Sphingosine-1-Phosphate/Sphingosine-1-Phosphate Receptor 2 Axis Can Promote Mouse and Human Primary Mast Cell Angiogenic Potential through Upregulation of Vascular Endothelial Grow... by Alena Chumanevich, Piper Wedman, Carole A. Oskeritzian

“…Further, we show that S1P stimulation triggered transcriptional upregulation of VEGF-A and MMP-2 mRNA in human but not in mouse MC. S1P exposure also triggered MMP-2 secretion from human MC. …”
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Efficient Feature Selection and Hyperparameter Tuning for Improved Speech Signal-Based Parkinson’s Disease Diagnosis via Machine Learning Techniques by Deepak Painuli, Suyash Bhardwaj, Utku Kose

“…To enhance model performance, the GridSearchCV method was employed for hyperparameter tuning, alongside recursive feature elimination (RFE) and minimum redundancy maximum relevance (mRMR) feature selection techniques. Among the 12 ML models evaluated, the RF model with the RFE-generated feature subset (RFE-50) emerged as the top performer. …”
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Huntington’s disease modeling on HEK293 cell line by D. V. Sharipova, T. B. Malankhanova, A. A. Malakhova

“…We showed that mutant cells partially reproduce the pathological phenotype, that is, they have reduced proliferation activity, an increased level of apoptosis and high sensitivity to treatment with 5μM MG132 proteasome inhibitor compared to the original HEK293 Phoenix cell line. …”
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Psychometric properties of the Persian version of Self-Injurious Thoughts and Behaviors Questionnaire-Nonsuicidal (SITBQ-NS) in an Iranian outpatient sample by Sara Sobhani, Banafsheh Gharraee, Mojgan Salavati, Komeil Zahedi Tajrishi, Hojjatollah Farahani, Alessandra D'Agostino

“…To address this gap, the present study examined the psychometric properties of the Persian version of the SITBQ-NS using data from 350 outpatients (age range: 18–60 years, M = 27.65, SD = 6.61; 20 % male) recruited from two psychiatric hospitals and two university counseling and psychological services centers in Tehran, Iran. …”
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Repeatability and High-Speed Validation of Supplemental Lead-Extrusion Energy Dissipation Devices by Geoffrey W. Rodgers, J. Geoffrey Chase, John B. Mander

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The effect of COVID-19 lockdown on the air environment in India by N. Gupta, A. Tomar, V. Kumar

“…It has been observed that with the above adopted measures temperature has been reduced to near about 15 degree Celsius, there is also reduction in humidity i.e. it is reduced to 40%,  particulate matter (PM2.5)  reaches near about normal i.e. 40 g/m³ and carbon monoxide levels has also been  reduced to 10 ppm. …”
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Up-and-down determination of prophylactic norepinephrine boluses combined with crystalloid co-load for preventing post-spinal anesthesia hypotension during cesarean section by Chengfei Xu, Peipei Zhang, Chunying Dai, Jingjun Zhang, Honghao Wu, Qianying Liu, Zhiqiang Zhang, Fengwei Yin, Huadong Ni, Liang Cheng

“…Methods Patients were administered crystalloid co-loads at a dosage of 10 mL/kg, in addition to preventive norepinephrine dosages direct following spinal anesthesia administration. …”
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Histomorphometrical Study on Regional Variation in Distribution of Sweat Glands in Buffalo Skin by Debajit Debbarma, Varinder Uppal, Neelam Bansal, Anuradha Gupta

“…The paraffin sections of 5-6 μm were cut with rotary microtome and stained with hematoxylin and eosin. …”
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Physicochemical and Sensory Properties of Wine Produced from Blended Cactus Pear (Opuntia ficus-indica) and Lantana camara (L. camara) Fruits by Zenebe Tadesse Tsegay, Kidu Mezgebe Gebremedhin

“…The final wine was characterized as having pH of 3.47 ± 0.04, 4.6 ± 0.02 g/L sugar equivalent to dextrose, 0.33 ± 0.006% titratable acidity (w/v citric acid), total phenol of 696.1 ± 22.1 mg/L equivalent to gallic acid, and 4.35 ± 0.4 mg/mL organic acid equivalent to citric acid composition. …”
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Colada morada, a traditional Ecuadorian Day of the dead beverage: Bibliometric analysis and review of the biological activity of native Ecuadorian ingredients by Juan Carlos Romero-Benavides, Rodrigo Duarte-Casar, Marlene Rojas-Le-Fort, Natalia Bailon-Moscoso

“…Additionally, the antimicrobial and insect-repellent properties of A. citrodora and M. quixos, as well as the antioxidant potential of A. hybridus, underscore their functional relevance. …”
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Exploring the protective role of caffeine against Taraxacum-Induced ribotoxic stress mediated through autophagy and mitochondrial depolarization by Chien-Jung Lin, Shu-Ting Liu, Zih-Syuan Wu, Shih-Ming Huang, Teng-Wei Chen

“…However, caffeine failed to rescue T. formosanum-targeted mRNAs when the RIN values were relatively lower. …”
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Everolimus Implicated in Case of Severe Gastrointestinal Hemorrhage by Paul Gonzales, Seth Klusewitz, Johanna Marowske, John Gancayco, Michael B. Osswald, Robert Setlik

“…With treatment advancements, including targeted agents such as Everolimus, a mammalian target of rapamycin (mTOR) inhibitor, survivability and quality of life continue to improve. …”
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Upregulated Solute Carrier SLC39A1 Promotes Gastric Cancer Proliferation and Indicates Unfavorable Prognosis by Dan Yu, Yong Chen, Ming Luo, Yanjin Peng, Shengen Yi

“…Compared with adjacent stomach tissues, gastric adenocarcinoma tissues showed significantly higher SLC39A1 on both mRNA and protein levels. Higher SLC39A1 was observed in patients with larger tumor size (P=0.003) and advanced tumor stages (P<0.001). …”
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Prevalence, Awareness, Treatment, and Control of Hypertension among Chinese First-Generation Migrants and Italians in Prato, Italy: The CHIP Study by Pietro A. Modesti, Maria Calabrese, Ilaria Marzotti, Hushao Bing, Danilo Malandrino, Maria Boddi, Sergio Castellani, Dong Zhao

“…In Chinese participants, where the optimum cut-off point for body mass index was ≥23.9 kg/m2, the sensibility and specificity prediction for hypertension were 61.7% and 59.8%, respectively (area under the ROC curve = 0.629). …”
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Utilizing the subtractive proteomics approach to design ensemble vaccine against Candida lusitaniae for immune response stimulation; a bioinformatics study. by Habiba Naz, Rimsha Timotheous, Muhammad Farhan Sarwar, Tariq Nadeem, Mudassar Fareed Awan, Sajed Ali, Sophia Awais, Irfan Ahmed

“…Upon final results, it was found that highest count of IgG and IgM was achieved i.e., up to 700000 between the days 8 to 13 and then slowly neutralized till the day 30. …”
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Sociodemographic and Lifestyle Factors in relation to Overweight Defined by BMI and “Normal-Weight Obesity” by Bodil Ohlsson, Jonas Manjer

“…The aim of the present study was to explore the associations between sociodemographic factors and smoking and alcohol habits and lower versus higher BMI (≥25 kg/m2) and to examine whether categorization into lean, NWO, and overweight leads to further information about sociodemographic and lifestyle associations, compared with the common categorization defined by BMI. …”
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Successful Treatment of Rhabdomyolysis-Associated Acute Kidney Injury with Haemoadsorption and Continuous Renal Replacement Therapy by Wun Fung Hui, Kam Lun Hon, Kin Shing Lun, Karen Ka Yan Leung, Wing Lum Cheung, Alexander K. C. Leung

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How Fast Is Recovery of Impaired Glucose Tolerance after 21-Day Bed Rest (NUC Study) in Healthy Adults? by Martina Heer, Natalie Baecker, Stephan Wnendt, Annelie Fischer, Gianni Biolo, Petra Frings-Meuthen

“…Glucose tolerance of seven male, healthy, untrained test subjects (age: 27.6 (3.3) years (mean (SD)); body mass: 78.6 (6.4) kg; height: 1.81 (0.04) m; VO2 max: 39.5 (5.4) ml/kg body mass/min) was studied. …”
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Proceso de atención de enfermería aplicado en paciente adulto mayor con diabetes mellitus tipo 2 by Natividad Sánchez Ahuanari, Carmen Elizabeth Colan Ortiz, Valeria Nathaly Estela y Macedo, Rene Cabanilla Malca, José Gregorio Molina Torres

“…Caso clínico: Paciente O. CH. M., adulto mayor, de 62 años de edad, de sexo femenino, con antecedente de hipertensión arterial y osteoporosis. …”
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Self-selected vs. prescribed aerobic exercise intensity: impacts on pleasure in women with obesity by Carlos Eduardo Rosa Da Silva, Wilian Jesus Santana, Gustavo Almeida, Adriano Verame, Antonio Roberto Doro, Eduardo Barbosa, Leonardo Lima, Helton Magalhães Dias, Marcelo Callegari Zanetti, Aylton Figueira Junior

“…The aim of the present study was to compare the effect of three aerobic training protocols on psychophysiological responses in physically inactive adult obese women.MethodsThe sample consisted of 90 women with a mean age of 48.3 ± 5.5 years and BMI of 31.2 ± 4.8 kg/m2, who participated in three treadmill aerobic training protocols: 1- Control group (IPI) with individually prescribed intensity (64 to 76% of HRmax), 2- Small group (SGS) with self-selected intensity, and 3- Individual with self-selected intensity (ISS). …”
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