Synthesis and biological evaluation of 4-(1H-imidazol-2-yl)-2-(pyrimidin-5-yl)oxazoles as potent anticancer agents by Divya Komirishetti, Vasantha Mittapelli

“…Further, the biological applications of the newly prepared compounds 11a–j were evaluated against four human cancer cell lines including breast cancer (MCF-7), lung cancer (A549), colon cancer (Colo-205) and ovarian cancer (A2780), using the standard MTT assay, with etoposide as the positive control. …”
Get full text

Design and Analysis of thermosyphon Solar Water Heating System. by Kakuru, Stephen

“…In rural areas of Uganda, access to affordable hot water is a persistent challenge with communities often relying on firewood and charcoal for water heating which contributes to deforestation, air pollution, and health hazards hence respiratory diseases like asthma, lung cancer, TB, and allergic disease, climate changes and global warming. …”
Get full text

Methylene Blue-Aided In Vivo Staining of Central Airways during Flexible Bronchoscopy by Sabine Zirlik, Kai M. Hildner, Markus F. Neurath, Florian S. Fuchs

“…In particular, exophytic growth of lung cancer did not show any specific pattern in chromobronchoscopy. …”
Get full text

Longitudinal genomic profiling using liquid biopsies in metastatic nonsquamous NSCLC following first line immunotherapy by Haolun Ding, Min Yuan, Yaning Yang, Xu Steven Xu

“…Overall, longitudinal liquid biopsy profiling provided valuable insights into lung cancer biology post-immunotherapy, potentially guiding personalized therapies and future drug development.…”
Get full text

SH2D5 promotes lung adenocarcinoma cell metastasis and triggers EMT via activating AKT signaling pathway. by Licheng Du, Wenjia Ren, Linjun Liu, Haojia Zhu, Ke Xu, Yubai Zhou

“…Lung adenocarcinoma (LUAD) is the most common histological subtype of lung cancer, characterized by a high incidence in late stages, high mortality rate, and poor prognosis. …”
Get full text

Assessing awareness, knowledge, and perceptions of hubbly bubbly smoking health risks among South African university students by Aniekie Motloutsi, Elizabeth Lubinga

“…Most participants in the study, including both HB users 74% (129) and non-users 80% (140), were able to identify lung cancer as one of the health risks of HB smoking. …”
Get full text

High Dose Radiotherapy to Automated Implantable Cardioverter-Defibrillator: A Case Report and Review of the Literature by Inaya Ahmed, Wei Zou, Salma K. Jabbour

“…We report a case of successful full-dose chemoradiotherapy to stage IIIB nonsmall cell lung cancer (NSCLC) in a 59-year-old man with extensive cardiac history and an automated implantable cardioverter-defibrillator (AICD) located within the radiotherapeutic field. …”
Get full text

Advanced Role of Neutrophils in Common Respiratory Diseases by Jinping Liu, Zhiqiang Pang, Guoqiang Wang, Xuewa Guan, Keyong Fang, Ziyan Wang, Fang Wang

“…The traditional roles of neutrophils in severe asthma, chronic obstructive pulmonary diseases (COPD), pneumonia, lung cancer, pulmonary fibrosis, bronchitis, and bronchiolitis had already been reviewed. …”
Get full text

Role of Farnesoid X Receptor in the Pathogenesis of Respiratory Diseases by Jin-nan Wu, Jian-rong Chen, Jin-liang Chen

“…For example, FXR can regulate the tumor microenvironment by regulating the balance of inflammatory and immune responses in the body to promote the occurrence and development of non-small-cell lung cancer (NSCLC), thereby being considered a potential target for immunotherapy of NSCLC. …”
Get full text

Renal Tubular Acidosis an Adverse Effect of PD-1 Inhibitor Immunotherapy by Sandy El Bitar, Chanudi Weerasinghe, Elie El-Charabaty, Marcel Odaimi

“…We report the case of a 79-year-old female with metastatic non-small cell lung cancer on anti-PD-1 therapy nivolumab. After the 4th administration of nivolumab, the treatment course was complicated with normal anion gap metabolic acidosis. …”
Get full text

In Vitro models of leukemia development: the role of very small leukemic stem-like cells in the cellular transformation cascade by Jan Jakub Lica, Jan Jakub Lica, Joanna Jakóbkiewicz-Banecka, Andrzej Hellmann

“…In continuously growing cell lines, for the first time, our team’s follow-up research on leukemia, lung cancer, and healthy embryonic kidney cells revealed stages that resembles very small precursor stem cells. …”
Get full text

Targeting ferroptosis: a promising approach for treating lung carcinoma by Ziyang Wu, Yan Zhang, Wendi Zhong, Kunjian Wu, Tian Zhong, Tao Jiang

“…In addition, research on ferroptosis in the diagnosis and treatment of lung cancer has been growing exponentially. Therefore, it is necessary to provide a thorough summary of the latest advancements in the field of ferroptosis. …”
Get full text

X-Ray Computed Tomography: Semiautomated Volumetric Analysis of Late-Stage Lung Tumors as a Basis for Response Assessments by C. Bendtsen, M. Kietzmann, R. Korn, P. D. Mozley, G. Schmidt, G. Binnig

“…An anthropomorphic phantom with embedded model masses and 71 time points in 10 clinical cases with advanced lung cancer was analyzed using a semi-automated workflow. …”
Get full text

Diffeomorphic Registration of Images with Variable Contrast Enhancement by Guillaume Janssens, Laurent Jacques, Jonathan Orban de Xivry, Xavier Geets, Benoit Macq

“…The method is validated in the context of radiotherapy for lung cancer patients on several 4D respiratory-correlated CT scans of the thorax with and without variable contrast enhancement.…”
Get full text

Autoimmune Gastrointestinal Paralysis: Failure of Conventional Treatment without Immunomodulation by Craig Weinkauf, Sean McPhillips, Robert Krouse, Ira Levine

“…The treatment of the rare enteric nervous system (ENS) manifestations of paraneoplastic syndromes, which are most frequently associated with small cell lung cancer (SCLC), is poorly understood and described. …”
Get full text

Annexin A2 Expression in Aerogenous Metastasis of Pulmonary Invasive Mucinous Adenocarcinoma: A Case Report including Immunohistochemical Analysis by Kazumori Arai, Masahide Hirose

“…Aerogenous metastasis (AM) is a form of lung cancer that spreads in a unique fashion, but its mechanisms are still unclear. …”
Get full text

Circular RNAs in cancer: roles, mechanisms, and therapeutic potential across colorectal, gastric, liver, and lung carcinomas by Ayushi Malviya, Rajabrata Bhuyan

“…This review delves into the role of circRNAs in four key cancer types: colorectal cancer (CRC), gastric cancer (GC), liver cancer (HCC), and lung cancer (LUAD). The focus lies on their potential as cancer biomarkers and drug targets. …”
Get full text

Dynamic Tracking of Lung Deformation during Breathing by Using Particle Method by Subas Chhatkuli, Seiichi Koshizuka, Mitsuru Uesaka

“…To reduce the side effects and to improve the efficiency of radiation therapy in lung cancer, a pinpoint radiation therapy system is under development. …”
Get full text

A Rare Case of Paraneoplastic Syndrome Presented with Severe Gastroparesis due to Ganglional Loss by Konstantinos N. Argyriou, Martin Peters, Javaid Ishtiaq, Santosh Enaganti

“…In our report, so as to increase the clinical awareness of this rare clinical entity, we present the case of a 70-year-old Caucasian female who presented in our hospital with severe gastroparesis that was later proven to be associated with an overt small cell lung cancer (SCLC) and we discuss the existing knowledge of the pathophysiology, diagnosis, and management of this disorder.…”
Get full text

Impact of the crosstalk between the PTEN and PAFR as well as PAFR and EGFR pathways in cancer by Anita Thyagarajan, Zaid Sirhan, Ravi P. Sahu

“…Importantly, high tumor expression of a G-protein coupled platelet-activating factor-receptor (PAFR) is associated with increased tumor progression as well as decreased overall survival and poor prognosis in malignancies such as non-small cell lung cancer (NSCLC). Along similar lines, overactivation or mutations in epidermal growth factor receptor (EGFR) signaling are detected in various human malignancies and associated with poor prognosis. …”
Get full text