Berberine Protects against Palmitate-Induced Endothelial Dysfunction: Involvements of Upregulation of AMPK and eNOS and Downregulation of NOX4 by Ming Zhang, Chun-Mei Wang, Jing Li, Zhao-Jie Meng, Sheng-Nan Wei, Ji Li, Richard Bucala, Yu-Lin Li, Li Chen

“…Nitric oxide (NO) level and production of reactive oxygen species (ROS) were determined in supernatants or in the cultured HUVECs. The mRNA level of endothelial nitric oxide synthase (eNOS) was measured by RT-PCR, and the protein levels of eNOS, p-eNOS, Akt, p-Akt, AMPK, p-AMPK, and NADPH oxidase (NOX4) were analyzed. …”
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Technologies of suspension cultivation in bioreactor of the Chlamydophila abortus strain on McCoy cell culture by Yerkin Krykbayev, Nurtas Tyrsynbayev, Nurlan Akhmetsadykov, Damir Khussainov, Zhanat Batanova

“…Isolated pathological material was grown in McCoy cell cultures that were suspended in a bioreactor in Dulbecco’s Modified Eagle’s Medium (DMEM) nutrient medium with 10% foetal bovine serum and antibiotics at a concentration of 2×105 cells/mL. Enzyme immunoassay was a confirmation of the successful result of cultivation. …”
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Three dimensional printed models of the airway for preoperative planning of open Laryngotracheal surgery in children: Surgeon’s perception of utility by Oshri Wasserzug, Gadi Fishman, Narin Carmel-Neiderman, Yael Oestreicher-Kedem, Maher Saada, Solomon Dadia, Eran Golden, Philip Berman, Ophir Handzel, Ari DeRowe

“…Five pediatric airway surgeons evaluated the three-dimensional models for determining the surgical approach, incision location and length, graft length, and need for single or double-stage surgery of seven children (median age 4.4 years, M:F ratio 4:3). They rated the importance of the three-dimensional model findings compared to the direct laryngoscopy videos and CT findings for each domain on a validated Likert scale of 1–5. …”
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Targeted Polymer–Peptide Conjugates for E-Selectin Blockade in Renal Injury by Nenad Milošević, Marie Rütter, Yvonne Ventura, Valeria Feinshtein, Ayelet David

“…Results: We found that the mRNA levels of E-selectin were up-regulated in the kidney following acute and chronic tissue injury. …”
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Cryo-Imaging and Software Platform for Analysis of Molecular MR Imaging of Micrometastases by Mohammed Q. Qutaish, Zhuxian Zhou, David Prabhu, Yiqiao Liu, Mallory R. Busso, Donna Izadnegahdar, Madhusudhana Gargesha, Hong Lu, Zheng-Rong Lu, David L. Wilson

“…Tape transfer method and nonrigid registration allowed accurate (<11 μm error) registration of whole mouse histology to corresponding cryo-images. …”
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Influence of Pretreatments on Microwave Vacuum Drying Kinetics, Physicochemical Properties and Sensory Quality of Apple Slices by Yingqiang Wang, Hongxiao Zhao, Huiwen Deng, Xi Song, Wenjie Zhang, Sirui Wu, Jing Wang

“…As calculated according to the Fick's law of diffusion, the moisture diffusivities ( D eff ) ranged from 1.64×10 -8 to 3.46×10 - 8 m 2 /s. Different pretreatment methods had a significant influence on the physicochemical properties and sensory qualities of the dried products (p<0.05). …”
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Physical development and sociocultural context influences on children’s physical activity by Alessandro Hervaldo Nicolai Ré, Maria Teresa Cattuzzo, David Stodden, Guilherme dos Santos, Albert Lucas Olinto Tertuliano, Carlos Bandeira de Mello Monteiro, Diogo Henrique Constantino Coledam, Anthony David Okely

“…Methods: This is a cross-sectional study with 367 preschoolers (53% girls), assessing CRF (PREFIT 20m shuttle run), MC (battery of motor skills), PA (accelerometry), maternal education and parental perception of children’s preferred leisure (questionnaires). …”
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NIH funding for the pediatric surgeon-scientist: An analysis of current trends by Colton D. Wayne, MD, Zachary Dumbauld, BS, Ethan Mills, BS, Diana L. Farmer, MD, Gail E. Besner, MD

“…There were 371 previous/current grants totaling $387,148,625. 31.7 % of funded surgeons held Chair/Chief positions, 77.9 % were male, and 84.1 % had M.D. degree only. 282 (76.0 %) grants were independent, and 42 (11.3 %) were mentored. 100 (69.0 %) funded surgeons obtained independent investigator awards, 33 (22.8 %) with and 67 (46.2 %) without prior training/mentored grants. …”
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Effects of Functional Oligosaccharides Extracted from Straw on the Growth, Feeding, Physiology, Histology, Muscle Texture, and Gut Microbiota of Micropterus salmoides by Benli Wu, Long Huang, Cangcang Wu, Jing Chen, Xiajun Chen, Xiang Wang, Kai Cui, Zhigang Liu, Jixiang He

“…There were significant differences in muscle texture indices for M. salmoides over the fed additive gradient, and the hardness, gumminess, and chewiness were highest in the 1.0 mg/kg group. …”
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Elevated SAMD3 expression in T cells predicts improved survival in pancreatic ductal adenocarcinoma patients by Lingyi Fu, Enliang Zhou, Shuo Li, Ziteng Li, Liyan Wu, Xinxin Zhou, Lang Tian, Bokang Cui

“…Design We investigated the heterogeneity and gene expression profiles of T cells using a single-cell RNA sequencing (sc-RNA-seq) dataset comprised of human PDAC samples. SAMD3 mRNA expression was further evaluated in a tumor-specific OT-I/ovalbumin (OVA) mouse model. …”
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Liquid–Solid Triboelectric Nanogenerator‐Based DNA Barcode Detection Biosensor for Species Identification by Wenlong Ma, Jiawei Li, Xiaolin Qu, Shao‘e Sun, Yanan Zhou, Yitong Liu, Peng Wang, Zhongli Sha

“…Such biosensor successfully recognizes Alvinocaris muricola among different types of Alvinocarididae shrimps, and its low limit detection can reach 1×10−12 m. The present work provides a paradigm‐shift way to develop an inexpensive and accurate technique to detect DNA barcode for species identification, and paves a novel way for the application of liquid–solid TENG.…”
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In Vitro Evaluation of Leakage at Implant-Abutment Connection of Three Implant Systems Having the Same Prosthetic Interface Using Rhodamine B by Antoine Berberi, Georges Tehini, Khaldoun Rifai, Farah Bou Nasser Eddine, Nabil El Zein, Bassam Badran, Haidar Akl

“…After determination of the inner volume of each implant systems, the kinetic quantification of leakage was evaluated for each group using Rhodamine B (10−2 M). For each group, spectrophotometric analysis was performed to detect leakage with a fluorescence spectrophotometer at 1 h (T0) and 48 h (T1) of incubation time at room temperature. …”
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A novel 4-(1,3,4-thiadiazole-2-ylthio)pyrimidine derivative inhibits cell proliferation by suppressing the MEK/ERK signaling pathway in colorectal cancer by Li Weiwei, Yang Zhifu, Ding Likun, Wang Ying, Zhao Xian, Chu Jian Jie, Ji Qing, Yao Minna, Wang Jingwen

“…Compound 4 also inhibited colony formation, migration, and invasion of HCT116 cells in a dose-dependent manner, as well as inducing cell apoptosis and arresting the cell cycle in the G2/M phase. In addition, compound 4 was able to inhibit the activation of the MEK/ERK signaling in HCT116 cells. …”
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Effects of the interface structure on the mechanical and tribological properties of the MoS2/CuCr composites by Chao Guo, Hongqu Jiang, Yuan Luo, Haijun Wu, Qi Zhao, Xingxia Yang, Caiju Li, Jianhong Yi, Yichun Liu

“…Under the normal load of 20 N, compared with the CuCr composite, the friction coefficient of the composite with 7.5 wt % MoS2 content is 0.281, which is significantly reduced by 37.7 %, and the wear rate is 0.1471( × 10−3 mm3/N.m), which is reduced by 50.9 %. This research content can provide a better theoretical basis for changing the problem of poor wettability between the lubricating phase and the matrix.…”
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The effects of circuit hydraulic weight interval training on body composition and progression of resistance in recreationally exercising pre- and postmenopausal women: an 18-week q... by Małgorzata Socha, Paulina Ćwieląg, Waldemar Andrzejewski

“…A total of 100 women aged between 35 and 69 (mean 51.5 ± 9.61) years with a mean body mass index (BMI) of 27.3 (±5.4 kg/m2) were divided by menopausal status and assigned to the training CHWIT group (25 pre- and 25 postmenopausal women) and the control group (25 pre- and 25 postmenopausal women). …”
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Tetrastigma hemsleyanum as a feed additive: modulating gut microbiota for enhancing nutritional transport and growth performance in Jinhua yellow chickens by Chao Lu, Yun Xiang, Kewei Xu, Fengrui Gao, Shaofeng Zhu, Fangfang Lou, Lu Liu, Xin Peng

“…Herein, a total of 120 male Jinhua yellow chickens (two-mth-old) were randomly divided into into four groups (CON, TH-L, TH-M, and TH-H) for a 56-day feeding trial to explore its effects on growth performance and underlying mechanism. …”
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Emission Characteristics, OFPs, and Mitigation Perspectives of VOCs from Refining Industry in China’s Petrochemical Bases by Gulbanu Hini, Kexin Gao, Yi Zheng, Maimaiti Simayi, Shaodong Xie

“…Whilst, ethylene, cis-2-Butene, n-Pentane, n-Butane, and m/p-Xylene were the top five species with the highest contribution to OFPs, accounting for approximately 78% of total OFPs. …”
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Impulsivity, Sensation Seeking, and Risk-Taking Behaviors among HIV-Positive and HIV-Negative Heroin Dependent Persons by Koosha Paydary, Somayeh Mahin Torabi, SeyedAhmad SeyedAlinaghi, Mehri Noori, Alireza Noroozi, Sara Ameri, Hamed Ekhtiari

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ROS-regulated SUR1-TRPM4 drives persistent activation of NLRP3 inflammasome in microglia after whole-brain radiation by Yuan Chang, Yihua He, Di Wang, Kunxue Zhang, Yuzhen Zhang, Zhentong Li, Shuxin Zeng, Sheng Xiao, Suyue Pan, Kaibin Huang

“…We have previously shown that sulfonylurea receptor 1-transient receptor potential M4 (SUR1-TRPM4) mediates microglial NLRP3-related inflammation following global brain ischemia. …”
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Short-term predictive value of sST2 in patients with STEMI following primary PCI: a prospective observational study by Shan Huang, Lu-Jiao Yu, Guang-Feng Sun, Zi-Xin Zhang

“…Results sST2 ranged from 20.57 to 98.96 ng/mL. High sST2 group had higher MACEs rate compared to low sST2 group (28.8% vs. 8.0%, P = 0.001). sST2 was positively correlated with age (r = 0.181, P = 0.027), SYNTAX score (r = 0.257, P = 0.002), high-sensitive C-reactive protein (hs-CRP) (r = 0.225, P = 0.006), B-type natriuretic peptide (BNP) (r = 0.225, P = 0.006) and negatively with left ventricle ejection fraction (LVEF) (r = -0.197, P = 0.016). …”
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