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  1. 7501
  2. 7502

    Acceptability of the R21/Matrix-M malaria vaccine alongside existing malaria interventions in the trial context by Jayne Webster, Brian Greenwood, Daniel Chandramohan, Alassane Dicko, Issaka Sagara, Djibrilla Issiaka, Adrian VS Hill, Halimatou Diawara, Fatoumata Koita, Seydou Traoré, Jane Grant, Mehreen Datoo, Mala Sylla, Abdrahmane Boncane Dicko

    Published 2025-02-01
    “…These perceptions of the acceptability of the R21/Matrix-M vaccine led to a reduced perceived importance of seasonal malaria chemoprevention (SMC) among some caregivers, while others viewed R21/Matrix-M, SMC and insecticide-treated nets as complementary.Conclusions The R21/Matrix-M vaccine was acceptable to caregivers and communities of participants in the R21/Matrix-M phase III trial in Mali. …”
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  3. 7503
  4. 7504

    Brassinosteroid Enhances Cucumber Stress Tolerance to NaHCO<sub>3</sub> by Modulating Nitrogen Metabolism, Ionic Balance and Phytohormonal Response by Wenjing Nie, Biao Gong, Dan Wen, Peng Qiao, Hongen Guo, Qinghua Shi

    Published 2024-12-01
    “…NaHCO<sub>3</sub> stress disrupted nitrogen metabolism, as evidenced by reductions in the activities of NR, GS, GOGAT, GOT, and GPT, along with altered GDH activity. These disruptions led to an accumulation of NH<sub>4</sub><sup>+</sup> and substantial decreases in NO<sub>3</sub><sup>−</sup>-N and total nitrogen content. …”
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  5. 7505
  6. 7506

    Hepatoprotection and Phytochemistry of the Vietnamese Herbs Cleome chelidonii and Cleome viscosa Stems by Nhat Minh Phan, Thi Hong Tuoi Do, Le Thanh Tuyen Nguyen, Trong Tuan Nguyen, Quoc Luan Ngo, Trong Duc Tran, Quan Hien Nguyen, Bui Linh Chi Huynh, Diep Xuan Ky Nguyen, Trong Dat Bui, Dinh Tri Mai, Tan Phat Nguyen

    Published 2021-01-01
    “…Further, phytochemical studies of these ones were conducted and led to the identification of eight flavonoids: visconoside A (1), visconoside B (2), quercetin 3-O-β-D-glucopyranoside 7-O-α-L-rhamnopyranoside (3), kaempferol 3-O-β-D-glucopyranoside 7-O-α-L-rhamnopyranoside (4), cleomeside A (5), cleomeside B (6), cleomeside C (7), and quercetin-3-O-[β-D-glucopyranosyl-(1⟶2)]-α-L-rhamnopyranoside 7-O-α-L-rhamnopyranoside (8). …”
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  7. 7507

    Exploring the functional role of POU5F1 using CRISPR RNP electroporation of zygote (CRISPR-EZ) in buffaloes by Meeti Punetha, Dharmendra Kumar, Suman Choudhary, Sheetal Saini, Kamlesh Kumari Bajwa, Surabhi Sharma, Manu Mangal, P. S. Yadav, T. K. Datta

    Published 2023-11-01
    “…We targeted the buffalo POU5F1 gene using the abovementioned parameters, which caused nonsense-mediated mRNA decay and led to complete knockout (KO) of the POU5F1 gene. …”
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  8. 7508

    HnRNPM modulates alternative splicing in germ cells by recruiting PTBP1 by Peng Lv, Wenchao Xu, Sheng Xin, Yuanxuan Deng, Bin Yang, Dengjianyi Xu, Jian Bai, Deilin Ma, Tao Wang, Jihong Liu, Xiaming Liu

    Published 2025-01-01
    “…Therefore, we generated a germ cell-specific hnRNPM conditional knockout mouse model to investigate the role of hnRNPM in spermatogenesis. A lack of hnRNPM led to male infertility under natural conditions. …”
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  9. 7509

    Interrelationship between altered metabolites and the gut microbiota in people living with HIV with different immune responses to antiretroviral therapy by Xuebin Tian, Zhongyao Gao, Yiwen Xie, Xiangyun Lu, Yulong Zhao, Peng Yao, Mingqing Dong, Lifeng Yu, Nanping Wu

    Published 2025-01-01
    “…Moreover, mRNA expression analysis showed that Indole-3-acetyl-beta-1-D-glucoside treatment led to a suppression of pro-inflammatory cytokines. …”
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  10. 7510

    Endovascular therapy versus best medical care for acute ischemic stroke with distal medium vessel occlusion: a systematic review and meta-analysis by Ziyue Wang, Jiacheng Li, Qianqian Kong, Hao Yan, Yi Zhang, Xirui Zhou, Zhiyuan Yu, Hao Huang, Xiang Luo

    Published 2025-12-01
    “…There were no significant differences in excellent functional outcome (OR: 1.21, 95% CI: 0.99-1.47), good functional outcome (OR: 1.03, 95% CI: 0.82-1.30) and 90-day mortality (OR: 1.17, 95% CI: 0.84-1.62). Additionally, EVT led to higher sICH (OR: 1.64, 95% CI: 1.09-2.47) and better ENI (OR: 1.50, 95% CI: 1.02-2.19) compared to BMT. …”
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  11. 7511

    Cardiac Gene Therapy With Phosphodiesterase 2A Limits Remodeling and Arrhythmias in Mouse Models of Heart Failure by Rima Kamel, Aurélia Bourcier, Jean Piero Margaria, Valentin Jin, Audrey Varin, Agnès Hivonnait, Françoise Mercier‐Nomé, Delphine Mika, Alessandra Ghigo, Flavien Charpentier, Vincent Algalarrondo, Emilio Hirsch, Rodolphe Fischmeister, Grégoire Vandecasteele, Jérôme Leroy

    Published 2025-02-01
    “…Methods and Results C57BL/6 male mice were injected with serotype 9 adeno‐associated viruses encoding for PDE2A. This led to a ≈10‐fold rise of PDE2A protein levels that affected neither cardiac structure nor function in healthy mice. …”
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  12. 7512

    Physiological changes induced by green fodder expansion into grasslands and croplands enhance water-use efficiency in the Northeastern Tibetan Plateau by Xu Wang, Jilin Yang, Jie Wang, Tong Yang, Chuchen Chang, Yanbo Zhao, Xiaocui Wu, Geli Zhang, Xiangming Xiao

    Published 2025-02-01
    “…However, we found that green fodder planting also led to increased soil evaporation over the non-growing season, which partially offset its positive effect on water-use efficiency during the growing season. …”
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  13. 7513

    Composite microbial agent improves cotton yield and resource use efficiency under mild salt stress by optimizing plant resource allocation by Xiao Zhao, Panpan Guo, Xiong Wu, Meng Zhu, Shaozhong Kang, Taisheng Du, Jian Kang, Jinliang Chen, Ling Tong, Risheng Ding, Wanli Xu, Guangmu Tang

    Published 2025-04-01
    “…Under G1S2, STC-PGPR reduced the root-shoot ratio, directing more resources to shoots, which led to increases in SY, irrigation water productivity, and NPFP by 46.2 %, 44.8 %, and 45.9 %, respectively. …”
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  14. 7514

    A network comparison on efficacy and safety profiling of PD-1/PD-L1 inhibitors in first-line treatment of advanced non-small cell lung cancer by Jie Fu, Jie Fu, Yi-Dan Yan, Xu Wan, Xiao-Fan Sun, Xiao-Fan Sun, Xiu-Mei Ma, Ying-Jie Su

    Published 2025-01-01
    “…In analyses of all patients, penpulimab plus chemotherapy led the way for OS (HR 0.55, 95% CI: 0.40–0.75) and PFS (HR 0.43, 95% CI: 0.27–0.67). …”
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  15. 7515

    Achieving equiaxed and lamellar TiAl alloys via cold-cathode electron beam additive manufacturing with dual-wire synergistic control by Yilei Shi, Shuili Gong, Haiying Xu, Wei Chen, Zhuang Wang, Guang Yang, Xin Liu, Bojin Qi

    Published 2025-01-01
    “…Compared to the lamellar microstructure of Ti48Al alloy, the Ti48Al1Mo0.45Zr0.3Si alloy exhibits a dual-γ phase microstructure, consisting of fine lamellar colonies and equiaxed γ grains. This modification led to a 90% and 150% increase in elongation at room temperature and 650 °C, respectively. …”
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  16. 7516

    Genome-wide transcriptome analysis and drug target discovery reveal key genes and pathways in thyroid cancer metastasis by Minjing Zou, Amal Qattan, Monther Al-Alwan, Hazem Ghebeh, Naif Binjumah, Latifa Al-Haj, Khalid S. A. Khabar, Abdulmohsen Altaweel, Falah Almohanna, Abdullah M. Assiri, Abdelilah Aboussekhra, Ali S. Alzahrani, Ali S. Alzahrani, Yufei Shi

    Published 2025-02-01
    “…Mertk, a member of the TAM (Tyro, Axl, Mertk) family of RTKs, was also overexpressed in Met cells, which led to increased MAPK activation, epithelial–mesenchymal transition (EMT), and enrichment of cancer stem cells. …”
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  17. 7517
  18. 7518

    Risks of psychological traumatization and stress adaption of medical staff working under war conditions (analytical literature review) by M.V. Krasnoselskyi, O.O. Kyrylova, O.Ye. Dubenko, T.V. Rublova, Yu.V. Pavlichenko

    Published 2023-12-01
    “…The importance of medical and psychological aid aimed at decreasing stress and stabilizing psychoemotional state of the medical staff who are working under the conditions of war led to development of a large number of programs in various psychotherapeutic areas that have shown their high effectiveness.…”
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  19. 7519

    Early sST2 Liberation after Implantation of a Left Ventricular Assist Device in Patients with Advanced Heart Failure by Philipp Opfermann, Elisabeth Simader, Alessia Felli, Michele Bevilacqua, Caroline Holaubek, Martin Dworschak, Mohamed Mouhieddine, Daniel Zimpfer, Jan Hendrik Ankersmit, Barbara Steinlechner

    Published 2020-01-01
    “…., cardiac output) and frequency of infections during the hospital stay. Results. LVAD therapy led to an immediate and significant improvement of the hemodynamic parameters in 1-year survivors and nonsurvivors alike. …”
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  20. 7520

    Features of the functioning of the hypothalamic-pituitary-thyroid axis in mice with Lewis carcinoma on the background of induced hyperthyroidism by E. M. Frantsiyants, V. A. Bandovkina, I. V. Kaplieva, I. V. Neskubina, E. I. Surikova, A. I. Shikhlyarova, L. K. Trepitaki, M. A. Gusareva, I. A. Udalenkova, E. O. Vasilieva, N. D. Cheryarina, V. V. Pozdnyakova

    Published 2024-09-01
    “…High levels of T3 in blood serum and skin stimulated the proliferation of tumor cells, which led to the formation of subcutaneous tumors of a larger volume in the mice of the main group. …”
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