Comparative Analysis of Farm Yard Manure and NPK Fertilizer on Cabbage Yield: A Case Study of Kabale University. by Arinaitwe, Saul

“…The study clearly demonstrated that FYM (Farm Yard Manure) outperforms NPK fertilizers and a control group in enhancing key growth parameters and yield of cabbage in Kabale. FYM consistently led to a higher number of leaves, which signified its ability to promote robust vegetative growth compared to both synthetic and unfertilized conditions. …”
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An Update on African Trypanocide Pharmaceutics and Resistance. by Keneth Iceland, Kasozi, MacLeod, Ewan Thomas, Ntulume, Ibrahim, Welburn, Susan Christina

“…In humans, the development of resistance and adverse side effects against monotherapies has led to the adoption of nifurtimox-eflornithine combination therapy. …”
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Immune response profiling of HERV-W envelope proteins in multiple sclerosis: potential biomarkers for disease progression by Stefano Ruberto, Stefano Ruberto, María I. Domınguez-Mozo, M. Angel Garcıa-Martınez, Davide Cossu, Davide Cossu, Leonardo A. Sechi, Leonardo A. Sechi, Roberto Alvarez-Lafuente

“…In vitro, stimulation with pHERV-Wenv 486-504 led to a notable increase in pro-inflammatory cytokine production by CD4, CD8, and CD19 cells compared to syncytin-1env 486-500. …”
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Oligodendrocyte precursor cell-derived exosomes combined with cell therapy promote clinical recovery by immunomodulation and gliosis attenuation by Sarah Ingrid Pinto Santos, Santiago José Ortiz-Peñuela, Alessandro de Paula Filho, Ana Laura Midori Rossi Tomiyama, Lilian de Oliveira Coser, Juliano Coelho da Silveira, Daniele dos Santos Martins, Adriano Polican Ciena, Alexandre Leite Rodrigues de Oliveira, Carlos Eduardo Ambrósio

“…However, only the treatments involving EVs led to immune modulation, changing the profile from Th1 to Th2 lymphocytes. …”
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The impact of channel density, inverse solutions, connectivity metrics and calibration errors on OPM-MEG connectivity analysis: A simulation study by Shengjie Qi, Xinda Song, Le Jia, Hongyu Cui, Yuchen Suo, Tengyue Long, Zhendong Wu, Xiaolin Ning

“…Analytical variability with regard to the tested intersensor spacings, inverse solutions, and functional connectivity measures led to high result variability. Crosstalk exerted a significant impact on the accuracy, which may lead to network reconstruction failure. …”
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In Situ X-Ray Study During Thermal Cycle Treatment Combined with Complementary Ex Situ Investigation of InGaN Quantum Wells by Ewa Grzanka, Sondes Bauer, Artur Lachowski, Szymon Grzanka, Robert Czernecki, Byeongchan So, Tilo Baumbach, Mike Leszczyński

“…Heating InGaN QWs up to <i>T</i> = 1000 °C led to a simultaneous decrease in the indium content and ICDs. …”
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Contamination profile of heavy metals in marine fish and shellfish by M.A. Salam, S.C. Paul, S.N.B.M. Noor, S.A. Siddiqua, T.D. Aka, R. Wahab, E.R. Aweng

“…Rapid industrialization along with advanced agricultural activities led to the contamination in aquatic environment with heavy metals. …”
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Work ability following breast cancer – the MyHealth randomized controlled trial by Trine A. Horsbøl, Lena Saltbæk, Caroline Urhammer, Randi V. Karlsen, Christoffer Johansen, Pernille E. Bidstrup, Beverley L. Høeg, Vibeke Zoffmann, Federica Belmonte, Ingelise Andersen, Anne S. Friberg, Mads N. Svendsen, Helle G. Christensen, Vesna Glavicic, Dorte L. Nielsen, Susanne O. Dalton

“…Background and purpose: We previously demonstrated positive effects on quality of life and mental health following breast cancer when comparing a nurse-led follow-up program without scheduled visits (MyHealth) to regular follow-up. …”
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Early intervention in psychosis programs in Africa, Asia and Latin America; challenges and recommendations by Els van der Ven, Xinyu Yang, Franco Mascayano, Karl J Weinreich, Eric YH Chen, Charmaine YZ Tang, Sung-Wan Kim, Jonathan K Burns, Bonginkosi Chiliza, Greeshma Mohan, Srividya N Iyer, Thara Rangawsamy, Ralph de Vries, Ezra S Susser

“…Given the major treatment gap of early psychosis in Africa, Latin America and large parts of Asia, publicly funded, locally-led and accessible community-based EIP care provision is urgently needed. …”
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Assessing favipiravir impact on SARS-CoV-2 transmission within households: Insights from a multi-center study (FaviPrev) by Taweegrit Siripongboonsitti, Marisa Muadchimkaew, Kriangkrai Tawinprai, Ornisa Issaranon, Wichuda Meepholkij, Pureepat Arttawejkul, Apiradee Vararungzarit, Onwalee Dhissayakamol, Wilaiporn Preeyachit, Kamonwan Soonklang, Nithi Mahanonda

“…Results: Favipiravir significantly reduced household SARS-CoV-2 transmission, comparing 1836 household contacts with favipiravir-treated index cases to 170 contacts whose index cases received standard care. Favipiravir led to a 58 % secondary attack rate, substantially lower than the 71.8 % observed with standard treatment, representing a 54 % reduction in transmission likelihood, with an odds ratio of 0.46 (95 % confidence interval [CI] [0.23–0.89]). …”
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Histology Assessment of Chitosan–Polyvinyl Alcohol Scaffolds Incorporated with CaO Nanoparticles by Carlos David Grande-Tovar, Jorge Ivan Castro Castro, Lemy Vanessa Barba-Rosado, Paula A. Zapata, Daniel Insuasty, Carlos-Humberto Valencia-Llano

“…Additionally, higher CaO NPs concentrations led to a reduction in thermal properties and crystallinity. …”
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Impact of IYCF practices, as measured by national nutrition surveys from 2018 to 2022, on stunting and under-5 survival in Burkina Faso: a LiST analysis by Natacha Kere, Ella W. R. Compaore, Ella W. R. Compaore, Youssouf Keita, Daniel S. Ouedraogo, Souleymane Tirogo, Estelle A. Bambara, Z. Thierry Coulibaly, Mamoudou H. Dicko

“…The modeling results visualized in LiST were exported to Excel for formatting into tables and/or graphs.ResultsThe measured changes in the levels of infant and young child feeding interventions included in this study led to a reduction in the number of cases of chronic malnutrition in children under 6 months of age in the second scenario projections. …”
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Photodynamic Therapy with Protoporphyrin IX Precursors Using Artificial Daylight Improves Skin Antisepsis for Orthopedic Surgeries by Tiziano A. Schweizer, Julia S. Würmli, Julia Prinz, Maximilian Wölfle, Roger Marti, Hendrik Koliwer-Brandl, Ashley M. Rooney, Vanni Benvenga, Adrian Egli, Laurence Imhof, Philipp P. Bosshard, Yvonne Achermann

“…In contrast, photodynamic therapy (PDT) with red light and methyl-aminolevulinate (MAL), combined with skin antisepsis, led to the absence of bacterial growth in healthy participants, though with local skin erythema, posing an obstacle for orthopedic surgery. …”
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FTO attenuates TNF-α-induced damage of proximal tubular epithelial cells in acute pancreatitis-induced acute kidney injury via targeting AQP3 in an N6-methyladenosine-dependent man... by Xinghui Li, Qi Liang, Lu Liu, Shujun Chen, Yong Li, Yu Pu

“…Western blotting was performed to quantify β-catenin protein levels in the PTECs.Results FTO overexpression attenuated the TNF-α-induced decrease in viability and SOD levels, elevated apoptosis, increased levels of ROS and MDA, and diminished TNF-α-induced AQP3 expression and reduced β-catenin expression, but its silencing led to contradictory results. FTO negatively modulates AQP3 levels in RTECs in an m6A-depednent manner and compromises AQP3 stability. …”
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Hydrothermal conditions dominated sensitivity and lag effect of grassland productivity in Yunnan Province, China: Implications for climate change by Yan Fang, Long Wan, Jing Tong, Guijing Li, Jing Pang, Enfu Chang, Linglan Chen, Zixuan Shi

“…In contrast, warmer temperatures and water stress led to a decline in grassland productivity in the hot and dry vally of the Jinsha River. …”
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Automated diagnosis and grading of lumbar intervertebral disc degeneration based on a modified YOLO framework by Aobo Wang, Tianyi Wang, Xingyu Liu, Xingyu Liu, Xingyu Liu, Ning Fan, Shuo Yuan, Peng Du, Congying Zou, Ruiyuan Chen, Yu Xi, Zhao Gu, Hongxing Song, Qi Fei, Yiling Zhang, Yiling Zhang, Lei Zang

“…BackgroundThe high prevalence of low back pain has led to an increasing demand for the analysis of lumbar magnetic resonance (MR) images. …”
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Multicentre, randomised controlled trial to investigate the effects of parental touch on relieving acute procedural pain in neonates (Petal) by Eleri Adams, Daniel Crankshaw, Ria Evans Fry, Rebeccah Slater, Caroline Hartley, Maria M Cobo, Fiona Moultrie, Annalisa G V Hauck, Vaneesha Monk, Shellie Robinson, Marianne van der Vaart, Luke Baxter, Ravi Poorun, Aomesh Bhatt

“…Stroking of the skin can activate C-tactile fibres and reduce pain, and therefore could provide a simple and safe parent-led intervention for the management of pain. The trial aim is to determine whether parental touch prior to a painful clinical procedure provides effective pain relief in neonates.Methods and analysis This is a multicentre randomised controlled trial. …”
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Polycaprolactone for Hard Tissue Regeneration: Scaffold Design and In Vivo Implications by Fernanda Ramírez-Ruiz, Israel Núñez-Tapia, María Cristina Piña-Barba, Marco Antonio Alvarez-Pérez, Vincenzo Guarino, Janeth Serrano-Bello

“…Recently, several pathologies have led to bone loss or damage, such as malformations, bone resorption associated with benign or malignant tumors, periodontal disease, traumas, and others in which a discontinuity in tissue integrity is observed. …”
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Structure- and machine learning-guided engineering demonstrate that a non-canonical disulfide in an anti-PD-1 rabbit antibody does not impede antibody developability by Wei-Ching Liang, Hongkang Xi, Dawei Sun, Luigi D’Ascenzo, Jonathan Zarzar, Nicole Stephens, Ryan Cook, Yinyin Li, Zhengmao Ye, Marissa Matsumoto, Jian Payandeh, Matthieu Masureel, Yan Wu

“…Initial removal of the non-canonical disulfide resulted in a loss of PD-1 affinity and cross-reactivity, which led us to explore protein engineering approaches to recover these. …”
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Ecological risks in downstream lakes exacerbated by the three Gorges reservoir by Xinxin Chen, Yaxin Guo, Junhong Zhang, Xiao Han, Weiya Huang, Yao Yue

“…The results showed that (1) TGD storage led to a decrease in the number of high pulses at downstream stations, resulting in wetland degradation in the riverine region; (2) the SI (Shannon’s diversity index) based on hydrological calculations became smaller, indicating that the downstream biodiversity showed a decreasing trend; (3) the diversion ratio and the confluence ratio of Dongting Lake and the Yangtze River decreased at the same time, and the connectivity decreased, which would lead to an increase in the degree and frequency of droughts during the dry season;(4) after the regulation of the TGD, the low-risk months were transformed into medium-risk months of the Dongting Lake basin, indicating a deterioration of the ecological situation in this region. …”
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