Dairy intake and cognitive function in older adults in three cohorts: a mendelian randomization study by Natalia Ortega, Nick J. Mueller, Abbas Dehghan, Tosca O. E. de Crom, Armin von Gunten, Martin Preisig, Pedro Marques-Vidal, Marco Vinceti, Trudy Voortman, Nicolas Rodondi, Patricia O. Chocano-Bedoya

“…Methods We included 43,836 individuals over 55 years old with genotyping, dietary data, and cognitive function measurements from three population-based studies: CoLaus|PsyCoLaus (Switzerland), the Rotterdam Study (the Netherlands) and the Canadian Longitudinal Study on Aging (CLSA - Canada). We performed a one-sample Mendelian randomization using two-stage least-squares regression. …”
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Cancer mortality and sectors of employment: a cohort study in Italy by Stefania Massari, Lisa Bauleo, Claudio Gariazzo, Paola Michelozzi, Luca Dei Bardi, Nicolas Zengarini, Sara Maio, Massimo Stafoggia, Marina Davoli, Giovanni Viegi, Giulia Cesaroni, Alessandro Marinaccio, on behalf of the BIGEPI Collaborative Group

“…Methods We used a cohort from the Rome Longitudinal Study (ROL) and linked it with the National Social Insurance Agency (INPS) database to obtain working histories. …”
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Association of over-the-counter mouthwash use with markers of nitric oxide metabolism, inflammation, and endothelial function—a cross-sectional study by Kai Guo, Kaumudi Joshipura, Karina Ricart, Rakesh P. Patel, Barbara A. Gower, Oelisoa Mireille Andriankaja, Evangelia Morou-Bermudez

“…We hypothesize that nitrates/nitrites are associated with these biomarkers, and that their associations would vary with the frequency of mouthwash use.MethodOur cross-sectional study used data and specimen from the baseline of the San Juan Overweight Adult Longitudinal Study (SOALS). Robust Gamma regression with log-link function, Spearman correlations and partial correlations adjusted for covariates were used for the analysis.ResultsUsing OTC mouthwash twice a day or more was significantly associated with lower serum nitrite levels compared to less frequent use (β = −0.357, 95% CI: −0.650, −0.064), but not with other markers of inflammation and endothelial function. …”
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Association between DNA methylation levels of thioredoxin-interacting protein (TXNIP) and changes in glycemic traits: a longitudinal population-based study by Keisuke Maeda, Ryosuke Fujii, Hiroya Yamada, Eiji Munetsuna, Mirai Yamazaki, Yoshitaka Ando, Genki Mizuno, Hiroaki Ishikawa, Koji Ohashi, Yoshiki Tsuboi, Yuji Hattori, Yuya Ishihara, Nobuyuki Hamajima, Shuji Hashimoto, Koji Suzuki

“…We therefore examined the association between TXNIP DNAm levels and longitudinal changes in glycemic traits by conducting a longitudinal study involving 169 subjects who underwent two health checkups in 2015 and 2019. …”
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Current trends in e-mental health interventions: Health care providers' attitudes and usage patterns by Elena Caroline Weitzel, Katja Schladitz, Maria Schwenke, Franziska Dinah Welzel, Georg Schomerus, Peter Schönknecht, Markus Bleckwenn, Anja Mehnert-Theuerkauf, Steffi G. Riedel-Heller, Margrit Löbner

“…Methods: Data for this explorative analysis derive from a longitudinal study of N = 335 health care providers from four professional groups in German mental health care (GPs, specialist doctors, psychotherapists, and clinicians). …”
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Factors associated with decreased anal sphincter tone and the accuracy of forced anal examinations to detect individuals having receptive anal intercourse: an observational study by John A Schneider, Alan G Nyitray, Derek Smith, Michael W Ross, Elizabeth Y Chiao, Timothy J Ridolfi, Bridgett Brzezinski, B R Simon Rosser, Aniruddha Hazra, Jenna Nitkowski, Sandrine Sanos, Ever Mkonyi, Lucy Mgopa

“…Using baseline data from a longitudinal study, we aimed to determine factors associated with sphincter tone and the accuracy of sphincter tonality to detect persons engaging in receptive anal intercourse.Methods Clinicians in Chicago, Houston and Milwaukee, USA conducted digital anal rectal examinations (DARE) to score sphincter resting tone (RT) and squeeze tone (ST). …”
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How trait mindfulness protects late adolescents from stress-induced sleep problems: the unique role of mindfulness facets and gender differences by Huiting Cao, Jing Qian, Fenghua Tang, Yunyan Dong, Haining Ren, Xiaoran Xue, Ningning Mao, Xiaoyu Liu

“…While previous research has demonstrated the potential protective effect of trait mindfulness, facets of mindfulness were found to have unique functions against the negative impact of stress, and the unique impact of each facet of mindfulness on the sleep problems caused by the negative impact of stress remains unclear. Thus, this longitudinal study aimed to assess the impact of stressful life events on sleep problems a year later among late adolescents and to explore the moderating effects of the five trait mindfulness facets. …”
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Elucidating epigenetic landscape of gastric premalignant lesions through genome‐wide mapping of 5‐hydroxymethylcytosines: A 12‐year median follow‐up study by Zhongguang Luo, Wenshuai Li, Wanwei Zheng, Yixiang Shi, Maolin Ye, Xiangyu Guo, Kaiyi Fu, Changsheng Yan, Bowen Wang, Bin Lv, Shaocong Mo, Hongyang Zhang, Jun Zhang, Chuan He, Feifei Luo, Wei Zhang, Jie Liu

“…Methods To our knowledge, we conducted the largest and longest longitudinal study of a Chinese population with gastric precursor lesions, involving 29,176 patients with gastritis who underwent gastroscopy and biopsy between 2001 and 2015, with follow‐up until 1 August, 2022. …”
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Assessment of six insulin resistance surrogate indexes for predicting stroke incidence in Chinese middle-aged and elderly populations with abnormal glucose metabolism: a nationwide... by Luqing Jiang, Tengxiao Zhu, Wenjing Song, Ying Zhai, Yu Tang, Fengxia Ruan, Zichen Xu, Lei Li, Xia Fu, Daoqin Liu, Aidong Chen, Qiwen Wu

“…Methods Data from the China Health and Retirement Longitudinal Study (CHARLS) were analysed in this study. …”
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Unravelling the role of secretory Immnuoglobulin-A in COVID-19: a multicentre study in nursing homes during the first wave by Rafael Bielza, Patricia Pérez, Nuria García, Laura Ballesteros-Sanabria, Rosa María Martínez, Azam Ghazi, Clara Hernando, María Victoria Rodríguez, Israel J. Thuissard, Cristina Andreu-Vázquez, José Manuel Bautista

“…Methods In this multicentre longitudinal study, conducted in two NHs attended in coordination with a hospital-based Geriatric team, 305 residents (87.3 years, 74.4% female) were included. …”
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Blood-based epigenome-wide association study and prediction of alcohol consumption by Elena Bernabeu, Aleksandra D. Chybowska, Jacob K. Kresovich, Matthew Suderman, Daniel L. McCartney, Robert F. Hillary, Janie Corley, Maria Del C. Valdés-Hernández, Susana Muñoz Maniega, Mark E. Bastin, Joanna M. Wardlaw, Zongli Xu, Dale P. Sandler, Archie Campbell, Sarah E. Harris, Andrew M. McIntosh, Jack A. Taylor, Paul Yousefi, Simon R. Cox, Kathryn L. Evans, Matthew R. Robinson, Catalina A. Vallejos, Riccardo E. Marioni

“…The final EpiScore was trained on 16,717 individuals and tested in four external cohorts: the Lothian Birth Cohorts (LBC) of 1921 and 1936, the Sister Study, and the Avon Longitudinal Study of Parents and Children (total N across studies > 10,000). …”
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Responsible research in health disparities using the Adolescent Brain Cognitive DevelopmentSM (ABCD) study by MR Gonzalez, C Cardenas-Iniguez, DE Linares, S Wonnum, K Bagot, EJ White, A Cuan, S DiMatteo, YD Akiel, P Lindsley, JC Harris, E Perez-Amparan, TD Powell, Comité Organizador Latino de City Heights (COLCH), G Dowling, D Alkire, WK Thompson, TM Murray

“…Purpose: The Adolescent Brain Cognitive DevelopmentSM (ABCD) Study is the largest longitudinal study on brain development and adolescent health in the United States. …”
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‘It is scary to pause treatment’: perspectives on HIV cure-related research and analytical treatment interruptions from women diagnosed during acute HIV in Durban, South Africa: So... by Deli Mthimkhulu, Krista L. Dong, Mzwakhe Wiseman Ngcobo, Deborah Mindry, Ayanda Zulu, Ntombifuthi Langa, Luyanda Maphalala, Vanessa Pillay, Maud Mthembu, Annie Miall, Whitney Tran, Ana Dillen, Fang Wan, Ali Ahmed, Jamila K. Stockman, Maryam Hussain, Thumbi Ndung’u, Karine Dubé

“…Objective To examine the perspectives of young women diagnosed with acute HIV in a longitudinal study, focusing on their perceptions on ATI-inclusive HIV cure trials and the barriers and facilitators to participation. …”
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The REpeated ASSEssment of SurvivorS in intracerebral haemorrhage: protocol for a multicentre, prospective observational study by Daniel Woo, Richard Thompson, Carl D Langefeld, Nichol McBee, Daniel Hanley, Matthew L Flaherty, Lauren Sansing, Karen Lane, Lee A Gilkerson, Achala Vagal, Nathan Walborn, Wendy Ziai, Noeleen Ostapkovich, Kevin Triene, Timothy David Howard

“…The second strategy is the current non-surgical standard of care using data from controls in MISTIE III and ENRICH and comparative data from The Ethnic/Racial Variations of ICH (ERICH) studyextended into the ERICH-Longitudinal study, which followed over 900 of ERICH cases with serial cognitive examinations. …”
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Development and validation of a hyperlipidemia risk prediction model for middle-aged and older adult Chinese using 2015 CHARLS data by Li-xiang Zhang, Shan-Bing Hou, Fang-fang Zhao, Ting-ting Wang, Ying Jiang, Xiao-juan Zhou, Jiao-yu Cao

“…ObjectiveTo develop and validate a predictive model for hyperlipidemia risk among middle-aged and older adult individuals in China, this study aims to offer an effective screening tool for identifying those at risk.MethodsIn this study, we included 6,629 middle-aged and older adult individuals, aged 45 and above, who met the inclusion criteria from the 2015 China Health and Retirement Longitudinal Study (CHARLS) as our research subjects. Utilizing the LASSO regression and multivariate Logistic regression method, we analyzed the independent risk factors associated with hyperlipidemia among these subjects. …”
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Multiomics unravels the complexity of male obesity: a prospective observational study by Georgios E. Papadakis, Lucie Favre, Yassine Zouaghi, Nathalie Vionnet, Nicolas J. Niederländer, Michela Adamo, James S. Acierno, Dassine Berdous, Alexia Boizot, Jenny Meylan, Julijana Ivanisevic, Emmanuelle Paccou, Hector Gallart-Ayala, Tim Reyns, Elise Van Caeneghem, Bruno Lapauw, Jérôme Pasquier, Yasser Aleman, Styliani Mantziari, Olivier Salamin, Raul Nicoli, Tiia Kuuranne, Tom Fiers, Patric Hagmann, Federico Santoni, Andrea Messina, Nelly Pitteloud

“…Following RYGB-induced substantial weight loss, testosterone levels markedly increased in both obese individuals with and without HH, challenging the current definition of hypogonadism. A longitudinal study in a subset of men with obesity following bariatric surgery revealed a unique FGF21 trajectory with a sharp peak at one month post-RYGB that correlated with metabolic and reproductive improvements. …”
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Antimicrobial drug use and its association with antimicrobial resistance in fecal commensals from cows on California dairies by Essam M. Abdelfattah, Essam M. Abdelfattah, Pius S. Ekong, Emmanuel Okello, Emmanuel Okello, Tapakorn Chamchoy, Betsy M. Karle, Randi A. Black, Wagdy ElAshmawy, Wagdy ElAshmawy, David Sheedy, Deniece R. Williams, Terry W. Lehenbauer, Terry W. Lehenbauer, Barbara A. Byrne, Sharif S. Aly, Sharif S. Aly

“…(ES) from the feces of dairy cows in California (CA). A longitudinal study was conducted on ten dairies, and a random sample of cattle (late pregnant heifers and dry cows) stratified by each herd’s parity distribution were followed monthly from close-up to 120 days in milk during fall to winter 2018 (winter season) and spring to summer 2019 (summer season). …”
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Decrease in phase angle after Roux-en-Y gastric bypass is related to increase of anti-inflammatory status by Amanda Cristina Araújo Gomes, Amanda Machado Fiorotti, Amanda Motta de Bortoli, Beatriz Bobbio de Brito, João Arthur Souza Fiorido, Luciane Bresciani Salaroli, Andressa Bolsoni Lopes, Fabiano Kenji Haraguchi

“…Methods: This is a prospective longitudinal study with patients from the Bariatric and Metabolic Surgery Program of a university hospital. …”
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Association of Cardiovascular Risk Factors With Major and Minor Electrocardiographic Abnormalities: A Report From the Cross‐Sectional Phase of Tehran Cohort Study by Pooria Ahmadi, Sajjad Ahmadi‐Renani, Parmida Sadat Pezeshki, Sepehr Nayebirad, Arash Jalali, Akbar Shafiee, Aryan Ayati, Arian Afzalian, Farshid Alaeddini, Soheil Saadat, Farzad Masoudkabir, Ali Vasheghani‐Farahani, Saeed Sadeghian, Mohamamdali Boroumand, Abbasali Karimi, Boshra Pourbashash, Kaveh Hosseini, Frits R. Rosendaal

“…Methods We used the Tehran cohort study baseline data, an ongoing multidisciplinary, longitudinal study designed to identify cardiovascular disease risk factors in the adult population of Tehran. …”
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Vδ2 T-cells response in people with Mpox infection: a three-month longitudinal assessment by Eleonora Cimini, Eleonora Tartaglia, Francesco Messina, Andrea Coppola, Valentina Mazzotta, Massimo Tempestilli, Giulia Matusali, Stefania Notari, Annalisa Mondi, Gianluca Prota, Alessandra Oliva, Carla Fontana, Enrico Girardi, Fabrizio Maggi, Andrea Antinori

“…Fourteen MSM subjects (5 PWH, 35.7%) were enrolled in a longitudinal study from May to July 2022. Blood samples were collected in the early phase of infection (T1, T2) and at 3 months (T3M) post-symptom onset. …”
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