ACOX1 activates autophagy via the ROS/mTOR pathway to suppress proliferation and migration of colorectal cancer by Bo Shi, Junjie Chen, Haoran Guo, Xinyu Shi, Qingliang Tai, Guoliang Chen, Huihui Yao, Xiuwei Mi, Runze Zhong, Yang Lu, Yiyuan Zhao, Liang Sun, Diyuan Zhou, Yizhou Yao, Songbing He

“…This study aims to elucidate the impact of ACOX1 in CRC, shedding light on its potential as a therapeutic target. Through analysis of the GEO dataset, it was found that ACOX1 is significantly downregulated in colorectal cancer (CRC), and this lower expression level is associated with a worse prognosis. …”
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Alteration in the Cytokine Secretion of Bone Marrow Stromal Cells from Patients with Chronic Myelomonocytic Leukemia Contribute to Impaired Hematopoietic Supportive Activity by Hui Shi, Yingshao Wang, Rong Li, Wen Xing, Feng-Chun Yang, Jie Bai, Yuan Zhou

“…These results suggested that BMSCs may contribute to the pathogenesis of CMML by altering their cytokine secretion, which will shed light on the further investigation to develop novel therapeutic strategies for CMML patients.…”
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Efficacy of phototherapy to treat facial ageing when using a red versus an amber LED: a protocol for a randomised controlled trial by Lidiane Rocha Mota, Christiane Pavani, Lara Jansiski Motta, Anna Carolina Ratto Tempestini Horliana, Ivone da Silva Duarte, Daniela de Fátima Teixeira da Silva

“…Nowadays, there are numerous treatments for ageing skin, and one of them is with the use of phototherapy, which uses light-emitting diodes (LEDs). The objective of this study will be to evaluate the percentages of reduction in the volume of periocular wrinkles when treated with red and amber LEDs.Methods and analysis All of the participants will receive photobiomodulation to treat their periocular wrinkles. …”
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Nutritional content and healthiness in sweet and salty snacks and beverages popular in South Korea and the United States assessed by nutrition labels: a cross-sectional comparative... by Bo Jeong Gong, Segovia Lucas, Diewo Camara, Pauline E. Jolly, Chandrika Piyathilake, Taisun Hyun

“…The FoPNL system was used to assess the healthiness of the products, which included multiple traffic light labels, a Health Star Rating, and a Nutri-Score. …”
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High-Fidelity Depth Map Reconstruction System With RGB-Guided Super Resolution CNN and Cross-Calibrated Chaos LiDAR by Yu-Chun Ding, Chia-Yu Chang, Pei-Rong Li, Chao-Tsung Huang, Yung-Chen Lin, Tsung Chen, Wei-Lun Lin, Cheng-Ting Lee, Fan-Yi Lin, Yuan-Hao Huang

“…However, the performance of current 3D recording devices is limited in several scenarios, such as dim light environments, long-distance measurements, and large-scale objects. …”
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Explainable AutoML models for predicting the strength of high-performance concrete using Optuna, SHAP and ensemble learning by Muhammad Salman Khan, Tianbo Peng, Tianbo Peng, Muhammad Adeel Khan, Asad Khan, Mahmood Ahmad, Mahmood Ahmad, Kamran Aziz, Mohanad Muayad Sabri Sabri, N. S. Abd EL-Gawaad

“…This study introduces four explainable Automated Machine Learning (AutoML) models that integrate Optuna for hyperparameter optimization, SHapley Additive exPlanations (SHAP) for interpretability, and ensemble learning algorithms such as Random Forest (RF), Extreme Gradient Boosting (XGB), Light Gradient Boosting Machine (LGB), and Categorical Gradient Boosting (CB). …”
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Prevalence and Determinants of Geohelminthiasis among School-Age Children in Jimma City, Ethiopia by Ahmed Zeynudin, Teshome Degefa, Sultan Suleman, Abdulhakim Abamecha, Zuber Hajikelil, Andreas Wieser

“…Most (86.6%) of the STH-positive SAC had a single infection and a light infection intensity (88.2%), with a mean intensity of 367.4 eggs per gram. …”
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Time Perception Test in IntelliCage System for Preclinical Study: Linking Depression and Serotonergic Modulation by Olga Sysoeva, Rauf Akhmirov, Maria Zaichenko, Ivan Lazarenko, Anastasiya Rebik, Nadezhda Broshevitskaja, Inna Midzyanovskaya, Kirill Smirnov

“…<b>Methods:</b> Wistar male rats (<i>n</i> = 25, five groups of 5–8) were trained in the IntelliCage to discriminate between short (1 s) and long (4 s) LED light stimuli by nose poking at the corresponding (left/right) side of the IntelliCage chamber to obtain a drink. …”
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Vertical flow immunoassay for multiplex mycotoxins based on photonic nitrocellulose and SERS nanotags by Ruipeng Chen, Jingfang Hu, Hui Wang, Cheng Li, Haiqi Kang, Yuxuan Chen, Liang Yang, Xiangfang Tang, Benhai Xiong, Xiangwei Zhao

“…In the immunoassay, because of the slow-photon effect of the PNC substrate, which facilitates the light coupling with SERS nanotags, the SERS signal was highly enhanced. …”
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Land use land cover changes from 2003 to 2023 using Remote Sensing and GIS techniques in Niamotpur Upazila with a predictive study for the next decade by Nazmul Hossain, Jannatul Adnan, Tasmia Jahin Mim, Ayesha Binte Zohir, Iftakhar Ahmad, Ahmadullah Zaman, Mehedi Hasan, Noor Hossain

“…From 2003 to 2023 bare soil consistently decreased, while deep vegetation significantly increased, indicating improved land health. Urban areas and light vegetation peaked in 2013 but declined by 2023. …”
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Protective effects and antioxidant mechanisms of lactobacillus combined with carnosine on the stomach and small intestine by Jian Qin, Ziyi Luo, Xu Yang, Yunqing Zhang, Huiying Li, Conghui Wang, Zhiqiang Zou, Yue Ma, Jing Ma, Daoyou Yue, Dipeng Zhao, Sen Qin, Rong Du

“…Additionally, this combined treatment increased the activity of antioxidant enzymes and up-regulated the expression of antioxidant genes in the Nrf2 signaling pathway in stress mice. Our study sheds light on the synergetic and complementary roles of LAB and CAR in maintaining the structural and functional integrity of stomach and small intestine, offering clues for understanding the regulation of antioxidant enzyme genes through the Nrf2 pathway as a potential mechanism.…”
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Exploring timely and safe discharge from ICU: a comparative study of machine learning predictions and clinical practices by Chao Ping Wu, Rachel Benish Shirley, Alex Milinovich, Kaiyin Liu, Eduardo Mireles-Cabodevila, Hassan Khouli, Abhijit Duggal, Anirban Bhattacharyya

“…Result In the 2015-to-2019 cohort, the study included 17,852 unique ICU admissions. The LightGBM model outperformed other algorithms, achieving a AUROC of 0.91 (95%CI 0.9–0.91) and performance was held in the 2020 validation cohort (n = 509) with an AUROC of 0.85 (95%CI 0.84–0.85). …”
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Empowering wastewater treatment with step scheme heterojunction ternary nanocomposites for photocatalytic degradation of nitrophenol by Zhu Liu, Mah Roosh, Ming Lu, Aqsa Arshad, Wenqi Xian, Yuqiu Shen, Guocong Liu, Ali Bahadur, Shahid Iqbal, Sajid Mahmood, Khalid M. Alotaibi

“…Our results demonstrated that the Bi2O3/CdS heterojunction achieved an 86% degradation rate of 4-nitrophenol, while the MoS2/Bi2O3/CdS composite exhibited exceptional photocatalytic performance, achieving nearly complete degradation (99%) within 120 min under visible light irradiation. Most importantly the improved photocatalytic activity of MoS2/Bi2O3/CdS heterojunction originated from the release of internal electric field in S-scheme heterojunction. …”
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Possible Superconductivity Transition in Nitrogen‐Doped Lutetium Hydride Observed at Megabar Pressure by Xingbin Zhao, Yu Huang, Shuailing Ma, Hao Song, Yanwei Cao, Hao Jiang, Yanping Huang, Tian Cui

“…This work is expected to shed some light on the controversy surrounding superconductivity in the nitrogen‐doped lutetium hydride system.…”
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Investigating the Effect of Bamboo Fibers on The Engineering Properties of Laterite Soils in Road Construction. by Kiiza, Obed

“…Maximum dry density (MDD) increases with fibre contents at 0 - 0.75% from 1.923 – 2.207g/cm3 and 1.980 – 2.092g/cm3 for heavy and light compaction respectively and decreases with further fibre increment while the optimum moisture content (OMC) decreased continually for all compaction efforts with higher fibre contents from 15.7 - 10.2% and 12.6 – 9.8% for (0 – 1.0% fibre) respectively. …”
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Factors Affecting Teachers in Implementing the Thematic Curriculum in Primary Schools in Uganda: A Case Study of Butogota Primary School Kanungu District. by Twinomujuni, Dorothy

“…The study's findings shed light on the multifaceted reasons behind teacher resistance to adopting thematic curriculum approaches. …”
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Mineralogy, alteration, fluid inclusions microthermometry and genesis of the Cu-Au Kalateh Dasht deposit, south of Shahrood, NE Iran by Mohadeseh Eskandari, Fardin Mousivand, Maryam Sheibi, Bernd Lehmann

“…The presence of light-colored sphalerite, which indicates a low iron content, serves as an additional indicator of epithermal systems with moderate sulfidation. …”
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Characteristics of Soil Profile Greenhouse Gas Concentrations and Fluxes of Alpine Grassland as Affected by Livestock Grazing by Mingyuan Yin, Xiaopeng Gao, Yanyan Li, Yufeng Wu, Wennong Kuang, Fanjiang Zeng

“…In this study, a field experiment was conducted in 2017 and 2018 to evaluate the influences of three grazing intensities (none, light, heavy) on both soil surface and subsurface (0–60 cm) GHG fluxes estimated using chamber-based and concentration gradient-based methods, respectively. …”
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Effectiveness of an E-Nose Based on Metal Oxide Semiconductor Sensors for Coffee Quality Assessment by Yhan S. Mutz, Samara Mafra Maroum, Leticia L. G. Tessaro, Natália de Oliveira Souza, Mikaela Martins de Bem, Loyane Silvestre Alves, Luisa Pereira Figueiredo, Denes K. A. do Rosario, Patricia C. Bernardes, Cleiton Antônio Nunes

“…The tasks were (i) the separation of <i>Coffea arabica</i> and <i>Coffea canephora</i> species, (ii) the distinction between roasting profiles (light, medium, and dark), and (iii) the separation of expired and non-expired coffees. …”
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Assessing the Impact of Binary Systems on Microlensing Using SPISEA and PopSyCLE Population Simulations by Natasha S. Abrams, Jessica R. Lu, Casey Y. Lam, Michael S. Medford, Matthew W. Hosek Jr., Sam Rose

“…The majority of these events have photometric light curves that appear single and are fit well by a single-lens, single-source model. …”
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