Practical solutions for overcoming artificial disulfide scrambling in the non-reduced peptide mapping characterization of monoclonal antibodies by Andrew Kleinberg, Yuan Mao, Ning Li

“…Common misconceptions (e.g. avoiding basic-pH digestion to prevent disulfide scrambling) have led to the development of alternative reagents and conditions that can alleviate this issue, but yield problematic digestion profiles. …”
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Novel transcripts of EMT driving the malignant transformation of oral submucous fibrosis by Smitha Sammith Shetty, Kanaka Sai Ram Padam, Mohit Sharma, Adarsh Kudva, Pratik Patel, Raghu Radhakrishnan

“…Integration of bioinformatics and proteomics led to the discovery of the EMT genes MMP9, SPARC, and ITGA5 as novel candidates. …”
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Les dynamiques agropastorales pendant le Haut-Empire sur les Hautes-Chaumes des Monts du Forez (Puy-de-Dôme, Loire, France). Architecture saisonnière, occupation du sol et gestion... by Antoine Scholtès, Jacqueline Argant, Hervé Cubizolle, Jacques Verrier, Priscille Chapuis

“…The same objectives have led geoarchaeological research in the Mont du Forez. …”
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Increased but not pristine soil organic carbon stocks in restored ecosystems by Irene Ascenzi, Jelle P. Hilbers, Marieke M. van Katwijk, Mark A. J. Huijbregts, Steef V. Hanssen

“…We find that restoration projects have, since their inception, led to significant SOC increases compared to the degraded state in 12 out of 16 ecosystem-previous land-use combinations, with mean SOC increases thus far that range from 25% (grasslands; 10–39%, 95% CI) to 79% (shrublands; 38–120% CI). …”
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Study on Deformation Law of Subway Construction under Passing Existing Line in Short Distance by Cong-Shuang Luo, Yi-Hong Cheng, Zhe Bai, Tong Shen, Xu-Yang Wu, Qing-Guo Wang

“…With the large-scale development and utilization of underground space projects, the subway-led Rail Transit Project is developing vigorously, and the safety and stability of subway under passing existing projects have become a key issue for the future. …”
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Placenta Percreta Invading Broad Ligament and Parametrium in a Woman with Two Previous Cesarean Sections: A Case Report by Mansoureh Vahdat, Abolfazl Mehdizadeh, Elaheh Sariri, Shahla Chaichian, Zahra Najmi, Maryam Kadivar

“…We presented a case of placenta percreta invading left broad ligament and parametrium in a woman with two previous cesarean sections, which led to massive intraoperative hemorrhage during hysterectomy and transient ischemic encephalopathy. …”
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A bibliometric and visualized analysis of heartland virus by Huiying Zhang, Huiying Zhang, Leiliang Zhang, Leiliang Zhang

“…VOSviewer, CiteSpace, Scimago Graphica, and Bibliometrix were used to process the data and visualize the results.ResultsA stable trend in publication numbers was observed, with 82 articles from 17 countries. The United States led in publications, with significant contributions from the Centers for Disease Control and Prevention-USA. …”
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Repair effects of offcut-carbon-fiber-powder-modified PU-PMMA copolymer on flexure-after-impact behaviors of composite laminate by Shang-Nan Tsai, Hsin-Ting Chiang

“…Tensile and flexural tests showed that 1 wt% oCFP improved tensile strength from 38 MPa to 43.31 MPa and flexural strength from 56.02 MPa to 82.21 MPa, while further addition of oCFP led to reductions in these strengths. Although oCFP-modified PU-PMMA did not significantly restore the impacted laminates' flexural strength, the repairing effect was still more pronounced than that of a commercial epoxy adhesive, demonstrating potential as a repair or structural adhesive.…”
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An Experimental and Computational Study on the Effects of Ball Milling on the Physicochemical Properties and Digestibility of a Canna Starch/Tea Polyphenol Complex by Yizhou Wang, Kejun Di, Ying Sun, Xiaojing Li, Jiong Zheng, Fusheng Zhang

“…Infrared results revealed that ball milling led to a non-covalent interaction between the tea polyphenols and starch. …”
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Essure Microinsert Abdominal Migration after Hysteroscopic Tubal Sterilization of an Appropriately Placed Essure Device: Dual Case Reports and Review of the Literature by Shadi Rezai, Meghan LaBine, Hunter Azdel Gomez Roberts, Isamarie Lora Alcantara, Cassandra E. Henderson, Malvina Elmadjian, Dilfuza Nuritdinova

“…However, there have been reports of device migration that have led to failed tubal occlusion as well as several other serious complications resulting from the presence of the device in the abdominal cavity. …”
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Recent Developments on Novel 2D Materials for Emerging Neuromorphic Computing Devices by Muhammad Hamza Pervez, Ehsan Elahi, Muhammad Asghar Khan, Muhammad Nasim, Muhammad Asim, Arslan Rehmat, Malik Abdul Rehman, Mohammed A. Assiri, Shania Rehman, Jonghwa Eom, Muhammad Farooq Khan

“…The rapid advancement of artificial intelligent and information technology has led to a critical need for extremely low power consumption and excellent efficiency. …”
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Identification of Genes Regulating Gene Targeting by a High-Throughput Screening Approach by Fabien Delacôte, Christophe Perez, Valérie Guyot, Catherine Mikonio, Pierrick Potrel, Jean-Pierre Cabaniols, Christophe Delenda, Frédéric Pâques, Philippe Duchateau

“…We showed that siRNAs directed against the ATF7IP gene, encoding a protein involved in chromatin remodeling, stimulated HGT by a factor of three to eight, at various loci and in different cell types. This method thus led to the identification of a number of genes, the manipulation of which might increase rates of targeted recombination.…”
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The Case for Musical Instrument Training in Cerebral Palsy for Neurorehabilitation by Ana Alves-Pinto, Varvara Turova, Tobias Blumenstein, Renée Lampe

“…These multiple demands during instrument playing, together with the entertaining character of music, have led to the development and investigation of music-supported therapies, especially for rehabilitation with motor disorders resulting from brain damage. …”
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Analysing Informal Governance Arrangements in Small-Scale Fisheries: A Case Study of Norton, Zimbabwe by Tawanda Jimu, Samantha Williams, Manfred Spocter

“…As a result, the weak hierarchical arrangements coupled with the economic challenges have led to the emergence of informal fishing, which is dominant and visible in Norton SSF and contributes to local fishing livelihoods. …”
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A Pink Herring in the Colon: A Case Report of Eosinophilic Colitis Masking Invasive Adenocarcinoma of the Colon by David Malcolm Milne, Jason Rattan, Alyssa Muddeen, Amrit A. Rambhajan

“…We present a case of a patient whose biopsy at colonoscopy revealed eosinophilic colitis which led to a delay in the diagnosis and subsequent treatment of colon cancer. …”
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Pernicious Effects of Toe Sucking Habit in Children by Deepika Pai, Saurabh Kumar, Abhay T. Kamath, Vipin Bhaskar

“…Appropriate interception of habit and timely orthodontic intervention led to not only early interception of cross-bite but also decrease in pyrexial episodes. …”
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Leveraging Partial Labels for Cervical Lesion Classification via a Multilabel Approach by Margaret Dy Manalo, Kota Aoki, Shuqiong Wu, Mariko Shindo, Yutaka Ueda, Yasushi Yagi

“…These findings suggest that the improved attention mechanisms led to enhanced localization of lesions, enabling focus on the fine details of each lesion. …”
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Ultrasound, Echocardiography, MRI, and Genetic Analysis of a Fetus with Congenital Diaphragmatic Hernia and Partial 11q Trisomy by Yolanda Fernández-Perea, Lutgardo García-Díaz, Javier Sánchez, Guillermo Antiñolo, Salud Borrego

“…The current and constant progress in ultrasound techniques has led to the improvement of the prenatal diagnosis of this malformation. …”
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Mechanism of podophyllotoxin-induced ovarian toxicity via the AMPK/TSC1/mTOR/ULK1 axis in rats on the basis of toxicological evidence chain (TEC) concept by Jingjing Li, Yanzhao Zhang, Mingyue Wei, Junjie He, Huifeng Ma, Zilong Chen, Jiajia Duan, Chuanxin Liu

“…Background: Podophyllotoxin is a compound with clinical effects, such as anticancer and antiacromegaly effects, but its systemic toxicity has led to extremely limited clinical application. Methods: Using the toxicological evidence chain (TEC) as a research method, our team constructed, for the first time, a rat model in which podophyllotoxin caused ovarian damage and investigated the mechanism of the toxic effects of podophyllotoxin on the ovaries. …”
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Case Report of Presumed (In)voluntary Capsaicin Intoxication Mimicking an Acute Abdomen by Simona Koprdova, Christine Schürmann, Dirk Peetz, Thomas Dürbye, Frank Kolligs, Herbert Koop

“…After 2½ hours, the patient developed severe abdominal pain, which led to hospital admission. In contrast to the severe symptoms, clinical, laboratory, and imaging examinations (ultrasound and plain X-ray of the abdomen) did not reveal any significant abnormalities. …”
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