Phlebotomus perniciosus response to volatile organic compounds of dogs and humans. by Marcos Antonio Bezerra-Santos, Valeria Zeni, Onofrio Marco Pistillo, Stefano Bedini, Ilaria D'Isita, Giovanni Benelli, Giacinto Salvatore Germinara, Petr Volf, Domenico Otranto

“…In this study, we evaluated the olfactory responses of Phlebotomus perniciosus, one of the most important vectors of Leishmania infantum in the Old World. To test the P. perniciosus behavioural response to VOCs, 28 compounds isolated from humans and dogs were assessed using electrophysiological (i.e., electroantennogram, EAG) and behavioural assays (i.e., Y-tube olfactometer). …”
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Antileishmanial Activity of Aldonamides and N-Acyl-Diamine Derivatives by Elaine S. Coimbra, Camila G. Almeida, Wilson V. Júnior, Roberta C. N. Dos Reis, Ana C. F. De Almeida, Luana S. M. Forezi, Mauro V. De Almeida, Mireille Le Hyaric

“…A number of lipophilic N-acyl-diamines and aldonamides have been synthesized and tested for their in vitro antiproliferative activity against Leishmania amazonensis and L. chagasi. Ribonamides, having one amino group, displayed good to moderate inhibition of parasite growth. …”
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Epidemiological analysis of Leishmaniasis prevalence in Pakistan during 2016-2023 by R. Uppal, U. Saeed, M. E. Khattak, A. A. Khan, M. R. Uppal, Z. Z. Piracha, M. N. Khan, D. Shaikh, U. Tariq, A. R. Mahmood, S. S. Ali, B. Muhammad, M. N. Tariq, S. S. Gilani, D. U. Ozsahin, B. Uzun, I. Ozsahin

“…Abstract Leishmaniasis, caused by the Leishmania parasite, remains a persistent public health challenge in Pakistan. …”
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Climate Change and Environmental Influence on Prevalence of Visceral Leishmaniasis in West Pokot County, Kenya by Bulle Abdullahi, Joshua Mutiso, Fredrick Maloba, John Macharia, Mark Riongoita, Michael Gicheru

“…Kala-azar is a parasitic disease caused by Leishmania species transmitted by sand fly. In Kenya, kala-azar is endemic in thirty subcounties spread over in eleven counties in the arid zones. …”
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Historical Spatial Distribution of Zoonotic Diseases in Domestic, Synanthropic, and Wild Animals in the Mexican Territory of the Yucatan Peninsula by Paulina Haro, Enrique Trasviña-Muñoz, Irving May-Concha, Gilberto López-Valencia, Francisco Monge-Navarro, Carloman Herrera-Ramírez, Julio A. Mercado-Rodríguez, Hernán Villanueva-Alonzo, Etienne Waleckx

“…The territory harbors a wide variety of tropical zoonotic pathogens, including Trypanosoma cruzi, Leptospira interrogans, Toxoplasma gondii, Leishmania mexicana, Dirofilaria immitis, and Rickettsia felis. …”
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Structural basis of Spliced Leader RNA recognition by the Trypanosoma brucei cap-binding complex by Harald Bernhard, Hana Petržílková, Barbora Popelářová, Kamil Ziemkiewicz, Karolina Bartosik, Marcin Warmiński, Laura Tengo, Henri Gröger, Luciano G. Dolce, Cameron D. Mackereth, Ronald Micura, Jacek Jemielity, Eva Kowalinski

“…Abstract Kinetoplastids are a clade of eukaryotic protozoans that include human parasitic pathogens like trypanosomes and Leishmania species. In these organisms, protein-coding genes are transcribed as polycistronic pre-mRNAs, which need to be processed by the coupled action of trans-splicing and polyadenylation to yield monogenic mature mRNAs. …”
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Canine Leishmaniosis Control through the Promotion of Preventive Measures Appropriately Adopted by Citizens by Giulia Simonato, Erica Marchiori, Federica Marcer, Silvia Ravagnan, Patrizia Danesi, Fabrizio Montarsi, Carlo Bononi, Gioia Capelli, Mario Pietrobelli, Rudi Cassini

“…Canine leishmaniosis (CanL) is a disease caused by the protist Leishmania infantum and transmitted to dogs by sand fly (Diptera: Phlebotominae) bites. …”
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Protozoan Parasites of Rodents and Their Zoonotic Significance in Boyer-Ahmad District, Southwestern Iran by Zeinab Seifollahi, Bahador Sarkari, Mohammad Hossein Motazedian, Qasem Asgari, Mohammad Javad Ranjbar, Samaneh Abdolahi Khabisi

“…Moreover, 2 to 5 mL of blood was taken from each of the rodents and the sera were examined for anti-Leishmania antibodies, by ELISA, or anti-T. gondii antibodies, by modified agglutination test (MAT). …”
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Cytotoxicity and In Vitro Antileishmanial Activity of Antimony (V), Bismuth (V), and Tin (IV) Complexes of Lapachol by Marcele Neves Rocha, Paula Monalisa Nogueira, Cynthia Demicheli, Ludmila Gonçalvez de Oliveira, Meiriane Mariano da Silva, Frédéric Frézard, Maria Norma Melo, Rodrigo Pedro Soares

“…Leishmania amazonensis is the etiologic agent of the cutaneous and diffuse leishmaniasis often associated with drug resistance. …”
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Diversity and Dynamics of Sand Flies (Diptera: Psychodidae) of Two Cutaneous Leishmaniasis Foci in the Fes-Boulemane Region of Northern Morocco by Fatima Zahra Talbi, Chafika Faraj, Fouad EL-Akhal, Fatiha El Khayyat, Driss Chenfour, Abdellatif Janati Idrissi, Abdelhakim El Ouali Lalami

“…Cutaneous leishmaniasis (CL) is an infectious disease caused by various species of Leishmania and transmitted by several species of sand flies (Diptera: Psychodidae). …”
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Evaluation of Regulatory Immune Response in Skin Lesions of Patients Affected by Nonulcerated or Atypical Cutaneous Leishmaniasis in Honduras, Central America by Gabriela Venicia Araujo Flores, Carmen Maria Sandoval Pacheco, Thaise Yumie Tomokane, Wilfredo Sosa Ochoa, Concepción Zúniga Valeriano, Claudia Maria Castro Gomes, Carlos Eduardo Pereira Corbett, Marcia Dalastra Laurenti

“…In Honduras, Leishmania (L.) infantum chagasi causes both visceral leishmaniasis (LV) and nonulcerated or atypical cutaneous leishmaniasis (NUCL). …”
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The leishmaniases in Kenya: A scoping review. by Grace Grifferty, Hugh Shirley, Katherine O'Brien, Jason L Hirsch, Adrienne M Orriols, Kiira Lani Amechi, Joshua Lo, Neeharika Chanda, Sarra El Hamzaoui, Jorja Kahn, Samantha V Yap, Kyleigh E Watson, Christina Curran, Amina Atef AbdelAlim, Neeloy Bose, Alissa Link Cilfone, Richard Wamai

“…<h4>Background</h4>The leishmaniases are a group of four vector-borne neglected tropical diseases caused by 20 species of protozoan parasites of the genus Leishmania and transmitted through a bite of infected female phlebotomine sandflies. …”
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Nanoemulsified Butenafine for Enhanced Performance against Experimental Cutaneous Leishmaniasis by Adriana Bezerra-Souza, Jéssica A. Jesus, Márcia D. Laurenti, Aikaterini Lalatsa, Dolores R. Serrano, Luiz Felipe D. Passero

“…The production of ergosterol lipid involves the activity of different enzymes and is a crucial event for the Leishmania membrane homeostasis. Such enzymes can be blocked by azoles and allylamines drugs, such as the antifungal butenafine chloride. …”
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An integrative taxonomic approach reveals two putatively novel species of phlebotomine sand fly (Diptera: Psychodidae) in Thailand by Samiullah Soomro, Siwaporn Tuangpermsub, Thongchai Ngamprasertwong, Morakot Kaewthamasorn

“…Abstract Background The subfamily Phlebotominae comprises 1028 species of sand fly, of which only 90 are recognized as vectors of pathogenic agents such as Trypanosoma, Leishmania, and Bartonella. In Thailand, leishmaniasis—a sand fly-borne disease—is currently endemic, with 36 documented sand fly species. …”
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Uncovering the Mechanism of Action of Antiprotozoal Agents: A Survey on Photoaffinity Labeling Strategy by Alessandro Giraudo, Cristiano Bolchi, Marco Pallavicini, Roberto Di Santo, Roberta Costi, Francesco Saccoliti

“…<i>Plasmodium</i>, <i>Leishmania</i>, and <i>Trypanosoma</i> parasites are responsible for infectious diseases threatening millions of people worldwide. …”
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Split-Cre-mediated GFP expression as a permanent marker for flagellar fusion of Trypanosoma brucei in its tsetse fly host by Ruth Etzensperger, Mattias Benninger, Berta Pozzi, Ruth Rehmann, Arunasalam Naguleswaran, Gabriela Schumann, Jan Van Den Abbeele, Isabel Roditi

“…For example, it could be used to determine whether flagellar fusion occurs in related parasites such as Leishmania and Trypanosoma cruzi or to monitor whether intracellular parasites and their hosts exchange proteins.…”
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Identification of a New Pentafluorosulfanyl-Substituted Chalcone with Activity Against Hepatoma and Human Parasites by Alessandra Viperino, Michael Höpfner, Nicole Edel, Ibrahim S. Al Nasr, Waleed S. Koko, Tariq A. Khan, Imen Ben Abdelmalek, Rainer Schobert, Bernhard Biersack, Bianca Nitzsche

“…They were tested for activity against two liver cancer cell lines (HepG2 and HuH-7) and protozoal parasites (<i>Toxoplasma gondii</i> and <i>Leishmania major</i>). Unspecific toxicity and expression of Hsp90 and Hsp70 upon treatment were analyzed in liver cancer cells. …”
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Public Knowledge about and Detection of Canine Visceral Leishmaniasis in Urban Divinópolis, Brazil by Carina Margonari, Júlia Alves Menezes, Marcele Neves Rocha, Kamila Nunes Maia, Michael Éder de Oliveira, Amanda Luisa Fonseca, Fabrizio Furtado de Sousa, Eduardo de Castro Ferreira, Ana Paula Madureira, Maria Norma Melo, Rodrigo Pedro Soares

“…This is the first study demonstrating the occurrence of Leishmania infantum in Divinópolis, suggesting a possible urbanization of VL.…”
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Molecular detection of parasites and host preference in wild-caught Culicoides biting midges (Diptera: Ceratopogonidae) in Chiang Mai and Nakhon Si Thammarat Provinces, Thailand by Kyi Soe Baby, Kaewmee Saowalak, Mano Chonlada, Pattanawong Urassaya, Tipparawong Nopporn, Siriyasatien Padet, Gatherer Derek, Urbaniak Michael D., Bates Paul A., Jariyapan Narissara

“…Here, molecular detection of haemosporidians, Leishmania, trypanosomatids, and filarial nematodes in biting midges was conducted to understand their potential role as vectors, and their host preference was determined. …”
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Antileishmanial Activity of Warifteine: A Bisbenzylisoquinoline Alkaloid Isolated from Cissampelos sympodialis Eichl. (Menispermaceae) by Eliete Cavalcanti da Silva, Cynthia Dias Rayol, Paloma Lys Medeiros, Regina Célia Bressan Queiroz Figueiredo, Márcia Regina Piuvezan, José Maria Brabosa-Filho, Alexsandro Fernandes Marinho, Teresinha Gonçalves Silva, Gardenia Carmen Gadelha Militão, Ana Paula Pimentel Cassilhas, Paulo Paes de Andrade

“…Leishmania (L.) chagasi is the etiological agent of visceral leishmaniasis, an important endemic zoonosis in the American continent, as well as in many other countries in Asia, Africa, and Mediterranean Europe. …”
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