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Involvement of Different CD4+ T Cell Subsets Producing Granzyme B in the Immune Response to Leishmania major Antigens
Published 2014-01-01“…The nature of effector cells and the potential immunogenicity of Leishmania major excreted/secreted proteins (LmES) were evaluated using peripheral blood mononuclear cells (PBMCs) from healed zoonotic cutaneous leishmaniasis individuals (HZCL) and healthy controls (HC). …”
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Contribution of epidermal growth factor (EGF) in the treatment of cutaneous leishmaniasis caused by Leishmania major in BALB/c mice.
Published 2025-01-01“…Seventy-two mice were infected with Leishmania major parasites and randomly divided into eight treatment groups after the appearance of the lesion. …”
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A short ncRNA modulates gene expression and affects stress response and parasite differentiation in Leishmania braziliensis
Published 2025-02-01Subjects: Get full text
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Quantification of Soluble or Insoluble Fractions of Leishmania Parasite Proteins in Microvolume Applications: A Simplification to Standard Lowry Assay
Published 2020-01-01“…A method for fast and accurate qualitative and/or quantitative determination of total soluble/insoluble proteins or micro-well plate immobilized proteins isolated from Leishmania parasites in microvolumes was described in the current study. …”
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A review of leishmaniasis: current knowledge and future directions of heterocyclic molecules
Published 2024-09-01Subjects: “…leishmania…”
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4-Aminoquinoline as a privileged scaffold for the design of leishmanicidal agents: structure–property relationships and key biological targets
Published 2025-01-01Subjects: Get full text
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<i>Borrelia</i>, <i>Leishmania</i>, and <i>Babesia</i>: An Emerging Triad of Vector-Borne Co-Infections?
Published 2025-01-01“…Canine leishmaniosis (CanL), caused by the protozoan <i>Leishmania infantum</i> and transmitted primarily by phlebotomine sand flies, poses significant challenges for zoonotic disease management [...]…”
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Novel Arsenic Nanoparticles Are More Effective and Less Toxic than As (III) to Inhibit Extracellular and Intracellular Proliferation of Leishmania donovani
Published 2014-01-01“…Visceral leishmaniasis, a vector-borne tropical disease that is threatening about 350 million people worldwide, is caused by the protozoan parasite Leishmania donovani. Metalloids like arsenic and antimony have been used to treat diseases like leishmaniasis caused by the kinetoplastid parasites. …”
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A Novel Multiplex LAMP Assay for the Rapid and Accurate Diagnosis of Visceral Leishmaniasis Caused by Leishmania infantum from Iran
Published 2023-01-01“…We aimed to develop and validate a multiplex LAMP assay for the diagnosis of VL caused by Leishmania infantum (L. infantum). Moreover, a thorough assessment was conducted to determine the effectiveness of multiplex LAMP in identifying various Leishmania species, such as Leishmania tropica (L. tropica) and Leishmania major (L. major) in comparison to Leishmania infantum (L. infantum). …”
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Differential Immune Response against Recombinant Leishmania donovani Peroxidoxin 1 and Peroxidoxin 2 Proteins in BALB/c Mice
Published 2015-01-01“…We assessed the immune response against recombinant proteins of two related, albeit functionally different, peroxidoxins from Leishmania donovani: peroxidoxin 1 (LdPxn1) and peroxidoxin 2 (LdPxn2) in BALB/c mice. …”
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First Comprehensive List of Phlebotomine Sand Fly Species (Diptera: Psychodidae) in a Leishmaniasis Focus (Djelfa, Algeria), Including the First Record of Phlebotomus langeroni Fem...
Published 2024-09-01Subjects: “…Sand fly; Environmental factors; Leishmania; Djelfa; Algeria…”
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Synthesis and evaluation of nitrochromene derivatives as potential antileishmanial therapeutics through biological and computational studies
Published 2025-01-01Subjects: Get full text
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Construction of Two mCherry Plasmids (pXG-mCherry) for Transgenic Leishmania: Valuable Tools for Future Molecular Analysis
Published 2017-01-01“…Leishmania is the causative agent of leishmaniasis, a neglected tropical disease that affects more than 12 million people around the world. …”
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Lack of Hypoxia Inducible Factor-1α Influences on Macrophages Ability to Deal with Leishmania braziliensis In Vitro and Affects Pathology In Vivo
Published 2025-05-01Subjects: Get full text
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Infectiousness to sand flies of a cat naturally infected with Leishmania infantum at the moment of diagnosis and after three different courses of treatment
Published 2025-02-01“…Abstract In this study, an evaluation was made of three treatments against feline leishmaniosis (FeL) and their impacts on the transmission of Leishmania infantum to its vector, Lutzomyia longipalpis. …”
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Oxidative stress-driven enhanced iron production and scavenging through Ferroportin reorientation worsens anemia in antimony-resistant Leishmania donovani infection.
Published 2025-01-01“…Despite the withdrawal of pentavalent-antimonials in treating Visceral leishmaniasis from India, recent clinical isolates of Leishmania donovani (LD) exhibit unresponsiveness towards pentavalent-antimony (LD-R). …”
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Lipid Isolated from a Leishmania donovani Strain Reduces Escherichia coli Induced Sepsis in Mice through Inhibition of Inflammatory Responses
Published 2014-01-01“…We have reported earlier that the lipid of attenuated Leishmania donovani suppresses the inflammatory responses in arthritis patients. …”
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