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44361
Anti-Inflammatory and Neuroprotective Role of Natural Product Securinine in Activated Glial Cells: Implications for Parkinson’s Disease
Published 2017-01-01“…Additionally, securinine also inhibited interferon-γ- (IFN-γ-) induced nitric oxide levels and iNOS mRNA expression. Furthermore, conditioned media (CM) from securinine pretreated BV2 cells significantly reduced mesencephalic dopaminergic neurotoxicity compared with CM from LPS stimulated microglia. …”
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44362
Improvement of modeling on the Pidgeon process for magnesium production by introducing the variable thermophysical properties
Published 2022-01-01“…The slag layer with lower thermal conductivity of 0.4 W.m-1.K-1 formed during reduction strongly hinders the reaction to move forward within the layers, resulting in the slow magnesium production rate in the Pidgeon process. …”
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44363
Subjective Evaluation of Music Compressed with the ACER Codec Compared to AAC, MP3, and Uncompressed PCM
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44364
Yeni Ahitteki Tyanalı Apollonius -Apollonius of Tyana in New Testament
Published 2015-06-01“…Apollonius, İsa’nın doğduğu varsayılan yılda (M.Ö. 4) aynı gizemli tarz içinde gerçekten doğmuştur. …”
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44365
Cutting-Caving Ratio Optimization of Fully Mechanized Caving Mining with Large Mining Height of Extremely Thick Coal Seam
Published 2019-01-01“…Engineering application showed that the optimal cutting height of Xiegou Coal Mine was 4 m, the cutting-caving ratio was 1 : 2.75, and the recovery rate could reach more than 85%, which was the most reasonable.…”
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44366
Antimalarial Activity of Piperine
Published 2018-01-01“…The median IC50 (concentration that inhibits parasite growth by 50%) values of piperine against 3D7 and K1 P. falciparum were 111.5 and 59 μM, respectively. A marked change in parasite morphology was observed within 48 hours of piperine exposure. …”
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44367
Gastrointestinal Bleeding in Antithrombotic Therapy in Patients with Coronary Heart Disease: Risk Factors, Pathogenesis and Treatment
Published 2020-07-01“…Risk factors of GIB during antithrombotic therapy in CHD patients include: GIB, gastric and/or duodenal ulcer in the history, reflux esophagitis, presence of H. pylori, inflammatory bowel disease, diverticula, haemorrhoids, angiodysplasia, gastrointestinal neoplasia, age above 65 years, concomitant treatment with non-steroidal anti-inflammatory drugs (NSAIDs), glomerular filtration rate <50 mL/min, high doses of direct oral anticoagulants (DOACs) ≥3 in HAS-BLED score. …”
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Strong immune responses and robust protection following a novel protein in adjuvant tuberculosis vaccine candidate
Published 2025-01-01“…Recently, the protein-adjuvated subunit vaccine. M72/AS01E, demonstrated 49.7% efficacy in preventing active TB in latently infected adults, indicating that protective immunity through subunit vaccines is possible. …”
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44370
A straightforward Py-GC/MS methodology for quantification of microplastics in tap water
Published 2025-06-01“…Unlike conventional approaches relying on expensive pyrolyzate libraries, this method identifies pyrolysis fragments by matching their m/z values with commercially available mass spectral libraries (Wiley Registry 12th Edition/NIST 2020) and confirms findings using pure polymer standards. …”
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44372
Supplementation with Branched-Chain Amino Acids Induces Unexpected Deleterious Effects on Astrocyte Survival and Intracellular Metabolism with or without Hyperammonemia: A Prelimin...
Published 2021-01-01“…Furthermore, BCAA treatment was found to cause decreased levels of Glut-1 and phosphorylated GSK-3β and mTOR in astrocytes. Conclusions. Although further investigations of the effect of BCAA on human astrocytes with hyperammonemia are needed, our work demonstrates that BCAA supplementation has direct negative effects on astrocyte survival and intracellular metabolism.…”
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44373
Determination of β-Cyano-L-alanine, γ-Glutamyl-β-cyano-L-alanine, and Common Free Amino Acids in Vicia sativa (Fabaceae) Seeds by Reversed-Phase High-Performance Liquid Chromatogra...
Published 2014-01-01“…The limit of detection and quantification was 0.15 and 0.50 μM, respectively. The method has high intra- (RSD = 0.28–0.31%) and interrepeatability (RSD = 2.76–3.08%) and remarkable accuracy with a 99% recovery in spiked samples. …”
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44374
Verification of CENDL-3.2 Nuclear Data on VENUS-3 Shielding Benchmark by ARES Transport Code
Published 2021-01-01“…Different cross-section parameters are chosen for ARES to calculate VENUS-3 benchmark, and equivalent neutron flux of 58Ni(n,p)58Co, 115In(n,n′)115mIn and 27Al(n,α)24Na detectors is calculated according to the data provided by the benchmark report. …”
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44375
Structure and mechanism of biosynthesis of Streptococcus mutans cell wall polysaccharide
Published 2025-01-01“…The predominant Glc modification, α-Glc, attached to position 2 of 3-rhamnose, is installed by SccN and SccM glycosyltransferases and is the site of the GroP addition. …”
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44376
Social innovations to increase health coverage: evidence from a crowdsourcing contest in Ghana
Published 2022-06-01“…These submissions can be put into three main themes: technology and strengthening (eg, mHealth for cervical cancer screening, video directly observed therapy), inclusiveness and reaching the marginalised (people with disability and infertility) and data utilisation for project improvement (seasonal calendar to reduce morbidity and mortality of children under 5 for malaria, diarrhoea and pneumonia).Conclusion In conclusion, this study shows that solutions to local problems exist. …”
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44377
Synthesis of ultrafine (Mo,W)Si2 composite powders from high purity molybdenum concentrate
Published 2023-01-01“…(Mo,W)Si2 composite powders with the grain size of about 1 μm were synthesized at 1150℃ for 2 h. The high purity molybdenum concentrate (with the main component of MoS2), W and Si powders were utilized as raw materials and lime as desulfurizer. …”
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44378
Niveles auditivos de una cohorte de estudiantes de odontología expuestos a ruido ambiental durante la formación práctica
Published 2018-01-01“…O: Determinar los niveles de audición de una cohorte de estudiantes de odontología expuestos a ruido ambiental durante la formación práctica, comparados con estudiantes de fonoaudiologia, seguidos en el año 2015. M: Se realizó en una cohorte de estudiantes de odontología y estudiantes de otro programa, se evaluaron 63 de odontología y 125 del otro programa. …”
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44379
EVALUATION OF SUITABILITY FACILITIES FOR ACTIVE FIRE PROTECTION IN PT DOK DAN PERKAPALAN SURABAYA (PERSERO)
Published 2020-03-01“…Per 04/MEN/1980 for fire extinguisher, Permen PU No. 26/PRT/M/2008 and SNI 03-1745-2000 for hydrant. Method: This research was observational descriptive one. …”
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44380
‘Vychegodsky’: a new potato cultivar for the Republic of Komi
Published 2021-07-01“…The planting scheme was 70 × 30 cm, at a depth of 8–10 cm, over the experimental plot area of 52.5 m2 (250 tubers), with four replications.Results. …”
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