An algorithm for infectious screening of corneal donors in eye tissue bank of the Fyodorov Eye Microsurgery Federal State Institution by S.A. Borzenok, M.Yu. Gerasimov, Yu.A. Komakh, M.Kh. Khubetsova, H.D. Tonaeva, L.M. Malikova, P.I. Plaksa

“…Overall, the positive serology and hemolysis were the major contraindications and led to exclusion 33.4% (n=1162) of incoming corneas in the ETB. …”
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Duckweed: a starch-hyperaccumulating plant under cultivation with a combination of nutrient limitation and elevated CO2 by Ling Guo, Ling Guo, Yang Fang, Songhu Wang, Yao Xiao, Yanqiang Ding, Yanling Jin, Xueping Tian, Anping Du, Zhihua Liao, Kaize He, Shuang Chen, Yonggui Zhao, Li Tan, Zhuolin Yi, Yuqing Che, Lanchai Chen, Jinmeng Li, Leyi Zhao, Peng Zhang, Zhengbiao Gu, Fangyuan Zhang, Yan Hong, Qing Zhang, Hai Zhao

“…Moreover, while nitrogen redistribution was increased, sucrose biosynthesis and transportation and lignocellulose biosynthesis were reduced. These alterations led to a reduction in lignocellulose and protein contents and ultimately an increase in the accumulation of starch in the chloroplasts.ConclusionThis work demonstrates the potential of duckweed as a highly efficient starch producer.…”
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Revealing the mismatch in the response to warm-wetting climate of vegetation greenness and primary productivity using MODIS GPP/LAI in Nepal by Dongping Zhong, Lingwen Zeng, Ye Chen, Yingdong Tong, Nana Bai, Jia Sun, Dongdong Zhang, Yingchun Fu

“…And the decreased temperature and precipitation had negative impacts on treeline deviation, which led to spatial variations in treeline deviation and coupling degree on either side of the 83°E in the Nepalese Himalayan alpine forests. …”
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Protein tyrosine phosphatase delta is a STAT3-phosphatase and suppressor of metabolic liver disease by Thomas F Baumert, Charlotte Bach, Patrick Pessaux, Catherine Schuster, Frank Jühling, Sarah C Durand, Yujin Hoshida, Fabien Zoulim, Atish Mukherji, Naoto Fujiwara, Marine A Oudot, Armando Andres Roca Suarez, Michel L Tremblay, Barbara Testoni, Joachim Lupberger, Romain Parent, Laurent Mailly, Nassim Dali-Youcef, Emanuele Felli, Maria Saez-Palma, Julien Moehlin, Alessia Virzì, Nicolas Brignon, Eugenie Schaeffer, Romain Martin, Laura Meiss-Heydmann, Zakaria Boulahtouf, Lea Girard, Emma Osswald, Carole Jamey, Daniel Brumaru, Bhuvaneswari Koneru

“…During MASH, low PTPRD led to increased liver steatosis in Ptprd+/− mice and a pronounced unfolded protein response, which impacts insulin signalling. …”
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Acute Myocardial Infarction Reduces Respiration in Rat Cardiac Fibers, despite Adipose Tissue Mesenchymal Stromal Cell Transplant by Camila I. Irion, Eduarda L. Martins, Michelle L. A. Christie, Cherley B. V. de Andrade, Alan C. N. de Moraes, Raphaela P. Ferreira, Cibele F. Pimentel, Grazielle D. Suhett, Antonio Carlos C. de Carvalho, Rafael S. Lindoso, Adalberto Vieyra, Antonio Galina, Regina C. S. Goldenberg

“…All these alterations in mitochondrial respiration were still present in the group treated with AD-MSC. In conclusion, AMI led to mitochondrial dysfunction with oxidative phosphorylation disorders, and AD-MSC improved CS temporarily but was not able to avoid alterations in mitochondria function over time.…”
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Protocol for a prospective observational cohort study of cutaneous leishmaniasis in Ethiopia [version 2; peer review: 2 approved, 1 approved with reservations] by Fewzia Shikur Mohammed, Amel Beshir Mohammed, Shimelis Doni Nigusse, Feleke Tilahun Zewdu, Abebaw Yeshambel Alemu, Teklu Cherkose, Kidist Bobosha, Eshetu Molla, Iris Mosweu, Vanessa Yardley, Saba Maria Lambert, Mirgissa Kaba, Endalamaw Gadisa, Yohannes Hailemichael, Catherine Pitt, Elizabeth Allen, Stephen L. Walker, Michael Marks

“…This will help improve evidence-based guidelines and support evidence-led policy decisions, not only in Ethiopia but also globally.…”
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Understanding the dynamics driving obesity in socioeconomically deprived urban neighbourhoods: an expert-based systems map by Fleur ter Ellen, Joost Oude Groeniger, Karien Stronks, Luc L. Hagenaars, Carlijn B.M. Kamphuis, Joreintje D. Mackenbach, Mariëlle A. Beenackers, Karen Freijer, Pieter Coenen, Maartje Poelman, Karen M. Oude Hengel, Frank J. van Lenthe

“…In turn, these dynamics led to the emergent result of rising obesity prevalence in socioeconomically deprived urban neighbourhoods over the past decades. …”
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Effects of Artemisia argyi leaf water extract (AWE) on growth performance, muscle quality, intestinal microbial, and metabolomics of common carp (Cyprinus carpio) by Di Sun, Nanyang Zeng, Yingjia Pan, Qingsong Shu, Jixing Zou, Yingshi Huang, Guoxia Wang, Jun Shi

“…Notably, treatment with A1 significantly enhanced the growth performance of carp while increasing body fat content and reducing protein levels (p < 0.05). Furthermore, A1 led to a significant increase in intestinal villi length (p < 0.05) and a reduction in liver fat deposition levels. …”
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Fungal Submerged Fermentation of Coffee Silverskin: A Sustainable Source of Natural Meat Additives by Stephany Carolina Terán-Rivera, Gastón Ramón Torrescano-Urrutia, Brisa del Mar Torres-Martínez, Martín Esqueda-Valle, Félix Joel Ibarra-Arias, Armida Sánchez-Escalante, Rey David Vargas-Sánchez

“…Regarding pork meat homogenate treated with ME and FE extracts and subjected to oxidation with potassium ferrocyanide, results demonstrated that inclusion of FE-obtained extract led to decreased pH, lipid oxidation, metmyoglobin, and color changes (L*, a*, b*, C*, and h*), and microbial growth. …”
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Insight into the role of antioxidant in microbial lignin degradation: Ascorbic acid as a fortifier of lignin-degrading enzymes by Aipeng Li, Weimin Wang, Shuqi Guo, Changzhi Li, Xinying Wang, Qiang Fei

“…Furthermore, the addition of AA led to a reduction in the molecular weights of lignin and an increase in the content of degradation products with lower molecular weight, indicating more thorough degradation of lignin. …”
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NCAPD3‐mediated AKT activation regulates prostate cancer progression by Yi Zhang, Wanlin Xie, Xicui Zong, Yuanyuan Fang, Jia Ren, Zuolei Jing, Yong Wei, Shan Lu, Qingyi Zhu, Ping Liu

“…NCAPD3 increased STAT3 expression and phosphorylation in PCa cells, thereby enhancing STAT3 transcriptional activity to improve the levels of JAK2 and EZH2. This led to an increase in phosphorylation of AKT at Thr 308 and Ser 473 through JAK2/PI3K and EZH2/NSD2/mTORC2 pathways, respectively. …”
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Transitioning to a virtual post-intensive care rehabilitation service in response to the COVID-19 pandemic: results of multidisciplinary focus-groups by Fiona Howroyd, Fiona Howroyd, Natacha Earle, Jonathan Weblin, David McWilliams, Mark Raven, Niharika A. Duggal, Zubair Ahmed, Zubair Ahmed, Tonny Veenith

“…Semi-structured questions were used to guide discussions, led by a facilitator and scribe. Transcripts were thematically analysed using an exploratory inductive approach by two researchers then crosschecked.FindingsThree focus groups were attended by 12 multidisciplinary stakeholders, including six physiotherapists, two administration staff members, two critical-care follow-up nurses and two critical care consultants. …”
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Dynamic balance control in healthy young women during stair descent: a plantar pressure-based study by Ruiqin Wang, Ruiqin Wang, Jinfeng Cao, Haoran Xu, Panjing Guo, Yumin Li, Yuyi Fan, Yunfei Gui, Leqi Li, Roger Adams, Jia Han, Jia Han, Jia Han, Jie Lyu, Jie Lyu

“…There was no significant difference in the kinematic parameters of plantar pressure during stair descent, regardless of whether the dominant foot or non-dominant foot was the leading foot.ConclusionThis study found that among young women, an increase in step height during descent significantly affected the plantar pressure and led to greater COP adjustment in the directions of ML and AP, increasing the risk of injury. …”
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Dual targeting of breast cancer by chitosan/poly lactic-co-glycolic acid nanodelivery systems: Surface activation with folic acid/aptamers, and co-encapsulated with Sorafenib and q... by Asghar Narmani, Saeid Ganji, Maryam Amirishoar, Fatemeh Hajikarimi, Aynaz Mazandarani, Mahya Karimi, Ali Mohammadinejad, Azin Azadpour, Roghayyeh Jahedi, Elham Assadpour, Seid Mahdi Jafari

“…Also, this nanocarrier led to > 90% proptosis and > 10- and 11.5-fold enhancement in SOD and catalase values in MCF-7 cells. …”
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Unraveling the pathogenesis of Barrett’s esophagus and esophageal adenocarcinoma: the “omics” era by Alberto Barchi, Giuseppe Dell’Anna, Giuseppe Dell’Anna, Luca Massimino, Luca Massimino, Francesco Vito Mandarino, Edoardo Vespa, Edi Viale, Sandro Passaretti, Vito Annese, Vito Annese, Alberto Malesci, Alberto Malesci, Silvio Danese, Silvio Danese, Federica Ungaro

“…Epigenetic alterations (such as hyper or hypo-methylation) play a meaningful role in esophageal carcinogenesis as well as the study of the tumor micro-environment, which has led to the development of novel immunological therapeutic options. …”
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Land use intensity differently influences soil communities across a range of arable fields and grasslands by Chenguang Gao, Johanna E.M. Schild, Gabriel Y.K. Moinet, T. Martijn Bezemer, Franciska T. de Vries, Jan Hassink, Nick van Eekeren, Kevin Beentjes, Peter M. van Bodegom

“…Furthermore, an increase in land use intensity led to greater soil network complexity in arable fields.Our findings reveal regional on-farm patterns of land use intensity effects on various soil communities and identified key agricultural practices that structure soil communities. …”
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The Addition of Pumpkin Flour Impacts the Functional and Bioactive Properties of Soft Wheat Composite Flour Blends by Durim Alija, Remigiusz Olędzki, Daniela Nikolovska Nedelkoska, Agata Wojciechowicz-Budzisz, Gafur Xhabiri, Ewa Pejcz, Eljesa Alija, Joanna Harasym

“…Growing interest in functional food ingredients has led to the exploration of pumpkin flour as a nutritional enhancer in wheat-based products. …”
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Premorbid and current intellectual performance reflects different backgrounds in patients with Parkinson's disease by Hidetomo Murakami, Machiko Kezuka, Junnosuke Ozawa, Kaoru Matsuoka, Tatsuya Nakanishi, Atsushi Ishida, Naohito Ito, Mizuki Kanemoto, Mitsuru Kawamura

“…Spearman correlation coefficients were calculated for background factors (current age, years of education, UPDRS Part III, and levodopa equivalent dose of prescribed drugs (LED)) with MoCA scores and estimated IQs. Results: Estimated VIQ (r = 0.451, p = 0.001), PIQ (r = 0.445, p = 0.002) and FIQ (r = 0.453, p = 0.001) were significantly correlated with years of education that was fixed until adolescence (i.e. 20 s). …”
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Heightened demand for mental health information resources during the SARS-CoV-2 pandemic in Germany: A retrospective longitudinal analysis of helpline calls by Jil Zippelius, Simon Schreynemackers, Ulrich Hegerl, Hanna Reich

“…Background: The SARS-CoV-2 pandemic precipitated disruptions and limitations in medical services which led to changes in help-seeking behaviour. There was a surge the demand for crisis hotlines. …”
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Vision Sensor for Automatic Recognition of Human Activities via Hybrid Features and Multi-Class Support Vector Machine by Saleha Kamal, Haifa F. Alhasson, Mohammed Alnusayri, Mohammed Alatiyyah, Hanan Aljuaid, Ahmad Jalal, Hui Liu

“…Over recent years, automated Human Activity Recognition (HAR) has been an area of concern for many researchers due to its widespread application in surveillance systems, healthcare environments, and many more. This has led researchers to develop coherent and robust systems that efficiently perform HAR. …”
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