MCF-DTI: Multi-Scale Convolutional Local–Global Feature Fusion for Drug–Target Interaction Prediction by Jihong Wang, Ruijia He, Xiaodan Wang, Hongjian Li, Yulei Lu

“…Our case study demonstrates that our model effectively validated several known drug–target relationships in lung cancer and predicted the therapeutic potential of certain preclinical compounds in treating lung cancer. …”
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Smoking Cessation in Chinese Patients Undergoing Thoracic Surgery: A Multicenter Prospective Observational Study by Jianxing He, Dingpei Han, Kun Qian, Weijie Guan, Ge Zhang, Weiqing Lu, Hecheng Li, Xiuyi Zhi

“…Results Of the 276 enrolled patients, 213 (77.2%) were smokers and 63 (22.8%) were quitters; 76.4% were diagnosed with primary lung cancer. PCs occurred in 13.8% of patients, with similar proportions in smokers (14.1%) and quitters (12.7%). …”
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Clofarabine induces tumor cell apoptosis, GSDME-related pyroptosis, and CD8+ T-cell antitumor activity via the non-canonical P53/STING pathway by Jing Chen, Jie Wu, Xiang Chen, Qian Tao, Nian Liu, Cong Peng, Can Lu, Qiuqiu Li

“…Clinical data sets were used to analyze the correlation between stimulator of interferon genes (STING)-NFκB signaling and immune infiltration.Results In this study, Clo significantly reduced the growth of melanoma and lung cancer cells. Furthermore, Clo treatment induced GSDME-mediated pyroptosis. …”
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Large Language Model Approach for Zero-Shot Information Extraction and Clustering of Japanese Radiology Reports: Algorithm Development and Validation by Yosuke Yamagishi, Yuta Nakamura, Shouhei Hanaoka, Osamu Abe

“…ObjectiveThis study aimed to develop and evaluate an algorithm that uses large language models (LLMs) to extract information from Japanese lung cancer radiology reports and perform clustering analysis. …”
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Disease-Specific Target Gene Expression Profiling of Molecular Imaging Probes: Database Development and Clinical Validation by Lawrence Wing-Chi Chan, Connie Hiu-Ching Ngo, Fengfeng Wang, Moss Y. Zhao, Mengying Zhao, Helen Ka-Wai Law, Sze Chuen Cesar Wong, Benjamin Yat-Ming Yung

“…The DIPP database was validated with a clinical positron emission tomography (PET) study on lung cancer and an in vitro study on neuroendocrine cancer. …”
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A Rare Case of Penile Metastases as a Harbinger of Primary Pulmonary Adenosquamous Carcinoma by Partha Hota, Tejas N. Patel, Xiaofeng Zhao, Carrie Schneider, Omar Agosto

“…Although lung cancer has a high propensity for distant metastatic disease, penile metastases from primary lung neoplasms are considered particularly rare. …”
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Mucoepidermoid Carcinoma of the Lung: A Case Report and Literature Review by S. Alsidawi, J. C. Morris, K. A. Wikenheiser-Brokamp, S. L. Starnes, N. A. Karim

“…Mucoepidermoid carcinoma (MEC) of the lung is a rare form of lung cancer that is classified into low grade and high grade based on histological features. …”
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No Apparent Workup for most new Indeterminate Pulmonary Nodules in US Commercially-Insured Patients by Bruce S. Pyenson, Carol M. Bazell, Michael J. Bellanich, Melissa A. Caplen, Javier J. Zulueta

“…**Background:** A recent study estimated that more than 1.5 million Americans have an indeterminate pulmonary nodule (IPN) identified on a chest computed tomography (CT) scan each year outside of lung cancer screening programs. However, the cost and pattern of subsequent IPN workup have not been described for real-world settings. …”
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Primary pulmonary meningioma: a case report and literature review by Jun Cheng, Chunfen Guo

“…Clinical and radiological diagnoses are often challenging, especially distinguishing from primary lung cancer. Surgery remains the optimal choice for the diagnosis and treatment of PPM. …”
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Adaptive genetic algorithm based deep feature selector for cancer detection in lung histopathological images by Avigyan Roy, Priyam Saha, Nandita Gautam, Friedhelm Schwenker, Ram Sarkar

“…The source code for this work can be found https://github.com/priyam-03/GA-Feature-Selector-Lung-Cancer .…”
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In Vitro Model for Studying Malignancy Associated Changes by Xiao Rong Sun, Yonghong Zheng, Calum MacAulay, Stephen Lam, Alexei Doudkine, Branko Palcic

“…An in vitro cell culture model system was designed to study interactions between non‐small cell lung cancer (NSCLC) and the normal bronchial epithelium of the human respiratory tract in vivo to see if the MAC‐like phenomenon can be detected in such a system. …”
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Increased PPARD Expression May Play a Protective Role in Human Lung Adenocarcinoma and Squamous Cell Carcinoma by Yong Zhu, Yedong Mi, Zhonghua Qin, Xuewei Jiang, Yibo Shan, Kamil Kural, Guiping Yu

“…Peroxisome proliferator-activated receptor-δ, encoded by gene PPARD, is overexpressed in a majority of human lung cancer subtypes, but its role in the tumor progression remains poorly understood. …”
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The discovery and characterization of K‐563, a novel inhibitor of the Keap1/Nrf2 pathway produced by Streptomyces sp by Ran Hori, Kozo Yamaguchi, Hidetaka Sato, Miwa Watanabe, Kyoko Tsutsumi, Susumu Iwamoto, Masayuki Abe, Hideyuki Onodera, Satoshi Nakamura, Ryuichiro Nakai

“…K‐563 also exerted synergistic combinational effects with lung cancer chemotherapeutic agents. An in vivo study in mice xenotransplanted with A549 cells to further explore the therapeutic potential of K‐563 revealed that it also inhibited Keap1/Nrf2 pathway in lung cancer tumors. …”
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Identification of cancer cell-intrinsic biomarkers associated with tumor progression and characterization of SFTA3 as a tumor suppressor in lung adenocarcinomas by Yu Zhao, Chengcheng Zhou, Ling Zuo, Haoming Yan, Yuhan Gu, Hong Liu, Guiping Yu, Xiaorong Zhou

“…Abstract Background Recent advancements in contemporary therapeutic approaches have increased the survival rates of lung cancer patients; however, the long-term benefits remain constrained, underscoring the pressing need for novel biomarkers. …”
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Hospice Care by Suzanna Smith

“…“Recently a friend’s mother, Alice, was diagnosed with lung cancer, and even though she received all the possible treatments, the cancer was incurable. …”
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Hospice Care by Suzanna Smith

“…“Recently a friend’s mother, Alice, was diagnosed with lung cancer, and even though she received all the possible treatments, the cancer was incurable. …”
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Squeeze-and-Excitation Vision Transformer for Lung Nodule Classification by Xiaozhong Xue, Yanhe Ma, Weiwei Du, Yahui Peng

“…Lung cancer is one of the deadliest cancers. Early diagnosis of lung cancer can increase the 5-year survival rate to 70%, and the lung nodule classification is the basis for early diagnosis. …”
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Are Onconeural Antibodies a Clinical Phenomenology in Paraneoplastic Limbic Encephalitis? by Hongliang Zhang, Chunkui Zhou, Limin Wu, Fengming Ni, Jie Zhu, Tao Jin

“…Most of these clinical syndromes in adults are associated with lung cancer, especially small cell lung cancer (SCLC), lymphoma, and gynecological tumors. …”
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A Novel In Situ Dendritic Cell Vaccine Triggered by Rose Bengal Enhances Adaptive Antitumour Immunity by Lanlin Zhang, Jiangyuan Du, Qian Song, Chufan Zhang, Xianghua Wu

“…This study reveals that the RB-iDC vaccine can synergistically destroy the primary tumour, inhibit distant metastasis, and prevent tumour relapse in a lung cancer mouse model, which provides important preclinical data for the development of a novel combinatorial immunotherapy.…”
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A lung nodule segmentation model based on the transformer with multiple thresholds and coordinate attention by Tianjiao Hu, Yihua Lan, Yingqi Zhang, Jiashu Xu, Shuai Li, Chih-Cheng Hung

“…The experimental results demonstrated its high practical value for the early diagnosis of lung cancer.…”
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