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A novel strain of Leishmania braziliensis harbors not a toti- but a bunyavirus.
Published 2024-12-01“…Leishmania is a genus of the family Trypanosomatidae that unites obligatory parasitic flagellates causing a variety of vector-borne diseases collectively called leishmaniasis. …”
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Sex-Related Differences in Immune Response and Symptomatic Manifestations to Infection with Leishmania Species
Published 2019-01-01“…Worldwide, an estimated 12 million people are infected with Leishmania spp. and an additional 350 million are at risk of infection. …”
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Calophyllum brasiliense Modulates the Immune Response and Promotes Leishmania amazonensis Intracellular Death
Published 2018-01-01“…This study showed the leishmanicidal and immunomodulatory effects of a 30 μg/mL of hydroalcoholic extract of C. brasiliense in murine macrophages before and after Leishmania (Leishmania) amazonensis infection. The semiquantitative cytokine RNA expression was determined by RT-PCR and the anti-Leishmania activity was measured by infection index (IF). …”
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Detection of leishmania infantum seropositivity in dogs by elisa technique in thrace region of turkey
Subjects: “…leishmania infantum…”
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Comparison of ELISA and IFAT for Leishmania infantum by European and Middle Eastern diagnostic laboratories
Published 2024-12-01Subjects: Get full text
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Analysis of the IGS rRNA Region and Applicability for Leishmania (V.) braziliensis Characterization
Published 2020-01-01“…The specific primer system for L. braziliensis showed S=10 fg, ε=98.08%, and logσ=103 for Leishmania naiffi; logσ=104 for Leishmania guyanensis; and logσ=105 for Leishmania shawi. …”
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Risk Factors Associated with Leishmaniasis in the Most Affected Provinces by Leishmania infantum in Morocco
Published 2020-01-01“…The risk study of the affected foci is of great value for the control and surveillance of this endemic disease, especially in the provinces where Leishmania infantum predominates. Methods. This study concerned nine provinces located in the extreme and central north of Morocco (Taounate, Taza, Chefchaouen, Al Hoceima, Larache, Tétouane, Tanger-Assilah, M’diq-Fnideq, and Fahs-Anjra Provinces). …”
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Mucosal leishmaniasis is associated with the Leishmania RNA virus and inappropriate cutaneous leishmaniasis treatment.
Published 2025-01-01“…<h4>Background</h4>Mucosal leishmaniasis (ML) is a severe clinical form of leishmaniasis that is characterized by the destruction of the nasal and/or the oral mucosae and appears as a late complication in 5% to 10% of cutaneous leishmaniasis (CL) cases produced by species belonging to Leishmania (Viannia) subgenus. Some strains of Leishmania spp. carry an RNA virus known as Leishmania RNA virus (LRV) that may contribute to the appearance of ML.…”
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Pharmacological inhibition of key metabolic pathways attenuates Leishmania spp infection in macrophages.
Published 2025-01-01“…We also analyzed the effects of both Leishmania spp. strain infection on mitochondria function, further revealing that infected cells display heightened mitochondrial mass and membrane potential. …”
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Peroxisome Proliferator-Activated Receptor-γ-Mediated Polarization of Macrophages in Leishmania Infection
Published 2012-01-01“…Leishmanial activation of PPARγ promotes survival, whereas blockade of PPARγ facilitates removal of the parasite. Thus, Leishmania parasites harness PPARγ to increase infectivity.…”
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Effect of Environmental Disturbance on the Population of Sandflies and Leishmania Transmission in an Endemic Area of Venezuela
Published 2014-01-01“…The results show the anthropogenic disturbance effect on the sandflies population and Leishmania transmission in endemic areas of Venezuela. …”
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Dendritic Cells and Leishmania Infection: Adding Layers of Complexity to a Complex Disease
Published 2016-01-01“…In this review, we discuss (1) the interactions between DCs and parasites from different species of Leishmania and (2) the crosstalk of DCs and other cells during CL infection. …”
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Screening of six medicinal plant species for antileishmanial activity
Published 2021-09-01Subjects: Get full text
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Management of Canine Leishmaniasis and the Treatment Trends of Veterinarians in Aegean Region of Türkiye: A Questionnaire-based Survey
Published 2024-12-01Subjects: Get full text
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Ultrastructural Analysis of Leishmania infantum chagasi Promastigotes Forms Treated In Vitro with Usnic Acid
Published 2015-01-01“…The aim of this study was to evaluate the antileishmanial activity of usnic acid on Leishmania infantum chagasi promastigotes and the occurrence of drug-induced ultrastructural damage in the parasite. …”
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Subversion of Immunity by Leishmania amazonensis Parasites: Possible Role of Phosphatidylserine as a Main Regulator
Published 2012-01-01“…Leishmania amazonensis parasites cause progressive disease in most inbred mouse strains and are associated with the development of diffuse cutaneous leishmaniasis in humans. …”
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Within-host bayesian joint modeling of longitudinal and time-to-event data of Leishmania infection.
Published 2024-01-01“…In this work, we present a Bayesian joint model of longitudinal and time-to-event data of Leishmania infection that considers the interplay between key drivers of the disease process: pathogen load, antibody level, and disease. …”
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Natural Product Identification and Molecular Docking Studies of Leishmania Major Pteridine Reductase Inhibitors
Published 2024-12-01Subjects: Get full text
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Mixed Cutaneous Infection Caused by Leishmania and Dermatophytes: A Rare Coincidence or Immunological Fact
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Corrigendum to “Dendritic Cells and Leishmania Infection: Adding Layers of Complexity to a Complex Disease”
Published 2018-01-01Get full text
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