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6241
Vitamin D Toxicity Managed with Peritoneal Dialysis
Published 2021-01-01“…Workup for his hypercalcemia led to the diagnosis of vitamin D toxicity as shown by a level greater than 200 ng/dL (Ref: 20–50 ng/mL) was confirmed by liquid chromatography-mass spectroscopy. …”
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6242
Glucagon-like peptide-1 and glucose-dependent insulinotropic polypeptide agonists for the treatment of obesity and diabetes mellitus
Published 2024-04-01“…The availability of various GLP-1RAs offers flexibility in diabetes management, but the surge in their prescription has led to a global shortage. Health authorities are working to address this issue, while pharmaceutical companies are exploring new paths to improve the quality of these drugs. …”
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6243
SleepNow – A combined cognitive behavioral therapy for insomnia and physical exercise intervention in men with metastatic prostate cancer: results from a feasibility randomized con...
Published 2025-02-01“…SleepNow is a manualized 12-week program consisting of bi-weekly sessions of physical exercise and four nurse-led sessions of CBT-I. Patients in usual care received no insomnia treatment. …”
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6244
GOLPH3 inhibits glioma cell apoptosis through the JNK signaling pathway
Published 2025-01-01“…Furthermore, GOLPH3 knockdown led to the activation of the JNK signaling pathway, as indicated by elevated phosphorylation of JNK and c-Jun. …”
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6245
Identifying and Ranking Technological Capabilities to Enhance Resilience of the Supply Chain
Published 2021-11-01“…Also, the combined use of fuzzy Delphi methods to confirm the indicators and the SWARA method has led to the stability of the results.…”
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6246
INTRASPECIFIC VARIABILITY OF THE Sus1 SUCROSE SYNTHASE GENE IN Pisum sativum ACCESSIONS
Published 2018-03-01“…In coding sequences, 47 SNPs were found, wherein the most variable was the exon II. 16 exon SNPs led to amino acid substitutions. Six of them were deleterious and may potentially influence protein folding and stability. …”
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6247
Anti-angiogenic effects of cationic zinc (II) phthalocyanine derivatives through photodynamic therapy
Published 2025-01-01“…Both the ZnPcs demonstrated minimal cytotoxicity in the absence of light, confirming their safety as photosensitizers. ZnPc-PDT led to significant cell death via apoptosis. ZnPc1 exhibited enhanced ROS generation, particularly at elevated concentrations. …”
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6248
Association of CYP2C9∗3 and CYP2C8∗3 Non-Functional Alleles with Ibuprofen-Induced Upper Gastrointestinal Toxicity in a Saudi Patient
Published 2023-01-01“…This is the first reported Saudi patient homozygous for CYP2C9∗3 and CYP2C8∗3 variant alleles, which led to ibuprofen-induced upper GI toxicity. This case demonstrates the importance of contemplating CYP2C9 and CYP2C8 genetic variations when administrating NSAIDs like ibuprofen. …”
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6249
Structural Improvement of the ω-Type High-Speed Rail Clip Based on a Study of Its Failure Mechanism
Published 2019-01-01“…Finally, the clip was then structurally improved taking into account the stiffness and mass, which led to its resonant frequencies shifting away from the high-frequency excitation range, hence avoiding resonance failure of the subject clip.…”
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6250
CooccurrenceAffinity: An R package for computing a novel metric of affinity in co-occurrence data that corrects for pervasive errors in traditional indices.
Published 2025-01-01“…Analysis of co-occurrence data with traditional indices has led to many problems such as sensitivity of the indices to prevalence and the same value representing either a strong positive or strong negative association across different datasets. …”
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6251
Formulation Design of Orally Disintegrating Film Using Two Cellulose Derivatives as a Blend Polymer
Published 2025-01-01“…Our results, including DSC and FTIR results, led us to conclude that the HPMC/HPC blend films were micro-immiscible, but they were macro-miscible when the amount of the minor component was sufficiently small. …”
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6252
Predicting patients’ sentiments about medications using artificial intelligence techniques
Published 2024-12-01“…Abstract The increasing development of technology has led to the increase of digital data in various fields, such as medication-related texts. …”
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6253
The Effectiveness of Novel Growth Regulator and Fertilizer to Improve Quality and Yield of Spring Wheat
Published 2024-12-01“…The results showed GR3F2 need-based led to the highest plant height (69.8cm) and leaf area (7.63 cm2). …”
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6254
Effect of Sexual Skills Counseling With Cognitive-Behavioral Approach on Sexual Assertiveness in Women Suffering from Marital Disillusionment
Published 2024-11-01“…Conclusion: Sexual skills counseling with a cognitive-behavioral approach led to an increase in sexual assertiveness in women suffering from marital disillusionment. …”
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6255
Creating Intangible Value through a Corporate Employee Portal
Published 2017-01-01“…Increasing business competition and information technology development have both led to huge corporate organizational changes and have raised the importance of intangible assets along the value chain. …”
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6256
Local Self-Governments in Hungary: Recent Changes through Central European Lenses
Published 2019-11-01“…The study confirmed the initial hypothesis that the business management rules set out with insufficient prudence, deficiencies in the control system, and excessive borrowing in foreign exchange led to bankruptcy of a number of local self-governments and consequently jeopardised the proper provision of public services. …”
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6257
Impacts of Livestock Grazing on Wild Ungulate Habitat in the Khata Corridor, Bardiya, Nepal
Published 2023-01-01“…Lower availability of forage around the village led to the concerted effort of grazing in the forest, increasing the higher effective stocking density in winter, leading to the competition with wild ungulates. …”
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6258
Comparison of Goal Achievement during an Early, Intensive Nutrition Intervention Delivered to People with Upper Gastrointestinal Cancer by Telephone Compared with Mobile Applicatio...
Published 2024-01-01“…Telephone nutrition intervention delivery led to a higher frequency of goal achievement compared to the mobile app intervention. …”
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6259
GPR55 in the tumor microenvironment of pancreatic cancer controls tumorigenesis
Published 2025-01-01“…ResultsDeficiency of GPR55 in the TME led to reduced tumor weight and volume, and altered the immune cell composition of tumors, favoring an anti-tumorigenic environment by increasing the number of CD3+ T cells, particularly CD8+ T cells, and the expression of PDL1 on macrophages. …”
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6260
Perceptions of care and family support from patients and family caregivers during the COVID-19 pandemic: a phenomenological study in Spain
Published 2025-01-01“…Limited family support led to feelings of loneliness, isolation, and emotional distress among patients, exacerbating their vulnerability. …”
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