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5841
Characterization of selenium nanoparticles extracted from Bacillus subtilis and its antibacterial effects in Onychostoma macrolepis: Insight into ferroptosis
Published 2025-01-01“…To further explore the mechanism of SeNPs against bacterial infection, we examined the changes before and after bacterial infection, and the results showed that large amounts of peroxide were produced under A. hydrophila infection in O. macrolepis fry, and then the excessive accumulation of peroxides led to a large amount of ferroptosis in the liver. …”
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5842
High-throughput tracking enables systematic phenotyping and drug repurposing in C. elegans disease models
Published 2025-01-01“…The observed phenotypes were diverse, but mutations of genes predicted to have related functions led to similar behavioural differences in worms. …”
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5843
Fatigue State Evaluation of Urban Railway Transit Drivers Using Psychological, Biological, and Physical Response Signals
Published 2025-01-01“…The results show that fatigue reduced the participants’ reaction time and cognitive ability and led professional drivers to make more conservative decisions. …”
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5844
Composite solid sand reinforcement grouting material preparation and diffusion characteristics of slurry-water replacement grouting
Published 2025-07-01“…Utilizing the Box-Behnken design within the response surface methodology, the physical and chemical properties of the raw materials were thoroughly investigated. This approach led to an optimal mix ratio: 33.2 % coal gangue, a water-cement ratio of 0.756 for Material A, and an equal mass ratio of Materials A and B. …”
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5845
Assessment of Compliance with Mandatory Government Policy on Environmental Sanitation in a Nigerian Urban Area
Published 2024-12-01“…Widespread pollution and poor public health conditions in many areas of Nigeria led to an authoritarian military regime's introduction of mandatory monthly sanitation day. …”
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5846
Knowledge mapping and emerging trends in cognitive impairment associated with chronic pain: A 2000–2024 bibliometric study
Published 2025-01-01“…Publication numbers showed a steady increase, peaking in 2022. The United States led in contributions, with Harvard Medical School emerging as the most prominent institution involved. …”
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5847
Genomic characterization and evolutionary analysis of a Getah virus variant from piglets in central China
Published 2025-02-01“…Furthermore, several amino acid substitutions in E2 protein were identified among different GETV groups and the substitution at D262th N site led to an additional glycosylation modification. …”
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5848
Albino lethal 13, a chloroplast‐imported protein required for chloroplast development in rice
Published 2024-06-01“…Our study's findings reveal that RNAi‐mediated knockdown of OsAL13 led to a pronounced albino phenotype, reduced chlorophyll and carotenoid contents, a vesicle chloroplast structure, and a decrease in the expression of chloroplast‐associated genes. …”
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5849
A distinct metabolomic pattern revealed intestinal microenvironment factor-mediated food allergy in a BALB/c mouse model
Published 2024-11-01“…In response to GA, T-cell balance was disrupted, with aberrant production of interleukin (IL)-4, interferon (IFN)-γ, IL-10, and IL-2 in the spleen. GA led to a disrupted intestinal microenvironment homeostasis, including increased pH and water content, impaired intestinal antioxidant capacity and epithelial barrier function, decreased short-chain fatty acid production, and microbial dysbiosis, which was strongly correlated with GA severity. …”
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5850
Evaluation of Endoscopic Ultrasound Image Quality Is Necessary in Endosonographic Assessment of Early Gastric Cancer Invasion Depth
Published 2012-01-01“…Low-quality EUS images led to an incorrect diagnosis of invasion depth of EGC, independent of tumor location or size.…”
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5851
Identification and Characterization of the <i>ROP GTPase</i> Gene Family in Strawberry and the Positive Role of <i>FveROP4</i> in Fruit Resistance to Gray Mold
Published 2024-12-01“…Subsequent analysis revealed that overexpression of <i>FveROP4</i> and <i>FveCAROP4</i> genes led to increased accumulation of reactive oxygen species. …”
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5852
Desferrioxamine Reduces Oxidative Stress in the Lung Contusion
Published 2013-01-01“…In the control+DFX and contusion+DFX groups, 100 mg/kg DFX was given intraperitoneally once a day just after the contusion and the day after the contusion. Contusions led to a meaningful rise in the malondialdehyde (MDA) level in lung tissue. …”
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5853
Antioxidative and functional properties of plum oil cake protein isolate prepared by different drying methods
Published 2024-01-01“…The freeze-drying method led to a much higher antioxidant activity of PPIF. …”
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5854
Inducing cylindrical and spherical defocus after implantation with new generation intraocular lenses improves intermediate and near visual acuity
Published 2024-12-01“…In both IOL groups, induced cylinder and sphere independently led to significant improvement in near and distance vision (p < 0.05). …”
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5855
How Much Time Should Be Waited and What Are the Main Findings to Evaluate the Hepatocellular Carcinoma Response to Regorafenib? A Real-Life Experience
Published 2021-01-01“…The reasons why regorafenib was maintained are explained based on clinical and imaging findings, showing how this decision led to an excellent response. Conclusions. The knowledge of the main adverse events described in the pilot clinical trials can avoid unnecessary withdrawal of regorafenib. …”
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5856
Exploring the Potential of Selenium-Containing Amine (Se-AMA) to Enhance Photosynthesis and Leaf Water Content: New Avenues for Carbonic Anhydrase Modulation in <i>Arabidopsis thal...
Published 2025-01-01“…Global changes and growing demands have led to the development of new molecular approaches to improve crop physiological performances. …”
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5857
Grazing reduces shrub-facilitated diversity of ground-dwelling arthropods in semiarid ecosystems
Published 2025-01-01“…The decreased arthropod species turnover between microhabitats in grazed plots relative to ungrazed plots led to alterations of their original community assembly. …”
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5858
Soil Quality and Water Redistribution Influences on Plant Production over Low Hillslopes on Reclaimed Mined Land
Published 2018-01-01“…Coal surface mining in northern Great Plains USA led to reclamation experiments with soil respreading. …”
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5859
Phenomenological understanding of the contribution of bulk and grain boundary precipitates on strengthening in prolonged-aged Al-Zn-Mg-Cu aluminium alloys
Published 2025-03-01“…Meanwhile, the aspect ratio of grain boundary S-phase precipitates that sporadically developed from the interconnected clusters present along the grain boundaries was progressively increased with ageing time, contributing to improved mechanical stability of grain boundary precipitates. Prolonged ageing led to a small decrease in tensile strength from 567 MPa to 526 MPa and minor increase in elongation from ∼11 % to ∼13 %. …”
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5860
SILAC-based quantification reveals modulation of the immunopeptidome in BRAF and MEK inhibitor sensitive and resistant melanoma cells
Published 2025-01-01“…Moreover, we identified putative tumor-specific cryptic HLA peptides linked to these processes that might represent exploitable targets for cancer immunotherapy.ConclusionsWe have developed a new mass spectrometric approach that allowed us to investigate the effects of common MAPK inhibitors on the immunopeptidome of melanoma cells. This finally led to the discovery of new potential targets for cancer immunotherapy.…”
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