Integrating Knowledge Graphs with Symbolic AI: The Path to Interpretable Hybrid AI Systems in Medicine by Maria-Esther Vidal, Yashrajsinh Chudasama, Hao Huang, Disha Purohit, Maria Torrente

“…This position paper examines the challenges and research opportunities in integrating KGs with neuro-symbolic AI, highlighting their potential to enhance explainability, scalability, and context-aware reasoning in hybrid AI systems. Using a lung cancer use case, we illustrate how hybrid approaches address tasks such as link prediction—uncovering hidden relationships in medical data—and counterfactual reasoning—analyzing alternative scenarios to understand causal factors. …”
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Significantly Delayed Development of Polyarthritis with Active Tenosynovitis after Possible Temporary Neutropenic Immune-Related Adverse Events Caused by Atezolizumab Treatment: A... by Yoshitaka Saito, Yoh Takekuma, Hajime Asahina, Ryo Hisada, Mitsuru Sugawara

“…Here, we report a case of significantly delayed rheumatic irAEs (Rh-irAEs) with prior possible temporary neutropenic irAEs in a patient with atezolizumab-treated non-small-cell lung cancer and its management. A man in his sixties received atezolizumab monotherapy as the sixth-line treatment. …”
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Triple-drug antibiotic therapy for disseminated nocardial abscess in the mediastinum and brain of an immunocompetent patient: a case report by Yue Zhang, Zhongchun Qi, Hua Li, Hui Gao

“…Conclusions Mediastinal nocardiosis with disseminated brain abscesses is a rare condition that can be difficult to differentiate from brain metastases caused by lung cancer. Bacterial culture results, imaging features, and MDT discussions are crucial for accurate diagnosis and treatment. …”
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Asbestos Induces Reduction of Tumor Immunity by Naoko Kumagai-Takei, Megumi Maeda, Ying Chen, Hidenori Matsuzaki, Suni Lee, Yasumitsu Nishimura, Junichi Hiratsuka, Takemi Otsuki

“…Asbestos-related cancers such as malignant mesothelioma and lung cancer are an important issue in the world. There are many conflicts concerning economical considerations and medical evidence for these cancers and much confusion regarding details of the pathological mechanisms of asbestos-induced cancers. …”
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The Use of Porous Scaffold as a Tumor Model by Mei Zhang, Philip Boughton, Barbara Rose, C. Soon Lee, Angela M. Hong

“…High-density low-volume seeding was used to promote attachment of a non-small-cell lung cancer cell line (NCI-H460) to scaffolds. Growth patterns in 3D culture were compared with those of monolayers. …”
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One pot two-step borylation/fluorination reaction of dysobinin from Chisocheton macrophyllus and its cytotoxicity against cancer cell by Muhammad Badrul Huda, Nurlelasari, Wahyu Safriansyah, Mohamad Fajar, Iis Intan Widiyowati, Unang Supratman, Yessi Permana, Yudha P. Budiman

“…-fluorodysobinin showed significantly higher cytotoxicity against A549 lung cancer cells when compared to dysobinin.…”
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Canine lung carcinoma—A descriptive review by Aleksandra Marcinowska, Aleksandra Marcinowska, Rodrigo Dos Santos Horta, Felisbina Queiroga, Felisbina Queiroga, Antonio Giuliano, Antonio Giuliano, Antonio Giuliano

“…Primary lung cancer is a relatively uncommon tumor in dogs, accounting for about 1% of all canine malignancies. …”
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Image Characterization of Cancer of the Colon by Thaimi Conde Cueto, Martha Yudey Rodríguez Pino, Pedro Juan Barrios Fuentes, Bárbara Aleida García Hernández, Julio Suz Piña, Nery M. Díaz Yanes

“…<strong>Background:</strong> Cancer of the colon is the second cause of death due to cancer worldwide, alter lung cancer in males and breast cancer in females. It is not possible to confirm the patient’s diagnosis without the result of image tests such as barium enema, ultrasound cytology or biopsy of the lesion. …”
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Feasibility of Using High-Resolution Computed Tomography Features for Invasiveness Differentiation of Malignant Nodules Manifesting as Ground-Glass Nodules by Xinyue Chen, Benbo Yao, Juan Li, Chunxiao Liang, Rui Qi, Jianqun Yu

“…Ground-glass nodule (GGN)-like adenocarcinoma is a special subtype of lung cancer. The invasiveness of the nodule correlates well with the patient’s prognosis. …”
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Receptor Status Differences in Prognosis for Breast Cancer by Yelda Deligöz Bildacı, Deniz Yamaç, Uğur Coşkun

“…It is the most common cancer type in the world after lung cancer. The prognosis of the disease mostly depends on the type and stage of cancer. …”
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p53 dosage can impede KrasG12D- and KrasQ61R-mediated tumorigenesis. by Özgün Le Roux, Jeffery I Everitt, Christopher M Counter

“…Loss of the Trp53 gene encoding the tumor suppressor p53 enhances the ability of oncogenic Kras to initiate tumorigenesis in carcinogen and genetic models of lung cancer. Conversley, an extra copy of Trp53 (Super p53) was recently shown to suppress Kras-induced tumorigenesis in a genetic model of this disease. …”
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Implications of the Incidental Finding of a MYCN Amplified Adrenal Tumor: A Case Report and Update of a Pediatric Disease Diagnosed in Adults by Anna Koumarianou, Panagiota Oikonomopoulou, Margarita Baka, Dimitrios Vlachodimitropoulos, Stylianos Argentos, Theodoros Piperos, Maria-Ioanna Christodoulou, Kakoulis Theodoulou, Theodoros Mariolis-Sapsakos

“…MYCN is a well-known oncogene overexpressed in different human malignancies including neuroblastoma, rhabdomyosarcoma, medulloblastoma, astrocytoma, Wilms’ tumor, and small cell lung cancer. While neuroblastoma is one of the most common childhood malignancies, in adults it is extremely rare and its treatment is based on pediatric protocols that take into consideration stage and genotypic features, such as MYCN amplification. …”
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Financial burden of complications following lung resection: a scoping review protocol by Laurence Weinberg, Stephen Barnett, Jordan Berman, Ariane Flinkier, Fabien Chu, Hugh Slifirski, Rebecca Caragata

“…Respiratory diseases, particularly lung cancer, pose significant public health and economic challenges with thoracic surgery as the standard curative treatment. …”
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The impact of PD-L1 polymorphisms on the efficacy of immune checkpoint inhibitors depends on the tumor proportion score: a retrospective study by Keiichiro Suminaga, Takashi Nomizo, Hironori Yoshida, Hiroaki Ozasa

“…Method Patients treated with immune checkpoint inhibitor monotherapy for non-small cell lung cancer at Kyoto University Hospital until January 2023, with TPS data and biological specimens available for SNP measurement, were eligible for this study. …”
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A Case of Cavitary Lung Metastasis From Prostate Cancer by Shinnosuke Ohnaka, Mayumi Aoyama, Rino Arai, Saya Hattori, Yusuke Kubo, Shugo Suzuki, Toshihiro Yoshimura, Akinori Ebihara, Toshiaki Morikawa, Hidenobu Shigemitsu, Ichiro Kuwahira

“…ABSTRACT A 79‐year‐old man was found to have multiple nodules in the lung fields on chest computed tomography. Metastatic lung cancer was suspected; however, the primary site remained elusive. …”
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Molecular Mechanisms Contributing Bacterial Infections to the Incidence of Various Types of Cancer by Salah A. Sheweita, Awad S. Alsamghan

“…Also, intercellular infection of lungs with Chlamydia pneumoniae was found to contribute as one of the ethological factors of lung cancer. Moreover, infection of the urinary tract with Staphylococcus aureus, Klebsiella spp., and Proteus mirabilis has been found to cause bladder cancer. …”
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Characterizing microbial communities and their correlation with genetic mutations in early-stage lung adenocarcinoma: implications for disease progression and therapeutic targets by Hao-Shuai Yang, Jin Zhang, Hong-Xiang Feng, Fei Qi, Fan-Jia Kong, Wei-Jie Zhu, Chao-Yang Liang, Zhen-Rong Zhang

“…BackgroundLung adenocarcinoma (LUAD), the most prevalent form of lung cancer. The transition from adenocarcinoma in situ (AIS), and minimally invasive adenocarcinoma (MIA) to invasive adenocarcinoma (IAC) is not fully understood. …”
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The Effect of Pyrroloquinoline Quinone on the Expression of WISP1 in Traumatic Brain Injury by Yongqi Ye, Pengju Zhang, Yuhang Qian, Baoxin Yin, Meijuan Yan

“…Although some studies have confirmed that WISP1 is concerned with colon cancer and lung cancer, there is little report about the influence of WISP1 in traumatic brain injury. …”
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Extraction efficiency and bioactive evaluation of Tamarix nilotica and Arthrocnemum macrostachyum extracts for anti-cancer potential. by Maryam Al Kaabi, Nancy A ElNaker, Nila Jan, Michael A Ochsenkühn, Shady A Amin, Lina F Yousef, Ahmed F Yousef

“…Results suggest that: 1) MAE is more efficient than maceration in recovering metabolites from plant biomass based on measurements of total phenolic content, radical scavenging activity, and bioactivity of extracts based on in vitro cytotoxicity. 2) Only T. nilotica extracts were found to be bioactive based on cytotoxicity measurements. 3) Cancer cell lines displayed differential sensitivity to T. nilotica crude extracts, with breast cancer cells being the most sensitive and lung cancer cells being the least sensitive. 4) Solid-phase fractionation of T. nilotica crude extract using different percentages of methanol resulted in several fractions that were 100-fold more cytotoxic compared to the crude unfractionated extract. …”
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Somatic Mutaome Profile in Human Cancer Tissues by Nayoung Kim, Yourae Hong, Doyoung Kwon, Sukjoon Yoon

“…The majority of tissue samples harbored 20-80 different mutant genes, on average. Lung cancer samples showed a greater number of mutations in diverse genes than other cancer subtypes. …”
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