Invasive and Ultrasound Based Monitoring of the Intracranial Pressure in an Experimental Model of Epidural Hematoma Progressing towards Brain Tamponade on Rabbits by Konstantinos Kasapas, Angela Diamantopoulou, Nicolaos Pentilas, Apostolos Papalois, Emmanuel Douzinas, Gregorios Kouraklis, Michel Slama, Abdullah Sulieman Terkawi, Michael Blaivas, Ashot Ernest Sargsyan, Dimitrios Karakitsos

“…We successively introduced 0.1 mL increments of autologous blood into the SG until the Cushing reaction occurred. …”
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Renin-Angiotensin System Genes Polymorphisms and Essential Hypertension in Burkina Faso, West Africa by Daméhan Tchelougou, Jonas K. Kologo, Simplice D. Karou, Valentin N. Yaméogo, Cyrille Bisseye, Florencia W. Djigma, Djeneba Ouermi, Tegwindé R. Compaoré, Maléki Assih, Virginio Pietra, Patrice Zabsonré, Jacques Simpore

“…The polymorphisms were identified by a classical and a real-time PCR. Results. The AGT 235M/T and AT1R 1166A/C polymorphisms were not associated with the hypertension while the genotype frequencies of the ACE I/D polymorphism between patients and controls (DD: 66.83% and 35.78%, ID: 28.22% and 50.98%, II: 4.95% and 13.24%, resp.) were significantly different (p < 10−4). …”
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Changes in Vitamin D Status in Overweight Middle-Aged Adults with or without Impaired Glucose Metabolism in Two Consecutive Nordic Summers by Petra Lundström, Kenneth Caidahl, Maria J. Eriksson, Tomas Fritz, Anna Krook, Juleen R. Zierath, Anette Rickenlund

“…Methods. 158 participants from Sweden (87 women, 71 men; mean age, 60 ± 5 y; body mass index ≥ 25 kg/m2) and 25[OH]D were measured and evaluated in relation to normal or impaired glucose tolerance, body composition, and dietary habits during summer season. …”
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Lactobacillus gasseri LGV03-derived indole-3-lactic acid ameliorates immune response by activating aryl hydrocarbon receptor by Zikang Zhang, Kangdi Zheng, Zhao Zhang, Longbin Cao, Lizhu Lin, Weimin Sun, Feng Qiu

“…L. gasseri LGV03 showed higher potent activities in ameliorating vinorelbine-induced neutropenia, macrophage and T cells deficiency, and significantly enhanced mRNA expressions of cytokines TNF-α, TNF-β and IFN-α. …”
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Purification, Characterization and Antibacterial Mechanism of Plantaricin 2-1 by Mengyang LI, Xiaoxue CHE, Qingshen SUN

“…The minimum inhibitory concentration (MIC) of P2-1 against two indicator strains was 28.5 μg/mL. Plantaricin P2-1 inhibited and/or eradicate the biofilms of two indicator strains. …”
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The Role of SUMO1 Modification of SOX9 in Cartilage Development Stimulated by Zinc Ions in Mice by Na Xue, Jing Zhao, Jing Yin, Liang Liu, Zhong Yang, Shuchao Zhai, Xiyun Bian, Xiang Gao

“…Our investigation was centered on elucidating the impact of zinc deficiency on cartilage maturation by modulating SUMO1 and UBC9 at both the protein and mRNA levels. We administered a regimen inducing zinc deficiency to gravid mice from E0.5 until euthanasia. …”
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FathomDEM: an improved global terrain map using a hybrid vision transformer model by Peter Uhe, Chris Lucas, Laurence Hawker, Malcolm Brine, Hamish Wilkinson, Anthony Cooper, Alex A Saoulis, James Savage, Christopher Sampson

“…We present here, FathomDEM, a new global 30 m DEM produced using a novel application of a hybrid vision transformer model. …”
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Development and Validation of a New Method for Determination of Pb and Cr in Marine Organisms by Total Reflection X-Ray Fluorescence (TXRF) Spectroscopy by Blanca G. Beltrán, Ibiza Martínez-Serrano, Victor Ramos-Sanchez, David Chávez-Flores, Myrna C. Nevárez-Rodríguez, Emilio A. Suárez-Domínguez

“…Working solutions were prepared in 10 mL of a solution 0.005 mol·L−1 EDTA and 1 mol·L−1 HNO3. …”
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Lipoxin Inhibits Fungal Uptake by Macrophages and Reduces the Severity of Acute Pulmonary Infection Caused by Paracoccidioides brasiliensis by Laura R. R. Ribeiro, Flávio V. Loures, Eliseu F. de Araújo, Cláudia Feriotti, Tânia A. Costa, Carlos Henrique Serezani, Sonia Jancar, Vera L. G. Calich

“…In susceptible mice, MLT treatment led to reduced influx of PMN leukocytes, increased recruitment of monocytes, predominant synthesis of anti-inflammatory cytokines, and augmented expression of 5- and 15-lipoxygenase mRNA, suggesting a prevalent LXA4 activity. In agreement, MTL-treated macrophages showed reduced fungal burdens associated with decreased ingestion of fungal cells. …”
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Stacking and Analysis of Melamine in Milk Products with Acetonitrile-Salt Stacking Technique in Capillary Electrophoresis by Yu Kong, Chong Wei, Zhanwu Hou, Zilong Wang, Jiaqiang Yuan, Jiang Yu, Yongxi Zhao, Yuhai Tang, Meili Gao

“…Real milk samples were deproteinized with acetonitrile at a final concentration of 60% (v/v) and then injected hydrodynamically at 50 mBar for 40.0 s. The optimized buffer contains 80.0 mmol/L pH 2.8 phosphates. …”
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Utilization of edible poultry slaughter residues: A chicken-liver hydrolysate with glucose-lowering ability and upregulating glycogenesis in type II diabetes by Yi-Ling Lin, Yu-Pei Chen, Sheng-Yao Wang, Yi-Feng Kao, Chompunut Lumsangkul, Yi-Chen Chen

“…Insulin resistance was induced in liver (FL83B) and muscle (C2C12) cells using 30 and 20 ng TNF-α/mL, respectively, resulting in decreased glucose uptake and lower expressions of IRβ, p-Akt/Akt, and p-GSK3/GSK. …”
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Management of eight cases of subarachnoid hemorrhage using transpulmonary thermodilution during clazosentan therapy by Hiroto Iyota, Yasumasa Kawano, Hironori Fukumoto, Takato Tajiri, Mitsutoshi Iwaasa, Sinichi Morimoto, Yoshito Izutani, Shintaro Yamasaki, Kazuya Yamauchi, Hiroki Hatomoto, Hiroshi Abe, Yoshihiko Nakamura

“…During clazosentan treatment, the median global end-diastolic volume index based on transpulmonary thermodilution remained at 715.5 ml/m2 (interquartile range: 643–788). No ischemic neurological deficits, bilateral pulmonary edema, and pleural effusion were observed. …”
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Performance Improvements of Selective Emitters by Laser Openings on Large-Area Multicrystalline Si Solar Cells by Sheng-Shih Wang, Jyh-Jier Ho, Jia-Jhe Liou, Jia-Show Ho, Wei-Chih Hsu, Wen-Haw Lu, Song-Yeu Tsai, Hsien-Seng Hung, Kang L. Wang

“…In addition, this optimal SE3 cell displays improved characteristics compared with other cells with a higher average value of external quantum efficiency (EQEavg = 68.6%) and a lower average value of power loss (Ploss = 2.33 mW/cm2). For the fabrication of solar cells, the laser opening process comprises fewer steps than traditional photolithography does. …”
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Seasonal resource selection of a grassland bird in a dynamic landscape: Importance of a heterogeneous landscape by Sprih Harsh, Robert C. Lonsinger, Hilary R. Kauth, Andrew J. Gregory

“…We quantified landscape features within radii of 250, 500, and 1000 m (i.e., local to broader spatial scales) from the home‐range center. …”
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Inhibiting the alternative pathway of complement by reducing systemic complement factor B: Randomized, double-blind, placebo-controlled phase 1 studies with Sefaxersen by Michael L. McCaleb, Steven G. Hughes, Tamar R. Grossman, Ashley Frazer-Abel, Bill Jung, Lixuan Yin, Scott P. Henry, Brett P. Monia, Eugene Schneider, Richard Geary, Gary T. Brice

“…In first-in-human double-blind, placebo-controlled phase 1 studies, the safety and pharmacodynamic effects of sefaxersen (RO7434656), a GalNAc-conjugated 2’-MOE antisense oligonucleotide targeting the complement factor B mRNA, was investigated. Healthy volunteers received either single or repeated (for 6 weeks) subcutaneous administrations of investigational drug or placebo. …”
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Extraction of Saponins from Xanthoceras sorbifolium Bunge Leaves Using Deep Eutectic Solvents and Their Inhibitory Activity against Postharvest Pathogenic Fungi by Xue LI, Xinyu CHU, Erzheng SU, Jiahong WANG

“…Results showed that under the conditions of DES concentration of 47.00%, liquid-solid ratio of 42.00 mL/g, and extraction temperature of 43.00 ℃, the yield of XLs saponin using DES reached 10.22%±0.28%, representing a 38.8% increase compared to traditional solvents. …”
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Deciphering In Vitro and In Vivo Pharmacological Properties of Seed and Fruit Extracts of Flacourtia jangomas (Lour.) Raeusch by Farhana Alam Ripa, Fowzia Alam, Fahmida Haque Riya, Yesmin Begum, Sharmin Akter Eti, Nusratun Nahar, Zebunnesa Ahmed, Sabrina Sharmin

“…In the protein denaturation antiarthritic test, the PFJE and SFJC extracts exhibited significant potency, achieving results of 74.28 ± 1.16% and 79.25 ± 0.83%, respectively, at a dose of 500 μg/mL. All samples displayed notable anthelmintic activity by reducing Pheretima posthuma paralysis and death time in a dose-dependent manner compared to albendazole. …”
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Performance evaluation of nine reference centers and comparison of DNA extraction protocols for effective surveillance of Leishmania-infected Phlebotomine sand flies: Basis for tec... by Jorian Prudhomme, Aymeric Delabarre, Bulent Alten, Umut Berberoglu, Eduardo Berriatua, Gioia Bongiorno, José Manuel Cristovao, Maya Davidovich-Cohen, Trentina Di Muccio, Ozge Erisoz Kasap, Eleonora Fiorentino, Oscar D Kirstein, Edwin Kniha, Carla Maia, Mesut Mungan, Clara Muñoz-Hernández, Muhammed Nalçaci, Gizem Oguz Kaskan, Yusuf Ozbel, Seray Ozensoy Toz, Ricardo Parreira, Katharina Platzgummer, Ceylan Polat, José Risueño, Liora Studentsky, Gamze Varol, Julia Walochnik, Kardelen Yetişmiş, Florence Robert-Gangneux

“…<h4>Methodology/principal findings</h4>EQA samples consisted of Leishmania infantum and L. major species, at concentrations ranging from 101 to 104 parasites/mL. All but one center detected all concentrations, demonstrating strong diagnostic proficiency. …”
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Hsa-miR-105-1 Regulates Cisplatin-Resistance in Ovarian Carcinoma Cells by Targeting ANXA9 by Xinxin Kou, Hui Ding, Lei Li, Hongtu Chao

“…Treatment with an Hsa-miR-105-1 inhibitor promoted the expression of ANXA9 mRNA and protein, enhanced the resistance to cisplatin, and attenuated the cell apoptosis induced by cisplatin in cisplatin-sensitive OC cells. …”
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A Comparative Study of Machine Learning Techniques for Predicting Mechanical Properties of Fused Deposition Modelling (FDM)-Based 3D-Printed Wood/PLA Biocomposite by Prashant Anerao, Atul Kulkarni, Yashwant Munde, Namrate Kharate

“…A layer thickness of 0.3 mm and an infill density of 100% yielded the highest tensile strength of 42.46 MPa, flexural strength of 83.43 MPa, and impact strength of 44.76 J/m. The dataset has been carefully prepared to facilitate machine learning for both training and testing, and it contains the experimental results and associated process parameters. …”
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