Palliative endoscopic treatment of malignant central airway obstruction by Mads Bøgh, Sebastian Heinonen, Dalia Gustaityté Larsen, Søren Gade, Sten Schytte, Ulrik Pedersen, Thomas Kjaergaard

“…The majority of patients were categorised with stage IV lung cancer, the majority being males, with a median age of 67 years. …”
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Characterization of Somatostatin Receptor Subtype 2 Expression in Stably Transfected A-427 Human Cancer Cells by Jesse J. Parry, Martin Eiblmaier, Rebecca Andrews, Laura A. Meyer, Ryuji Higashikubo, Carolyn J. Anderson, Buck E. Rogers

“…The human non–small cell lung cancer line A-427 was stably transfected with a hemagglutinin-tagged human sst2. …”
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Emerging PPARγ-Independent Role of PPARγ Ligands in Lung Diseases by Ajit A. Kulkarni, Collynn F. Woeller, Thomas H. Thatcher, Sesquile Ramon, Richard P. Phipps, Patricia J. Sime

“…PPARγ ligands show great promise in moderating lung inflammation, as antiproliferative agents in combination to enhance standard chemotherapy in lung cancer and as treatments for pulmonary fibrosis, a progressive fatal disease with no effective therapy. …”
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Fragile Histidine Triad (FHIT) Suppresses Proliferation and Promotes Apoptosis in Cholangiocarcinoma Cells by Blocking PI3K-Akt Pathway by Qiang Huang, Zhen Liu, Fang Xie, Chenhai Liu, Feng Shao, Cheng-lin Zhu, Sanyuan Hu

“…Phosphatidylinositol 3-OH kinase (PI3K)-Akt-survivin is an important signaling pathway that was regulated by FHIT in lung cancer cells. To determine whether FHIT can regulate this pathway in cholangiocarcinoma QBC939 cells, we constructed an FHIT expression plasmid and used it to transfect QBC939 cells. …”
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Acidovorax temperans skews neutrophil maturation and polarizes Th17 cells to promote lung adenocarcinoma development by Joshua K. Stone, Natalia von Muhlinen, Chenran Zhang, Ana I. Robles, Amy L. Flis, Eleazar Vega-Valle, Akihiko Miyanaga, Masaru Matsumoto, K. Leigh Greathouse, Tomer Cooks, Giorgio Trinchieri, Curtis C. Harris

“…We previously characterized the lung cancer microbiome in patients and identified Acidovorax temperans as enriched in tumors. …”
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Global scenario of silica-associated diseases: A review on emerging pathophysiology of silicosis and potential therapeutic regimes by Prasad Sherekar, Sanvidhan G. Suke, Archana Dhok, Srikant Malegaonkar, Shrikrishna A. Dhale

“…Other crystalline silica-induced pulmonary disorders include a predisposition to mycobacterial infections, obstructive airway diseases, idiopathic pulmonary fibrosis, and lung cancer. This review paper discusses the burden of silicosis and associated co-morbidities in developed as well as developing countries globally using the published data of various government agencies, related organizations, and epidemiological findings. …”
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Progress of CCL20-CCR6 in the airways: a promising new therapeutic target by Ya -Jing Li, Wan-Li Geng, Chen-Chen Li, Jia-Hao Wu, Fei Gao, Yong Wang

“…Within the respiratory system, CCL20-CCR6 demonstrates heightened expression in conditions such as allergic asthma, chronic airway inflammation, non-small cell lung cancer (NSCLC), chronic obstructive pulmonary disease (COPD), and other respiratory diseases, which is conducive to the inflammatory mediators recruitment and tumor microenvironment remodeling. …”
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Exploration of the shared diagnostic genes and molecular mechanism between obesity and atherosclerosis via bioinformatic analysis by Wenrong An, Kegong Tang, Juan Liu, Wenfei Zheng, Guoxia Li, Yunsheng Xu

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Selective inhibition of TGF-β-induced epithelial-mesenchymal transition overcomes chemotherapy resistance in high-risk lung squamous cell carcinoma by Liangdong Sun, Jue Wang, Huansha Yu, Xinsheng Zhu, Jing Zhang, Junjie Hu, Yilv Yan, Xun Zhang, Yuming Zhu, Gening Jiang, Ming Ding, Peng Zhang, Lele Zhang

“…Abstract Lung squamous cell carcinoma (LUSC) represents a major subtype of lung cancer, and it demonstrates limited treatment options and worse survival. …”
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Evaluation of Six Patients with Pulmonary Carcinosarcoma with a Literature Review by Sinem Nedime Sökücü, Celalettin Kocatürk, Nur Ürer, Yaşar Sönmezoğlu, Levent Dalar, Levent Karasulu, Sedat Altın, Mehmet Ali Bedirhan

“…From a retrospective analysis of 1076 non-small-cell lung cancer resections performed between January 1996 and January 2011, six patients (0.5%) with pulmonary carcinosarcoma (all males; mean age 58 years; range 53–66) who underwent surgical treatment were studied. …”
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Absolute quantification of Neuron-specific enolase based on surface plasmon resonance by Cui Lin, Yijie Wang, Tao Peng, Pengpeng Liu, Yuanyuan Liang, Wencheng Kang, Xiaoping Yu, Yang Song, Xuping Shentu

“…Neuron-specific enolase (NSE) is currently the most reliable biomarker for small cell lung cancer (SCLC), which is important for disease monitoring, clinical evaluation and diagnosis. …”
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Indoor and Outdoor Exposure to PM2.5 during COVID-19 Lockdown in Suburban Malaysia by Eliani Ezani, Peter Brimblecombe, Zulfa Hanan Asha’ari, Amirul Aiman Fazil, Sharifah Norkhadijah Syed Ismail, Zamzam Tuah Ahmad Ramly, Md Firoz Khan

“…The estimated excess risk to health was about 25% for lung cancer from staying indoor. Thus, there seems a potential for greater exposure to fine particles indoors under lockdown, so it is likely premature to suggest that more lives were saved through a reduction of outdoor pollutants than lost in the pandemic. …”
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Information needs for cancer screening and associated factors of information-seeking behaviour: a qualitative systematic review by Mingyao Zhou, Yuqing Wu, Dan Wang, Fang Cheng

“…Regarding cancer-specific information needs content, we summarised the specific information needs of cervical, breast, colorectal, and lung cancer. By referring to relevant concepts in the Comprehensive Model of Information Seeking, we synthesised the requirements and preferences for information according to the themes of editorial tone, communication potential, recommended information channels, and recommended source place. …”
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Detection of other pathologies when utilising computer-assisted digital solutions for TB screening by J. Sebastian, I.D. Olaru, A. Giannakis, M. Arentz, S.V. Kik, M. Ruhwald, S. Linsen, G. Günther, P. Wolf, F.J. Herth, T. Weber, C.M. Denkinger

“…The CAD generally detected abnormalities in patients with critical diagnoses such as lung cancer or heart failure. Performance for detecting other abnormalities was variable. …”
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Identification of GPD1L as a Potential Prognosis Biomarker and Associated with Immune Infiltrates in Lung Adenocarcinoma by Zhengyang Fan, Song Wu, Hongyang Sang, Qianping Li, Shaofei Cheng, Hongling Zhu

“…Lung adenocarcinoma (LUAD) is one of the most prevalent pathological kinds of lung cancer, which is a common form of cancer that has a high death rate. …”
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Tumor mutation burden for predicting immune checkpoint blockade response: the more, the better by Ming Zheng

“…Only in cancer types with higher TMB (category I), such as melanoma, colorectal cancer, bladder cancer, and non-small cell lung cancer, the associations between TMB-H and ICB treatment outcomes were less affected by TMB cut-off selection. …”
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Occupational disparities in survival in Korean women with cancer: a nationwide registry linkage study by Ichiro Kawachi, Hye-Eun Lee, Eun-A KIM, Masayoshi Zaitsu

“…HRs for mortality adjusting for age and year of diagnosis were calculated in the study sample and subgroups with 10 specific cancer sites including thyroid, breast, stomach, cervix, colon or lung cancer using managers, professionals and technical workers as the reference.Results Women in service/sales (HR 1.25, 95% CI 1.15 to 1.35) and blue-collar occupations (HR 1.34, 95% CI 1.25 to 1.44) had poorer survival for all cancer sites combined, while blue-collar workers showed poorer survival for lung (HR 1.41, 95% CI 1.14 to 1.77), breast (HR 1.28, 95% CI 1.06 to 1.54), cervical cancer (HR 1.42, 95% CI 1.02 to 2.06) and non-Hodgkin’s lymphoma (HR 1.69, 95% CI 1.09 to 2.77) compared with women in professional and managerial positions.Conclusion We found substantial and significant inequalities in overall survival by the occupational group among Korean women with cancer, even in the context of universal access to cancer screening and treatment.…”
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The development of an efficient artificial intelligence-based classification approach for colorectal cancer response to radiochemotherapy: deep learning vs. machine learning by Fatemeh Bahrambanan, Meysam Alizamir, Kayhan Moradveisi, Salim Heddam, Sungwon Kim, Seunghyun Kim, Meysam Soleimani, Saeid Afshar, Amir Taherkhani

“…Therefore, early detection of colorectal cancer as the second deadliest cancer after lung cancer, can be highly beneficial. Moreover, the standard treatment for locally advanced colorectal cancer, which is widely accepted around the world, is chemoradiotherapy. …”
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Subtype-specific human endogenous retrovirus K102 envelope protein is a novel serum immunosuppressive biomarker of cancer by Qinyuan Gong, Qinyuan Gong, Rongzhen Xu, Rongzhen Xu

“…In contrast, K102-Env markedly increased in patients with PDAC, hepatocellular carcinoma (HCC), and non-small cell lung cancer (NSCLC) compared with healthy controls. …”
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Frequency of Missing TNM Stage Data for Adults With Intellectual or Developmental Disabilities in a Provincial Cancer Registry—A Brief Report by Kelly Biggs, Helene Ouellette‐Kuntz, Rebecca Griffiths, Rebecca Hansford, Julie Hallet, Christine Kelly, Kathleen Decker, David E. Dawe, Shahin Shooshtari, Marni Brownell, Donna Turner, Virginie Cobigo, Alyson Mahar

“…Results Adults with IDD diagnosed with breast, colorectal, and lung cancer were 1.94 (95% CI 1.52–2.47), 1.90 (95% CI 1.63–2.21), and 2.17 (95% CI 1.86–2.54) times more likely to have unknown cancer stage at diagnosis, relative to those without IDD. …”
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