Differential Gene Expression in Primary Breast Tumors Associated with Lymph Node Metastasis by Rachel E. Ellsworth, Lori A. Field, Brad Love, Jennifer L. Kane, Jeffrey A. Hooke, Craig D. Shriver

“…Lymph node status remains one of the most useful prognostic indicators in breast cancer; however, current methods to assess nodal status disrupt the lymphatic system and may lead to secondary complications. …”
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Lymphatic vessel network injury reduces local tumor control despite preservation of the tumor-draining lymph node by Lauren N. Liebman, Yang Shen, Zachary S. Buchwald, Zhanna Nepiyushchikh, Zhiming Qi, Andrés J. García, J. Brandon Dixon

“…Abstract The lymphatic system plays complex, often contradictory, roles in many cancers, including melanoma; these roles include contributions to tumor cell metastasis and immunosuppression in the tumor microenvironment as well as generation of antitumor immunity. …”
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Real-world pharmacovigilance analysis unveils the toxicity profile of amivantamab targeting EGFR exon 20 insertion mutations in non-small cell lung cancer by Jing Zhang, Wenjie Li

“…Results A significant proportion of adverse events (AEs) was attributable to injury, poisoning, and procedural complications, cutaneous disorders, respiratory ailments, infections, as well as vascular and lymphatic system disturbances. There were noteworthy incidences of AEs including infusion-related reactions, rash, dyspnea, pneumonitis, paronychia, pulmonary embolism, thrombocytopenia, nausea, acneiform dermatitis, deep vein thrombosis, febrile neutropenia, peripheral edema, hypokalemia, and neutropenia. …”
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Comfortable knowing little about lymphoedema? A qualitative study of medical interns in Australia by Samantha Bunzli, Sandra Hayes, Peter Window, Melanie Plinsinga, Natalie Kruger

“…This qualitative study explored the thoughts and feelings of Australian interns (medical graduates in their first postgraduate year) towards (i) their understanding of the lymphatic system and lymphoedema, (ii) curricula pertaining to lymphoedema within their Australian medical degree and (iii) how they perceive that their understanding and medical training in lymphoedema influence their clinical practice.Study design and methods Qualitative semistructured interviews were conducted with interns employed within their first postgraduate year in Australia. …”
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Intensive Treatment of Cellulite Based on Physiopathological Principles by José Maria Pereira de Godoy, Mayra Yara Groggia, Lucilene Ferro Laks, Maria de Fátima Guerreiro de Godoy

“…This technique involving lymphatic system stimulation is efficacious in the treatment of cellulite.…”
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Cystic Lymphangioma of the Greater Omentum: A Case of Partial Spontaneous Regression and Review of the Literature by Haraesh Maranna, Lovenish Bains, Pawan Lal, Rahul Bhatia, Mohd Yasir Beg, Pritesh Kumar, Varuna Mallya

“…Omental cysts are a part of cystic lymphangiomas and are benign proliferations of ectopic lymphatics without a communication with the normal lymphatic system. They commonly involve the neck in the pediatric population and are uncommon at other sites and occur rarely in adults. …”
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MicroRNAs secreted by the parasitic nematode Brugia malayi disrupt lymphatic endothelial cell integrity. by Hailey Johnson, Stephanie Banakis, Matthew Chung, Elodie Ghedin, Denis Voronin

“…The adult parasites impact the integrity of lymphatic vessels and damage valves, leading to a remodeling of the lymphatic system and lymphatic dilation. Chronic infections can develop into severe clinical manifestations, primarily lymphedema, hydrocoele, and elephantiasis. …”
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Comparative and Developmental Anatomy of Cardiac Lymphatics by A. Ratajska, G. Gula, A. Flaht-Zabost, E. Czarnowska, B. Ciszek, E. Jankowska-Steifer, J. Niderla-Bielinska, D. Radomska-Lesniewska

“…The role of the cardiac lymphatic system has been recently appreciated since lymphatic disturbances take part in various heart pathologies. …”
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Protective role of Pannexin1 in lymphatic endothelial cells in the progression of atherosclerosis in female mice. by Avigail Ehrlich, Graziano Pelli, Bernard Foglia, Filippo Molica, Brenda R Kwak

“…Atherosclerosis is a progressive arterial disease arising from imbalanced lipid metabolism and a maladaptive immune response. The lymphatic system ensures tissue fluid homeostasis, absorption of dietary fats and trafficking of immune cells to draining lymph nodes, thereby potentially affecting atherogenesis. …”
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New perspectives on the glymphatic system and the relationship between glymphatic system and neurodegenerative diseases by Yan-rui Sun, Qian-Kun Lv, Jun-Yi Liu, Fen Wang, Chun-Feng Liu

“…The glymphatic system, through its rapid exchange mechanisms between cerebrospinal fluid (CSF) and interstitial fluid (ISF), facilitates the movement of metabolic substances within the brain, serving functions akin to those of the peripheral lymphatic system. This emerging waste clearance mechanism offers a novel perspective on the removal of pathological substances in ND. …”
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Analysis of ADR reports of cetuximab based on the FDA adverse event reporting system database by Shuai Zhao, Yan Wang, Xiaoli Deng, Xi Chen, Zhaoyi Lu

“…The main SOCs (Skin and subcutaneous tissue disorders, investigations, metabolism and nutrition disorders, and blood and lymphatic system disorders) accounted for 58.63%. Some AEs were not on the drug label: speech disorder, intervertebral discitis, glomerulonephritis rapidly progressive and disseminated intravascular coagulation. …”
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Functional effects of operations for malignant gastric neoplasms: prevention, diagnosis and treatment of post-gastrectomy disorders by A. V. Chaika, V. M. Khomyakov, A. B. Ryabov

“…Surgical treatment of gastric cancer includes complete or partial resection of the organ, its lymphatic system and ligaments that is followed by impairment and reduction of digestive process and is associated to series of disorders, related to altered visceral innervation. …”
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Pancreatic Cancer: Molecular, Biochemical, Chemopreventive, and Therapeutic Aspects by Juan Iovanna, José Luis Neira

“…Its lethal nature stems from its propensity to disseminate rapidly to the lymphatic system and distant organs. Yet, understanding and stopping metastasis may prove to be one of the great potential strategies of treating PC. …”
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Abdominal lymphatic malformations in children: case series by Carmine Noviello, Alfonso Papparella, Mirko Bertozzi, Giovanna Riccipetitoni, Ilaria Cascone, Carmine Botta, Giulia Fusi, Veronica Vitali, Mercedes Romano

“… Lymphatic Malformations (LMs) are benign congenital malformations of the lymphatic system that commonly involve the abdomen in children (mesentery of the small intestine and omentum). …”
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A post-marketing pharmacovigilance study of triazole antifungals: adverse event data mining and analysis based on the FDA adverse event reporting system database by Yalan Tian, Min Jin, Hong Ning

“…Voriconazole ADEs primarily involved the following SOCs: Investigations (9.45%), Eye Disorders (8.46%), and Nervous System Disorders (7.21%); Posaconazole ADEs primarily involved the following SOCs: Investigations (13.84%), General Disorders and Administration Site Conditions (11.95%), and Nervous System Disorders (6.29%); Isavuconazole ADEs primarily involved the following SOCs: General Disorders and Administration Site Conditions (15.22%), Hepatobiliary Disorders (10.87%), and Blood and Lymphatic System Disorders (10.87%).ConclusionVoriconazole, posaconazole, and isavuconazole all potentially pose safety risks related to hepatobiliary disorders and cardiac disorders. …”
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Breaking boundaries: role of the brain barriers in metastatic process by Nasim Izadi, Peter Solár, Klaudia Hašanová, Alemeh Zamani, Maryam Shahidian Akbar, Klára Mrázová, Martin Bartošík, Tomáš Kazda, Roman Hrstka, Marek Joukal

“…The metastatic cascade is a multistep process involving local invasion, intravasation into the bloodstream or lymphatic system, extravasation into normal tissue, and colonization of the distal site. …”
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Associated adverse outcomes with tumor treating fields when combined to temozolomide versus temozolomide alone for the treatment of glioblastoma: a meta-analysis of randomized tria... by Yuanyuan Chen, Yan Chen, Hong Zhen, Danhua Lou

“…Results of this analysis showed that TTF in combination with temozolomide was not associated with significantly higher adverse outcomes related to blood and lymphatic system disorders (RR:0.87, 95% CI 0.30–2.48; P = 0.79), gastrointestinal disorders (RR: 0.83, 95% CI 0.14–4.72; P = 0.83), general deterioration and malaise (RR: 1.43, 95% CI 0.90–2.25; P = 0.13), infections and infestations (RR: 1.21, 95% CI 0.33–4.45; P = 0.78), injury/poison and procedural complications (RR: 1.78, 95% CI 0.88–3.61; P = 0.11), metabolic and nutritional disorders (RR: 0.61, 95% CI 0.34–1.08; P = 0.09), central nervous system disorders (RR: 1.14, 95% CI 0.89–1.46; P = 0.31), musculoskeletal and connective tissue disorders (RR: 0.99, 95% CI 0.48–2.07; P = 0.99), respiratory/thoracic/mediastinal disorders (RR: 0.85, 95% CI 0.44–1.62; P = 0.62), and psychiatric disorders (RR: 1.27, 95% CI 0.42–3.79; P = 0.67). …”
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Safety profiles of IDH inhibitors: a pharmacovigilance analysis of the FDA Adverse Event Reporting System (FAERS) database by Ximu Sun, Han Zhou, Yanming Li, Yanhui Luo, Qixiang Guo, Yixin Sun, Chenguang Jia, Bin Wang, Maoquan Qin, Peng Guo

“…The most signals reported were “blood and lymphatic system disorders,” “infections and infestations,” and “nervous system disorders” in enasidenib. …”
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Klippel-Trénaunay Syndrome with Intracranial Arteriovenous Malformation: A Rare Presentation by Mahniya F. Sadiq, Waqas Shuaib, Muhammad H. Tiwana, Jamlik-Omari Johnson, Faisal Khosa

“…Vascular malformations associated with KTS tend to affect slow flow systems: venous, capillary, and lymphatic systems. The nature of the syndrome leads to a higher risk for the development of arteriovenous malformations. …”
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