Barriers and facilitators to high-volume evidence-based innovation and implementation in a large, community-based learning health system by Cimone Durojaiye, Stephanie Prausnitz, Jennifer L. Schneider, Tracy A. Lieu, Julie A. Schmittdiel, Smita Rouillard, Yi-Fen Chen, Kristine Lee, Douglas A. Corley

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Moving from a registry to a learning health system: A case study of a Dutch prostate cancer registry by Tom Belleman, Jeroen D. H. vanWijngaarden, Malou C. P. Kuppen, Saskia deGroot, Kim J. M. van derVelden, Dianne Bosch, Inge M. vanOort, Carin A. Uyl‐de Groot, Welmoed K. vanDeen

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Four distinct models of learning health systems: Strength through diversity by Charles P. Friedman, Sarah M. Greene

Subjects: “…learning health systems…”
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How senior leaders support innovations in large learning health systems: Insights from United States Veterans Health Administration national program office leaders by Jaifred Christian F. Lopez, Sallie Allgood, Kate Sheahan, Brandolyn White, M. Amy Kirshner, Suzanne Shirley, Madison Coffey, Amanda Milo, Sarah L. Cutrona, Laura Damschroder, Gemmae M. Fix, Andrea L. Nevedal, Caitlin M. Reardon, Marilla A. Opra Widerquist, Maria Arasim, Allen L. Gifford, Kathryn DeLaughter, George L. Jackson

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Virtual simulator in oncology for teaching catheter care fully implemented for nursing students: experimental study by Maria das Graças Silva Matsubara Matsubara, Eliza Costa Cijevschi, Leticia Faria Serpa, Antônio Valerio Netto, Daiane Arruda Saraiva, Rita Tarcia

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Analyzing electronic medical records to extract prepregnancy morbidities and pregnancy complications: Toward a learning health system by Yitayeh Belsti, Lisa Moran, Aya Mousa, Rebecca Goldstein, Daniel Lorber Rolnik, Mahnaz Bahri Khomami, Mihiretu M. Kebede, Helena Teede, Joanne Enticott

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The surprising politics of learning health systems by Adalsteinn Brown, Robert J. Reid

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A Call-To-Action: Integrate A Learning Health System Framework into Longitudinal Population Studies to Improve Health Response in Africa. by Kadengye, Damazo T., Kiragga, Agnes N.

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Transforming Health Care Through Research: Highlights From the 2025 Annual Conference of the Health Care Systems Research Network by Michael A. Horberg, Suzanne Simons

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The BrainHealth Databank: a systems approach to data-driven mental health care and research by Jose Arturo Santisteban, David Rotenberg, Stefan Kloiber, Stefan Kloiber, Marta M. Maslej, Marta M. Maslej, Adeel Ansari, Bahar Amani, Darren Courtney, Darren Courtney, Farhat Farrokhi, Natalie Freeman, Masooma Hassan, Lucia Kwan, Mindaugas Mozuraitis, Michael Lau, Natalia Potapova, Farhad Qureshi, Nicole Schoer, Nelson Shen, Nelson Shen, Joanna Yu, Noelle Coombe, Kimberly Hunter, Kimberly Hunter, Kimberly Hunter, Peter Selby, Peter Selby, Nicole Thomson, Nicole Thomson, Damian Jankowicz, Damian Jankowicz, Sean L. Hill, Sean L. Hill

Subjects: “…learning health system…”
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Nursing students’ academic burnout: its prevalence and association with self-efficacy, psychological distress, and quality of learning experience by Shaherah Yousef Andargeery, Elaf Abdulrahman Altaweel, Fatima Salem Alkorbi, Lamia Abdulaziz Alyousef, Bushra Fayez Alanazi, Sara Haroon Idriss, Sara Salem Alqahtani, Lana Mohammed Alkhamis

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Moving from crisis response to a learning health system: Experiences from an Australian regional primary care network by Bianca Forrester, Georgia Fisher, Louise A. Ellis, Andrew Giddy, Carolynn L. Smith, Yvonne Zurynski, Lena Sanci, Katherine Graham, Naomi White, Jeffrey Braithwaite

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Seeing the random forest through the decision trees. Supporting learning health systems from histopathology with machine learning models: Challenges and opportunities by Ricardo Gonzalez, Ashirbani Saha, Clinton J.V. Campbell, Peyman Nejat, Cynthia Lokker, Andrew P. Norgan

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A learning health system model for addressing substance use: Denver Health Center for Addiction Medicine by Emily Bacon, Laura J. Podewils, Brooke Bender, Joshua Blum, Christian Thurstone, Alia Al‐Tayyib, John Mills, Alexandra R. Tillman, Judith Shlay

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Editorial: Building a learning health system in pediatric rheumatology by Esi M. Morgan, Constance A. Mara, Sheetal S. Vora, Beth S. Gottlieb

Subjects: “…learning health system…”
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How an evidence synthesis program's growth has supported research use and learning community partnership networks within a learning health system: A descriptive analysis and case s... by Isomi Miake‐Lye, Selene Mak, Tom Valente, Nicole Floyd, Paul Shekelle

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Identifying factors influencing emerging innovations in hospital discharge decision making in response to system stress: a qualitative study by Allison M. Gustavson, Matthew J. Miller, Natassia Boening, Emily M. Hudson, Jennifer P. Wisdom, Robert E. Burke, Hildi J. Hagedorn

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Towards a learning healthcare community in the Bronx: evaluating the Bridging Research, Accurate Information and Dialogue (BRAID) model by Sarah M. McNeilly, Katherine W. Wang, Sarah A. Jacobs, Nang S. Yone, Debra A. Williams, Bruce D. Rapkin, Caroline Davis Joseph, Damara N. Gutnick

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Development of transient ischemic attack risk prediction model suitable for initializing a learning health system unit using electronic medical records by Jian Wen, Tianmei Zhang, Shangrong Ye, Cheng Li, Ruobing Han, Ran Huang, Bairong Shen, Anjun Chen, Qinghua Li

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Implementing Learning from Excellence in a postanaesthesia care unit: a qualitative study of healthcare professionals’ experiences after six months by Gørill Birkeli, Ellen Catharina Tveter Deilkås, Randi Ballangrud, Anne Karin Lindahl

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