Determining the alignment of assessment items with curriculum goals through document analysis by addressing identified item flaws by Humaira Fayyaz Khan, Shazia Qayyum, Huma Beenish, Rehan Ahmed Khan, Samina Iltaf, Lubna Rani Faysal

“…The latter category was recognized as “alignment flaws” which was not previously documented.The documentation and rectification of these flaws, which included issues such as misaligned learning objectives, incorrect assessment strategies, and disconnects between scenarios and lead-ins, led to their inclusion in the institutional checklist, facilitating ongoing improvements in assessment quality. …”
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Computational analysis of congenital heart disease associated SNPs: unveiling their impact on the gene regulatory system by Shikha Vashisht, Costantino Parisi, Cecilia L. Winata

“…To study the functional implications of noncoding CHD-SNPs, we cross-validated them with enhancer-specific histone modification marks from developing human heart across 9 Carnegie stages and identified potential cardiac enhancers. This approach led to the identification of 2,056 CHD-associated putative enhancers (CHD-enhancers), 38.9% of them overlapping with known enhancers catalogued in human enhancer disease database. …”
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Anticancer Activity of Holothuria Leucospilota-Derived Saponin on MKN45 Gastric Cancer Cell via Upregulation of CDH1 Hub Gene by Khadijeh Sadegh, Amirhossein Ahmadi, Ahmad Shadi, Ahmad Ghasemi

“…Comparisons between groups were performed using the ANOVA test by GraphPad Prism software at the statistically significant P-value <0.05.Results: HLBS with an IC50 concentration of 75 μg/ml at 48 hours resulted in a significant decrease in cell viability, clonogenic ability (46.63% reduction, P < 0.01), and migration of MKN45 cells (74.5% reduction, P < 0.01). Moreover, HLBS led to an increase of approximately 21 and 13% in the S-phase and apoptotic cell populations, respectively. …”
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Evaluating Avacopan in the Treatment of ANCA-Associated Vasculitis: Design, Development and Positioning of Therapy by van Leeuwen JR, Quartuccio L, Draibe JB, Gunnarson I, Sprangers B, Teng YKO

“…Here, we review the clinical trials that have led to demonstrate that avacopan is an effective treatment option in the management of AAV, where it can significantly reduce the cumulative dosage of glucocorticoids (GC). …”
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Innovations and innovative in domestic banking: Theoretical aspect by Natalia Mostovenko

“…However, the effect of the introduction of innovations and the growth of the role of the service sector led to the fact that innovations became the driver of the formation of new consumer properties not only of goods, but also of services. …”
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Optimization of Dyeing Conditions of Natural Dye Obtained from Vaccinium corrymbosum (Blueberry) On Cotton Fabric by Yahaya Musa Abubakar, Fatima Garba, Ma’aruf Abdulmumin Muhamad, Yilni Edward Bioltif, Ansar Bilyamin Adam, Lawan Usman

“…The study found that increasing dye concentration led to greater dye absorption by the fabric. As temperature increased from 60 to 90 °C, dye molecule movement accelerated, enhancing diffusion into the fiber structure and resulting in deeper, more intense coloration. …”
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Impact of electronic AKI alert/care bundle on AKI inpatient outcomes: a retrospective single-center cohort study by Michael Chen-Xu, Christopher Kassam, Emma Cameron, Szymon Ryba, Vivian Yiu

“…Median LOS was longer when the AKI order set was utilized than when not (11.8 versus 8.8 days, p < .001), but was independently associated with improvement in the AKI stage (28.9% versus 8.7%, p < .001; univariable OR 4.25, 95% CI 3.53–5.10, multivariable OR 4.27, 95% CI 3.54–5.14).Conclusions AKI order set use led to improvements in all-cause mortality and renal function, but longer LOS, among AKI patients at WSH.…”
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The development process of a type 2 diabetes health-promoting CBPR intervention by Cecilia Lindsjö, Katarina Sjögren Forss, Christine Kumlien, Anders Kottorp, Margareta Rämgård

“…The partnership process made it possible to involve relevant collaborators, which resulted in a jointly developed nurse-led educational intervention. Participants and stakeholders were also involved in the process of modifying and elaborating evaluation tools appropriate for the intervention.Discussion/conclusionsThe community-based participatory research approach enables the acknowledgement and use of the various kinds of knowledge of all stakeholders, including the community members. …”
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The Effect of Contraceptive Pills on the Severity of Visceral Leishmaniasis by Measuring Some Physiological Parameters by Hanan F. Ghazi, Sabaa T. Mohammed, Areej A. Zabbon, Mohamed Tawfiek Shaaban

“…Results: The results showed that the OC led to a significant increase in all indicators in the third week, which is compared with the drug group pentostam group, Data expressed as mean ± SD and values of ( P>0.05) were considered statically nonsignificant, while (P<0.05) and (P<0.01) were considered significantly different, highly significantly different, respectively. …”
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The Impact of (DEM) Accuracy and (LC/LU) Resolution on the Watersheds Areas by Alaa Qais Muttar, Mustafa Tariq Mustafa, Muntasir Abdl Hameed Abdl Shareef

“…Analysis of the results led to the finding that Copernicus DEM (GLO-30) 30 m spatial resolution is the most accurate and optimum DEM in the research study area with 1.1615 m vertical accuracy and 2.276 m at 95% confidence level. …”
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Exploring trust in religious leaders and institutions as a mechanism for improving retention in child malnutrition interventions in the Philippines: a retrospective cohort study by Lincoln Leehang Lau, Warren Dodd, Han Lily Qu, Donald C Cole

“…Retention in the programme led to improved WHZ among participating children (−0.38 (95% CI: −1.43, 0.26)). …”
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Assessing the effect of empathy-enhancing interventions in health education and training: a systematic review of randomised controlled trials by Nia Roberts, Jeremy Howick, Eyad Issa, Rachel Winter, Robert I Norman

“…Further high-quality trials are needed that include patient-led outcome assessments and further evaluate the long-term sustainability of empathy training.Protocol registration number PROSPERO (CRD42019126843).…”
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Do The Facts of Voting Rights Support Chief Justice Roberts’s Opinion in Shelby County? by Morgan Kousser

“…Based on the largest database of voting rights “events” – successful lawsuits, Section 5 Justice Department objections and “more information requests,” and consent decrees or settlements out of court that led to pro-minority changes – ever compiled, this paper provides a unique overview of the history of U.S. voting rights from 1957, when the first U.S. civil rights law in 82 years passed, through 2013. …”
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Functional Improvements by Controlled Suture Tension in Arthroscopic Rotator Cuff Repair by Shinji Imai, MD, PhD

“…Double-row suture-bridge repairs with fixed, low tension led to superior clinical outcomes at 6 months and a superior tendon healing rate at 1 year compared with repairs with higher suture tension. …”
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Aqueous Extract of Leaves and Flowers of Acmella caulirhiza Reduces the Proliferation of Cancer Cells by Underexpressing Some Genes and Activating Caspase-3 by Huiny Miriane Tienoue Fotso, Mary-Ann Mbong Angie, Françoise Raïssa Ntentie, Inelle Makamwe, Ferdinand Lanvin Edoun Ebouel, Emmerencia Kenjing Ndansack, Enyong Julius Oben

“…The increasing prevalence of cancers and the multiple side effects of cancer treatments have led researchers to constantly search for plants containing bioactive compounds with cell death properties. …”
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Exploring purine analogues as inhibitors against Katanin, a microtubule severing enzyme using molecular modeling approach by Vibhuti Saxena, Pruthanka Patil, Purva Khodke, Bajarang Vasant Kumbhar

“…A total of 276,280 purine-type compounds from the PubChem database were subjected to structure-based high-throughput virtual screening, followed by ADME prediction, PASS analysis, and molecular docking studies. These efforts led to the identification of two potent compounds: PubChem CID 122589735 and 123629569, which demonstrated strong binding interactions with katanin. …”
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The utility of Glaucoma Information Cards for grasping glaucoma subtypes: a single-center pilot study by Yukinori Yamada, Tetsuya Murase, Emiko Mashida, Yuki Kakeda, Yuuka Shibata, Hiroaki Matsuo

“…The contraindication in patients with open-angle glaucoma (OAG) led to excessive medication restrictions because anticholinergic drugs are associated with a low risk of acute glaucoma attacks in OAG. …”
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A War Tactician: K̲h̲ālid b. al-Walīd by Hüseyin Gökalp

“…K̲h̲ālid was an extraordinary warrior and commander who lived in 7th century and led Muslim armies against Romans and Sassanids. …”
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Theoretical Cognition and Practical Design of a High-Quality Teacher Education System for Building a Country Strongin Education: An Interview with Professor Liu Haimin from Northea... by LIU Haimin, MAN Ying

“…Following the introduction of the discourse on high-quality development in the field of economy, Professor Liu led his team to pioneer research on high-quality education development, and was successively approved fortwo major projects funded by the National Social Science Fund of China, namely"Research on the Paths and Countermeasures for the High-Quality Development of Chinese Education in the New Era"and "Research on the Connotation, Comparison, and Construction Paths of a High-Quality Education System". …”
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The Safety and Efficacy of Lansoprazole plus Metoclopramide among Neonates with Gastroesophageal Reflux Disease Resistant to Conservative Therapy and Monotherapy: A Clinical Trial by Peymaneh Alizadeh Taheri, Elahe Validad, Kambiz Eftekhari

“…The combination of each acid suppressant with metoclopramide led to a higher response rate in comparison with monotherapy used before intervention. …”
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