Improving glycemic control by transitioning from the MiniMedTM 640G to 770G in Japanese adults with type 1 diabetes mellitus: a prospective, single-center, observational study by Satoshi Kubota, Ai Sato, Manami Hosokawa, Yosuke Okubo, Shohei Takayama, Atsuko Kaneko, Yasuho Shimada, Yuki Asano, Yoshihiko Sato, Masanori Yamazaki, Mitsuhisa Komatsu

“…The effectiveness of a hybrid closed-loop (HCL) system in improving glycemic control is unclear in Japanese individuals. …”
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Safety and Feasibility of Transanal Endoscopic Surgery for Diffuse Cavernous Hemangioma of the Rectum by Ziwei Zeng, Xianrui Wu, Junji Chen, Shuangling Luo, Yujie Hou, Liang Kang

“…After admission, all the patients underwent transanal endoscopic surgery and four patients had simultaneous loop ileostomy. The mean operative time was 278 min (range 168-400 min). …”
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Sinking Skin Flap Syndrome following Posttraumatic Hydrocephalus by Ashish Chugh, Prashant Punia, Sarang Gotecha

“…These 3 patients were treated via rehydration using normal saline (NS) till the Central Venous Pressure (CVP) equaled 8–10 cm of water, nursing in Trendelenburg position and shunt occlusion using silk 3-0 round bodied suture tied over a “C”-loop of VP shunt tube over clavicle. This was followed by cranioplasty within 2 days of presentation using a flattened, nonconvex artificial Polymethyl Methacrylate (PMMA) bone flap with central hitch suture taken across the bone flap and release of shunt tie in immediate postoperative period. …”
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Combined multi-scale characterization of pores in ultra-thick coal seams of Jurassic Xishanyao Formation, Tiaohu-Malang sags, Santanghu Basin by Yue CHEN, Qiqi LEI, Dongmin MA, Xin WANG, Xinggang WANG, Diefang HUANG, Gaoxiang RONG

“…Its liquid nitrogen adsorption curves correspond to type Ⅱ with a H4 hysteresis loop. For the 9-2 coal sample, the fractal dimensions of micropores and small pores are 2.53 and 2.63, respectively, indicating higher complexity and better permeability connectivity. …”
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University proceedings. Volga region. Natural sciences by O.V. Chernyshova, N.A. Kartavov, R.A. Ilyin, S.V. Titov

“…On the territory of Ulyanovsk region 9 colonies were surveyed: 6 combined and 6 single–species colonies were surveyed: 6 – joint (characterized by separation of species by microstations), 3 – mixed (without separation), 3 – S. suslicus and 3 – S. major. 60 individuals of both species and possible interspecific hybrids were captured and tagged in the colonies Molecular genetic studies were performed on 5 markers (D-loop, Hoxb5, p53, ZfX, SmcY). The sound signals and color indicators of 11 large, 11 speckled ground squirrels, 5 interspecific hybrids and female speckled ground squirrels 2036* were analyzed. …”

Entrepreneurial Budgeting in the Iranian Government Budget: Obstacles and Solutions by Seyyed Mohammad Moghimi, Alireza Salmanian

“…The success of entrepreneurial budgeting is based on its previous performance budgeting, which requires articulating the mission, measurable objectives, performance actions for efficiency and effectiveness, and feedback loops for utilization through citizen satisfaction surveys and focused groups. …”
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GPR137-RAB8A activation promotes ovarian cancer development via the Hedgehog pathway by Chao Tang, Lin Li, Chongying Zhu, Qiang Xu, Zihao An, Shouying Xu, Chao Lin

“…By RNA-sequencing and experiments in vitro using multiple ovarian cancer cell models as well as in vivo using subcutaneous xenografts assay and in situ transplantation ovarian cancer model in nude mice, we further demonstrated that RAB8A positively mediated OC progression through activating HH signaling pathway by disassociating the protein–protein complex formation of GLI and SuFu (Suppressor of Fused), which reciprocally enhanced GPR137 activity, forming a regulation loop between HH signaling and GPR137. Conclusions Collectively, this study depicts the role of GPR137-RAB8A-HH cascade in the development of OC, deepening our understanding of tumor biomechanics regarding OC progression and providing novel targets for OC therapy in future.…”
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Lateral Extra-Articular Tenodesis as an Adjunct to ACL Reconstruction by Madeline M. McGovern MD, Sercan Yalcin MD, Natalie A. Lowenstein MPH, Jillian L. Mazzocca BA, Elizabeth G. Matzkin MD, Giovanna Medina MD, PhD

“…The graft is passed inside the suture loop with an additional knot tied over the top using the needled suture. …”
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Genetic inbreeding load and its individual prediction for milk yield in French dairy sheep by Simona Antonios, Silvia T. Rodríguez-Ramilo, Andres Legarra, Jean-Michel Astruc, Luis Varona, Zulma G. Vitezica

“…A fraction of 99.1% of the partial inbreeding coefficients were lower than 0.01 in all breeds, meaning that in practice inbreeding occurs in pedigree loops that span several generations backwards. Less than 5% ancestors generate inbreeding, because mating is essentially between unrelated individuals. …”
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Genome-Wide Identification and Expression Analysis of bHLH-MYC Family Genes from Mustard That May Be Important in Trichome Formation by Jianzhong Li, Guoliang Li, Caishuo Zhu, Shaoxing Wang, Shifan Zhang, Fei Li, Hui Zhang, Rifei Sun, Lingyun Yuan, Guohu Chen, Xiaoyan Tang, Chenggang Wang, Shujiang Zhang

“…It was demonstrated that the MYB-bHLH-WD40 (MBW) ternary complex consists of MYB, basic Helix-Loop-Helix (bHLH), and WD40-repeat (WD40) family proteins and plays a key role in regulating trichome formation and density. …”
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Functional near-infrared spectroscopy for the assessment and treatment of patients with disorders of consciousness by Nan Wang, Nan Wang, Nan Wang, Yifang He, Sipeng Zhu, Dongsheng Liu, Xiaoke Chai, Xiaoke Chai, Qiheng He, Tianqing Cao, Jianghong He, Jingqi Li, Juanning Si, Yi Yang, Yi Yang, Yi Yang, Yi Yang, Yi Yang, Yi Yang, Yi Yang, Jizong Zhao, Jizong Zhao

“…Specifically, it investigates the potential value of combining fNIRS with brain-computer interfaces (BCIs) and closed-loop neuromodulation systems for patients with DoC, aiming to elucidate mechanisms that promote neurological recovery.MethodsA systematic analysis was conducted on 155 studies published between January 1993 and October 2024, retrieved from the Web of Science Core Collection database.ResultsAnalysis of 21 eligible studies on neurological diseases involving 262 DoC patients revealed significant findings. …”
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Sex-based differences in the long-term fate of hippocampal neurons born after a traumatic brain injury by Hannah C. Downing, Hannah C. Downing, Ashley B. Glover, Jessica E. Gebhardt, Jessica E. Gebhardt, Katherine L. Thompson, Kathryn E. Saatman, Kathryn E. Saatman, Kathryn E. Saatman

“…Ascl1 is a basic helix-loop-helix transcription factor transiently expressed in NPCs and activated NSCs in the dentate gyrus of the adult mammalian brain. …”
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A novel minimally invasive neurosurgical cranial fixation device for improved accuracy of intraventricular catheter placement: an experimental animal study by Atai Daniel, Matan Coronel, Segev Peer, Ben Grinshpan, Soner Duru, Jose L. Peiro, James L. Leach, Elena Abellán, Carolyn M. Doerning, David Zarrouk, Francesco T. Mangano

“…Additionally, the EVD catheter pull test was conducted with the addition of a safety loop which did not allow movement of the EVD to a force of 3.6kgf. …”
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Four weeks of slow-paced breathing: a longitudinal, randomized, placebo-controlled study of the autonomic nervous system by Nicolas Bourdillon, Arnaud Rochat, Vanessa Hoop, Grégoire P. Millet

“… Introduction The autonomic nervous system (ANS) relies on two essential feedback loops: respiratory sinus arrythmia (RSA) and arterial baroreflex which are both regulated by a complex interplay of sympathetic and parasympathetic activations. …”
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Asymptomatic Post-Traumatic Rupture of the Right Diaphragm Dome by E. A. Losik, M. V. Fadeeva, V. V. Shchegelsky, R. T. Rzaev, A. V. Stepanov, K. B. Puzakov, M. R. Skhirtladze

“…In the right thoracic cavity, anterior to the liver, were the loops of the intestine and the outlet of the stomach.More than 30 years before, the patient had experienced an explosive trauma, which might have caused a rupture in the right dome of the diaphragm. …”
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Outcomes of patients after successful left ventricular assist device explantation: a EUROMACS study by Christiaan F.J. Antonides, Felix Schoenrath, Theo M.M.H. deBy, Rahatullah Muslem, Kevin Veen, Yunus C. Yalcin, Ivan Netuka, Jan Gummert, Evgenij V. Potapov, Bart Meyns, Mustafa Özbaran, David Schibilsky, Kadir Caliskan, the EUROMACS investigators

“…Beta‐blockers were prescribed to 85%, angiotensin‐converting enzyme inhibitors to 71%, and loop diuretics to 50% of the patients, respectively. …”
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Coinfection of avian hepatitis E virus and different serotypes of fowl adenovirus in chicken flocks in Shaanxi, China by Yuan Zhang, Huanyu Xu, Yinuo Tian, Jirong Tang, Huanqing Lin, Yani Sun, Qin Zhao, En-Min Zhou, Yiyang Chen, Baoyuan Liu

“…Phylogenetic analysis based on the hexon loop-1 gene showed that these isolates were clustered into three distinct serotypes: FAdV serotype 4 (FAdV-4), FAdV-8a, and FAdV-8b. …”
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Toward a circular carbon economy: Production of green C1 compounds through high-temperature CO2 electrolysis by Nan Zheng, Jing Zhu, Haitao Zhu, Jin Xuan, Haoran Xu, Meng Ni

“…Broader context: The carbon cycle economy is an approach that focuses on managing and reducing carbon emissions through a loop system that encompasses reducing, reusing, recycling, and removing. …”
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Eu:CROPIS AIV Program: Challenges and Solutions for a Spin-Stabilized Satellite Containing Biology by Toni Delovski, Catherin Düvel, Fabian Greif, Ansgar Heidecker, Sebastian Kottmeier, Olaf Mierheim, Falk Nohka, Fabian Orlowski-Feldhusen

“…Its primary payload focuses on the research of closed-loop biological, regenerative life support systems, in a simulated gravitational environment of the Moon and Mars over months at a time. …”
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Mitochondrial reactive oxygen species trigger metformin-dependent antitumor immunity via activation of Nrf2/mTORC1/p62 axis in tumor-infiltrating CD8T lymphocytes by Kazuhiro Kakimi, Hirokazu Matsushita, Masaaki Komatsu, Eiryo Kawakami, Mikako Nishida, Nahoko Yamashita, Taisaku Ogawa, Keita Koseki, Eiji Warabi, Tomoyuki Ohue, Katsuyuki Shiroguchi, Heiichiro Udono

“…Nrf2 activates mTORC1, whereas mTORC1 activates Nrf2 in a p-p62(S351)-dependent manner, thus creating a feedback loop that ensures CD8TILs’ proliferation. In combination with anti-PD-1 Ab, Met stimulates robust proliferation of CD8TILs and IFN-γ secretion, resulting in an IFN-γ-dependent reprogramming of the tumor microenvironment.…”
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