De Novo Genome Assembly for an Endangered Lemur Using Portable Nanopore Sequencing in Rural Madagascar by Lindsey Hauff, Noa Elosmie Rasoanaivo, Andriamahery Razafindrakoto, Hajanirina Ravelonjanahary, Patricia C. Wright, Rindra Rakotoarivony, Christina M. Bergey

“…While the advent of next‐generation sequencing technologies and the resulting reduction in associated costs have led to the proliferation of genomic data and high‐quality reference genomes, global discrepancies in genomic sequencing capabilities often result in biological samples from biodiverse host countries being exported to facilities in the Global North, creating inequalities in access and training within genomic research. …”
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Advancing dynamic quantum crystallography: enhanced models for accurate structures and thermodynamic properties by Helena Butkiewicz, Michał Chodkiewicz, Anders Ø. Madsen, Anna A. Hoser

“…Advancements in theory, experimental techniques, diffractometers and detection technology have led to the acquisition of highly accurate diffraction patterns, surpassing previous expectations. …”
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Validation of the detection of elder abuse through emergency care technicians (DETECT) screening tool: a study protocol by Melvin D Livingston, Brad Cannell, Julie Weitlauf, Jason Burnett, Megin Parayil, Jennifer Reingle Gonzalez

“…Follow-up interviews will consist of a medic-led semistructured interview designed to assess the older adult’s likelihood of abuse exposure, physical/mental health status, cognitive functioning, and to systematically evaluate the quality and condition of their physical and social living environment. …”
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Study of the impact on emissions and engine performance of diesel fuel additives made from cotton and castor blended seed oils by Hailegebrel Zewdie Woldetensy, Dinku Seyoum Zeleke, Getachew Shunki Tibba

“…The higher oxygen content of biodiesel significantly reduced CO emissions, however higher oxygen percentages in blends of biodiesel led to a rise in CO2 emissions. Because cotton and castor blended additives ignited more quickly, NOx increased. …”
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Trends in psychiatric emergency visits: insights from France’s largest psychiatric emergency department by Marine Ambar Akkaoui, David Barruel, Valérie Dauriac-Le Masson, Raphael Gourevitch, Alexandra Pham-Scottez

“…Abstract Introduction Psychiatric emergency departments (EDs) in France have been under pressure from several factors, exacerbated by the COVID-19 pandemic. The pandemic led to an increase in psychiatric disorders, particularly anxiety and depression, with younger people and women being most affected. …”
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Optimization of the Offshore Wind Turbines Layout Using Cuckoo Search Algorithm by Ibrahim Abdulwahab, Solomon Andrew Onazi, Gideon Rimamfate, Akande Abdulwasiu, Abubakar Umar, N.A Iliyasu

“…Developing effective means of optimizing wind farm configurations is a major concern for energy communities. This has continuously led to increased power generation and a corresponding cost reduction. …”
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Impact of strict IGF1 control on quality-of-life scores in patients with acromegaly by Chaitanya Gandhi, Marie-Claire Denis, Daniel Holmes, Juan Rivera, Stan van Uum, Shereen Ezzat, Constance Chik

“…Hemoglobin A1c and liver enzymes did not differ and repeat MRI of the sella at 6 months showed no change.ConclusionsIn this pilot study, stricter control of modest IGF1 elevations led to symptomatic improvement as measured by the PASQ score. …”
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Exploring the experiences of children's palliative care for forced migrant families in the United Kingdom: an interpretative phenomenological study by Marie Clancy, Caroline Bradbury-Jones, Jenny Phillimore, Julie Taylor

“…However, barriers included poor access to services and resources, protocol-led care, limited time with families, communication barriers and staff burnout.DiscussionThe findings suggest the need for a specific educational pathway for palliative care professionals to include spiritual care provision, cultural humility, and moral reasoning. …”
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High-quality DNA extraction for Desmodium gangeticum: A medicinal shrub of Shivalik Himalayas by Shiwani Singh, Maneesh S. Bhandari, Neeraj Dwivedi

“…Conclusion: This standardised buffer condition and protocol led to high-quality DNA isolation, which was found good for restriction digestion using endonuclease enzymes, PCR and other molecular biology techniques, highlighting the ongoing efforts to enhance the reliability of genetic studies in medicinal plants. …”
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Integrative physiological and transcriptome analysis unravels the mechanism of low nitrogen use efficiency in burley tobacco by Yuqing Feng, Yuanyuan Zhao, Yanjun Ma, Xiaolong Chen, Hongzhi Shi

“…Less advantageous changes in nitrogen uptake, nitrogen assimilation in combination with nitrogen remobilization, and maintenance of photosynthesis in response to nitrogen deficiency led to a lower NUE in TN90. The key genes (TPIP1, GAPB, PGK3, PSBO, PSBP2, PSAG, and GLN2) were associated with improving photosynthesis and nitrogen metabolism in tobacco plants grown under N‐deficient conditions.…”
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Continuous atrial fibrillation monitoring using a wearable smartwatch: Using long-term Holter as reference by Yannan Pan, Erdong Chen, Shihui Jie, Dongbo Huo, Zhongru Ding, Jing Zhou, Jie Jiang, Jianping Li, Yong Huo

“…Susceptibility to false positives led to modest specificity. Smartwatch performances were affected by AF durations and time periods. …”
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HSPB1 Regulates Autophagy and Apoptosis in Vascular Smooth Muscle Cells in Arteriosclerosis Obliterans by Keqin Chen, Changmiao Hou, Lei Xu, Hanwu Peng, Chaogui He, Jing Liu, Guoqing Wang, Shaoshuai Huang, Xiehong Liu

“…Overexpression of HSPB1 promoted apoptosis of VSMCs following ox-LDL treatment. Knockdown of HSPB1 led to a marked increase in the expression of LC3II and Beclin-1 in ox-LDL-stimulated VSMCs, whereas knockdown of HSPB1 attenuated these changes (p<0.05). …”
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Assessing the industry 4.0 strategies for a steel supply chain: SWOT, game theory, and gap analysis by Sima Motallebi, Mostafa Zandieh, Akbar Alem Tabriz, Erfan Babaee Tirkolaee

“…The recent adoption of modern technologies has led to the fourth industrial revolution or Industry 4.0 (I4.0). …”
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False Alarm Causes and Wind Field Sensitivity Analysis of a Severe Rainfall Event in the Guangdong-Hong Kong-Macao Greater Bay Area Urban Cluster by Lan Zhang, Jiawen Zheng, Huaiyu Li, Rui Yu, Lei Wei, Yufei Zhang

“…The results indicate that the warm and moist airflow transported by the low-level jet stream was intercepted by the upstream MCS (mesoscale convective system) along the coastal area of western Guangdong, and inadequate conditions of negative vorticity dynamics led to insufficient moisture, thermodynamic, and dynamic conditions over the urban cluster, preventing the triggering of heavy precipitation. …”
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A Contemporary Analysis of Discharge Disposition Following Total Joint Arthroplasty by Swaroopa Vaidya, MS, Gregory Panza, PhD, Jake Laverdiere, BS, Dianne Vye, MSN, RN, ONC, Jenna Bernstein, MD

“…Discharge to a skilled nursing facility (SNF) remains a primary driver of post-acute care costs. The COVID-19 pandemic led to a decrease in number of discharges to SNFs. …”
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Media content analysis of general practitioners’ reactions to care.data expressed in the media: what lessons can be learned for future NHS data-sharing initiatives? by Srinivasa Vittal Katikireddi, Andy Boyd, Elizabeth Ford, Yalda Kazempour, Maxwell J F Cooper

“…They distrusted the government’s likely uses of the data and perceived a risk of patient reidentification if the data were sold onto commercial entities.Conclusions Findings show specific concerns which GPs had about care.data which led to the withdrawal of support. Future NHS patient data-sharing schemes should engage with GPs and other clinicians as key stakeholders from the earliest moments of planning, so that their views and needs are incorporated into the design of such schemes.…”
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Estimation of TP53 mutations for endometrial cancer based on diffusion-weighted imaging deep learning and radiomics features by Lei Shen, Bo Dai, Shewei Dou, Fengshan Yan, Tianyun Yang, Yaping Wu

“…Results Compared to the DL (AUCtraining = 0.830, AUCtest = 0.779, and AUCvalidation = 0.711), radiomics (AUCtraining = 0.810, AUCtest = 0.710, and AUCvalidation = 0.839), and clinical (AUCtraining = 0.780, AUCtest = 0.685, and AUCvalidation = 0.695) models, the combined model based on the GP algorithm, which consisted of four DL features, five radiomics features, and two clinical variables, not only demonstrated the highest diagnostic efficacy (AUCtraining = 0.949, AUCtest = 0.877, and AUCvalidation = 0.914) but also led to an improvement in risk reclassification of the TP53 mutation (NIRtraining = 66.38%, 56.98%, and 83.48%, NIRtest = 50.72%, 80.43%, and 89.49%, and NIRvalidation = 64.58%, 87.50%, and 120.83%, respectively). …”
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Assessment of Cognitive Functions in Multimorbid Patients in Lithuanian Primary Care Settings: A Cross-Sectional Study Using MMSE and LT-GPCOG by Silvija Valdonė Alšauskė, Ingrida Grabauskytė, Ida Liseckienė, Jūratė Macijauskienė

“…<i>Background and Objectives</i>: The aging population has led to a rise in cognitive impairments, including dementia, often associated with multimorbidity. …”
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Investigating the Effect of Testosterone Supplement on Heart and Muscle Damage in Rats Applied with Swimming Exercise by Ömer Kulaksız, Sefa Lök

“…Because testosterone production is naturally increased in the body during the exercise, swimming exercise and testosterone administration led to significant occurrence of troponin I, ck-MB, LDH, which are heart damage indicators in rats, and CK value, which is an indicator of muscle damage, in the blood. …”
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The incidence of venous thromboembolism is low when risk stratification-based thromboprophylaxis is used after fast-track hip and knee arthroplasty by Annette M Moisander, Konsta Pamilo, Jukka Huopio, Hannu Kautiainen, Anne Kuitunen, Juha Paloneva

“…Fast-track protocols have improved patient care and led to shorter immobilization and length of stay (LOS) after THA and TKA, thereby diminishing venous thromboembolism (VTE) risk. …”
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