanuel Okyere, Ethel Bentil, Nana Adwoa Kusi-Addai, Lawson Mensah

“…Except for the pH, temperature, turbidity and total coliform bacteria, all parameters met the WHO standards. 40 % of the boreholes contained 50 to 500 cfu/100 mL of coliform bacteria and posed daily infection risks between 1 and 7.63 %. …”
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Olfactory Impairment and Recovery in Zebrafish (<i>Danio rerio</i>) Following Cadmium Exposure by Chiara Maria Motta, Rosa Carotenuto, Chiara Fogliano, Luigi Rosati, Pabitra Denre, Raffaele Panzuto, Rossana Romano, Gianluca Miccoli, Palma Simoniello, Bice Avallone

“…Consequently, this study investigated the impact of short-term exposure (96 h) to 25 µM cadmium chloride on the olfactory system of adult zebrafish. …”
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Differential Immunogenicity and Protective Efficacy Elicited by MTO- and DMT-Adjuvanted CMFO Subunit Vaccines against Mycobacterium tuberculosis Infection by Nadeem Ullah, Ling Hao, Yaqi Wu, Yandi Zhang, Qing Lei, Jo-Lewis Banga Ndzouboukou, Xiaosong Lin, Xionglin Fan

“…Our results demonstrated that the DMT-adjuvanted CMFO could confer more significant protection against M. tuberculosis infection than the CMFO/MTO did in mice. …”
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Association Between Diabetic Control And Anti-Diabetic Medication Adherence Using 8-Point Morisky Medication Adherence Scale In Local Population Of Khyber Pakhtunkhwa by Fuad Ahmad Siddiqi, Bilal Saeed, Mehmood Hussain, Wasif Anwar, Sidra Riaz, Naveed Abbas

“…Most participant in our study sample were educated up to matriculation with BMI <25kg/m2. Average duration of diabetes across the sample was 6.1 ± 3.69 years. …”
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FFAR4 (GPR120) Signaling Is Not Required for Anti-Inflammatory and Insulin-Sensitizing Effects of Omega-3 Fatty Acids by Simone Isling Pærregaard, Marianne Agerholm, Annette Karen Serup, Tao Ma, Bente Kiens, Lise Madsen, Karsten Kristiansen, Benjamin Anderschou Holbech Jensen

“…Moreover, ω3-PUFA fed mice had increased circulating protein levels of the anti-inflammatory adipokine, adiponectin, decreased fasting insulin levels, and decreased mRNA expression of several proinflammatory molecules within visceral adipose tissue. …”
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Burden of Illness in Prostate Cancer Patients with a Low-to-Moderate Risk of Progression: A One-Year, Pan-European Observational Study by Cesare Selli, Anders Bjartell, Javier Burgos, Matthew Somerville, Juan-Manuel Palacios, Laure Benjamin, Libby Black, Ramiro Castro

“…Men (n=672) aged 50–75 years with prostate cancer (Gleason score ≤7, PSA ≤20 ng/mL and clinical staging T1c–T2b) were enrolled in five European countries. …”
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Comparison of Crushed-Zone Skin Factor for Cased and Perforated Wells Calculated with and without including a Tip-Crushed Zone Effect by Ekhwaiter Abobaker, Abadelhalim Elsanoose, Faisal Khan, Mohammad Azizur Rahman, Amer Aborig, Stephen Butt

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A Case of Violent Suicide Attempt in a Context of Myxedema Psychosis following Radioiodine Treatment in a Patient with Graves’ Disease by Louise Todorov, Amel Ait Boudaoud, Rachel Pascal de Raykeer, Alina Radu, Khadija Lahlou-Laforêt, Frédéric Limosin, Cédric Lemogne, Sébastien Czernichow

“…On clinical examination remarkable signs of myxedema were found and blood investigations showed hypothyroidism with an extremely high thyroid stimulating hormone (TSH) level (152 mUI/L; reference range 0.20-5.10). The patient presented delirium symptoms at the time of self-stabbing, which was associated with persecutory delusions and auditory harm command hallucinations. …”
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Risk Factors for Postoperative Nausea and Vomiting After TACE: A Prospective Cohort Study by Yuzhu Wang, Xin Zhou, Guoping Li, Qianzhou Lv, Xiaoyu Li, Zhiping Yan

“…Multiple logistic regression analysis showed that chronic gastritis (odds ratio [OR] = 10.350; <i>p</i> = 0.020), VAS (OR = 3.835; <i>p</i> = 0.003), epirubicin (OR = 26.685; <i>p</i> < 0.001), and the dosage of lipiodol (≥5 mL) (OR = 1.385; <i>p</i> < 0.001) were independent risk factors of PONV after TACE. …”
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Long-term risk factors for developing Barrett’s oesophagus in patients with gastro-oesophageal reflux disease: a longitudinal cohort study by John F Dillon, Paul Brennan, James Cotton, James Carberry, Christopher J Byrne

“…Most were Caucasian (n=1188, 99%), had no formal educational qualifications (n=714; 59.6%) and lived with overweight (mean body mass index &gt;25 kg/m2). Many lived in areas of least socioeconomic resource (n=568; 47.4%). 139 (11.6%) had BO at baseline. …”
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The Impact of Infectious Diseases on Clinical Characteristics and Immunological Correlations in Pediatric Henoch–Schönlein Purpura: A Five-Year Retrospective Study by Sînziana Oprițescu, Gabriela Viorela Nițescu, Mihaela Golumbeanu, Dora Boghițoiu, Elena Iuliana Ioniță, Diana-Andreea Ușurelu, Cristian Lucaci, Adriana Negoiță, Elena Moroșan

“…Measurements of immunological panels (IgA, IgM, IgG, and IgE), C3, C4, C-reactive protein, fibrinogen, and hematite sedimentation rate (VSH) determined using blood samples revealed that there is a strong correlation between the elements of the immunological panel and the HSP manifestations. …”
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Techno-economic analysis of cutting-edge PV systems deployment and reconfigurations on rooftop industrial building in Saudi Arabia’s eastern region by Abdulrhman Klifa Al-Hanoot, Hazlie Mokhlis, Saad Mekhilef, Mohammad Alghoul, Hussain Shareef, Zaid Alotaibi

“…This study conducts an in-depth analysis of the energy performance and economic feasibility of utilizing five cutting-edge PV systems on the rooftop of an industrial building spanning approximately 29,000 m2 in Abqaiq City, Saudi Arabia. The primary focus lies in evaluating the performance of these systems within the local grid’s conditions, with an average monthly electrical consumption of 534,000 kWh/month. …”
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