Small extracellular vesicles derived from sequential stimulation of canine adipose-derived mesenchymal stem cells enhance anti-inflammatory activity by Saranyou Oontawee, Parkpoom Siriarchavatana, Watchareewan Rodprasert, Irma Padeta, Yudith Violetta Pamulang, Poorichaya Somparn, Trairak Pisitkun, Boondarika Nambooppha, Nattawooti Sthitmatee, Daneeya Na Nan, Thanaphum Osathanon, Hiroshi Egusa, Chenphop Sawangmake

“…This study not only contributes to the enhancement of sEV production but also sheds light on their functional aspects for therapeutic interventions.…”
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Microbes and metabolites of a plant-parasite interaction: Deciphering the ecology of Tetrastigma host choice in the world’s largest parasitic flower, Rafflesia by Jeanmaire Molina, Roche C. de Guzman, Rinat Abzalimov, Wenkai Huang, Anusha Guruprasad, Ronniel Pedales, Adhityo Wicaksono, Destiny Davis, John Rey Callado, Hans Bänziger, Piyakaset Suksathan, William Eaton, Pride Yin, Marco Bürger, Mick Erickson, Stephen Jones, James Adams, Susan Pell

“…In this study, we integrated metagenomic data with metabolomic profiles to identify potential functional relationships between microbial communities and specific metabolites, shedding light on their ecological roles in Rafflesia's life cycle. …”
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Candidate SNP markers of changes in the expression levels of the human <i>SCN9A</i> gene as a hub gene for pain generation, perception, response and anesthesia by P. A. Dotsenko, K. A. Zolotareva, R. A. Ivanov, I. V. Chadaeva, N. L. Podkolodnyy, V. A. Ivanisenko, P. S. Demenkov, S. A. Lashin, M. P. Ponomarenko

“…This conclusion was consistent with literature data on a key role an efficient signal transduction from the peripheral to the central system from the peripheral to the central system for adjusting the human circadian rhythm through detection of a change from the dark of night to the light of day and for identification of the direction of the source of sound by auditory brainstem nuclei, for generating the response to cold stress and for physical coordination. 21 candidate SNP marker of significant SCN9A over- and underexpression. …”
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Remodeling of tumor microenvironments by EGFR tyrosine kinase inhibitors in EGFR-mutant non-small cell lung cancer by Soomin Kim, Jaemoon Koh, Tae Min Kim, Songji Oh, Soyeon Kim, Jeonghwan Youk, Miso Kim, Bhumsuk Keam, Yoon Kyung Jeon, Dong-Wan Kim, Dae Seog Heo

“…Two patients who showed the opposite pattern, transiting from C4 to C2, had durable responses to subsequent atezolizumab/bevacizumab/carboplatin/paclitaxel treatment. Our results shed light on the immunomodulatory effects of osimertinib treatment and suggest that co-targeting angiogenesis and anti-programmed death (ligand) 1 might be effective in EGFR-TKI-resistant non-small cell lung cancer.…”
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Predicting egg production rate and egg weight of broiler breeders based on machine learning and Shapley additive explanations by Hengyi Ji, Yidan Xu, Ganghui Teng

“…We systematically compared the performances of the following seven ML models in predicting egg production rate and egg weight: random forest (RF), multilayer perceptron (MLP), support vector regression (SVR), least squares support vector machine (LSSVM), k-nearest neighbors (kNN), XGBoost, and LightGBM. The results indicated that the XGBoost model demonstrated the best performance across all three datasets. …”
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Development and performance analysis of the 200 keV Cockcroft-Walton ion accelerator by H.R. Mirzaei, S.H. Sanaye, B. Yadollahzadeh, M. Shirshekan, M. Asl beigi, O. Hasanpour, Z. Riazi Mobaraki, F. Ghasemi, A. Mohammadi, M. Sadafi Biabli, A. Abbasi, M. Nazari, M. Dehghan, J. Rahighi, M. Jafarzadeh Khatibani, H. Ghods, A. Najafian

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Parameter influences of FTO/ZnO/Cu₂O photodetectors fabricated by electrodeposition and spray pyrolysis techniques by Muthiah N. Najah, Frida A. Rahmania, Integralita Cahyanti, Maulida Hesnaty, Siti Hajar Alias, Djoko Hartanto, Wahyu Prasetyo Utomo, Retno Sari, Hadi Nur

“…The characteristic of FTO/ZnO/Cu2O studied using XRD, SEM annexed with EDX, IV testing and visible light absorption spectroscopy to disclose its optoelectronic applications. …”
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Otodectes cynotis (Acari: Psoroptidae) infestations in Southern pudus (Pudu puda): In situ and ex situ data of an unexpected host-parasite record by Caroline Wilhelm, Edwin Kniha, Pamela Muñoz, Ángelo Espinoza, Laura Platner, Saskia Dreyer, Lisa Grund, Zoë Tess Lara Lindhorst, Ulrich Gärtner, Julia Walochnik, Anja Taubert, Dominik Fischer, Stephan Hering-Hagenbeck, Carlos Hermosilla, David Ebmer

“…During clinical work, two free-ranging pudus temporarily rehabilitated at the Centro de Rehabilitación de Fauna Silvestre (CEREFAS), Valdivia, Chile, were observed with low to moderate yellowish-brown secretions and encrustations inside the pinna and external auditory canal accompanied by an inflammatory Otitis externa. Analysis via light microscopy exhibited the presence of mange mites, which were identified as O. cynotis via morphological characteristics and molecular analysis. …”
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Al-Takrar Fii Daw'i Al-Dirasat Al-Uslubiyah Al-Haditsah by Aiyub Berdan

“…The research question is: what is the relationship between repetition and stylistic studies in light of modern stylistics? The objective is to uncover how repetition relates to stylistic studies within this modern context. …”
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Effects of moderate bandwidth on laser absorption and stimulated Raman sidescattering by Ning Kang, Yao Zhao, Anle Lei, Huiya Liu, Fujian Li, Guoxiao Xu, Honghai An, Jun Xiong, Ruirong Wang, Zhiyong Xie, Zhiheng Fang, Wei Wang, Lailin Ji, Shenlei Zhou, Guangyue Hu, Jiwei Li, Lifeng Wang, Yanqi Gao, Xiuguang Huang, Sizu Fu

“…Angular-resolved distributions of scattered light were diagnosed, which demonstrated that the laser absorption rate is enhanced by increasing the laser bandwidth. …”
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Segmentation of Dynamic Total-Body [18F]-FDG PET Images Using Unsupervised Clustering by Maria K. Jaakkola, Maria Rantala, Anna Jalo, Teemu Saari, Jaakko Hentilä, Jatta S. Helin, Tuuli A. Nissinen, Olli Eskola, Johan Rajander, Kirsi A. Virtanen, Jarna C. Hannukainen, Francisco López-Picón, Riku Klén

“…Thus, we conclude that there is a lack of accurate and computationally light general-purpose segmentation method that can analyse dynamic total-body PET images.…”
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Chemotherapy plus therapeutic plasmapheresis with 4% human albumin solution in multiple myeloma patients with acute kidney injury: a prospective, open-label, proof-of-concept study by Tianzhi Wu, Dandan Liu, Shangqin Liu, Hui Xiao, Bei Xiong, Yi Zhou, Yafen Xiong, Qin Cui, Jiang Wu, Minghui Liu, Hongli Liu, Yiming Li, Meixin Wang, Xueqin Bao, Ye Li, Fuling Zhou

“…In conclusion, in MM patients with AKI, plasma-free plasmapheresis with 4% human ALB solution and bortezomib-based chemotherapy effectively alleviated light chain damage to kidney function while improving patient quality of life.…”
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Performance of sewage sludge reuse in the manufacturing of fired bricks by K. Moulato, M. Ammari, L. Ben Allal

“…The bulk density analysis of brick sample 1 was 1.57 grams per cubic centimeter and classifies it as a light building material. Above 20 percent of samples substitution, their strength becomes less reliable, due to the large amount of organic matter that burns during firing which creates pores in the finished product.CONCLUSION: These results suggest that thermal processes limit the leaching of metals and are practically inaccessible to the ecosystem, so the brick cannot harm the environment. …”
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Adoption of Electric Vehicles and Forecasting Air Emissions in the Metropolitan Area of Mexico City by 2050 by Rodolfo Sosa Echeverría, Graciela Velasco Herrera, Pablo Sánchez Álvarez, Elías Granados Hernández, Gilberto Fuentes García, Victor Manuel Velasco Herrera, Rogelio González Oropeza, William Vicente Rodríguez, Jaime Gandarilla Ibarra, Rodrigo Rivera Rivera

“…We found that the most significant reductions in transportation emissions are observed in <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><mi>C</mi><msub><mi>O</mi><mn>2</mn></msub></mrow></semantics></math></inline-formula>, followed by <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><mi>N</mi><msub><mi>O</mi><mi>x</mi></msub></mrow></semantics></math></inline-formula>, volatile organic compound (VOC), and particulate matter, with light and heavy vehicles being the primary contributors to total emissions. …”
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Your period and your pregnancy, a cohort study of pregnant patients investigating the associations between menstruation and birth outcomes in Australia: study protocol by Miranda Davies-Tuck, Billie Bradford, Adrienne Gordon, Beverley Vollenhoven, Kirsten Rebecca Palmer, Kirstin Tindal, Caroline E Gargett, Fiona Cousins, Stacey Ellery

“…Here, the endometrial environment may shed light on factors that influence placental development and the trajectory of a pregnancy. …”
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Omics-Based Comparison of Fungal Virulence Genes, Biosynthetic Gene Clusters, and Small Molecules in <i>Penicillium expansum</i> and <i>Penicillium chrysogenum</i> by Holly P. Bartholomew, Christopher Gottschalk, Bret Cooper, Michael R. Bukowski, Ronghui Yang, Verneta L. Gaskins, Dianiris Luciano-Rosario, Jorge M. Fonseca, Wayne M. Jurick

“…While these two fungi have been investigated individually, a recent discovery revealed that <i>P. chrysogenum</i> can block <i>P. expansum-</i>mediated decay of apple fruit. To shed light on this observation, we conducted a comparative genomic, transcriptomic, and metabolomic study of two <i>P. chrysogenum</i> (404 and 413) and two <i>P. expansum</i> (Pe21 and R19) isolates. …”
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Oxidative potential determines the oxidative stress and ferroptotic toxicity of airborne particulate matter on pulmonary epithelial cells by Bingxue Nie, Daoqiang Zhang, Xin Liu, Chengying Lei, Zhiruo Li, Nan Zhang, Shuping Zhang, Yiju Wei, Jie Zhang

“…This study provides additional insights into the structure-activity relationship for PM’s toxicity. It also sheds light on further investigations on the detoxication of PM.…”
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Challenges faced by women oncologists in Africa: a mixed methods study by Doreen Ramogola-Masire, Reshma Jagsi, Matthew Jalink, Verna Vanderpuye, Nwamaka Lasebikan, Miriam Mutebi, Nazik Hammad, Susan Msadabwe, Laura Carson, Dorothy Chilambe Lombe, Zainab Doleeb, Haimanot Kasahun Alemu, Nesrine Chraiet, Naa Adorkor Aryeetey, Zainab Mohamed, Nazima Jaffer Dharsee, Sitna Mwanzi, Khadija Warfa, Emmanuella Nwachukwu, Edom Seife Woldetsadik, Hirondina Vaz Borges Spencer

“…A systems-level dialogue could bring light to these challenges and foster tangible action and policy-level changes.…”
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Lattice-based interpenetrating phase composite metamaterial fabricated with hybrid material extrusion process for tunable mechanical properties by Ritik Raj, Jung-Ting Tsai, Mayur Jiyalal Prajapati, Jeng-Ywan Jeng

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Investigation of the Ultrasonic Treatment-Assisted Soaking Process of Different Red Kidney Beans and Compositional Analysis of the Soaking Water by NIR Spectroscopy by Matyas Lukacs, Tamás Somogyi, Barasa Mercy Mukite, Flóra Vitális, Zoltan Kovacs, Ágnes Rédey, Tamás Stefaniga, Tamás Zsom, Gabriella Kiskó, Viktória Zsom-Muha

“…The PLSR- and SVR-based modelling for dry matter content and light color parameters demonstrated robust model fits with cross and test set-validated R² values (>0.95), suggesting that these techniques can effectively capture the chemical information of the samples.…”
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