Machine learning identifies the association between second primary malignancies and postoperative radiotherapy in young-onset breast cancer patients. by Yulin Lai, Peiyuan Huang

“…YWBC patients receiving PORT had significantly greater risks of second primary solid malignancies (SPSMs, RR = 1.61), including breast cancer (RR = 1.89), lung cancer (RR = 2.12) and thyroid cancer (RR = 1.48), but not second primary hematologic malignancies (RR = 1.32; 0.94-1.88). …”
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Screening of multi deep learning-based de novo molecular generation models and their application for specific target molecular generation by Yishu Wang, Mengyao Guo, Xiaomin Chen, Dongmei Ai

“…Moreover, we evaluated the performance of these NLP-based generation models and another new model architecture based on a selective state space and selected the best approach jointing a transfer learning strategy for de novo drug discovery to target L858R/T790M/C797S-mutant EGFR in non-small cell lung cancer.…”
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Quantum computational infusion in extreme learning machines for early multi-cancer detection by Anas Bilal, Muhammad Shafiq, Waeal J. Obidallah, Yousef A. Alduraywish, Haixia Long

“…Results demonstrate that Q-GBGWO-ELM improves diagnostic accuracy by an average of 6.5% compared to traditional methods, with notable accuracy rates across various cancers: 98.80% for breast cancer, 92.30% for brain tumors, 97.00% for skin cancer, and 96.98% for lung cancer. The model integrates advanced feature extraction and optimization techniques, indicating significant potential for early cancer detection. …”
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Clinical benefits of the 5th intercostal incision in uniportal VATS for female patients by Dalin Wang, Zhilin Luo, Jia Ming

“…A retrospective analysis of 150 female lung cancer patients was conducted, divided into 4 and 5th intercostal incision groups (n = 75 each). …”
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Evaluation of anticancer potency of Cu-isatin-1-(2-pyridyl) piperazine thiosemicarbazone (Cu-Istpypz) against epidermoid carcinoma cell line (A431) by Indranil Banerjee, Piyush Kumar, Narendra K. Singh, Paras N. Yadav, Yuba Raj Pokharel

“…Among the compounds synthesized, copper conjugated isatin-thiosemicarbazone derivative, Cu-Istpypz, showed considerable anti-proliferative activity against A431 (Skin Cancer) and A549 (Lung Cancer) cell lines. Cell viability assay using crystal violet dye exhibited the effects of the compounds against those cell lines. …”
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OPN Polymorphism Is Related to the Chemotherapy Response and Prognosis in Advanced NSCLC by Yanzhang Hao, Jianwei Liu, Ping Wang, Feng Wang, Zeshun Yu, Mianli Li, Shaoshui Chen, Fangling Ning

“…Osteopontin (OPN) is associated with prognosis of patients with non-small-cell lung cancer (NSCLC). However, little is known about the association between OPN gene polymorphism and the chemotherapy response in NSCLC patients. …”
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A cross-sectional survey on the effects of ambient temperature and humidity on health outcomes in individuals with chronic respiratory disease by Samantha Mekhuri, Shirley Quach, Caroline Barakat, Winnie Sun, Mika L Nonoyama

“…., asthma, sleep apnea, interstitial lung disease, lung cancer) and residing in Canada for ≥ 1 year. Negative responders to weather extremes were *a priori* defined as having a change of ≥ 2 points in the CAT…”
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Unraveling relationship between the genetic polymorphism CYP2A13 and nicotine metabolism of male smokers in Medan, Indonesia by Noni Novisari Soeroso, Rozaimah Zain-Hamid, Syamsul Bihar, Chaliza Soliha, Fannie Rizki Ananda, Aida

“…CYP2A13, a key enzyme in nicotine and xenobiotic metabolism, is implicated in tobacco smoke-related lung cancer. Aim This study investigated the association between CYP2A13 genetic polymorphism and nicotine metabolism in male smokers in Medan, Indonesia. …”
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Artificial Neural Network-Based System for PET Volume Segmentation by Mhd Saeed Sharif, Maysam Abbod, Abbes Amira, Habib Zaidi

“…Experimental and Monte Carlo simulated PET phantom data sets and clinical PET volumes of nonsmall cell lung cancer patients were utilised to validate the proposed algorithm which has demonstrated promising results.…”
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Significantly Delayed Development of Polyarthritis with Active Tenosynovitis after Possible Temporary Neutropenic Immune-Related Adverse Events Caused by Atezolizumab Treatment: A... by Yoshitaka Saito, Yoh Takekuma, Hajime Asahina, Ryo Hisada, Mitsuru Sugawara

“…Here, we report a case of significantly delayed rheumatic irAEs (Rh-irAEs) with prior possible temporary neutropenic irAEs in a patient with atezolizumab-treated non-small-cell lung cancer and its management. A man in his sixties received atezolizumab monotherapy as the sixth-line treatment. …”
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The Use of Porous Scaffold as a Tumor Model by Mei Zhang, Philip Boughton, Barbara Rose, C. Soon Lee, Angela M. Hong

“…High-density low-volume seeding was used to promote attachment of a non-small-cell lung cancer cell line (NCI-H460) to scaffolds. Growth patterns in 3D culture were compared with those of monolayers. …”
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Canine lung carcinoma—A descriptive review by Aleksandra Marcinowska, Aleksandra Marcinowska, Rodrigo Dos Santos Horta, Felisbina Queiroga, Felisbina Queiroga, Antonio Giuliano, Antonio Giuliano, Antonio Giuliano

“…Primary lung cancer is a relatively uncommon tumor in dogs, accounting for about 1% of all canine malignancies. …”
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Image Characterization of Cancer of the Colon by Thaimi Conde Cueto, Martha Yudey Rodríguez Pino, Pedro Juan Barrios Fuentes, Bárbara Aleida García Hernández, Julio Suz Piña, Nery M. Díaz Yanes

“…<strong>Background:</strong> Cancer of the colon is the second cause of death due to cancer worldwide, alter lung cancer in males and breast cancer in females. It is not possible to confirm the patient’s diagnosis without the result of image tests such as barium enema, ultrasound cytology or biopsy of the lesion. …”
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Feasibility of Using High-Resolution Computed Tomography Features for Invasiveness Differentiation of Malignant Nodules Manifesting as Ground-Glass Nodules by Xinyue Chen, Benbo Yao, Juan Li, Chunxiao Liang, Rui Qi, Jianqun Yu

“…Ground-glass nodule (GGN)-like adenocarcinoma is a special subtype of lung cancer. The invasiveness of the nodule correlates well with the patient’s prognosis. …”
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p53 dosage can impede KrasG12D- and KrasQ61R-mediated tumorigenesis. by Özgün Le Roux, Jeffery I Everitt, Christopher M Counter

“…Loss of the Trp53 gene encoding the tumor suppressor p53 enhances the ability of oncogenic Kras to initiate tumorigenesis in carcinogen and genetic models of lung cancer. Conversley, an extra copy of Trp53 (Super p53) was recently shown to suppress Kras-induced tumorigenesis in a genetic model of this disease. …”
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Implications of the Incidental Finding of a MYCN Amplified Adrenal Tumor: A Case Report and Update of a Pediatric Disease Diagnosed in Adults by Anna Koumarianou, Panagiota Oikonomopoulou, Margarita Baka, Dimitrios Vlachodimitropoulos, Stylianos Argentos, Theodoros Piperos, Maria-Ioanna Christodoulou, Kakoulis Theodoulou, Theodoros Mariolis-Sapsakos

“…MYCN is a well-known oncogene overexpressed in different human malignancies including neuroblastoma, rhabdomyosarcoma, medulloblastoma, astrocytoma, Wilms’ tumor, and small cell lung cancer. While neuroblastoma is one of the most common childhood malignancies, in adults it is extremely rare and its treatment is based on pediatric protocols that take into consideration stage and genotypic features, such as MYCN amplification. …”
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The impact of PD-L1 polymorphisms on the efficacy of immune checkpoint inhibitors depends on the tumor proportion score: a retrospective study by Keiichiro Suminaga, Takashi Nomizo, Hironori Yoshida, Hiroaki Ozasa

“…Method Patients treated with immune checkpoint inhibitor monotherapy for non-small cell lung cancer at Kyoto University Hospital until January 2023, with TPS data and biological specimens available for SNP measurement, were eligible for this study. …”
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A Case of Cavitary Lung Metastasis From Prostate Cancer by Shinnosuke Ohnaka, Mayumi Aoyama, Rino Arai, Saya Hattori, Yusuke Kubo, Shugo Suzuki, Toshihiro Yoshimura, Akinori Ebihara, Toshiaki Morikawa, Hidenobu Shigemitsu, Ichiro Kuwahira

“…ABSTRACT A 79‐year‐old man was found to have multiple nodules in the lung fields on chest computed tomography. Metastatic lung cancer was suspected; however, the primary site remained elusive. …”
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Molecular Mechanisms Contributing Bacterial Infections to the Incidence of Various Types of Cancer by Salah A. Sheweita, Awad S. Alsamghan

“…Also, intercellular infection of lungs with Chlamydia pneumoniae was found to contribute as one of the ethological factors of lung cancer. Moreover, infection of the urinary tract with Staphylococcus aureus, Klebsiella spp., and Proteus mirabilis has been found to cause bladder cancer. …”
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The Effect of Pyrroloquinoline Quinone on the Expression of WISP1 in Traumatic Brain Injury by Yongqi Ye, Pengju Zhang, Yuhang Qian, Baoxin Yin, Meijuan Yan

“…Although some studies have confirmed that WISP1 is concerned with colon cancer and lung cancer, there is little report about the influence of WISP1 in traumatic brain injury. …”
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