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7281
First microscopic and molecular identification of Cryptosporidium spp. in fat sand rats (Psammomys obesus) in Egypt and their potential zoonotic implications
Published 2025-01-01“…The samples were initially screened for the presence of Cryptosporidium spp. using light and scanning electron microscopy to characterize the parasite’s oocysts. …”
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7282
Confocal Microscopy for Detection of Intracellular Bacteria in Urine Samples of patients Suspected with Urinary Tract Infection: A Cross-sectional Observational Study
Published 2025-02-01“…Urine samples were screened for detection of Gram-negative intracellular bacteria by using light microscopy. Urine samples showing intracellular gram-negative bacteria by Gram staining were further processed for fluorescence confocal microscopy followed by conventional culture and virulence detection by multiplex Polymerase Chain Reaction (PCR). …”
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7283
L’aqueduc du Gier : nouvelles données sur le pont-siphon de Beaunant à Sainte-Foy-lès-Lyon (Métropole de Lyon)
Published 2023-12-01“…Fifteen arches remain today.The excavation, motivated by the improvement in the state of the river, revealed the opus quadratum foundations at the base of two piers (17 and 19) and uncovered the well-preserved remains of a wooden frame used to carry out the opus caementicium for the foundation block of pier 18.On the right bank of the river, this operation made it possible, against all odds, to bring to light the foundation block of pier 17, whose 38° tilt easterly testifies to the violence of the bridge collapse. …”
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7284
Elucidating the effects of manganese on the growth and cadmium accumulation of OsNRAMP5 mutant rice
Published 2025-02-01“…Thus, the results demonstrated the greater Mn-deficiency sensitivity and higher Mn requirement of ZA7 compared to ZZ35, shedding new light on the wider application of OsNRAMP5 mutant rice under different Mn conditions.…”
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7285
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7286
Single-cell RNA sequencing and AlphaFold 3 insights into cytokine signaling and its role in uveal melanoma
Published 2025-01-01“…CRISPR-Cas9 screening analysis identified hub genes and cytokine pathways with low gene effect scores across cell lines, indicating their potential importance in UVM.ConclusionThis study identified critical cellular subtypes and prognostic biomarkers in UVM, shedding light on targeted therapies. The insights into cytokine signaling and T-cell dynamics within the UVM microenvironment provide a foundation for developing personalized therapeutic strategies to improve patient outcomes.…”
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7287
Reverberation Evidence for Stream Collision and Delayed Disk Formation in Tidal Disruption Events
Published 2025-01-01“…To distinguish between these models, we investigated the continuum reverberation behaviors for ~30 TDEs with high-quality multiband light curves. We found that over half of them exhibit a positive lag by a few days in UV/optical bands, indicating that their inferred sizes are significantly larger than the envelope sizes in reprocessing. …”
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7288
An aggregation-induced emission-active lysosome hijacker: Sabotaging lysosomes to boost photodynamic therapy efficacy and conquer tumor therapeutic resistance
Published 2025-04-01“…Furthermore, QM-DMAC effectively generates reactive oxygen species (ROS) under white light irradiation, which precisely induces ROS-mediated lysosomal membrane permeabilization (LMP) and lysosome rupture. …”
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7289
Navigating the Ice: Establishing Pre-Concussion Baselines in Ice-Hockey Players for Gait Assessment Utilizing Inertial Measurement Units
Published 2025-01-01“…Discussion/Conclusion Our results will shed light on the reliability and validity of using inertial measurements in the context of concussion management. …”
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7290
Changes of Narrative: Osvald Sirén’s Photographic Modeling of Modern Research on Chinese Garden
Published 2025-01-01“…The expressiveness of Osvald Sirén’s individual works attempts to take into account all such elements as the complexity of gardens, the wandering line of sight brought about by scatter perspectives, the flow of light and the emphasis on the artistic conception of rocks. …”
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7291
Recommendation for the use of respiratory syncytial virus vaccines
Published 2025-02-01“…This recommendation should be subject to modification in light of additional medical research findings in the future, and these provisions should not be cited as a basis for dispute resolution.…”
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7292
The transcriptional regulator Lrp activates the expression of genes involved in the biosynthesis of tilimycin and tilivalline enterotoxins in Klebsiella oxytoca
Published 2025-01-01“…Our results underscore a molecular mechanism by which TM and TV production by toxigenic K. oxytoca strains is regulated and shed further light on developing strategies to prevent the intestinal illness caused by this enteric pathogen.…”
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7293
A universal gelation strategy of bivalent anions to construct nanofibrous lysozyme hydrogels for immunomemory anti‐recurrence of diabetic wound infection by activating the cGAS‐STI...
Published 2025-01-01“…In addition, near‐infrared light‐mediated photothermal characteristics are endowed with LZF to enhance its inhibitory activity of multidrug‐resistant bacteria by the skeleton modification with genipin to produce genipin‐conjuagted LZF (GLZF). …”
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7294
Signatures of lower respiratory tract microbiome in children with severe community-acquired pneumonia using shotgun metagenomic sequencing
Published 2025-02-01“…Species-level shotgun metagenomic sequencing facilitates the exploration of potentially pathogenic or protective microbes and shed the light of probiotic development in lower respiratory tract.…”
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7295
Curcumin-enhanced NIR-II-responsive gold nanobipyramids for targeted HSP 90 inhibition
Published 2025-04-01“…Under the irradiation of NIR-II light, the obtained GNBs-Cur blocked the expression of HPS90 and inhibited related antiapoptotic pathways, thus enhancing the mild PTT of GNBs under 1064 nm laser irradiation. …”
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7296
APOE Christchurch enhances a disease-associated microglial response to plaque but suppresses response to tau pathology
Published 2025-01-01“…Results In 5xFAD mice, ApoeCh enhances a Disease-Associated Microglia (DAM) phenotype in microglia surrounding plaques, and reduces plaque load, dystrophic neurites, and plasma neurofilament light chain. By contrast, in PS19 mice, ApoeCh suppresses the microglial and astrocytic responses to tau-laden neurons and does not reduce tau accumulation or phosphorylation, but partially rescues tau-induced synaptic and myelin loss. …”
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7297
Multispecies pasture diet and cow breed affect the functional lipid profile of milk across lactation in a spring-calving dairy system
Published 2025-02-01“…Changes in total fatty acid (FA) and triglyceride carbon number profiles were determined by GC with a flame ionization detector, and those in polar lipids (PL) content by HPLC–evaporative light scattering–MS. Based on multivariate analysis, both diet (34.0% contribution) and breed (19.1% contribution) influenced milk FA on a yearly basis; however, in early lactation there were no differences in FA profile between the groups. …”
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7298
The impact of pre-transplant ventricular assist device support in pediatric patients with end-stage heart failure on the outcomes of heart transplantation—“a single center experien...
Published 2025-01-01“…IntroductionThe objective of this study was to examine the impact of ventricular assist device support as a bridge to heart transplantation in children with end-stage heart failure. In light of the limited availability of donor organs, particularly in Europe, the number of children requiring ventricular assist device support is rising at an unavoidable rate.MethodsWe performed a retrospective cohort study of patients who underwent a single and primary pediatric heart transplantation. …”
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7299
Revisiting Near-infrared Features of Kilonovae: The Importance of Gadolinium
Published 2025-01-01“…The observation of the kilonova AT2017gfo and investigations of its light curves and spectra confirmed that neutron star mergers are sites of r -process nucleosynthesis. …”
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7300
Microbial mechanisms underlying the reduction of N2O emissions from submerged plant covered system
Published 2025-09-01“…Further analysis of N2O metabolic rates from nitrification, denitrification, and abiotic processes under light and dark conditions confirmed that counter-diffusion of dissolved oxygen and nutrients in SP biofilms plays a key role in reducing denitrification-driven N2O emissions. …”
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