October 7th Mass Casualty Attack in Israel: Injury Profiles of Hospitalized Casualties by Sharon Goldman, MPH, Ari M. Lipsky, MD, Irina Radimislensky, BSc, Adi Givon, BSc, Ofer Almog, MD, Avi Benov, MD, Israel Trauma Group, Eldad Katorza, MD, MSC, MBA, H. Bahouth, A. Bar, A. Braslavsky, D. Czeiger, D. Fadeev, A. L. Goldstein, I. Grevtsev, G. Hirschhorn, I. Jeroukhimov, A. Kedar, Y. Klein, A. Korin, B. Levit, I. Schrier, A. D. Schwarz, W. Shomar, D. Soffer, M. Weiss, O. Yaslowitz, I. Zoarets

“…On Saturday, October 7th, approximately 3000 Hamas-led terrorists infiltrated Israel’s southern border and attacked civilians and soldiers. …”
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Randomized controlled trial of cognitive behavioral therapy versus health education for sleep disturbance and fatigue following stroke and traumatic brain injury by Lucy Ymer, Adam McKay, Dana Wong, Kate Frencham, Natalie Grima, Monique Roper, Sylvia Nguyen, Jade Murray, Gershon Spitz, Jennie Ponsford

“…Conclusions: Both cognitive behavioural therapy for sleep and fatigue and health education led to improvement in sleep and fatigue; however, effects were larger and more rapid for cognitive behavioural therapy for sleep and fatigue immediately post-treatment. …”
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Release velocity ImprovemenT with a new Metronome guIding chest COmpressions: The RITMICO simulation study by Maria Luce Caputo, Giuliana Monachino, Ruggero Cresta, Alessia Currao, Enrico Baldi, Simone Savastano, Andrea Cortegiani, Mariachiara Ippolito, Sara Accetta, Alessandra Gargano, Camilla Metelmann, Bibiana Metelmann, Carlos Ramon Hölzing, Julian Ganter, Michael Patrick Müller, Claudio Benvenuti, Stefania Tomola, Pierangelo Pinetti, Pier Luigi Ingrassia, Francesca Dalia Faraci, Angelo Auricchio

“…The double-click metronome led to significant improvements in CC depth and CCRV across all volunteer categories, with the greater effect observed in first responders and in non-specialized healthcare personnel. …”
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Differences in Arrhythmia Detection Between Harvard Step Test and Maximal Exercise Testing in a Paediatric Sports Population by Massimiliano Bianco, Fabrizio Sollazzo, Riccardo Pella, Saverio Vicentini, Samuele Ciaffoni, Gloria Modica, Riccardo Monti, Michela Cammarano, Paolo Zeppilli, Vincenzo Palmieri

“…RESULTS: HST resulted in a lower peak heart rate than MET (181.1 ± 9.8 vs. 187.5 ± 8.1 bpm, <i>p</i> < 0.001), but led to the detection of more supraventricular (18.6% vs. 13.1%, <i>p</i> < 0.001) and ventricular (30.5% vs. 22.7%, <i>p</i> < 0.001) arrhythmias, clustering during recovery (<i>p</i> = 0.014). …”
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Drought-induced shifts in gross primary production pathways in Moso bamboo forests: Insights from improved BIOME-BGC and structural equation modeling by Zhaodong Zheng, Fangjie Mao, Huaqiang Du, Xuejian Li, Fengfeng Ye, Xianfeng Teng, Ningxin Yang, Jiacong Yu, Meixuan Song, Yinyin Zhao

“…Drought during different growing seasons (Rapid Growing Season, Main Growing Season, and Final Growing Season) led to decreases in daily GPP of 0.44, 0.52, and 0.28 g C m−2 day−1, respectively. (3) The combined analysis using RF and SEM reveals that temperature and stomatal conductance are the most critical environmental and physiological factors driving GPP variations. …”
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Blue rings in trees and shrubs as indicators of early and late summer cooling events at the northern treeline by Agata Buchwal, Agata Buchwal, Pawel Matulewski, Ylva Sjöberg, Alma Piermattei, Alma Piermattei, Alan Crivellaro, Alan Crivellaro, Angela Balzano, Maks Merela, Luka Krže, Katarina Čufar, Alexander V. Kirdyanov, Alexander V. Kirdyanov, Tatiana Bebchuk, Tito Arosio, Ulf Büntgen, Ulf Büntgen, Ulf Büntgen

“…The high temperature sensitivity of pine trees in northern Fennoscandia has led to some of the most reliable tree-ring climate reconstructions in the world for the past millennia. …”
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Construction of an anaplastic thyroid cancer stratification signature to guide immune therapy selection and validation of the pivotal gene HLF through in vitro experiments by Li Pengping, Yin Kexin, Xie Yuwei, Sun Ke, Li Rongguo, Wang Zhenyu, Jin Haigang, Wang Shaowen, Huang Yuqing

“…Through weighted gene co-expression network analysis (WGCNA), we identified 12 differentially expressed genes closely associated with immunotherapy outcomes. This led to the creation of a refined signature for predicting ATC’s immune responsiveness to anti-PD1 therapy, which was further validated using thyroid cancer cohorts from TCGA and nine melanoma cohorts from clinical trials. …”
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Tracking Persistent Symptoms in Scotland (TraPSS): a longitudinal prospective cohort study of COVID-19 recovery after mild acute infection by Jane Ormerod, Nicholas F Sculthorpe, Marie McLaughlin, Luke Cerexhe, Eilidh Macdonald, Antonio Dello Iacono, Nilihan E M Sanal-Hayes, Joanne Ingram, Rachel Meach, David Carless, Lawrence D Hayes

“…Background COVID-19 disease results in disparate responses between individuals and has led to the emergence of long coronavirus disease (Long-COVID), characterised by persistent and cyclical symptomology. …”
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Mitophagy mediated by HIF-1α/FUNDC1 signaling in tubular cells protects against renal ischemia/reperfusion injury by Wenjun Zhang, Chao Guo, Yi Li, Hao Wang, Huabing Wang, Yingying Wang, Tingting Wu, Huinan Wang, Gang Cheng, Jiangwei Man, Siyu Chen, Shengjun Fu, Li Yang

“…Pretreatment of the rat RIRI model with roxadustat, a novel oral HIF-1α inhibitor, led to decreased renal injury and apoptosis in vivo. …”
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Participant experiences in HIV cure-directed trial with an extended analytical treatment interruption in Philadelphia, United States by Andrea Bilger, Eion Plenn, Frances K. Barg, Katharine A. Rendle, William B. Carter, Andrea Lamour-Harrington, Nora Jones, Beth Peterson, John A. Sauceda, Pablo Tebas, Karam Mounzer, David Metzger, Luis J. Montaner, Karine Dubé

“…Other participants were nervous during the ATI. Rising viral loads led some to feel a sense of failure. Although trial experiences were heterogeneous, participants unanimously had positive interactions with the clinical trial staff which facilitated their retention in the trial. …”
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Insights on the effect of mega-carcass abundance on the population dynamics of a facultative scavenger predator and its prey by Sidous, Mellina, Cubaynes, Sarah, Gimenez, Olivier, Drouet-Hoguet, Nolwenn, Dray, Stéphane, Bollache, Loïc, Madhlamoto, Daphine, Ngwenya, Nobesuthu Adelaide, Fritz, Hervé, Valeix, Marion

“…We used the semi-natural experimental opportunity in Hwange National Park, Zimbabwe, where contrasted management measures (culling and artificial supply of water) have led to fluctuations in elephant carrion abundance, to identify the consequences of facultative scavenging on the population dynamics of a large mammalian carnivore, the spotted hyaena (Crocuta crocuta), and its prey. …”
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Have crops already reached peak suitability: assessing global climatic suitability decreases for crop cultivation by Vhiny-Guilley Mombo, Mathilde Duvallet, Michiel Schaeffer, Florent Baarsch

“…The increased risk of food supply shortages led by climatic suitability loss may trigger increased deforestation if adaptation measures are not implemented.…”
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Integrated bioinformatics analysis of the effects of chronic pain on patients with spinal cord injury by Jinlong Zhang, Jinlong Zhang, Longju Qi, Yuyu Sun, Yuyu Sun, Shiyuan Chen, Jinyi Liu, Jiaxi Chen, Fangsu Yan, Wenqi Wang, Qinghua Wang, Liang Chen

“…Lastly, we analyzed the hub genes to explore the transcription factor network, potential therapeutic drugs, and ceRNA networks.ConclusionThe analysis of 15 hub genes as significant biological markers for SCI and chronic pain has led to the identification of several potential drugs for treatment.…”
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Evaluation of the planting performance for planting substrate using the SQI-CRITIC combination model based on the least squares method by Ning Wang, Dong Xia, Dong Xia, Dong Xia, Xiaoming Duan, Bingqin Zhao, Bingqin Zhao, Wennian Xu, Wennian Xu

“…BackgroundTo improve the scientificity of the evaluation results of the planting performance of the Yellow River sediment based on planting substrate.MethodsThis study replaced the natural soil with Yellow River sediment, used cement as the cementing material, added different proportions of organic matter and amendment of habitat material to prepare planting substrate based on the Yellow River sediment, and carried out experiments by using oats and proposed a combined SQI-CRITIC combined weighting calculation method based on the least square method for its evaluation.ResultsThe results showed that (1) different proportions of cement and amendment of habitat material led to significant variations in the planting performance of the planting substrate based on Yellow River sediment: among the 5# mix ratio, the plant height (12.5 cm) and biomass (3.06 g) of oats reached extreme values. …”
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Long-term Prospective Comparative Analysis of Ototoxic and Survival Outcomes of Sequential Boost and Simultaneous Integrated Boost of Volumetric Modulated Arc Therapy for Head-Neck... by Nidhin Das, Sri Harsha Kombathula, Vidhu Sharma, Puneet Pareek, Kapil Soni, Amit Goyal

“…We also investigated other significant late toxicities that led to dysphagia, voice changes, and xerostomia. …”
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Assessment of risk communication and community engagement interventions during the Marburg virus disease outbreak in Kagera region, Northwestern Tanzania by Mololo Noah Mwanjala, Emmanuel Mnkeni, Mikidadi Issanudia Mtalika, Marcelina Mponela, Atuganile Musyani, George Mrema, Amour Seleman, Catherine Gitige, Kokuhabwa Mukurasi, Gloria Macha, Hussein Mohamed, Pius Horumpende, Leopord Sibomana Leonard, Jonathan Mcharo, Wangeci Gatei, Salum Manyatta

“…Abstract Background Marburg virus disease (MVD) is a deadly illness caused by the zoonotic Marburg virus, which has led to outbreaks with fatality rates up to 100% in some African countries. …”
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A complete structural analysis of the FⅠ17 strike-slip fault and its hydrocarbon enrichment factors, Tarim basin, NW China by Shi Chen, Shi Chen, Xinxin Liang, Xinxin Liang, Xingguo Song, Xingguo Song, Yintao Zhang, Zhou Xie, Yuan Neng, Yuan Neng, Pengfei Kang, Jianxun Zhou, Jianxun Zhou

“…Controlled by Precambrian basement heterogeneity, the fault evolved through three stages: weak compressive stress during the Middle -Late Cambrian led to rupture along basement rifts and weak zones that formed the fault’s embryonic shape; strong compressive stress from Middle-Late Ordovician activated and propagated the fault upwards; during the Silurian-Carboniferous, the fault experienced episodic reactivation and result in the emergence of en-echelon normal faults. …”
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Evaluation of Yellow Fever Virus Infection in <i>Aedes aegypti</i> Mosquitoes from Pakistan with Distinct Knockdown Resistance Genotypes by Carlucio Rocha dos Santos, Caleb Guedes Miranda dos Santos, Dinair Couto-Lima, Bárbara Silva Souza, Rafi Ur Rahman, Marcos Dornelas Ribeiro, José Bento Pereira Lima, Ademir Jesus Martins

“…Mosquito populations have undergone strong selective pressure owing to the excessive use of insecticides. This pressure has led to the spread of alterations, such as knockdown-resistant mutations (<i>kdr</i>), which, while conferring resistance to pyrethroids, also induce various physiological side effects in the insect. …”
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Feasibility trial of STRONG: A digital intervention to improve nutritional management for individuals with esophageal and gastroesophageal junction cancer by Yu Chen Lin, Jose M. Pimiento, Jeanine Milano, Diane Riccardi, Nakesha Mckinnie, Emma Hume, Olivia Sprow, Sophia Diaz-Carraway, Mara Budnetz, Ryan Hagen, Mohammed Al-Jumayli, Allan Lima Pereira, Andrew J. Sinnamon, Ashwin Somasundaram, Jennifer B. Permuth, Amir Alishahi Tabriz, Kea Turner

“…Usability of the intervention was high, with 69 % and 92 % of participants reporting high satisfaction with tracking food intake through the Fitbit and the dietitian-led nutrition counseling sessions, respectively. …”
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Effect of Drying Methods on the Phenolic Profile and Antioxidant Capacity of <i>Pithecellobium dulce</i> (Roxb.) Benth. Aril and Its Inhibitory Properties on Human SW480 Colon Aden... by Ángel Félix Vargas-Madriz, Aarón Kuri-García, Ivan Luzardo-Ocampo, Roberto Augusto Ferriz-Martínez, Teresa García-Gasca, Carlos Saldaña, Haidel Vargas-Madriz, Salvador Horacio Guzmán-Maldonado, Jorge Luis Chávez-Servín

“…From this extract, the median lethal concentration (LC₅₀) was determined to be 13.76 mg/mL, which represents the concentration necessary to inhibit the growth of half of the cancer cells of this cell line. The extract led to cell cycle arrest in the G1 phase and an increase in apoptosis-induced cell death. …”
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