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  1. 6421

    Artisanal and farmer bread making practices differently shape fungal species community composition in French sourdoughs by Michel, Elisa, Masson, Estelle, Bubbendorf, Sandrine, Lapicque, Léocadie, Nidelet, Thibault, Segond, Diego, Guézenec, Stéphane, Marlin, Thérèse, Devillers, Hugo, Rué, Olivier, Onno, Bernard, Legrand, Judith, Sicard, Delphine

    Published 2023-01-01
    “…Although industrialization led to the selection and spread of specific fermenting microbial strains, there are still ongoing artisanal processes that may allow the conservation of a wider species diversity and genetic diversity. …”
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  2. 6422

    Trials and tribulations: a qualitative exploration of researcher perspectives on navigating the challenges of health system implementation research by Natalie Taylor, April Morrow, Julia Steinberg, Emily Hogden, Deborah Debono, Elijah Tyedmers, Priscilla Chan, Gabriella Tiernan

    Published 2025-01-01
    “…This qualitative study aimed to capture the experiences of a small research team coordinating a large, multisite implementation trial (the Hide and Seek Project) in the Australian healthcare setting.Design A qualitative approach was used, whereby members of the Hide and Seek Project research team were invited to take part in semistructured focus groups led by an external facilitator. The focus group guide was developed to explore the experiences of the research team (including challenges and lessons learnt) as they moved through key study activities. …”
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  3. 6423

    Plant Adaptation and Soil Shear Strength: Unraveling the Drought Legacy in <i>Amorpha fruticosa</i> by Hao Jiang, Xiaoqing Chen, Gang Xu, Jiangang Chen, Dongri Song, Ming Lv, Hanqing Guo, Jingyi Chen

    Published 2025-01-01
    “…Climate change has led to an increasing frequency of droughts, potentially undermining soil stability. …”
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  4. 6424

    Advancing the Taxonomy of the Diatom <i>Pseudo-nitzschia</i> Through an Integrative Study Conducted in the Central and Southeastern Adriatic Sea by Tina Bonačić, Jasna Arapov, Ivana Bušelić, Ivana Lepen Pleić, Blanka Milić Roje, Tina Tomašević, Mia Bužančić, Marija Mladinić, Silvia Casabianca, Antonella Penna, Sanda Skejić, Živana Ninčević Gladan

    Published 2025-01-01
    “…This integrative approach led to the identification of eight species: <i>Pseudo-nitzschia allochrona</i>, <i>Pseudo-nitzschia calliantha</i>, <i>Pseudo-nitzschia delicatissima</i>, <i>Pseudo-nitzschia fraudulenta</i>, <i>Pseudo-nitzschia mannii</i>, <i>Pseudo-nitzschia multistriata</i>, <i>Pseudo-nitzschia pseudodelicatissima</i>, and <i>Pseudo-nitzschia subfraudulenta</i>. …”
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  5. 6425

    Phosphogypsum as Fertilizer: Impacts on Soil Fertility, Barley Yield Components, and Heavy Metals Contents by M Barka Outbakat, Moussa Bouray, Redouane Choukr-Allah, Mohamed El Gharous, Kamal El Omari, Khalil El Mejahed

    Published 2024-12-01
    “…In fact, when compared to the control, the application of 1.5, 3, and 4.5 t/ha of PG led to a remarkable increase in grain yield by 21%, 34%, and 39%, respectively. …”
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  6. 6426

    Tree shrew as a new animal model for musculoskeletal disorders and aging by Xiaocui Wei, Honghao Li, Jingyang Qiu, Jianlin Jiao, Xiongtian Guo, Gaosheng Yin, Ping Yang, Yi Han, Qiongzhi Zhao, Hao Zeng, Zhi Rao, Xuefei Gao, Kai Li, Pinglin Lai, Sheng Zhang, Chengliang Yang, Di Lu, Xiaochun Bai

    Published 2025-01-01
    “…Surgery-induced IDD models were successfully established in tree shrews, in which the lumbar spine instability model developed slow progressive disc degeneration with more similarity to the clinical state, whereas the needle puncture model led to the rapid development of IDD with more severe symptoms. …”
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  7. 6427

    Families’ opinions about their involvement in care during hospitalization: a mixed-methods study by Josien M. Woldring, Wolter Paans, Reinold O. B. Gans, Hinke M. van der Werf, Marie Louise Luttik

    Published 2025-01-01
    “…Subsequent in-depth interviews led to the development of a model demonstrating that this involvement is sequentially related to the themes of acknowledgement, alignment, and collaboration. …”
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  8. 6428

    Bioprinted hydrogels in bone regeneration: a bibliometric analysis by Huijie Zhang, Xiaoyu Li, Zhenyu Jia, Kun Jiao, Kun Jiao, Chen Liu, Chen Liu, Zixiang Deng, Yushu Bai, Xianzhao Wei, Xiaoyi Zhou

    Published 2025-02-01
    “…A total of 811 institutions and 1,166 researchers from 41 countries/regions contributed to these publications. Among them, China led in terms of the number of articles published, single-country publications (SCP), and multi-country publications (MCP). …”
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  9. 6429

    Identifying the top research priorities in medically not yet explained symptoms (MNYES): a James Lind Alliance priority setting partnership by Mark Edwards, Danielle Varley, Natalie Smith, Petros Perros, Jonathan Gower, Arvind Kaul, Nicholas Gall, Andrew Stephen Moriarty, Christina Maria van der Feltz-Cornelis, Jennifer Sweetman, Jennifer Gilligan, Stephanie Hayle, James Sampford, Iman Elfeddali

    Published 2022-07-01
    “…Research into such symptoms in general has been poorly funded over the years and so far has been primarily researcher-led with minimal input from patients, caregivers and clinicians; and sometimes has been controversial.Design JLA PSP method. …”
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  10. 6430

    Reference Intervals (RIs) of the Bone Turnover Markers (BTMs) in Children and Adolescents: A Proposal for Effective Use by Vincenzo Brescia, Roberto Lovero, Antonietta Fontana, Roberta Zerlotin, Silvia Concetta Colucci, Maria Grano, Angela Pia Cazzolla, Francesca Di Serio, Vito Crincoli, Maria Felicia Faienza

    Published 2024-12-01
    “…The proof of concentrations with insignificant changes until puberty led to identification of two groups of RI relating to the covariables (age and sex) for each biomarker.…”
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  11. 6431

    ALDOA contributes to colorectal tumorigenesis and metastasis by targeting YAP by Liang Sun, Ting Lu, Linhua Jiang, Huihui Yao, Qixuan Xu, Jie Sun, Xiaoqin Yang, Songbing He, Xinguo Zhu

    Published 2025-01-01
    “…Mechanistically, high ALDOA expression inhibited AMP-activated protein kinase (AMPK) phosphorylation possibly through regulating cellular glycolysis or the formation of v-ATPase-regulator-AXIN/LKB1 complex, which led to Yes-associated protein (YAP) unphosphorylation and enhanced the proliferative and migratory potential of CRC cells. …”
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  12. 6432

    Comprehensive analysis of publications concerning combinations of immunotherapy and targeted therapies for hepatocellular carcinoma: a bibliometric study by Biling Gan, Lei Wu, Shunan Zhou, Zhihong Chen, Fan Wu, Lianqun Xu, Zhenrong Chen, Honghui Ma, Peijia He, Dan Fang, Ning Shi

    Published 2025-02-01
    “…Mainland China dominated the publication output, contributing 40% (N = 202), followed by significant contributions from the United States and Japan. Kindai University led institutional contributions, accounting for 7.9% of the total (N = 40). …”
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  13. 6433

    Human Strategy Learning-Based Multi-Agent Deep Reinforcement Learning for Online Team Sports Game by Seongbeen Lee, Gyuhyuk Lee, Wongyeom Kim, Junoh Kim, Jisun Park, Kyungeun Cho

    Published 2025-01-01
    “…However, limitations such as repetitive behavior patterns and challenges in maintaining systems during redesigns have led to increased research into reinforcement learning-based AI. …”
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  14. 6434

    The SERPINB4 gene mutation identified in twin patients with Crohn’s disease impaires the intestinal epithelial cell functions by Xiao-Mei Ouyang, Jun-Hui Lin, Ying Lin, Xian-Ling Zhao, Ya‐Ni Huo, Lai-Ying Liang, Yong-Dong Huang, Gui-Jing Xie, Peng Mi, Zhen-Yu Ye, Bayasi Guleng

    Published 2025-01-01
    “…The single-nucleotide difference in the SERPINB4 gene, which was unique to the twin patients with CD, led to the substitution of lysine by a glutamic acid residue. …”
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  15. 6435

    Near-Peer Coaching to Enhance Operative Learning: An Educational Innovation for Surgical Training by Alexander J. Papachristos, MSurgicalEd, Elizabeth Molloy, PhD, Juanita N. Chui, MD, Monica Ghidinelli, PhD, Simon Kitto, PhD, Debra Nestel, PhD, Benjamin P. T. Loveday, PhD

    Published 2024-09-01
    “…A prospective cohort study was conducted over a 6-month period following design and implementation of a trainee-led near-peer coaching model; “SPICE” (Set goals, Plan, Imagine, Comment and feedback, Evaluate and reflect). …”
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  16. 6436

    Association between COVID-19 severity and relatively high serum adiponectin levels at the time of admission by Ryohei Mineo, Shiro Fukuda, Shigehito Suzuki, Yoshito Ito, Sachiko Tamba, Takuya Sugiyama, Yuya Fujishima, Hitoshi Nishizawa, Iichiro Shimomura, Koji Yamamoto, Yuji Matsuzawa

    Published 2024-07-01
    “…At the beginning of 2020, coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) led to epidemics worldwide. Obesity and visceral fat accumulation have been reported to be independent risk factors for severe COVID-19. …”
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  17. 6437
  18. 6438

    Freedom of expression, aspiration and gender: A cultuling in the student demonstration by Siti Nurbayani, Elly Malihah, Millary Agung Widiawaty, Moh. Dede, Bayu Iqbal Anshari, Asep Mahpudz, Erry Sukriah, Sri Wahyuni

    Published 2025-01-01
    “…On April 11, 2022, during the COVID-19 pandemic, millennial and Gen-Z students led widespread protests in several Indonesian cities. …”
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  19. 6439

    Impact of antibiotic prophylaxis on gut microbiota in colorectal surgery: insights from an Eastern European stewardship study by Irina Cezara Văcărean-Trandafir, Roxana-Maria Amărandi, Iuliu Cristian Ivanov, Loredana Mihaiela Dragoș, Mihaela Mențel, Ştefan Iacob, Ştefan Iacob, Ana-Maria Muşină, Ana-Maria Muşină, Elena-Roxana Bărgăoanu, Cristian Ene Roată, Cristian Ene Roată, Ștefan Morărașu, Ștefan Morărașu, Valeri Țuțuianu, Marcel Ciobanu, Mihail-Gabriel Dimofte, Mihail-Gabriel Dimofte

    Published 2025-01-01
    “…We analyzed fecal samples collected from patients before and 7 days post-antibiotic treatment, focusing on the V3–V4 region of the 16S rRNA gene.ResultsOur findings indicate that inconsistent antibiotic prophylaxis policies—varying in type, dosage, or therapy duration—significantly impacted the gut microbiota and led to more frequent dysbiosis compared to stricter prophylactic antibiotic practices (single dose, single product, limited time).DiscussionWe emphasize the need for standardized antibiotic prophylaxis protocols to minimize dysbiosis and its associated risks, promoting more effective antimicrobial use, particularly in low- and middle-income countries (LMICs).…”
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  20. 6440

    Acromegaly: Is earlier diagnosis possible? Exploration of a screening algorithm to select high-risk patients by Tessa N.A. Slagboom, David de Jong, Peter H. Bisschop, Madeleine L. Drent

    Published 2025-03-01
    “…Conclusion: We found that our best algorithm led to the detection of more than half of patients with previously diagnosed acromegaly. …”
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