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5901
Intracranial germ cell tumors: advancement in genomic diagnostics and the need for novel therapeutics
Published 2025-01-01“…Development of targeted therapeutics against KIT has led to the prospect of targeted therapy in germinoma. …”
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5902
Complete Genome Sequence Analysis of the First Imported Mpox Virus Clade Ib Variant in China
Published 2025-01-01“…The rapid evolution of MPXV, coupled with increased international interactions, has led to a gradual rise in mpox cases in certain regions of Asia, mostly involving MPXV clade II and its branch strains. …”
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5903
Technological Properties of Model System Beef Emulsions with Encapsulated Pumpkin Seed Oil and Shell Powder
Published 2020-03-01“…The use of shell powder as a phosphate replacer led to significantly higher pH values and thus to significantly higher residual nitrite level: 70.87–74.64 mg/kg (C treatments) vs . 56.79–62.16 mg/kg (F treatments). …”
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5904
Effect of phosphoric rock on the chemical, microbiological and enzymatic quality of poultry, equine and cattle manure compost mix
Published 2022-09-01“…First, the addition of phosphate rock led to an increase in total and available P and a decrease in water-soluble phosphorus and inhibitory effects of phosphatase activity. …”
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5905
A facile synthesis by spark plasma sintering of mobile lithium ions into oxynitride glass-ceramic matrix: Insight and perspective
Published 2025-01-01“…The quest for efficient energy storage solutions has led to the development of solid-state Li-on batteries (SSBs), which utilize solid-state electrolyte (SSE) materials instead of organic liquid electrolytes. …”
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5906
Studying flame-retardancy, smoke and toxicity of fiber-reinforced composites manufactured via modified resins and metallic coatings
Published 2025-03-01“…The addition of 9,10-dihydro-9-oxo-10-phosphaphenanthrene-10-oxide (DOPO) and Cu film surface coating led to superior smoke suppression with negligible smoke production (maximum Ds of 0–4, VOF4 of 1 at 180–240 s), whereas unmodified composites showed significant smoke development (maximum Ds of 759 at 240 s, VOF4 of 1157). …”
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5907
β-Glucan induced plasma B cells differentiation to enhance antitumor immune responses by Dectin-1
Published 2025-01-01“…In mouse models of Lewis lung cancer (LLC) tumors, combining β-glucan with programmed death-1(PD-1) blocking antibodies led to increase recruitment of CD19+ B cells in the tumor microenvironment (TME), higher numbers of germinal centers B cells (GC B) in the spleen and draining lymph node (DLN), elevate Ig production, and delay tumor progression. …”
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5908
Filtration Performance of Layering Masks and Face Coverings and the Reusability of Cotton Masks after Repeated Washing and Drying
Published 2021-08-01“…Scanning electron microscopy revealed that washing and drying led to the gradual deconstruction of cotton fibers at the scale of several micrometers to hundreds of nanometers in the form of delamination of the fiber wall and fibrillation of the nanofiber constituents. …”
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5909
Relationship between Calcium-binding Ability and Structure of Soybean Protein Based on the Change of Preparation
Published 2025-01-01“…Heat treatment and enzymatic hydrolysis unfolded the secondary structure, leading to the enhancement of hydrophobicity and the exposure of the calcium-binding sites. Enzymolysis led to the aggregation of small molecular weight proteins, causing a spatial restructuring of the protein. …”
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5910
Investigating the role of endocytosis in the uptake of photoassimilates in Gracilariopsis lemaneiformis (Rhodophyta)
Published 2025-02-01“…Inhibition of endocytic activity led to an initial decline in photosynthetic efficiency of algal thalli within a few hours, which was followed by an increase as inhibition duration extended, yet the growth rate of the thalli remained substantially suppressed. …”
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5911
Exploring the Potential Effectiveness of <i>Croton tiglium</i> Oil and Its Nano-Emulsion on <i>Earias insulana</i> (Lepidoptera: Nolidae)
Published 2025-01-01“…</i> (Lepidoptera: Nolidae) is a major pest of cotton and other crops in Egypt, and the widespread use of insecticides has led to resistance. This study evaluates, for the first time, the bioactivity of <i>Croton tiglium</i> (Malpighiales: Euphorbiaceae) oil and its nano-emulsion (CTNE) against 25 newly hatched larvae of <i>E. insulana</i> Boisd. …”
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5912
Cautionary note: Chatbots generate fictitious references on the topics related to oral pathology
Published 2024-03-01“…Conversely, BARD exhibited a substantial 88 % inaccuracy rate in total references, with only 4 references managing to provide the correct title. Notably, the DOI led to the accurate manuscript in only 12 % (9) of references generated by ChatGPT and 4 % (8) of references from BARD. …”
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5913
A short ncRNA modulates gene expression and affects stress response and parasite differentiation in Leishmania braziliensis
Published 2025-02-01“…Studies of the mechanisms regulating gene expression in Leishmania led us to investigate noncoding RNAs (ncRNAs) as regulatory elements. …”
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5914
PREDICTING THE LEARNING PATH TO LEARNER’S OPTIMUM COMPREHENSION
Published 2024-04-01“…The quest to achieve this singular purpose has led to the introduction of several learning techniques in the conventional learning environment, such as asking questions and conducting test after class, just to mention a few. …”
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5915
Evolution and importance of Molecular Microbiology in the Laboratory of the Provincial Center for Hygiene, Epidemiology and Microbiology
Published 2024-05-01“…Introduction: the need to have rapid, sensitive and specific laboratory techniques for the detection of pathogens that are difficult to diagnose led to the creation of the Molecular Biology Laboratory at the Provincial Center of Hygiene, Epidemiology and Microbiology of Villa Clara. …”
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5916
High-Performance Liquid Chromatography Assay for Moxifloxacin in Brain Tissue and Plasma: Validation in a Pharmacokinetic Study in a Murine Model of Cerebral Listeriosis
Published 2012-01-01“…The relative standard deviation of intra- and inter-day assays was <10%. This validated method led to a short retention time (8.0 min) for moxifloxacin. …”
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5917
Understanding the Impacts of Recurrent Peat Fires in Padang Island – Riau Province, Indonesia
Published 2018-01-01“…We found that the global demands for agricultural commodities have led to massive peat drainage for monoculture farming on peat lands. …”
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5918
Balancing CIK Cell Cancer Immunotherapy and PPAR Ligands: One Potential Therapeutic Application for CNS Malignancies
Published 2024-12-01“…Results Using a clinical applicable PPAR‐γ inhibitor, we showed that (1) PPARγ‐antagonist GW‐9662 suppressed tumor cell growth in both neuroblastoma and glioblastoma cells, (2) PPARγ inhibition had restricted effect on the expression of Wnt/β‐catenin associated genes, (3) inhibition of PPARγ led to downregulation of DNMT1 expression, supporting their hypothesized interaction in cancer, (4) a partial modulation of global LINE‐1 methylation levels was observed, indicating their role in epigenetic processes, and (5) Combining PPARγ inhibition with CIK cell immunotherapy enhanced cell lysis significantly. …”
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5919
APPLICATION OF INDONESIAN NURSING DIAGNOSIS STANDARDS IN NURSING DIAGNOSIS DOCUMENTATION IN CHILDREN WITH DENGUE HEMORRHAGIC FEVER
Published 2024-10-01“…Dengue Hemorrhagic Fever cases in Indonesia have experienced a shortening cycle, which has led to a rise in the incidence rate (IR) and a fall in the case facility rate (CFR). …”
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5920
Evaluation for Retinal Therapy for RPE65 Variation Assessed in hiPSC Retinal Pigment Epithelial Cells
Published 2021-01-01“…Results from this study led to reclassification of the synonymous variant to a pathogenic variant, providing the affected patients with access to RPE65 gene replacement therapy.…”
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