Unveiling the omics tapestry of B-acute lymphoblastic leukemia: bridging genomics, metabolomics, and immunomics by Yin Le, Shicong Zhu, Hongling Peng, Zhihua Wang

“…Abstract Acute B-lymphoblastic leukemia (B-ALL) is a highly heterogeneous hematologic malignancy, characterized by significant molecular differences among patients as the disease progresses. …”
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IgE Plasma Cell Leukemia Harboring t(11;14) and 1q Amplification by Wataru Nakahara, Takahito Ogawa, Hitomi Matsunaga, Yuki Iwasa, Momoka Horita, Mako Ikeda, Mizuki Asako, Sadaharu Iio, Yuki Iwama, Kazumasa Oka, Shuji Ueda

“…Here, we report a case of IgE primary plasma cell leukemia with extramedullary lesions of the liver, stomach, and lymph nodes. …”
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Association of killer immunoglobulin-like receptor genotypes and haplotypes with acute lymphoblastic leukemia risk by Jameel Al-Tamimi, Suliman Alomar, Ali Aljuaimlani, Lamjed Mansour

“…This study aimed to investigate the relationships between KIR genotypes and haplotypes with acute lymphoblastic leukemia (ALL) in Saudi patients. Methods A total of 259 Saudi subjects including 145 cases of acute lymphoblastic leukemia (ALL) and 114 healthy controls living in Riyadh were genotyped for 16 KIR genes and the two HLA-C1 and -C2 allotypes using PCR-SSP genotyping method. …”
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Prolonged Pediatric Extracorporeal Membrane Oxygenation Support with Cardiopulmonary Failure in Juvenile Myelomonocytic Leukemia by Maris Bartkevics, Bert Hennig, Tayfun Gungor, Roland Ammann, Alexander Kadner

“…We report a case of a child survival after extracorporeal membrane oxygenation (ECMO) support of 25 days for cardiopulmonary failure and septic shock in the context of juvenile myelomonocytic leukemia (JMML). ECMO support is still a matter of debate for the management of septic patients with malignancy. …”
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Chronic Myeloid Leukemia Relapsing 25 Years after Allogenic Stem Cell Transplantation by Håkon Reikvam, Jørn Skavland, Stein-Erik Gullaksen, Randi Hovland, Tobias Gedde-Dahl, Øystein Bruserud, Bjørn Tore Gjertsen

“…Chronic myeloid leukemia (CML) is a myeloproliferative disorder in which neoplastic cells exhibit the Philadelphia chromosome and the related oncoprotein BCR-ABL1. …”
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Critically ill adult patients with acute leukemia: a systematic review and meta-analysis by Dara Chean, David Luque-Paz, Daniele Poole, Sofiane Fodil, Etienne Lengliné, Thibault Dupont, Achille Kouatchet, Michael Darmon, Élie Azoulay

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Permanent Sensorineural Deafness in a Patient with Chronic Myelogenous Leukemia Secondary to Intracranial Hemorrhage by Sakshi Kapur, Michael Wax, Levin Miles, Adnan Hussain

“…The initial impression was chronic myelogenous leukemia with hyperleukocytosis, and patient was started on hydration, hydroxyurea, and allopurinol. …”
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CD9 in acute myeloid leukemia: Prognostic role and usefulness to target leukemic stem cells by Lucas Touzet, Florent Dumezy, Christophe Roumier, Céline Berthon, Claire Bories, Bruno Quesnel, Claude Preudhomme, Thomas Boyer

Subjects: “…acute myeloid leukemia…”
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Hemophagocytic lymphohistiocytosis secondary to refractory acute myeloid leukemia resolved after second line treatment with azacitidine plus venetoclax by Claudio Fozza

Subjects: “…acute myeloid leukemia…”
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How to use monoclonal antibody-based therapy in ALL by Erica Brivio, Sujith Samarasinghe

Subjects: “…Pediatric leukemia…”
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Nilotinib-Induced Dystonia and Cognitive Deficits in a Neurologically Normal Patient with Chronic Myeloid Leukemia by Justine Chan, Paarth Shah, Guillermo Moguel-Cobos

“…Nilotinib is a tyrosine kinase inhibitor used to treat patients with chronic myeloid leukemia (CML). This agent is also being studied in neurodegenerative disorders including Parkinson disease. …”
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Wickerhamomyces anomalous: A Rare Cause of Fungemia Causing Febrile Neutropenia in Acute Lymphoblastic Leukemia by Vibha Mehta, Aroop Mohanty, Suneeta Meena, J. S. Rahul, Nath Uttam Kumar, Debranjani Chattopadhyay, Anamika Bakliwal, Ranjana Choudhary, Pratima Gupta

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Osteoblastic and Vascular Endothelial Niches, Their Control on Normal Hematopoietic Stem Cells, and Their Consequences on the Development of Leukemia by Bella S. Guerrouahen, Ibrahim Al-Hijji, Arash Rafii Tabrizi

“…And finally, we will review some data on the development of acute myeloid leukemia from a subpopulation called leukemia-initiating cells (LIC), and we will discuss on the emerging evidences supporting the influence of the microenvironment on chemotherapy resistance.…”
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A Unique Case of Relapsed B-Acute Lymphoblastic Leukemia/Lymphoma as an Isolated Omental Mass by Kanchan Kantekure, Furha Cossor, Kenneth B. Miller, Monika E. Pilichowska

“…B-acute lymphoblastic leukemia/lymphoma (B-ALL) is a neoplasm of precursor cells committed to the B-cell lineage. …”
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ALL-Net: integrating CNN and explainable-AI for enhanced diagnosis and interpretation of acute lymphoblastic leukemia by Abhiram Thiriveedhi, Swetha Ghanta, Sujit Biswas, Ashok K. Pradhan

Subjects: “…Acute lymphoblastic leukemia…”
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Unusual Presentation with Orbital Mass in a Child with Precursor B-Cell Acute Lymphoblastic Leukemia by Lalita Sathitsamitphong, Rungrote Natesirinilkul, Worawut Choeyprasert, Pimlak Charoenkwan

“…Orbital involvement is one of the extramedullary manifestations in acute leukemia. It is common in acute myeloid leukemia, but rare in acute lymphoblastic leukemia (ALL). …”
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An unveiling case of Nocardia pansinusitis in a patient with chronic lymphocytic leukemia: a case report by Maedeh Najafizadeh, Fatemeh Kourkinejad Gharaei, Reza Manouchehri Ardekani, Mahdi Rafiyan

“…Case presentation In this case report, we present, for the first time, a 55-year-old Iranian male patient diagnosed with chronic lymphocytic leukemia who was receiving chemotherapeutic drugs and developed a fever. …”
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A young adult patient with Philadelphia positive acute lymphoblastic leukemia presenting with extreme hyperleukocytosis by Gulten Tikit, Elif Yucesu, Aliye Serpil Sarıfakıoglu, Imdat Dilek, Sule Mine Bakanay

Subjects: “…acute lymphoblastic leukemia (ALL)…”
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MYST3/CREBBP Rearranged Acute Myeloid Leukemia after Adjuvant Chemotherapy for Breast Cancer by Arjun Gupta, Mrinal M. Patnaik, Harris V. Naina

“…Although rare, clinicians and patients must be aware that therapy related malignancies, specifically acute myeloid leukemia (AML), can occur as a complication of adjuvant chemotherapy for breast cancer. …”
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Protein Kinase CK2: A Targetable BCR-ABL Partner in Philadelphia Positive Leukemias by Alessandro Morotti, Giovanna Carrà, Cristina Panuzzo, Sabrina Crivellaro, Riccardo Taulli, Angelo Guerrasio, Giuseppe Saglio

“…BCR-ABL-mediated leukemias, either Chronic Myeloid Leukemia (CML) or Philadelphia positive Acute Lymphoblastic Leukemia (ALL), are the paradigm of targeted molecular therapy of cancer due to the impressive clinical responses obtained with BCR-ABL specific tyrosine kinase inhibitors (TKIs). …”
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