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5881
Expression and prognostic significance of the m6A RNA methylation regulator HNRNPC in HNSCC
Published 2025-02-01“…BackgroundN6-methyladenosine (m6A) RNA modification is crucial for tumor development and progression; however, which m6A regulators play a pivotal role in head and neck squamous cell carcinoma (HNSCC) remains ambiguous.MethodsUtilizing the Cancer Genome Atlas (TCGA) database, the expression levels of m6A regulators in HNSCC were examined, which led to the identification of heterogeneous nuclear ribonucleoprotein C (HNRNPC) as a key gene. …”
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5882
The burden of group A Streptococcus (GAS) infections: The challenge continues in the twenty-first century
Published 2025-01-01“…However, post-COVID-19, the situation has led to a steep increase in GAS infection rates in Europe, the United States, Australia, and New Zealand, which triggers a global concern. …”
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5883
Comparison of “Rose, Aeroleaf, and Tulip” vertical axis wind turbines (VAWTs) and their characteristics for alternative electricity generation in urban and rural areas
Published 2025-03-01“…Global warming and reliance on fossil fuel resources have led to heightened interest in advancing renewable energy resources. …”
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5884
Estimation of Radon Flux Density Changes in Temporal Vicinity of the Shipunskoe Earthquake with <i>M</i><sub>w</sub> = 7.0, 17 August 2024 with the Use of the Hereditary Mathematic...
Published 2025-01-01“…As a result of the modeling, it is shown that the strong seismic impact and subsequent processes led to changes in the radon flux in the accumulation chamber. …”
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5885
Gaia-4b and 5b: Radial Velocity Confirmation of Gaia Astrometric Orbital Solutions Reveal a Massive Planet and a Brown Dwarf Orbiting Low-mass Stars
Published 2025-01-01“…Here we present RV follow-up observations of 28 M and K stars with candidate astrometric substellar companions, which led to the confirmation of two systems, Gaia-4b and Gaia-5b, identification of five systems that are single lined but require additional data to confirm as substellar companions, and the refutation of 21 systems as stellar binaries. …”
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5886
Optimizing Lightweight Recurrent Networks for Solar Forecasting in TinyML: Modified Metaheuristics and Legal Implications
Published 2024-12-01“…The limited nature of fossil resources and their unsustainable characteristics have led to increased interest in renewable sources. …”
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5887
Single-mode microwave heating for food science research: Understanding specific microwave effects and reliability concerns
Published 2025-09-01“…Simulations and measurements disclosed notable temperature gradients within the heating system, which were also affected by the solvent volume and type. Abnormal convection led to increased temperatures in the upper solution layers, and this abnormal convection-induced higher temperature could affect the experimental outcomes in scientific research. …”
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5888
A Scoping Review of Educational and Training Interventions on Parkinson’s Disease for Staff in Care Home Settings
Published 2025-01-01“…Educational interventions led to significant improvements in staff knowledge, confidence, and care practices. …”
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5889
46,XY Disorder of Sex Development Caused by 17α-Hydroxylase/17,20-Lyase Deficiency due to Homozygous Mutation of CYP17A1 Gene: Consequences of Late Diagnosis
Published 2018-01-01“…Hydrocortisone and ethinyl-estradiol supplementation therapy led to incomplete withdrawal of antihypertensive drug and breast development progression to Tanner stage B2 and slight height increase, respectively. …”
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5890
Extreme Environment Streptomyces: Potential Sources for New Antibacterial and Anticancer Drug Leads?
Published 2019-01-01“…It is because of technical advances in isolation, fermentation, spectroscopy, and genomic studies which led to the efficient recovering of Streptomyces and their new chemical compounds with distinct activities. …”
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5891
Formability Assessment Based on Q-Value for Optimizing the Deep Drawing Process of Automotive Parts Made from Aluminum Alloys Sheet
Published 2025-01-01“…Furthermore, increasing the male drawbead height effectively reduced wrinkling but led to increased thinning, whereas increasing the contra-bead radius had the opposite effect.…”
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5892
SAHA inhibits lung fibroblast activation by increasing p66Shc expression epigenetically
Published 2024-12-01“…Additionally, mito‐SOX assay confirmed that SAHA treatment led to a marked accumulation of mitochondrial reactive oxygen species (ROS). …”
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5893
Impact of Wave COVID-19 Responses on Black Carbon Air Pollution in Moscow Megacity Background
Published 2024-02-01“…Decrease of traffic and industrial enterprise emissions during lockdown led to the change of BC daily and weekly trends. …”
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5894
Functional Metaplasticity of Hippocampal Schaffer Collateral-CA1 Synapses Is Reversed in Chronically Epileptic Rats
Published 2017-01-01“…Hence, studying the cellular and molecular cascades involved in the key mechanism of information storage in the brain, synaptic plasticity, has led to enormous knowledge in this field. A major open question applies to the interdependence between synaptic plasticity and its behavioral correlates. …”
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5895
From Polydeoxyribonucleotides (PDRNs) to Polynucleotides (PNs): Bridging the Gap Between Scientific Definitions, Molecular Insights, and Clinical Applications of Multifunctional Bi...
Published 2025-01-01“…Importantly, despite their widespread use in cosmetology and aesthetic dermatology, the interchangeable use of the terms “PDRN” and “PN” in the scientific literature (to describe polymers of varying lengths) has led to considerable confusion within the medical and scientific communities. …”
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5896
Codon optimized influenza H1 HA sequence but not CTLA-4 targeting of HA antigen to enhance the efficacy of DNA vaccines in an animal model
Published 2024-12-01“…The study findings revealed that the codon-optimized HA gene (pcHA) led to increased protein synthesis, as evidenced by elevated mRNA levels. …”
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5897
Nano silica and meso silica extracted from rice husk waste utilized for enhancing leather properties
Published 2025-01-01“…Therefore, this study focused on the extraction of the nanoparticles from rice husk waste for using in leather finishing which can be the sustainable materials that not only enhance the quality and performance of leather but also led to the waste minimization. The highly active, polar, porous, and huge interior area of biogenic silica nanoparticles and mesoparticles make them an excellent substitute for manufactured silica. …”
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5898
The History of the Brazilian Sardine (<i>Sardinella brasiliensis</i>) Between Two Fishery Collapses: An Ecosystem Modeling Approach to Study Its Life Cycle
Published 2024-12-01“…Furthermore, the higher fishing mortality may have led the stock to collapse.…”
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5899
Enhancing RF Fingerprint Generation in Power Amplifiers: Unequally Spaced Multitone Design Approaches and Considerations
Published 2024-01-01“…The rapid growth of Internet of Things (IoT) devices and communication standards has led to an increasing demand for data security, particularly with limited hardware resources. …”
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5900
TRENCH FEVER AS WAR INFECTION
Published 2024-10-01“…The adaptation of the pathogen to spread by body lice has led to changes in the clinical and epidemiological characteristics of the disease. …”
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