Dynamic Changes of Th1 Cytokines and the Clinical Significance of the IFN-γ/TNF-α Ratio in Acute Brucellosis by Guang Xu, Peng Zhang, Rongjing Dang, Yanfang Jiang, Feng Wang, Bin Wang, Mingyuan Yang

“…The IFN-γ/TNF-α ratio may be a feasible parameter for assessing clinical severity, yet further longitudinal studies of the immunization and inflammatory reaction of brucellosis are needed in larger patient populations.…”
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Development of a short version of the perceived social support scale: based on classical test theory and ant colony optimization by Yunchou Wu, Jingqi Tang, Zhuoran Du, Ke Chen, Fei Wang, Xiaonan Sun, Guoying Zhang, Yibo Wu

“…Conclusions In future research, if a short form of the MSPSS scale is needed for measurement purposes, the 3-item short form is suitable for clinical settings, large-scale cross-sectional studies, or longitudinal studies, while the PSSS-A6 is more appropriate for more precise measurements. …”
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Characterizing pediatric discharge diagnoses associated with daily extreme heat exposure in the Midwestern US: A retrospective case-crossover study by Sarah Oerther, Zachary Phillips, Zidong Zhang, Joanne Salas, Sarah Farabi, Tamara Otey

“…Future research should focus on longitudinal studies to explore these dynamics further and develop effective heat mitigation strategies to protect vulnerable pediatric populations from the adverse effects of extreme heat.…”
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Risk Factors Influencing Cognitive Function in Elderly Patients With Late‐Life Depression: A Scoping Review by Ping Jiang, Yunfeng Gao, Lin Wang, Xiaojun Shao, Lei Zhang, Gang Zhu, Li Duan

“…These comprised five longitudinal studies, nine pathological controlled studies, five cross‐sectional studies, two cohort studies, and one randomized controlled study. …”
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Characterization of tumor evolution by functional clonality and phylogenetics in hepatocellular carcinoma by Zeynep Kacar, Eric Slud, Doron Levy, Julián Candia, Anuradha Budhu, Marshonna Forgues, Xiaolin Wu, Arati Raziuddin, Bao Tran, Jyoti Shetty, Yotsawat Pomyen, Jittiporn Chaisaingmongkol, Siritida Rabibhadana, Benjarath Pupacdi, Vajarabhongsa Bhudhisawasdi, Nirush Lertprasertsuke, Chirayu Auewarakul, Suleeporn Sangrajrang, Chulabhorn Mahidol, Mathuros Ruchirawat, Xin Wei Wang

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Short-Term and Long-Term Effects of Bariatric Surgery on Diabetic Retinopathy: A Systematic Review by Erika Butkutė, Monika Zieniūtė, Agnė Morkūnaitė, Vilma Jūratė Balčiūnienė

“…Rapid glycemic changes after surgery may pose risks of DR progression. Large-scale, longitudinal studies are needed to clarify the role of BS in DR progression and regression.…”
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Cross-Sectional Analysis of IL-6, TNF-α, Adiponectin, Leptin, and Klotho Serum Levels in Relation to BMI Among Overweight and Obese Children Aged 10–14 in La Rioja, Spain by Beatriz Fernández-Vallejo, Francisco Jiménez Monteagudo, Lourdes Romero, Maria Isabel López Aznárez, María del Carmen Romero Cobas, Laura Pérez-Martínez

“…Conclusions: This study underscores leptin and the L/A ratio as potential biomarkers of metabolic dysregulation in childhood obesity, particularly in females. Longitudinal studies are needed to confirm these findings and assess the clinical utility of these biomarkers in pediatric obesity management.…”
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The study of pubertal stage and age of menarche in girls in Isfahan province, Iran by Nafiseh Mozafarian, Mahin Hashemipour, Mohammad Reza Maracy, Masoumeh Pourrajab, Razieh Omidi, Roya Kelishadi

“…Nationally representative surveys and longitudinal studies are necessary to determine the exact age of puberty for future international comparisons.…”
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Predictive value of bile acids as metabolite biomarkers for gallstone disease: A systematic review and meta-analysis. by Xu Han, Juan Wang, Yingnan Wu, Hao Gu, Ning Zhao, Xing Liao, Miao Jiang

“…Yet, further validation of these biomarkers by longitudinal studies is still warranted in the future. PROSPERO registration number CRD42022339649.…”
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Risk of Dementia and Its Associated Factors Among the Patients With Coronary Artery Disease Attending a Tertiary Cardiac Hospital of Dhaka City: A Cross‐Sectional Study by Fardina Rahman Omi, Lingkan Barua, Palash Chandra Banik, Syed Mosfiqur Rahman, Mithila Faruque

“…Conclusion A substantial proportion of patients with CAD had a future risk of dementia which demands an urgent risk reduction strategy in Bangladesh. Future longitudinal studies may more precisely justify the current findings.…”
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The Impact of Chronic Pelvic Pain and Bowel Morbidity on Quality of Life in Cervical Cancer Patients Treated With Radio (Chemo) Therapy. A Systematic Literature Review by Natuhwera G, Ellis P

“…There is limited population-based and longitudinal research about the topic, and on chronic pelvic pain in general, which limits generalisability. Longitudinal studies with more extended periods of follow-up are needed.Keywords: chronic pelvic pain, bowel morbidity, cervical cancer, quality of life, radio (chemo) therapy…”
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Association of Albumin‐To‐Creatinine Ratio With Diabetic Retinopathy Among US Adults (NHANES 2009–2016) by Han Dai, Ling Liu, Weiwei Xu

“…Comprehensive evaluation of renal function and glycaemic control biomarkers, considering age‐ and comorbidity‐specific patterns, could improve DR risk prediction and management. Future longitudinal studies should validate these findings, particularly in identified high‐risk subgroups, and investigate underlying mechanisms, potentially advancing personalised DR prediction and management strategies.…”
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Impact of a Virtual Reality Intervention on Stigma, Empathy, and Attitudes Toward Patients With Psychotic Disorders Among Mental Health Care Professionals: Randomized Controlled Tr... by Jing Ling Tay, Yuanrong Qu, Lucas Lim, Rohan Puthran, Chye Lee Robert Tan, Rajkirren Rajendran, Ker Chiah Wei, Huiting Xie, Kang Sim

“…ConclusionsBoth the intervention and control VR groups of mental health care professionals showed improvements in attitudes, stigma, and social distance toward people with psychotic disorders. Future longitudinal studies may want to evaluate the impact of VR on caregivers and the public on these same and other outcome measures to reduce stigma and improve empathy toward individuals with psychotic disorders. …”
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Students Perceptions, Satisfactions and Challenges on Problem-Based Learning (PBL): A Survey Study Among Final Year Pharmacy Students by Engku Nuraishah Huda E. Zainudin, Fakhira Damia Khaidir, May Khin Soe, Nurul Asyiqin Yusof, Khairool Azizul Mohammad

“…Future research should consider diverse student populations, conduct longitudinal studies, and explore instructors’ perspectives. …”
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Clinical Correlations of Novel Autoantibodies in Patients with Dry Eye by Sezen Karakus, Alan N. Baer, Esen K. Akpek

“…Whether these patients have an early stage of SS or a different type of autoimmune condition may be determined through longitudinal studies.…”
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Early Detection of Microvascular Changes in Patients with Diabetes Mellitus without and with Diabetic Retinopathy: Comparison between Different Swept-Source OCT-A Instruments by Stela Vujosevic, Caterina Toma, Edoardo Villani, Valentina Gatti, Marco Brambilla, Andrea Muraca, Maria Chantal Ponziani, Gianluca Aimaretti, Alessandro Nuzzo, Paolo Nucci, Stefano De Cilla’

“…Further, larger longitudinal studies are needed to better understand microvascular damage at very early stages of diabetic retinal disease and to define the strengths and weaknesses of different OCT-A devices.…”
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Dietary index for gut microbiota and its protective role against kidney stones: evidence of diabetes as a mediator from NHANES cross-sectional data by Lei Wang, Junjun Wu, Ziwen Jiang, Chao Wang, Fuxiang Lin, Yuxiang Zhong, Pengpeng Zhao, Wei Wei, Jianhua Huang, Zhanping Xu

“…These findings highlight the role of dietary interventions targeting gut microbiota in KS prevention and call for longitudinal studies to confirm these results and develop tailored dietary strategies.…”
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Analysis of Genetic Variation in CD40 and CD40L: Relationship with mRNA Relative Expression and Soluble Proteins in Acute Coronary Syndrome by D. E. Martínez-Fernández, J. R. Padilla-Gutiérrez, F. Casillas-Muñoz, Emmanuel Valdés-Alvarado, Brenda Parra-Reyna, Maricela Aceves-Ramírez, J. F. Muñoz-Valle, U. Zalapa Flores, J. C. Chávez Herrera, Y. Valle

“…Due to the important roles of the CD40-CD40L system in the pathogenesis of ACS, longitudinal studies are required to determine if soluble levels of CD40 and CD40L could be clinically useful markers of a recurrent cardiovascular event after an ACS.…”
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Tracking Persistent Symptoms in Scotland (TraPSS): a longitudinal prospective cohort study of COVID-19 recovery after mild acute infection by Jane Ormerod, Nicholas F Sculthorpe, Marie McLaughlin, Luke Cerexhe, Eilidh Macdonald, Antonio Dello Iacono, Nilihan E M Sanal-Hayes, Joanne Ingram, Rachel Meach, David Carless, Lawrence D Hayes

“…To understand the complexity of Long-COVID, the importance of symptom surveillance and prospective longitudinal studies is evident.Methods A 9-month longitudinal prospective cohort study was conducted within Scotland (n=287), using a mobile app to determine the proportion of recovered individuals and those with persistent symptoms and common symptoms, and associations with gender and age.Results 3.1% of participants experienced symptoms at month 9, meeting the criteria for Long-COVID, as defined by the National Institute for Health and Care Excellence terminology. …”
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Parental Technoference and Child Problematic Media Use: Meta-Analysis by Jinghui Zhang, Qing Zhang, Bowen Xiao, Yuxuan Cao, Yu Chen, Yan Li

“…Specifically, the association was stronger when both parents engaged in technoference compared to when only 1 parent did, and in cross-sectional studies compared to longitudinal studies. Age, gender, publication status, and type of problematic media use did not significantly moderate the relationship (all P>.05). …”
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