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961
Combination of Hotspot Mutations With Methylation and Fragmentomic Profiles to Enhance Multi‐Cancer Early Detection
Published 2025-01-01“…Enhanced sensitivities were observed for colorectal (81.36%) and lung cancer (82.9%). Conclusion The integration of genetic and epigenetic alterations into a multimodal assay significantly enhances the early detection of various cancers. …”
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962
Assessment of Knowledge on Side Effects Among Cancer Patients Receiving Radiotherapy in Selected Hospitals of West Bengal
Published 2025-01-01“… Background and Aim Approximately 20 million new cases of cancer and 9.7 million cancer deaths will occur in 2022. Lung cancer is the most frequently diagnosed type of cancer. …”
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963
Assessing the influence of the modifiable areal unit problem on Bayesian disease mapping in Queensland, Australia.
Published 2025-01-01“…<h4>Methods</h4>To understand the impact of the MAUP in Queensland, Australia, the present study investigates inference from simulated lung cancer incidence data using the five levels of spatial aggregation defined by the Australian Statistical Geography Standard. …”
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964
Arsenic Exposure and the Induction of Human Cancers
Published 2011-01-01“…Millions of individuals worldwide are chronically exposed through drinking water, with consequences ranging from acute toxicities to development of malignancies, such as skin and lung cancer. Despite well-known arsenic-related health effects, the molecular mechanisms involved are not fully understood; however, the arsenic biotransformation process, which includes methylation changes, is thought to play a key role. …”
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965
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966
REV7: a small but mighty regulator of genome maintenance and cancer development
Published 2025-01-01“…Given that genome instability is a hallmark of cancer, it is unsurprising that REV7, with its numerous genome maintenance roles, is implicated in multiple malignancies, including ovarian cancer, glioma, breast cancer, malignant melanoma, and small-cell lung cancer. Moreover, high REV7 expression is associated with poor prognoses and treatment resistance in these and other cancers. …”
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967
Clinical Characteristics of Choroidal Metastases
Published 2024-10-01“…The most common intraocular tumors in adults are metastases from primary tumors: breast cancer, lung cancer, and other organ neoplasms. They are most typically located in the choroid, in the posterior pole of the eye. …”
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968
Biological characterization and clinical significance of cuproptosis-related genes in lung adenocarcinoma
Published 2025-01-01“…Abstract Background Lung cancer has high morbidity and mortality rates, which results in a poor prognosis. …”
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969
Severe Erosive Pill Esophagitis Induced by Crizotinib Therapy: A Case Report and Literature Review
Published 2016-01-01“…Previous case reports have described esophagitis thought to be secondary to crizotinib, an oral tyrosine-kinase inhibitor used in the treatment of anaplastic lymphoma kinase- (ALK-) positive non-small cell lung cancer (NSCLC). In those reports, the interval development of esophagitis was between two days and three months after initiating or reinitiating crizotinib therapy. …”
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970
Cross-ViT based benign and malignant classification of pulmonary nodules.
Published 2025-01-01“…The benign and malignant discrimination of pulmonary nodules plays a very important role in diagnosing the extent of lung cancer lesions. There are many methods using Convolutional neural network (CNN) for benign and malignant classification of pulmonary nodules, but traditional CNN models focus more on the local features of pulmonary nodules and lack the extraction of global features of pulmonary nodules. …”
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971
Successful Diagnosis and Management of Superior Orbital Fissure Syndrome Secondary to Lung Adenocarcinoma: A Case Report
Published 2025-01-01“…It also demonstrates the efficacy of localized radiotherapy in treating such uncommon presentations of lung cancer metastasis.Keywords: superior orbital fissure syndrome, lung adenocarcinoma, metastasis, radiotherapy, case report…”
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972
Endometrial Carcinoma Presenting as Vasculitic Sensorimotor Polyneuropathy
Published 2011-01-01“…Paraneoplastic polyneuropathy (PNP) is mostly related to small cell lung cancer (5%), prostate, gastric, and breast cancer. …”
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973
Outcome differences by sex in oncology clinical trials
Published 2024-03-01“…The strongest differences are in trials of EGFR inhibitors in lung cancer and rituximab in non-Hodgkin’s lymphoma (both favoring females). …”
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974
Synchronous BALT Lymphoma and Squamous Cell Carcinoma of the Lung: Coincidence or Linkage?
Published 2013-01-01“…Combined chemotherapy for lung cancer and BALT lymphoma was initiated.…”
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975
Combined Effect of Lentinan and Cisplatin on Cytokines IL-6, TNF-α, and TGF-β in Tumor Therapy
Published 2019-01-01“…Furthermore, it was proved that the combined treatment of lentinan and cisplatin enhanced the inhibitory effect of cisplatin on the expression of IL-6, TNF- α, TGF-β and tumor growth in mice bearing human ovarian cancer xenograft, human prostate tumor xenograft, and human non-small cell lung cancer xenograft.…”
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976
Aligning knowledge concepts to whole slide images for precise histopathology image analysis
Published 2024-12-01“…In the application of lung cancer subtyping, breast cancer HER2 scoring, and gastric cancer immunotherapy-sensitive subtyping tasks, ConcepPath significantly outperformed previous SOTA methods, which lacked the guidance of human expert knowledge.…”
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977
Synthesis and structure elucidation of some novel thiophene and benzothiophene derivatives as cytotoxic agents
Published 2016-03-01“…The results showed that ethyl 5-amino-3-(4-chlorostyryl)-4-cyanothiophene-2-carboxylate (5b), ethyl 5-amino-4-((4-methoxyphenyl)carbonyl)-3-methylhiophene-2-carboxylate (8c) and 5-3-(ethoxy-3-oxopropanamido)-3-methyl-4-(phenylcarbamoyl)thiophene-2-carboxylate (9) were the most active compounds towards three tumor cell lines – MCF-7 (breast adenocarcinoma), NCI-H460 (non-small cell lung cancer) and SF-268 (CNS cancer) and a normal fibro-blast human cell line (WI-38) compared to the anti-proliferative effects of the reference control doxorubicin.…”
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978
Maxillary osteonecrosis linked to Pembrolizumab therapy: a case report
Published 2024-01-01“…Observation: An 83-year-old male with metastatic non-small cell lung cancer treated exclusively with Pembrolizumab developed osteonecrosis of the maxilla. …”
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979
Diversity of Epithelial Stem Cell Types in Adult Lung
Published 2015-01-01“…This paper reviews recent findings in the identification and isolation of region-specific epithelial stem/progenitor cells and local niches along the airway tree and the potential link of epithelial stem cells for the development of lung cancer.…”
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980
HCNetlas: A reference database of human cell type-specific gene networks to aid disease genetic analyses.
Published 2025-02-01“…Additionally, they suggest that many lung cancer-related genes may exert their roles in immune cells. …”
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