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6601
Anger Emotional Stress Influences VEGF/VEGFR2 and Its Induced PI3K/AKT/mTOR Signaling Pathway
Published 2016-01-01“…Anger emotional stress led to abnormal expression of VEGF/VEGFR2 mRNA and protein and disorderly expression of key factors in the PI3K/AKT/mTOR signal pathway. …”
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6602
Cardiac CT reveals high prevalence of coronary artery disease in esophageal cancer eligible for radiotherapy
Published 2025-02-01“…Background: Assessment of cardiac disease before cancer therapy is crucial, as advancements in cancer treatment have led to prolonged survival and an increase in cardiovascular complications. …”
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6603
Alternative buffer systems in biopharmaceutical formulations and their effect on protein stability
Published 2024-09-01“…Conversely, freeze-thaw stress led to a significant increase in aggregate formation in tested formulations, highlighting the efficacy of several alternative buffers, particularly arginine/ citrate, in preserving protein stability. …”
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6604
Titanium dioxide -mediated regulation of enzymatic and non-enzymatic antioxidants, pigments, and diosgenin content promotes cold stress tolerance in Trigonella foenum-graecum L.
Published 2025-01-01“…Simultaneous exposure to cold stress and TiO2 NPs led to a substantial increase in diosgenin content, with the upregulation of SEP, SQS, CAS, and SSR genes compared to control conditions. …”
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6605
Nonlinear optical response of thermally stable perovskite for near-infrared optical modulator
Published 2025-01-01“…Metal halide perovskite has generated significant attention due to its high optical absorption coefficient, the tunability of bandgap, and its solution processing properties, all of which have led to a range of applications including solar cells, photodetectors, light-emitting diodes and lasers. …”
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6606
Sigma-1 Receptor Modulates CFA-Induced Inflammatory Pain via Sodium Channels in Small DRG Neurons
Published 2025-01-01“…Our results revealed several key findings: (1) The expression of Sig-1R was found to be upregulated during the progression of inflammatory pain, with a notable translocation from the cytoplasm to the membrane; (2) Inhibition of peripheral Sig-1R using S1RA resulted in a reduction of CFA-induced allodynia; (3) Activation of Sig-1R through PRE-084 led to a decrease in the fast sodium current in isolated DRG neurons from CFA-treated rats, which was associated with a diminished action potential (AP) peak and maximum depolarizing rate (MDR), as well as an increased rheobase; (4) Furthermore, PRE-084 was observed to enhance the slow component of the sodium current, resulting in hyperpolarization of the threshold potential and an increase in AP firing frequency, alongside an elevation in the mRNA expression of the slow sodium channel Nav1.9 in CFA-treated rats. …”
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6607
Age, creatinine, and ejection fraction score is a risk factor for acute kidney injury after surgical aortic valve replacement
Published 2025-12-01“…After dividing ACEF into quartiles, each one-unit increment in ACEF led to a 2.27-fold risk in the incidence of AKI among patients.Conclusions AKI is a generalizable phenomenon occurring frequently after SAVR. …”
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6608
Diversity and Plant Growth-Promoting Properties of <i>Rhodiola rosea</i> Root Endophytic Bacteria
Published 2024-12-01“…Screening for functional genes related to the nitrogen cycle, phosphorus mineralisation or dissolution, and traits associated with nitrogen fixation (56% of isolates), siderophore production (40%), inorganic phosphorus solubilisation (30%), and production of indole-related compounds (51%) led to the classification of the isolates into 16 distinct clusters. …”
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6609
A Model for Implementing New FinTechs in the Banking Industry (Peer-to-Peer Lending)
Published 2024-06-01“…All these factors have led to the decrease in the popularity of the banking system; But on the other side of the field, the increase of people who, for various reasons, cannot use traditional banking services or do not want to use them, has led to the development of fintechs. …”
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6610
Distinct expression profile reveals glia involvement in the trigeminal system attributing to post-traumatic headache
Published 2024-11-01“…Results The repetitive impacts at the bregma, but not pre-bregma site led to periorbital hypersensitivity, which was correlated with enhanced inflammatory gene expression in multiple brain regions. …”
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6611
Mechanical and microstructural characterization of graphene reinforced Alumina Ceramic matrix composite
Published 2025-03-01“…The results indicated that increased graphene content led to a reduction in Vickers hardness, but flexural strength and fracture resistance initially enhanced, reaching a maximum for 0.5 wt%, before decreasing at elevated concentrations. …”
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6612
Gonadal health benefits of black cumin (Nigella sativa) seed oil on chronic lead-exposed male Wistar rats
Published 2025-03-01“…The findings indicated a significant drop in serum concentrations of testosterone and thyroxin (T4) in Pb-exposed rats, whereas NSO demonstrated a remarkable ability to restore these hormone levels. Moreover, Pb exposure led to a notable reduction in sperm motility, sperm concentration, testis weight, and testis diameter, accompanied by seminiferous tubule degeneration. …”
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6613
Elevated Liver Function Tests as Predictors of Severe Maternal Outcomes in Women with Preeclampsia
Published 2025-01-01“… Background: Preeclampsia is a hypertensive disorder of pregnancy that ultimately led to high mortality and morbidity due to its complication HELP (Hemolysis, Elevated Liver Enzymes, and Low Platelet count), syndrome, and its association with elevated liver function tests. …”
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6614
The ability of layered double hydroxides for nitrate absorption and desorption in crop and fallow rotation
Published 2021-01-01“…Additionally, Results indicated that application of 2, 4, 8 and 16 gram layered double hydroxides/kilogram soil led to 34%, 44%, 58% and 69% reduction in N-nitrate concentration of soil leachates, respectively, compared to control. …”
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6615
Attempt to save Friendship, or What the Liberator of Prague Did in Czechoslovakia in May 1968
Published 2020-09-01“…The article introduces the publication of the recently declassified archival documents of the Russian State Archive of Contemporary History (RGANI) and the Archive of Foreign Policy of the Russian Federation concerning the stay of a delegation of Soviet military leaders in the Czechoslovak Socialist Republic on May 8-14, 1968, led by Marshal of the Soviet Union I.S. Konev. In August 2018, at the initiative of the Prague 6 City Council, metal “information plates” were installed on the pedestal of the monument to Marshal Konev, where among other things it was stated that “In 1968, he personally backed the intelligence surveillance preceding the invasion of the armed forces of the Warsaw Pact into Czechoslovakia". …”
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6616
Long-term effects of maternal exposure to surgical stress at the earliest stage of pregnancy on blood pressure and behavior in offspring of OXYS rats
Published 2018-01-01“…Thus, OXYS dams’ exposure to surgical stress at their early pregnancy led to such effects in the offspring as elevated SAP and DAP, decreased overall activity and increased anxiety.…”
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6617
The heterogeneity of Pinus yunnanensis plantation growth was driven by soil microbial characteristics in different slope aspects
Published 2025-01-01“…The slope aspect caused the difference of soil microorganisms, further affected the soil characteristics and led to the heterogeneity of aboveground forest growth. …”
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6618
Nontyphi Salmonella Empyema with Bronchopleural Fistula in a Patient with Human Immunodeficiency Virus
Published 2018-01-01“…Empyema complicated by bronchopulmonary fistula likely led to failure of intrapleural fibrinolytic therapy and the patient ultimately required decortication in addition to antibiotics. …”
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6619
An automated adaptive trading system for enhanced performance of emerging market portfolios
Published 2025-02-01“…Emerging market (EM) investors have seen two major downturn events in the 2020s, namely the COVID-19 pandemic and the Russia-Ukraine conflict, both of which have strongly affected EM portfolios’ risk-return profiles and increased their correlations with their developed market counterparts, eliminating much or all of EMs’ diversification benefits. This has led to major capital outflows from EM countries, further destabilizing these fragile economies. …”
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6620
Practical Minimum Sample Size for Road Crash Time-Series Prediction Models
Published 2020-01-01“…Decreasing the sample sizes led to less prediction accuracy up to a sample size of 25; then, the accuracy increased for the 15-year sample size. …”
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