Amorphous silica reduces N2O emissions from arable land at the field plot scale by Mathias Hoffmann, Oscar Rodrigo Monzon Diaz, Isabel Zentgraf, Wael Al-Hamwi, Maren Dubbert, Mathias Stein, Maire Holz, Jörg Schaller, Jörg Schaller

“…If future studies confirm the effect of ASi on N2O emissions, the soil ASi depletion by agricultural practice in the last decades may have led to a substantial increase of N2O emissions.…”
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Pre-injection of exosomes can significantly suppress ovarian cancer growth by activating the immune system in mice by Yuanyuan Wang, Changyi Zhang, Huimin Zeng, Liangliang Wang, Zanhong Wang, Zhiqiang Han

“…Therefore, we discovered whether combining PD-L1 blockade led to further tumor regression. However, although the combination group showed complete tumor regression, this difference did not reach statistical significance. …”
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A non-conditioned bone marrow transplantation mouse model to study clonal hematopoiesis and myeloid malignancies by Sofia Bentivegna, Marwa Almosailleakh, Lin-Pierre Zhao, Mikkel Bruhn Schuster, Sébastien Benquet, Alexander Balhuizen, Helga Fibiger Munch-Petersen, Lene Dissing Sjö, Mads Hald Andersen, Nicolas Dulphy, Bo Porse, Kirsten Grønbæk

“…The transplantation of Tet2 −/− BM cells led to a progressive expansion of the donor cells in W41 recipients. …”
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Manipulating Intracellular Oxidative Conditions to Enhance Porphyrin Production in <i>Escherichia coli</i> by Bahareh Arab, Murray Moo-Young, Yilan Liu, C. Perry Chou

“…Notably, overexpression of <i>sodA</i> alone led to a 72.9% increase in total porphyrin production (1.56 g/L) while improving the UP-III/UP-I ratio to 1.94. …”
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BMP6, a potential biomarker of inflammatory fibrosis and promising protective factor for dilated cardiomyopathy by Feng Jiang, Jiayang Tang, Xiaoqi Wei, Hai Pan, Xinyi Fan, Peng Zhang, Shuzhen Guo

“…Notably, BMP6 knockdown led to a decrease in SMAD6 expression and a marked elevation in COL1A1 expression levels, indicating its antifibrotic role. …”
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Mutations in Homocysteine Metabolism Genes Increase Keratin N-Homocysteinylation and Damage in Mice by Kamila Borowczyk, Jacek Wróblewski, Joanna Suliburska, Noriyuki Akahoshi, Isao Ishii, Hieronim Jakubowski

“…The accumulation of N-Hcy in hair keratin led to a progressive reduction of N-Hcy-keratin solubility in sodium dodecyl sulfate, from 0.39 ± 0.04 in wild-type mice to 0.19 ± 0.03, 0.14 ± 0.01, and 0.07 ± 0.03 in Mthfr−/−, Cse−/−, or Cbs−/−animals, respectively. …”
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Predicting Traffic Accident Risk in Seoul Metropolitan City: A Dataset Construction Approach by Ji-Woong Yang, Hyeon-Jin Jung, Tae-Wook Kim, Han-Jin Lee, Ellen J. Hong

“…In contemporary society, the rapid progression of urbanization and technological advancements has led to a substantial increase in the number of vehicles, consequently elevating the rate of traffic accidents. …”
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Evaluation of Antifungal Analysis of Selected Food Products Obtained In the Local Markets of Peshawar KPK Pakistan by Shakir Ullah, Hayat Khan, Yasir Zubair, Muneeba Zubair, Usman Saeed, Maryam Bibi, Eidul Ahad, Zeeshan Ullah, Adam khan Gohar, Usman Shah, Sadiq Ur Rahman, Muhammad Iqbal Khan Rahman

“…Among the positive food samples, Fusarium spp was more predominant 28(43%) led by Aspergillus spp 25( 38.5%). In comparison, Mucor and Cladosporium were found in low frequency with percentages of 7(10.8%), 5(7.7%). …”
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Post-burns persistent inflammation leads to kidney PANoptosis with Caspases pathway activation by Guang Yang, Minghui Wang, Mulan Qahar, Jinqing He, Zhiwei Lai, Sanmu Li, Dehua He, Xuefei Yan, Zuying Xiong, Zibo Xiong, Thu H. Le

“…Furthermore, polarized M1 macrophages led to increased MPC5 podocyte death. Following dexamethasone intervention, kidney function and injuries were alleviated in CKD mice. …”
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Interneuron FGF13 regulates seizure susceptibility via a sodium channel-independent mechanism by Susan Lin, Aravind R Gade, Hong-Gang Wang, James E Niemeyer, Allison Galante, Isabella DiStefano, Patrick Towers, Jorge Nunez, Maiko Matsui, Theodore H Schwartz, Anjali Rajadhyaksha, Geoffrey S Pitt

“…Interneuron-targeted deletion of Fgf13 led to perinatal mortality associated with extensive seizures and impaired the hippocampal inhibitory/excitatory balance while excitatory neuron-targeted deletion of Fgf13 caused no detectable seizures and no survival deficits. …”
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CCL5 Induces a Sarcopenic-like Phenotype via the CCR5 Receptor by Francisco Aguirre, Franco Tacchi, Mayalen Valero-Breton, Josué Orozco-Aguilar, Sabrina Conejeros-Lillo, Josefa Bonicioli, Renata Iturriaga-Jofré, Daniel Cabrera, Jorge A. Soto, Mauricio Castro-Sepúlveda, Marianny Portal-Rodríguez, Álvaro A. Elorza, Andrea Matamoros, Felipe Simon, Claudio Cabello-Verrugio

“…The results showed that TA overexpression of CCL5 led to sarcopenia by reducing muscle strength and mass, muscle-fiber diameter, and sarcomeric protein content, and by upregulating E3-ligases. …”
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Exploring the optimal reconstruction strategy for Enneking III defects in pelvis bone tumors: a finite element analysis by Jiazhuang Zhu, Jianping Hu, Kunpeng Zhu, Xiaolong Ma, Zhen Huang, Chunlin Zhang

“…Results Compared with Scheme A, reconstruction of the Enneking III region (Schemes B and C) led to a more uniform stress distribution and lower peak stress in the pelvis. …”
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FcRn-enhancing mutations lead to increased and prolonged levels of the HIV CCR5-blocking monoclonal antibody leronlimab in the fetuses and newborns of pregnant rhesus macaques by Joanna Zikos, Gabriela M. Webb, Helen L. Wu, Jason S. Reed, Jennifer Watanabe, Jodie L. Usachenko, Ala M. Shaqra, Celia A. Schiffer, Koen K. A. Van Rompay, Jonah B. Sacha, Diogo M. Magnani

“…Further, a single dose of leronlimab-PLS led to complete CCR5 receptor occupancy in mothers and newborns for almost a month after birth. …”
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Impacts of different pig slurry application methods on soil quality indicators in a maize-soybean cropping sequence in the Sub-humid Pampas of Argentina by Vanesa Pegoraro, Cristian Cazorla, Omar Bachmeier, Tomás Baigorria, Mónica Boccolini, Jimena Ortiz, Claudio Lorenzon, Susana Hang, Marta Zubillaga

“…In maize, IS and AS were more efficient in retaining N within the soil-plant system, whereas, in soybean, the SS led to higher yields.…”
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Protective effects of resveratrol and naringenin against nonylphenol-induced oxidative stress in rats by Haitham S. Elewa, Dawlat A. Salama, Mohamed S. Hikal, Mohamed F. Abd El hamid, Mohamed H. Eid, Fatma M. A. Khalil, Muayad S. Albadrani, Khaled Abdelaal, Ahmed I. El-Tokhy

“…Moreover, significant escalation was observed in the levels of Malondialdehyde. Also, NP treatment led to a significant decrease in serum total testosterone and testis weight, accompanied with concurrent elevation in estradiol level compared to NC and DMSO groups. …”
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Enhancement of Single‐Molecule Magnet Properties by Manipulating Intramolecular Dipolar Interactions by Jia‐Qi Huang, Qi‐Wei Chen, You‐Song Ding, Xiao‐Fei Zhu, Bing‐Wu Wang, Feng Pan, Zhiping Zheng

“…This structural transformation has led to significantly enhanced intramolecular dipolar interactions and a reduced transverse component of the crystal fields, increasing the energy barrier from 150(8) K for Er2Cl2 to 264(4) K for Er2Cl3 and extending its magnetic relaxation time at 2 K by 2500 times with respect to Er2Cl2. …”
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Interaction Between Malat1 and miR-499-5p Regulates Meis1 Expression and Function with a Net Impact on Cell Proliferation by Salma A. Fahim, Manon Ragheb, Ibrahim Hassan Fayed, Aya Osama, Ahmed Karam, Sameh Magdeldin, Rana Metwale, Mohamed Dief Allah Abdalmoneam Elsayed, Ahmed Abdellatif, Hesham A. Sadek, Shereen Ahmed El Sobky, Nada El-Ekiaby, Injie Omar Fawzy, Ahmed Ihab Abdelaziz

“…For the first time, we demonstrated that the overexpression of miR-499-5p led to the downregulation of Meis1 mRNA and protein in C166 cells by directly binding to its 3’UTR. …”
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Analysis of Forest Cover in the Tumba-Lediima Nature Reserve (RTL-DRC) by Sylvestre Frey, André Musas A Musas, Nestor Anzola Kibamba, Sebastien Kidushi Mboma, Tege Simboni Simboni, Djonive Munene Asidi

“…The main drivers of deforestation identified are agricultural expansion, illegal exploitation of forest resources and urbanization. These activities have led to the fragmentation of critical habitats, putting endemic and threatened species at risk, while also compromising the ecological integrity of the reserve. …”
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Brighter children? The association between seasonality of birth and child IQ in a population-based birth cohort by Vincent W V Jaddoe, Régine P M Steegers-Theunissen, Henning Tiemeier, Albert Hofman, Frank C Verhulst, Nina H Grootendorst-van Mil

“…Adjustment for different covariates led to a substantial reduction (−65.0% change, in a seasonal trend analysis) of this association. …”
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Microstructure and Mechanical Properties of High-Entropy Alloy FeCoNiCr(X) Produced by Laser Directed Energy Deposition Process: Effect of Compositional Changes by Ekaterina Kovalenko, Igor Krasanov, Ekaterina Valdaytseva, Stanislav Stankevich, Olga Klimova-Korsmik, Marina Gushchina

“…Replacing the element Mn with Cu in HEA FeCoNiCrMn led to a shift in the dendrite growth from one to two predominant directions and a decrease in the average microhardness by 20%.…”
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