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45401
High Expression of Polo-Like Kinase 1 Is Associated with Early Development of Hepatocellular Carcinoma
Published 2014-01-01“…We found that PLK1 inhibition promoted cell arrest in G2/M phase of cell cycle and cell apoptosis. Our results also indicated that the potential mechanisms of PLK1 inhibition regulating cell growth involved enhancing expression of caspase3, caspase8, and Bax and decreasing expression of Bcl-2. …”
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45402
A Nonsynonymous Single-nucleotide Polymorphism in SLC24A5 Regulates Feather Pigment Deposition in Chinese Yellow Quail
Published 2025-02-01“…Mutant individuals had significantly lower total melanin content in the feathers and tyrosinase activity in dorsal skin, in spite of no significant difference in SLC24A5 mRNA expression in the same tissues. This study indicates that the g.8884145A/G mutation reduced tyrosinase activity by affecting the function of the SLC24A5 protein, which in turn decreased melanin content of down feathers in Chinese yellow quail.…”
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45403
CD226 Deficiency Alleviates Murine Allergic Rhinitis by Suppressing Group 2 Innate Lymphoid Cell Responses
Published 2022-01-01“…Hematoxylin and eosin and periodic acid–Schiff staining and quantitative real-time PCR methods were used to determine eosinophils, goblet cells, and ILC2-associated mRNA levels in the nasal tissues of mice. CD226 levels on ILC2s were detected using flow cytometry, and an immunofluorescence double staining assay was employed to determine the number of ILC2s in the nasal mucosa. …”
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45404
Design and Development of a Wayside AI‐Assisted Vision System for Online Train Wheel Inspection
Published 2025-01-01“…Different algorithms are evaluated using COCO evaluation metrics, and the best‐performing model, YOLOv9, achieves a mAP50 of 0.94 and a recall of 0.91. The developed system has produced satisfactory results in acquiring proper wheel tread images and segmenting the wheel. …”
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45405
Laparoscopic Gastric Sleeve and Micronutrients Supplementation: Our Experience
Published 2012-01-01“…In the period between July 2008 and April 2010, 138 obese patients (110 females and 28 males) with mean BMI 44.4 kg/m2 ± 6.5, mean age 43.9±10.9 years were enrolled and underwent LGS. …”
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45406
De alfa a omega: Estimación de la confiabilidad ordinal. Una guía práctica
Published 2022-12-01“…Al emplear una muestra de 266 adultos entre 18 y 63 años (M = 31.91, DE = 11.50), se administró la versión adaptada a argentina del Inventario de Ansiedad de Beck y el Cuestionario de Regulación Emocional. …”
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45407
Synbiotics effects of d-tagatose and Lactobacillus rhamnosus GG on the inflammation and oxidative stress reaction of Gallus gallus based on the genus of cecal bacteria and their me...
Published 2025-01-01“…<h4>Results and conclusion</h4>The results indicated that oxidative stress and immune response factor expressions quantity in Gallus gallus decreased significantly after 14 days of treatment, compared with model group, the low-dose treatment group's SOD1, SOD3, GPX1, GPX2, GSR, H6DP, and HO-1 genes in liver were downregulated by 36.03%, 40.01%, 45.86%, 40.79%, 37.68%, 25.04%, and 29.89%, the IL-1, IL-2, IL-4, IL-6, IgA, IgM, and IgG genes in blood and spleen were downregulated by 26.59%, 34.19%, 21.19%, 28.18%, 35.93%, 12.67%, 21.81 and 35.93%, 22.85%, 21.19%, 28.78%, 35.93%, 15.36%, 29.73%. …”
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45408
Wind Field Characteristics of the 13 June 2014 Downburst Event in Beijing Based on Meteorological Tower Records
Published 2024-12-01“…Based on measured data from the 325 m meteorological tower in Beijing, this paper investigates the spatiotemporal evolution of mean and fluctuating winds during a non-stationary downburst. …”
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45409
Understanding the Spatial Heterogeneity of CO2 and CH4 Fluxes from an Urban Shallow Lake: Correlations with Environmental Factors
Published 2017-01-01“…The fluxes in heavy pollution sites with high concentrations of nitrogen and phosphorus nutrient in summer were 3.9 times (142.14 : 36.07 mg·m−2·h−1) for CO2 and 22.3 times for CH4 (6.46 : 0.29) higher than those in little pollution sites. …”
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45410
Accurate Modeling of GaN HEMTs Oriented to Analysis of Kink Effects in S<sub>22</sub> and h<sub>21</sub>: An Effective Machine Learning Approach
Published 2024-01-01“…The device under test (DUT) is a 0.25-<inline-formula> <tex-math notation="LaTeX">$\mu \text{m}$ </tex-math></inline-formula> gallium nitride (GaN) high electron mobility transistor (HEMT) on silicon carbide (SiC) substrate, which has a large gate periphery of 1.5 mm. …”
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45411
Assessing the effects of targeted soccer exercises on the physical fitness of 15-16-year-old schoolchildren
Published 2024-06-01“…There were also statistically significant changes in the level of endurance: in the "running around the perimeter of a 15 x 15 m square" test (t=2.08, p<0.05) and when performing the "Burpee" test (t=2.45, p<0.01). …”
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45412
Coral Reef Degradation Due to ‘Ship Grounding' in Indonesia: Case Study of Ship Aground in Bangka-Belitung Waters by Mother Vessel MV Lyric Poet
Published 2020-09-01“…Corals are damaged with a total area of 13.540m2; equivalent to twice that of an international football field. …”
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45413
The Parenteral Vitamin C Improves Sepsis and Sepsis-Induced Multiple Organ Dysfunction Syndrome via Preventing Cellular Immunosuppression
Published 2017-01-01“…The negative immunoregulation of Tregs was inhibited, mainly including inhibiting the expression of forkhead helix transcription factor- (Foxp-) 3, cytotoxic T lymphocyte associated antigen- (CTLA-) 4, membrane associated transforming growth factor-β (TGF-βm+), and the secretion of inhibitory cytokines [including TGF-β and interleukin- (IL-) 10], as well as CD4+ T cells-mediated cellular immunosuppression which was improved by parenteral Vit C in WT and Gulo−/− septic mice. …”
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45414
Aplicación del análisis factorial para discriminar espacialmente variables geograficas
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45415
Validation of a multiplexed immunoassay for immunological analysis of pre erythrocytic malaria vaccines
Published 2025-01-01“…Abstract The primary immunological readout for clinical trials of R21/MatrixM™ malaria vaccine, is total IgG antibody specific to the central four amino acid NANP repeat region of the circumsporozoite protein. …”
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45416
Experimental Comparison of HfO<sub>2/X</sub>-Based ReRAM Devices Switching Properties by the MIM Capacitance
Published 2024-01-01“…An increase in the capacitance from 3.904 to 3.917 pF/<inline-formula> <tex-math notation="LaTeX">$\mu $ </tex-math></inline-formula>m2 was observed for the same device when it was subjected to a <inline-formula> <tex-math notation="LaTeX">$144~\mu $ </tex-math></inline-formula>s pulse width, demonstrating a conductance quantization required for the application in in-memory computing systems. …”
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45417
Validation of Housekeeping Genes to Study Human Gingival Stem Cells and Their In Vitro Osteogenic Differentiation Using Real-Time RT-qPCR
Published 2016-01-01“…This study demonstrated that three HKGs, SDHA, ACTB, and B2M, were the most stable to study GSC, whereas TBP, SDHA, and ALAS1 were the most reliable to study dGSCs. …”
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45418
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45419
Small-Sized Parabolic Trough Collector System for Solar Dehumidification Application: Design, Development, and Potential Assessment
Published 2018-01-01“…Quetta revealed peak solar insolation of 656 W/m2 and peak thermal energy 1139 MJ with 46% efficiency. …”
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45420