Prognostic Role of Platelet-to-Lymphocyte Ratio in Hepatocellular Carcinoma with Different BCLC Stages: A Systematic Review and Meta-Analysis by Wan-fu Lin, Mao-feng Zhong, Yu-ren Zhang, Huan Wang, He-tong Zhao, Bin-bin Cheng, Chang-quan Ling

“…The role of platelet-to-lymphocyte ratio (PLR) in the prognosis of hepatocellular carcinoma (HCC) patients with different Barcelona Clinic Liver Cancer (BCLC) stages remains controversial. This systematic review and meta-analysis aimed to determine the efficacy of PLR on HCC prognosis. …”
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AdipoR1 enhances the radiation resistance via ESR1/CCNB1IP1/cyclin B1 pathway in hepatocellular carcinoma cells by Yuhan Gan, Linhui Zhu, Yimo Li, Ruoting Ge, Jiahe Tian, Yuxin Chen, Xiang He, Shumei Ma, Xiaodong Liu

“…Our previous study revealed that Adiponectin Receptor 1 (AdipoR1) is involved in regulating radiation resistance in liver cancer patients treated with stereotactic body radiotherapy. …”
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High Expression of Ten Eleven Translocation 1 Is Associated with Poor Prognosis in Hepatocellular Carcinoma by Haopeng Wen, Tengfei Ji, Liteng Lin, Nan Cheng, Kangshun Zhu, Liangqi Cao

“…However, the effect of DNA demethylation enzymes, ten eleven translocation (TET) proteins, has not been comprehensively characterized in liver cancer. In this research, we sought to unravel the linkage of TET proteins with prognosis, immune characteristics and biological pathways in hepatocellular carcinoma (HCC). …”
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Antiviral therapy can effectively suppress irAEs in HBV positive hepatocellular carcinoma treated with ICIs: validation based on multi machine learning by Shuxian Pan, Zibing Wang

“…The accuracy of the model is verified in the DCA curve.ResultsA total of 274 HBV-related liver cancer patients were enrolled in the study. Predictive models were constructed using three machine learning algorithms to analyze and statistically evaluate clinical characteristics, including immune cell data. …”
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Bibliometric analysis of rhein in the treatment of tumors by Lan Jiang, Lan Jiang, Lan Jiang, Qian Huang, Zhongquan Shi, Yi Yang

“…It has inhibitory effects on liver cancer, breast cancer, lung cancer, oral cancer, gastric cancer, and other cancers. …”
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Knowledge of Healthcare Professionals Regarding Hepatitis B in Rania Hospitals by Zhino Raouf Ali, Mohammed Rasol Ahmed, Khalid Muhamad Hamad, Zhiar Hussen Wsu

“…It is a potentially life-threatening condition because leads to liver infection, and liver cancer. There is a shortage of research on undergraduate students. …”
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Collagen fibers quantification for liver fibrosis assessment using linear dichroism photoacoustic microscopy by Yang Qiu, Honghui Li, Kun Yu, Jiali Chen, Li Qi, Yinghua Zhao, Liming Nie

“…Liver fibrosis represents a progressive pathological condition that can culminate in severe hepatic dysfunction, potentially advancing to cirrhosis and liver cancer. The extent of liver fibrosis is intrinsically associated with the quantity of collagen fibers. …”
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Hepatitis B virus hijacks MRE11-RAD50-NBS1 complex to form its minichromosome. by Kaitao Zhao, Jingjing Wang, Zichen Wang, Mengfei Wang, Chen Li, Zaichao Xu, Qiong Zhan, Fangteng Guo, Xiaoming Cheng, Yuchen Xia

“…Chronic hepatitis B virus (HBV) infection can significantly increase the incidence of cirrhosis and liver cancer, and there is no curative treatment. The persistence of HBV covalently closed circular DNA (cccDNA) is the major obstacle of antiviral treatments. cccDNA is formed through repairing viral partially double-stranded relaxed circular DNA (rcDNA) by varies host factors. …”
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Causal Mediation Analyses for the Natural Course of Hepatitis C: A Prospective Cohort Study by Yi-Ting Huang, Yao-Chun Hsu, Hwai-I Yang, Mei-Hsuan Lee, Tai-Hsuan Lai, Chien-Jen Chen, Yen-Tsung Huang

“…Results: In 18,972 participants with 934 HCV infection, we observed that 54.1% of HCV-induced mortality was mediated by intrahepatic diseases, such as liver cirrhosis and liver cancer, and 45.9% of mortality was mediated by extrahepatic diseases. …”
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Refining MR-guided thermal ablation for HCC within the Milan criteria: a decade of clinical outcomes and predictive modeling at a single institution by Fu-Qun Wei, Pei-Shu Huang, Bing Zhang, Rui Guo, Yan Yuan, Jin Chen, Zheng-Yu Lin

“…Abstract Background The appropriateness of ablation for liver cancer patients meeting the Milan criteria remains controversial. …”
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Synthesis of thiophene and N-substituted thieno[3,2-d] pyrimidine derivatives as potent antitumor and antibacterial agents by Hafez Hend N., Alsalamah Sulaiman A., El-Gazzar Abdel-Rhman B. A.

“…Most of the newly synthesized compounds were evaluated for their in vitro activity against three human tumor cell lines, namely, liver cancer (HepG-2), colon cancer (HT-29) and lung cancer (NCI-H460), using doxorubicin as standard. …”
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A Seven-Year Retrospective Study on the Surveillance of Hepatitis B in Laos by Phimpha Paboriboune, Thomas Vial, François Chassagne, Philavanh Sitbounlang, Sengaloun Soundala, Stéphane Bertani, Davone Sengmanothong, Francois-Xavier Babin, Nicolas Steenkeste, Paul Dény, Pascal Pineau, Eric Deharo

“…Lao PDR is one of the most highly endemic countries for hepatitis B in Asia and the second country for liver cancer incidence. Therefore, the follow-up of infected individuals through predictive serological markers is of utmost importance to monitor the progression of the pathology and take the decision on treatment. …”
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Human umbilical cord derived-mesenchymal stem cells alleviate lipid metabolism disturbances of hepatocytes via mitochondrial transport by Jing Xue, Xiangnan Hu, Suying Xia, Pengfei Ren, Aihong Wang

“…Objective: To explore the effect and mechanism of human umbilical cord derived-mesenchymal stem cells (UC-MSCs) on improving lipid metabolism disorders in vitro. Methods: Human liver cancer cell line HepG2 cells were divided into three groups: normal group, oleic acid treatment group (OA group), and OA ​+ ​MSCs group. …”
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Normal tissue radioprotection by amifostine via Warburg-type effects by Michael I. Koukourakis, Alexandra Giatromanolaki, Christos E. Zois, Dimitra Kalamida, Stamatia Pouliliou, Ilias V. Karagounis, Tzu-Lan Yeh, Martine I. Abboud, Timothy D. W. Claridge, Christopher J. Schofield, Efthimios Sivridis, Costantinos Simopoulos, Savvas P. Tokmakidis, Adrian L. Harris

“…These findings shed new light on the mechanism of amifostine cytoprotection and encourage clinical research with this agent for the treatment of primary and metastatic liver cancer.…”
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Inter-organ metabolic interaction networks in non-alcoholic fatty liver disease by Yu-Hong Fan, Siyao Zhang, Ye Wang, Hongni Wang, Hongliang Li, Hongliang Li, Hongliang Li, Lan Bai

“…NAFLD may progress through several stages, including simple steatosis (NAFL), non-alcoholic steatohepatitis (NASH), cirrhosis, and potentially liver cancer. This disease is closely associated with metabolic disorders driven by overnutrition, with key pathological processes including lipid dysregulation, impaired lipid autophagy, mitochondrial dysfunction, endoplasmic reticulum (ER) stress, and local inflammation. …”
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Comprehensive analysis of inhibin-β A as a potential biomarker for gastrointestinal tract cancers through bioinformatics approaches by Rohit Kumar Verma, Prashant Kumar Srivastava, Ashutosh Singh

“…Significant differences in INHBA expression were noted in adenocarcinomas of the colon, pancreas, rectum, and stomach, while no such differences were observed in cholangiocarcinoma and liver cancer. Moreover, a comprehensive bioinformatics analysis has been done to demonstrate that the differences in expression levels are significantly related to pathological tumor stages and prognosis in different GI tract cancers. …”
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Biological activity research of male papaya flowers Carica papaya L. on some common cancer cell lines by Ngô Thị Phương Dung, Nguyễn Hoàng Dũng

“…Using the MTT method, the extract fractions also exhibited cytotoxic activity against HepG2 liver cancer cells, K562 leukemia cells, and B16F10 skin cancer cells. …”
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Exploring Glypican-3 targeted CAR-NK treatment and potential therapy resistance in hepatocellular carcinoma. by Lei Yang, Kien Pham, Yibo Xi, Qunfeng Wu, Dongfang Liu, Keith D Robertson, Chen Liu

“…Hepatocellular carcinoma (HCC) is the most prevalent form of primary liver cancer and the second leading cause of cancer-related mortality globally. …”
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Non-alcoholic fatty liver disease: comparative assessment of diagnostic and treatment approaches in the Russian Federation and People’s Republic of China by M. Ch. Semenistaya, Fan Jian-Gao, O. B. Velichenko, Ye. A. Kuznetsova, Ch. S. Pavlov

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Exploring the association between pro-inflammatory diets and chronic liver diseases: evidence from the UK Biobank by Lili Pan, Lili Pan, Zhengrong Xu, Yining Li, Guoen Cai, Haibing Gao, Shenglong Lin

“…Competing risk analyses, which accounted for cirrhosis, liver cancer, and death, supported these findings. Subgroup analyses confirmed the robustness of the DII's association across various demographic and lifestyle factors. …”
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