Editorial for the Special Issue ‘Molecular Mechanisms of Leukemia’ by Jungeun An, Myunggon Ko

“…Leukemia encompasses a diverse and intricate group of hematological malignancies that arise from hematopoietic stem and progenitors (HSPCs) in the bone marrow [...]…”
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Chronic Eosinophilic Leukemia Presenting as Cardiac Failure by Nii Boi-Doku Pepra-Ameyaw, William Kwasi Ghunney, Eugene Baafi Ampofo, Edeghonghon Olayemi

“…Chronic eosinophilic leukemia (CEL) is a rare chronic myeloproliferative disorder characterized by sustained eosinophilia. …”
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Acute Myeloid Leukemia Presenting with Pulmonary Tuberculosis by Merlin Thomas, Mushtak AlGherbawe

“…Bone marrow aspiration revealed acute myeloid leukemia. Thereafter the patient received induction chemotherapy and continued antituberculous treatment. …”
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CHRONIC MIELOMONOSITIC LEUKEMIA PADA USIA MUDA by Rangga Lunesia, Irza Wahid

“…Chronic Mielomonositic Leukemia (CMML) adalah keganasan heterogen yang ditandai dengan monositosis di darah perifer (>1x109/L), terdapat kelainan mielodisplastik dan mieloproliferatif di sumsum tulang, dan memiliki kecendrungan untuk bertransformasi menjadi leukemia myeloid akut. …”
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BLINATUMOMAB IN THE THERAPY OF ACUTE B-LYMPHOID LEUKEMIA by Ugo Testa, Elvira Pelosi, Germana Castelli, Patrizia Chiusolo

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Coexistence of Chronic Lymphocytic Leukemia and Myeloproliferative Neoplasm by Patrycja Zielinska, Miroslaw Markiewicz, Monika Dzierzak-Mietla, Anna Koclega, Grzegorz Helbig, Slawomira Kyrcz-Krzemien

“…Chronic lymphocytic leukemia (CLL) is the most common adult leukemia in the Western world. …”
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Molecular Targets for the Treatment of Juvenile Myelomonocytic Leukemia by Xiaoling Liu, Himalee Sabnis, Kevin D. Bunting, Cheng-Kui Qu

“…Significant advances in our understanding of the genetic defects and the pathogenesis of juvenile myelomonocytic leukemia (JMML) have been achieved in the last several years. …”
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Laparoscopic Splenectomy for Hairy Cell Leukemia in Pregnancy by Beni Adegoke Adeniji, Moses Fallas, Marc Incerpi, Solomon Hamburg, Robert Katz, Dotun Ogunyemi

“…We present a successful case of laparoscopic splenectomy for a massively enlarged spleen at 25 weeks of gestation for hairy cell leukemia in pregnancy in a woman with initial hemoglobin of 4.3 gm/dl and platelet count of 18,000/mm3. …”
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Myelodysplasia and Mast Cell Leukemia with t(9;22) by Kathryn J. Lago, Matthew P. Shupe, William N. Hannah, Gopalrao V. N. Velagaleti, Christina Mendiola, Veronica Ortega, Brian R. Haney

“…Introduction. Mast cell leukemia (MCL) is a rare variant of systemic mastocytosis. …”
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Biphenotypic Acute Leukemia versus Myeloid Antigen-Positive ALL: Clinical Relevance of WHO Criteria for Mixed Phenotype Acute Leukemia by William A. Hammond, Pooja Advani, Rhett P. Ketterling, Daniel Van Dyke, James M. Foran, Liuyan Jiang

“…Updated WHO criteria define mixed phenotype acute leukemia (MPAL) with more stringent diagnostic criteria than the formerly described entity biphenotypic acute leukemia (BAL). …”
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Cardiopulmonary Failure Requiring ECMO Bypass Resulting from Leukemia Cell Lysis in a Patient with Childhood Acute Myelomonocytic Leukemia by Michael Huang, Erin Owen, Scott Myers, Ashok Raj

“…Pulmonary leukostasis and systemic inflammatory response syndrome (SIRS) following leukemia cell lysis are the likely etiologies. Observation. …”
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Early T-Cell Precursor Leukemia Has a Higher Risk of Induction-Related Infection among T-Cell Acute Lymphoblastic Leukemia in Adult by Kangyu Huang, Min Dai, Qiuli Li, Nannan Liu, Dainan Lin, Qiang Wang, Xuan Zhou, Zhixiang Wang, Ya Gao, Hua Jin, Xiaoli Liu, Qifa Liu, Hongsheng Zhou

“…Infections are an important cause of morbidity and mortality for acute lymphoblastic leukemia (ALL). However, the reports regarding risk factors of induction-related infection are roughly unknown/limited in adult T-ALL during induction chemotherapy. …”
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Leukemia Limfositik Kronik pada Limfoma Non Hodgkin by Rahmi Sahreni, Irza Wahid

“…Leukemia Limfositik Kronik (LLK) adalah suatu keganasan hematologik yang ditandai oleh proliferasi klonal dan penumpukan limfosit B neoplastik dalam darah. …”
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Pneumatosis Intestinalis in a Patient with Acute Promyelocytic Leukemia by Abhishek Mangaonkar, Joshua Mansour, Ryan Keen, Tarun Kukkadapu, Rohini Chintalapally, Vamsi Kota

“…We describe a case of a 33-year-old woman with acute promyelocytic leukemia who developed nausea and nonbloody diarrhea. …”
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Translating Unconventional T Cells and Their Roles in Leukemia Antitumor Immunity by Nilberto Dias de Araújo, Fábio Magalhães Gama, Mateus de Souza Barros, Thaís Lohana Pereira Ribeiro, Fabíola Silva Alves, Lilyane Amorim Xabregas, Andréa Monteiro Tarragô, Adriana Malheiro, Allyson Guimarães Costa

“…Recently, cell-mediated immune response in malignant neoplasms has become the focus in immunotherapy against cancer. However, in leukemia, most studies on the cytotoxic potential of T cells have concentrated only on T cells that recognize peptide antigens (Ag) presented by polymorphic molecules of the major histocompatibility complex (MHC). …”
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Inducing apoptosis in acute myeloid leukemia; mechanisms and limitations by Zahra Koolivand, Farbod Bahreini, Elham Rayzan, Nima Rezaei

Subjects: “…Acute myeloid leukemia…”
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Chronic Myelomonocytic Leukemia following Multicentric Castleman Disease by Feng Li, Xiaomei Zhang, Yanting Guo, Yuandong Zhu, Yicun Wu, Yun Ling

“…The coexistence of MCD with chronic myelomonocytic leukemia (CMML) has been rarely reported. Although the pathogenesis remains unclear, this association probably reflects an incidental and fortuitous finding rather than the alteration of a common pluripotent stem cell precursor. …”
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The origins of the definition of complete remission in acute myeloid leukemia by Mark R. Litzow

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Concurrent Central Diabetes Insipidus and Acute Myeloid Leukemia by Stephanie L. Pritzl, Daniel R. Matson, Mark B. Juckett, David J. Ciske

“…Central diabetes insipidus (CDI) is a rare reported complication of acute myeloid leukemia (AML). The onset of AML-associated CDI often precedes the diagnosis of AML by weeks or months and is considered an adverse prognostic indicator in this setting. …”
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Mathematical modeling of cyclic treatments of chronic myeloid leukemia by Natalia L. Komarova

“…Cyclic treatmentstrategies in Chronic Myeloid Leukemia (CML) are characterized byalternating applications of two (or more) different drugs, given oneat a time. …”
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