An Acute Transverse Myelitis Attack after Total Body Irradiation: A Rare Case by Muzaffer Keklik, Leylagul Kaynar, Afra Yildirim, Serdar Sivgin, Celalettin Eroglu, Serife Cingoz, Cigdem Pala, Bulent Eser, Mustafa Cetin, Ali Unal

“…In this paper, we presented an ATM attack developed after TBI in a patient with acute lymphoblastic leukemia (ALL) as it is a rarely seen case.…”
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Molecular dynamics simulations reveal key roles of the LIF receptor in the assembly of human LIF signaling complex by Bo Gao, Hanrui Liu, Mengkai Zhu, Shun Zhang, Meiniang Wang, Yijun Ruan, Yue Zheng

“…Leukemia inhibitory factor (LIF) is a critical cytokine involved in various biological processes, including stem cell self-renewal, inflammation, and cancer progression. …”
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Sintilimab for treating progressive multifocal leukoencephalopathy caused by human polyomavirus 2 virus infection following allogeneic hematopoietic cell transplantation: a case re... by Xuelian Jin, Xushu Zhong, Qinyu Liu, Xinchuan Chen

“…Here, we report a case of successful treatment of PML with sintilimab following allogeneic hematopoietic stem cell transplantation.Case presentation: A 35-year-old woman with high-risk acute myeloid leukemia underwent allogeneic hematopoietic stem cell transplantation after induced remission and developed PML 12 months after transplantation. …”
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TLR2 Derangements Likely Play a Significant Role in the Inflammatory Response and Thrombosis in Patients with Ph(−) Classical Myeloproliferative Neoplasm by Jen Chin Wang, Guanfang Shi, Chi Chen, Ching Wong, Vladimir Gotlieb, Gardith Joseph, Kiron V Nair, Lakshmi Boyapati, Enayati Ladan, James T. Symanowski, Lishi Sun

“…These data suggests that MPNs initially involve TLR2, with minor contributions from TLR4, and with S100A9, leading to ROS formation, JAK2 mutation, and progression to MF or leukemia. Furthermore, patients with JAK2 mutations or leukocytosis exhibited higher TLR2 expression. …”
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Biphasic Chromatin Structure and FISH Signals Reflect Intranuclear Order by Jyoti P. Chaudhuri, Eva Kasprzycki, Mathew Battaglia, John R. McGill, Anton Brøgger, Joachim-U. Walther, Albrecht Reith

“…Results and Aignificance: A small number of cells (up to about 5%), more frequent in leukemia cases, showed the twin features: (1) nuclei with biphasic chromatin, one part decondensed and the other condensed; and (2) homologous FISH signals distributed equitably in those two regions. …”
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Luteolin ameliorates rat model of metabolic syndrome-induced cardiac injury by apoptosis suppression and autophagy promotion via NR4A2/p53 regulation by Xiyan Dai, Bo Liang, Yaolin Sun

“…Cardiac NR4A2 and p53, as well as apoptotic (B-cell leukemia/lymphoma 2 [BCL-2], Caspase [CASP]-3, and CASP-9) and autophagic mediators (Sequestosome-1/p62, Microtubule-associated protein 1 A/1B-light chain 3 [LC3], and Beclin-1) were measured by RT-qPCR and ELISA. …”
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Miliary Tuberculosis in Immunocompromised Patient Induced by Imatinib and Steroid by Randa Fermada, Fauzar Fauzar, Roza Kurniati, Irza Wahid

“…Due to chronic myelogenous leukemia and autoimmune hemolytic anemia, the patient is known under imatinib and steroid therapy.  …”
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Prevalence of sexual dysfunction in HTLV-1 patients without spastic paraparesis and the association with psychiatric symptoms by Maedeh Kamrani, Narges Niazi Rad, Fariba Zemorshidi, Majid Khadem-Rezaiyan

“…Patients with spastic paraparesis, leukemia, and uveitis, and those with an expanded disability status scale (EDSS) score higher than 2 were excluded. …”
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Dendritic cell maturation, but not type I interferon exposure, restricts infection by HTLV-1, and viral transmission to T-cells. by Gergès Rizkallah, Sandrine Alais, Nicolas Futsch, Yuetsu Tanaka, Chloé Journo, Renaud Mahieux, Hélène Dutartre

“…Human T lymphotropic Virus type 1 (HTLV-1) is the etiological agent of Adult T cell Leukemia/Lymphoma (ATLL) and HTLV-1-Associated Myelopathy/Tropical Spastic Paraparesis (HAM/TSP). …”
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Dextran-Polyacrylamide as Matrices for Creation of Anticancer Nanocomposite by G. Telegeev, N. Kutsevol, V. Chumachenko, A. Naumenko, P. Telegeeva, S. Filipchenko, Yu. Harahuts

“…The polymer nanoparticles loaded with cisplatin at different concentrations from 0.1 to 10 μg/mL yielded dose-dependent decrease in viability of chronic myelogenous leukemia and histiocytic lymphoma cells. The lowest percentage of viable cells was observed for lymphoma cells (22%). …”
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A Rare Presentation of Lymphoma of the Cervix with Cross-Sectional Imaging Correlation by Brinda Rao Korivi, Corey T. Jensen, Madhavi Patnana, Keyur P. Patel, Tharakeswara K. Bathala

“…A 43-year-old asymptomatic female with a history of dual hit blastic B-cell lymphoma/leukemia in complete remission presented with an incidental cervical mass, which was initially felt to represent a cervical fibroid on computed tomography (CT). …”
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Translocation (6;15)(q12;q15): A Novel Mutation in a Patient with Therapy-Related Myelodysplastic Syndrome by Saba F. Ali, Rebecca J. Sonu, Denis M. Dwyre, Brian A. Jonas, Hooman H. Rashidi

“…We present a unique case of a patient who initially presented with acute myeloid leukemia (AML) with a normal karyotype and FLT3-ITD and NPM1 mutations. …”
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The AST/ALT (De Ritis) ratio as a significant prognostic factor in myelodysplastic syndrome by Ying Chen, Yue Wu, Ting Chen, Duobing Zou, Cong Shi, Ningning Wu, Lixia Sheng, Guifang Ouyang, Qitian Mu

“…The clinical, laboratory, and follow-up data of patients with MDS were collected, while the relationship between AST/ALT ratio and overall survival (OS) and leukemia-free survival (LFS) were also analyzed. Results: The results showed that higher AST/ALT ratio was associated with higher age, β2-microglobulin level, and number of co-mutations (>4). …”
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Evaluation of the practical application of the category-imbalanced myeloid cell classification model. by Zhigang Hu, Aoru Ge, Xinzheng Wang, Cuisi Ou, Shen Wang, Junwen Wang

“…The incidence of acute myeloid leukemia (AML) is increasing annually, and timely diagnostic and treatments can substantially improve patient survival rates. …”
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Biochemical characterization of the human ubiquitous glucose‐6‐phosphatase in neutrophil granulocytes by Zsigmond Lédeczi, Klaudia Németh, Tamás Kardon

“…Using the HL‐60 promyelocytic leukemia cell line as an in vitro model system for myeloid differentiation, we found no significant differences in enzyme expression and phosphatase activity latency between undifferentiated and differentiated cells. …”
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Optimal Molecular Methods in Detecting p190BCR-ABL Fusion Variants in Hematologic Malignancies: A Case Report and Review of the Literature by Rebecca J. Sonu, Brian A. Jonas, Denis M. Dwyre, Jeffrey P. Gregg, Hooman H. Rashidi

“…Patients with BCR-ABL1 positive hematologic malignancies and Philadelphia-like B-lymphoblastic leukemia (B-ALL) are potential candidates for targeted therapy with tyrosine kinase inhibitors (TKI). …”
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Colonization of a Central Venous Catheter by the Hyaline Fungus Fusarium solani Species Complex: A Case Report and SEM Imaging by Alberto Colombo, Giuseppe Maccari, Terenzio Congiu, Petra Basso, Andreina Baj, Antonio Toniolo

“…The case of a 13-year-old boy under treatment for acute lymphoblastic leukemia is presented. The boy was readmitted to the Pediatric Ward for intermittent fever of unknown origin. …”
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β2microglobulin levels, clinical and sociodemographic variables in patients with recently diagnosed chronic lymphoproliferative syndrome by Pedro Javier Sánchez Sánchez, Julio Dámaso Fernández Águila, Pedro Sánchez Frenes, María de Jesús Sánchez Bouza, Karelys Díaz Alfonso

“…The series was made up of all adult patients (universe 50) recently diagnosed (without starting specific antitumor therapy) of multiple myeloma, chronic lymphoid leukemia, non-Hodgkin lymphoma and Hodgkin lymphoma, admitted to the Hematology Service of the Dr. …”
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Targeting ceramide transfer protein sensitizes AML to FLT3 inhibitors via a GRP78-ATF6-CHOP axis by Xiaofan Sun, Yue Li, Juan Du, Fangshu Liu, Caiping Wu, Weihao Xiao, Guopan Yu, Xiaowei Chen, Robert Peter Gale, Hui Zeng

“…Combining CERT inhibitor with FLT3 inhibitor exhibits synergistic effects on FLT3-ITD mutated acute myeloid leukemia (AML) cells. Additionally, co-treatment of HPA-12 and Crenolanib is effective in FLT3-ITD+ and FLT3-TKD+ AML patients. …”
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Rural-Urban Disparity in Premature Cancer Mortality in Young People Aged 15–44 Years in China, 2004–2021 by Chunrong Chen, Xing Xing, Shaojie Li, Bo Qu, Chunyu Liu, He Zhu, He Zhu

“…The five leading types of cancer deaths consistently remained liver, lung, leukemia, stomach, and other cancers in both rural and urban areas after 2013.ConclusionOur findings indicate that there were rural-urban disparities in cancer mortality in young people, which showed a different pattern compared to other age groups. …”
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