-
941
Myasthenia Gravis-Like Syndrome Presenting as a Component of the Paraneoplastic Syndrome of Lung Adenocarcinoma in a Nonsmoker
Published 2014-01-01“…Adenocarcinoma of the lung is the most common form of lung cancer in nonsmokers. It is commonly seen in the periphery of the lungs. …”
Get full text
Article -
942
Persistent Inflammation in Pulmonary Granuloma 48 Years after Talcage Pleurodesis, Detected by FDG-PET/CT
Published 2012-01-01“…We demonstrate a case with FDG-avid pulmonary nodules, mimicking lung cancer. After histopathological examination they appeared to be the result of persistent inflamed tissue, due to talcage pleurodesis, which occurred 48 years ago. …”
Get full text
Article -
943
Validation of polymorphic Gompertzian model of cancer through in vitro and in vivo data.
Published 2025-01-01“…In this study, we demonstrate that the polymorphic Gompertzian model successfully captures trends in both in vitro and in vivo data on non-small cell lung cancer (NSCLC) dynamics under treatment. Additionally, for the in vivo data of tumor dynamics in patients undergoing treatment, we compare the goodness of fit of the polymorphic Gompertzian model to that of the classical oncologic models, which were previously identified as the models that fit this data best. …”
Get full text
Article -
944
Colorectal cancer spectrum: From subtypes and epidemiology to oncotherapies
Published 2025-04-01“…Colorectal cancer (CRC) has an incidence rate of 10 % and is the third most common cause of mortality worldwide, following breast and lung cancer. The clinical symptoms of CRC appear in the last phases of the disease and there is a substantial golden period between the formation of polyps and the onset of cancer. …”
Get full text
Article -
945
An Anaplastic Lymphoma Kinase-positive Inflammatory Myofibroblastic Tumor with Rapidly Acquired Resistance to First-line Anaplastic Lymphoma Kinase Inhibitor: A Case and Literature...
Published 2024-01-01“…(Gly1202Arg), which is a common mechanism of drug resistance in ALK fusion-positive non-small cell lung cancer. We also report subsequent treatment choices and responses in this patient and perform a literature review regarding similar cases as this rare tumor.…”
Get full text
Article -
946
Upper Gastrointestinal Bleed due to Duodenal Metastases of Lung Adenocarcinoma: Report of Two Cases and Review of Literature
Published 2019-01-01“…Upper gastrointestinal bleeding as a result of gastrointestinal metastases from lung cancer is extremely rare. We report two cases of patients with duodenal metastases from lung adenocarcinoma presented with recurrent melena. …”
Get full text
Article -
947
CXC Chemokines in the Pathogenesis of Pulmonary Disease and Pharmacological Relevance
Published 2022-01-01“…The current review presents the understanding of the roles of CXC ligands (CXCLs) and their cognate receptors (CXCRs) in the pathogenesis of several lung diseases such as allergic rhinitis, COPD, lung fibrosis, lung cancer, pneumonia, and tuberculosis. The potential therapeutic benefits of pharmacological or other CXCL/CXCR axis manipulations are also discussed.…”
Get full text
Article -
948
Genetic evidence for the causal effects of air pollution on the risk of respiratory diseases
Published 2025-01-01“…Results: TSMR analysis revealed that exposure to PM2.5 increased the risk of early-onset chronic obstructive pulmonary disease (COPD), pneumonia, pulmonary embolism and lung cancer. PM2.5–10 exposure was associated with an increased risk of lung cancer, while PM10 exposure increased the risk of pneumonia and bronchiectasis. …”
Get full text
Article -
949
Clinical characteristics and outcomes of surgical resection for brain metastases from lung adenocarcinoma
Published 2025-01-01“…Only 5 patients (2.4%) had received lung cancer treatment before craniotomy. The intracranial location of BM was mostly in the frontal lobe (54, 26.0%) and the metastatic sites were mostly single (117, 56.3%); the metastatic tumor size was mostly between 2-5 cm (141, 67.8%). …”
Get full text
Article -
950
The Suppression of Signal Transducer and Activator of Transcription-3 in A549 human Lung Carcinoma Cells Induced by Marine Sponge Callyspongia aerizusa
Published 2025-01-01“…Previous analysis showed the cytotoxic impact of Callyspongia aerizusa (C. aerizusa) extract containing ergost-22-en-3-one and ergost-7-en3-ol against A549 lung cancer cells, with an IC50 value of 9.38 μg/mL. …”
Get full text
Article -
951
Opsoclonus-myoclonus syndrome in the course of teratoma: a case report
Published 2025-01-01“…This syndrome is usually immune-mediated and may be the first manifestation of cancer as a paraneoplastic syndrome, most often occurring in the course of breast, ovarian or lung cancer. Here we show a case of a 20-year-old woman with symptomatic opsoclonus-myoclonus syndrome in the course of teratoma. …”
Get full text
Article -
952
Radiation Pneumonitis after Radiotherapy of Neck Lymphoma
Published 2014-01-01“…In routine work, radiation pneumonitis (RP) is the most significant complication of acute treatment-related toxicities in lung cancer; however, serious radioactive pneumonia is rare for the radiotherapy of neck lymphoma because the volume of the lungs affected by radiation dose was very small. …”
Get full text
Article -
953
Characterizing mutation-treatment effects using clinico-genomics data of 78,287 patients with 20 types of cancers
Published 2024-12-01“…Leveraging the large number of identified predictive mutations, we developed a machine learning model to generate a risk score for response to immunotherapy in patients with advanced non-small cell lung cancer (aNSCLC). Through rigorous computational analysis of large-scale clinico-genomic real-world data, this research provides insights and lays the groundwork for further advancements in precision oncology.…”
Get full text
Article -
954
The role of tribbles homolog 2 in cell proliferation
Published 2025-01-01“…TRIB2 is not only involved in the physiological proliferation of cells (granulosa cells, myoblasts, naive T cells, and thymocytes) during normal development but also in the pathological proliferation of vascular smooth muscle cells and a variety of cancer cells (lung cancer cells, liver cancer cells, leukemia cells, pancreatic cancer cells, gastric cancer cells, prostate cancer cells, thyroid cancer cells, cervical cancer cells, melanoma cells, colorectal cancer cells, ovarian cancer cells and osteosarcoma cells) under disease conditions. …”
Get full text
Article -
955
Sintilimab for the treatment of lung adenocarcinoma-induced immune-related hypophysitis: a case report
Published 2025-01-01“…This report describes a case of a lung cancer patient who, after receiving chemotherapy in combination with the programmed death-1 (PD-1) inhibitor sintilimab, presented with systemic fatigue, alterations in mental and behavioral patterns, somnolence, and symptoms of diabetes insipidus, leading to a diagnosis of grade 4 immune-related hypophysitis. …”
Get full text
Article -
956
Case Report: Metastatic involvement of the acromioclavicular joint in a patient with papillary carcinoma of the ureter
Published 2025-01-01“…Ureteral papillary carcinoma is a rare subtype of urothelial carcinoma, ranking fourth among cancers following prostate (or breast) cancer, lung cancer, and colorectal cancer. Although previous studies have documented bone metastases mainly in the pelvis, spine, ribs, and femur, this case report presents the first recorded instance of metastasis occurring in the acromioclavicular joint. …”
Get full text
Article -
957
Metastases to the Thyroid Presenting as a Metabolically Inactive Incidental Thyroid Nodule with Stable Size in 15 Months
Published 2014-01-01“…A 63-year-old male with history of adenocarcinoma of the right lobe lung (5 years prior to presentation), treated with surgery and chemotherapy, followed by new adenosquamous lung cancer in the left lobe of the lung (one year prior to presentation), treated surgically followed by adjuvant chemotherapy, was referred to Endocrinology section for evaluation of an incidental thyroid nodule on CT chest. …”
Get full text
Article -
958
Methods for preliminary determination of pemetrexed in macromolecular drug-carrier systems
Published 2016-03-01“…Pemetrexed (PMX) is an antifolate drug utilized in the treatment of non-small cell lung cancer. For studies of potential macromolecular carriers for PMX, fast and precise methods were developed to determine the bound and free drug contained in investigated conjugate preparations. …”
Get full text
Article -
959
Complete Disappearance of Choroidal Metastasis from Lung Adenocarcinoma Treated with Bevacizumab and Chemotherapy
Published 2015-01-01“…Choroidal metastasis from lung cancer is uncommon. We report a case of choroidal metastasis as an inaugural manifestation of lung adenocarcinoma, successfully treated by docetaxel, cisplatinum, and intravenous bevacizumab as an antiangiogenesis therapy. …”
Get full text
Article -
960
Navigating the Evolving Treatment Paradigm for _EGFR_-Mutant NSCLC
Published 2024-10-01“…In non-small cell lung cancer (NSCLC), the most prevalent driver mutations in epidermal growth factor receptor (_EGFR_) are deletions in exon 19 (Ex19del) and L858R mutations in exon 21, which comprise approximately 90% of all _EGFR_ mutations. …”
Get full text
Article