Advancing the Fight Against Cervical Cancer: The Promise of Therapeutic HPV Vaccines by Qian Zheng, Misi He, Zejia Mao, Yue Huang, Xiuying Li, Ling Long, Mingfang Guo, Dongling Zou

“…While prophylactic vaccination programs have led to substantial reductions in both HPV infection rates and cervical cancer incidence, considerable burdens of HPV-related diseases persist, particularly in developing countries with inadequate vaccine coverage and uptake. …”
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Immunological Dynamics Associated with Direct-Acting Antiviral Therapies in Naive and Experimented HCV Chronic-Infected Patients by Grenda Leite Pereira, Andréa Monteiro Tarragô, Walter Luiz Lima Neves, Pedro Vieira da Silva Neto, Priscila Sarmento de Souza, Juliana dos Santos Affonso, Keyla Santos de Sousa, Jéssica Albuquerque da Silva, Allyson Guimarães Costa, Flamir da Silva Victoria, Marilu Barbieri Victoria, Adriana Malheiro

“…However, the immunological dynamics of patients infected with HCV is poorly understood. This fact led us to investigate the immune system of naive and experienced patients, who we followed before the therapy and three months after the end of treatment. …”
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Effectiveness of acupuncture for equine laminitis: Systematic review and meta-analysis by Faisal Fikri, Agus Purnomo, Salipudin Tasil Maslamama, Muhammad Thohawi Elziyad Purnama

“…These investigations have led to the implementation of dry needling, hemo-acupuncture, aqua-acupuncture, and electroacupuncture as alternate treatments for equine laminitis.…”
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Anaesthetic Management of a Neonate with Ebstein’s Anomaly Undergoing a Meningomyelocele Surgery: A Case Report by Prakriti, Monika Yadav, Vaishali Gupta, Komal Yadav, Shikha Garg

“…On examination, an enlarged head and swelling on the lumbar spine led to an ultrasound that confirmed hydrocephalus and meningocele. …”
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Mixture of Bacillus Amyloliquefaciens and Bacillus Pumilus Modulates Community Structures of Rice Rhizosphere Soil to Suppress Rice Seedling Blight by Jiang Nan, Qiu Jiehua, Tian Dagang, Shi Huanbin, Liu Zhiquan, Wen Hui, Xie Shuwei, Chen Huizhe, Wu Meng, Kou Yanjun

“…Furthermore, this mixture led to higher stochastic assembly (average |βNTI| < 2) and reduced selection pressures on rice rhizosphere bacteria compared with individual strain applications. …”
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Rethink of Individual Transferable Quota Fishery Management System in China: A Case Study in Zhejiang Province, China by Yuan Jiang, Zoe Qu, Huijuan Hao, Siying Wang

“…This study finds out that on the surface, the reason for the failure is the inaction of local governments, which has led to inadequate definition, transfer, supervision, and protection of fishing rights. …”
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Evolution of the Radiation Shielding, Optical, and Luminescence Properties of PbO₂-SiO₂ Glass Systems and the Influence of Rare Earth Elements (Eu, Ce, Yb) by Mioara Zagrai, Ramona-Crina Suciu, Radu Cristian Gavrea, Vasile Rednic

“…Samples PS0–PS3 revealed semiconducting behavior and may be considered a promising host matrix for solar cells and w-LED applications.…”
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Psychiatric assessment in image-based sexual abuse case: a case report on imputability in personality disorder with narcissistic traits by Lorenzo Lodde, Claudia Zandara, Andrea Martella, Mirko Manchia, Mirko Manchia, Pasquale Paribello, Irene Mascia, Martina Pinna

“…We report on a case of a 27-year-old young adult who is accused of image-based sexual abuse and other crimes, for whom the examining judge requested psychiatric assessment.MethodsWe conducted anamnestic collection (family, physiological and pathological, psychiatric, and toxicological), direct evaluation of the examinee, assessment of acquired health records, psychodiagnostic tests (i.e. graphic tests: Machover test, Koch test), Montreal Cognitive Assessment, Minnesota Multiphasic Personality Inventory 2, Pathological Narcissism Inventory, State-Trait Anger Expression Inventory 2, Toronto Alexithymia Scale, Thematic Apperception Test.ResultsThe clinical forensic assessment led to a diagnosis of Unspecified Personality Disorder (predominantly narcissistic traits) according to the DSM-5 criteria. …”
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Effect of yoga exercises on lung volumes, vital capacity, and attention span in school going students by Reema Joshi, Manisha Rathi, Komal Preet Kaur

“…Conclusions Yoga exercises led to improvement in lung volumes, vital capacity, and attention in school-going students.…”
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Assessment of different enrichment methods revealed the optimal approach to identify bovine circRnas by Yixin Wang, Jian Wang, Robert J. Gruninger, Tim A. McAllister, Mingzhou Li, Le Luo Guan

“…RNA-sequencing analysis revealed that different approaches led to varied ratio of uniquely mapped reads, false-positive rate of identifying circRNAs, and the number of circRNAs per million clean reads (Padj <0.05). …”
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An Effect of Ursodeoxycholic Acid on Inflammation, Steatosis and Liver Fibrosis and Atherogenesis Factors in Patients with Non-Alcoholic Fatty Liver Disease: Results of the USPEH S... by M. V. Mayevskaya, M. Yu. Nadinskaia, V. D. Lunkov, I. Yu. Pirogova, E. V. Chesnokov, Kh. B. Kodzoeva, V. T. Ivashkin

“…The use of UDCA in patients with NAFLD led to a decrease in ALT (p &lt; 0.001), AST (p &lt; 0.001) and GGT (p &lt; 0.001) activity; total cholesterol concentration (p &lt; 0.001); triglycerides (p &lt; 0.001); and LDL (p &lt; 0.001) in the blood and the FLI liver steatosis index (p &lt; 0.001). …”
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Effect of equilibrium relative humidity on explosion characteristics parameters of humid magnesium dust by Xinyu Xiong, Kai Gao, Changquan Ji, Jie Mu, Bin Li, Dan Zhang, Yadong Xu, Lifeng Xie

“…However, in the case of a high degree of “oxygen-poor” state, the derived hydrogen instead became burdensome, resulting in an excessive amount of magnesium dust that was unavailable for reaction. This led to a decrease in the explosion characteristics parameters of humid magnesium dust, with the maximum decreases in Pmax and (dp/dt)max being 45.8 kPa and 2.1 kPa/ms respectively.…”
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PD-1 suppresses human CD38+ circulating Tfr cells and regulates humoral immunity by Heng Zhang, Hui Zheng, Lin Guo, Ying Tong, Xiaolu Ma, Yanchun Wang, Renquan Lu, Cuncun Chen, Suhong Xie

“…Flow or beads sorted cells were cultured ex vivo for proliferation and functional analysis.Results Anti-PD-1 therapy significantly increased the levels of IgG and IgA in the periphery of HCC patients. Anti-PD-1 treatment led to an increase in plasmablasts and a notable rise in circulating T follicular regulatory (cTfr) cells, while changes in circulating B cells, T follicular helper cells, or regulatory T cells were not significant. …”
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THE NORTHERN TERRITORIES OF WESTERN SIBERIA: DEMOGRAPHIC TRENDS AND GROWTH PARADOXES by Andrei G. Shelomentsev, Vladimir M. Kurikov, Kseniya S. Goncharova, Alina V. Istratii

“…The active phase of resource exploitation led to substantial population growth and rapid urbanization in the Khanty-Mansiysk and Yamalo-Nenets Autonomous Okrugs, resulting in the establishment of over 20 new cities. …”

Leptin Regulates Proliferation and Apoptosis in Human Prostate by Eduardo Leze, Jorge Luiz Alves-Pereira, Sicilia Colli, Fernanda Silveira Cavalcante, Francisco José Sampaio, Cristiane da Fonte Ramos

“…Results. The leptin treatment led to an increase cellular proliferation (C=21.8±0.5; L=64.8±0.9; P<0.0001) and in the expression of Bax (C=0.4±0.1; L=0.9±0.2; P<0.05) while Bcl-2 (C=19.9±5.6; L=5.6±1.8; P<0.05), Bcl-x (C=0.2±0.06; L=0.07±0.02; P<0.05), and aromatase expressions (C=1.9±0.6; L=0.4±0.1; P<0.04) were significantly reduced. …”
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Impact of Different Sugar Syrups on the Development of the Fat Body in Worker Bees (<i>Apis mellifera macedonica</i>) by Svilen B. Lazarov, Petya M. Veleva, Atanas Z. Atanasov, Ivaylo S. Hristakov, Zlatko Puškadija

“…Apiinvert and honey/water syrup promoted higher fat body stages, while Isosweet led to elevated fifth degrees of development but raised concerns about potential toxicity due to the hydroxymethylfurfural (HMF) formation of improperly stored syrups. …”
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Redefining NSP12 activity in SARS-CoV-2 and its regulation by NSP8 and NSP7 by Deepa Singh, Tushar Kushwaha, Rajkumar Kulandaisamy, Vikas Kumar, Kamal Baswal, Saras H. Tiwari, Arkadyuti Ghorai, Manoj Kumar, Saroj Kumar, Soumya De, Aparoy Polamarasetty, Deepak Sehgal, Madhumohan R. Katika, Suresh Gadde, Marceline Côté, Sarala R. Kayampeta, Mohan Babu Appaiahgari, Krishna K. Inampudi

“…The presence of only one cofactor, either NSP7 or NSP8, completely inhibited NSP12 activity and led to RNA template detachment. Computational analyses of different NSP12 complexes suggested that binding of NSP7 or NSP8 alone to NSP12 constricts the RNA entry channel, which was higher in the presence of NSP8, making it inappropriate for RNA entry/binding. …”
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The impact of short-term changes in sleeping and eating patterns on glucometabolic health and gut microbiota in healthy young adults: a proof-of-concept controlled feeding study by Jiehua Chen, Ruijie Zhang, Chao Zhou, Louise Weiwei Lu, Dana Feng, Haiqiao Zou, Ran Gao, Xinying Zhang, Peiyi Chen, Jiayue Zhu, Haoxie Xu, Nina Zeng, Cijuan Zhang, Bin Liu, Mingfu Wang, Qian Ge, Caiqun Ouyang, Feng Chen

“…Circadian rhythm misalignment led to significantly higher levels of fasting glucose and homeostatic model assessment for insulin resistance (HOMA-IR) of subjects compared to baseline and failed to recover to the baseline level in circadian rhythm realignments. …”
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Vitamin C, Phenolic Compounds and Antioxidant Capacity of Broccoli Florets Grown under Different Nitrogen Treatments Combined with Selenium by Peñas Elena, Zielińska Danuta, Gulewicz Piotr, Zieliński Henryk, Frias Juana

“…There were no evidences of the influence of N treatment on vitamin C content whilst Se (IV or VI) uptake led to a significant reduction of this vitamin in broccoli florets, irrespective of the N source. …”
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Clinical efficacy of Methylene Blue mediated antimicrobial Photodynamic Therapy (PDT) using 680 nm Diode Laser in patients undergoing Open Flap Debridement: An Original Research by Soundarya Singh, Manisha Rout, Mayur Kaushik, Shilpa Sharma, Aprajita Srivastava

“…The possibility of the development of resistance to antibiotics by the target organism has led to the development of a new antimicrobial concept with fewer complications. …”
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