Radiomics signature for dynamic monitoring of tumor inflamed microenvironment and immunotherapy response prediction by Enriqueta Felip, Paolo Nuciforo, Elena Garralda, Joan Frigola, Ramon Amat, Garazi Serna, Francesco Grussu, Kinga Bernatowicz, Olivia Prior, Marta Ligero, Christina Zatse, Rodrigo Toledo, Manel Escobar, Raquel Perez-Lopez

“…Cox models using aggregated CT-TIME scores from baseline images revealed a statistically significant reduction in the risk of PFS in the pan-cancer cohort (HR 0.62, 95% CI 0.44 to 0.88, p=0.007), and Kaplan-Meier analysis further confirmed substantial differences in PFS between patients with inflamed and uninflamed status (log-rank test p=0.009).Conclusions The signature holds promise for impacting clinical decision-making, pan-cancer patient stratification, and treatment outcomes in immune checkpoint therapies.…”
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Distribution of Airway Findings in ANCA-Associated Vasculitis: A 20-Year Observational Analysis by Megan M. Sullivan, Maximiliano Diaz Menindez, Hassan Baig, Anushka Irani, Ronald Butendieck, Benjamin Wang, Florentina Berianu, Carolyn Mead-Harvey, Andy Abril, Vikas Majithia

“…The primary outcome was time to relapse of the tracheobronchial inflammation after starting immunosuppressive medication, analyzed using the Kaplan–Meier method and log-rank tests. Secondary outcomes included severity of pulmonary disease on pulmonary function tests, endoscopic interventions, tracheostomy, or mortality during follow-up. …”
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Association of glucose to lymphocyte ratio with the risk of death in patients with atherosclerotic cardiovascular disease by Jinglin Lei, Wentao Duan, Xiaoxi Yao, Zheng Hu, Huihui Fan, Yifan Liu, Wenjian Zhong, Haipeng Li

“…Restricted cubic spline (RCS) curves were used to display the relationship between GLR and all-cause mortality visually, and two-segment Cox proportional hazards models were constructed on either side of the inflection points. Kaplan-Meier survival curves were further used to assess the relationship between GLR and mortality, and further subgroup analyses were performed. …”
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The association between metabolomic profiles of lifestyle and the latent phase of incident chronic kidney disease in the UK Population by Tingting Jin, Yunqi Wu, Siyi Zhang, Ya Peng, Yao Lin, Saijun Zhou, Hongyan Liu, Pei Yu

“…Finally, we performed Kaplan–Meier survival curve analysis on the significant variables identified in the AFT model. …”
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Association between insulin resistance indices and outcomes in patients with heart failure with preserved ejection fraction by Weicheng Ni, Ruihao Jiang, Di Xu, Jianhan Zhu, Jing Chen, Yuanzhen Lin, Hao Zhou

“…The mean age of the patients was 70.59 ± 10.6 years, with 5045 (58.04%) being male. The Kaplan-Meier survival analysis revealed that higher degree of the four IR indexes was associated with higher risk of MACE (all log-rank P < 0.05). …”
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Prognostic utility of neutrophil gelatinase-associated lipocalin (NGAL) levels for cardiovascular events in patients with stable coronary artery disease treated with percutaneous c... by Ting-Yu Lin, Hsin-Bang Leu, Yen-Wen Wu, Wei-Kung Tseng, Tsung-Hsien Lin, Hung-I Yeh, Kuan-Cheng Chang, Ji-Hung Wang, Wei-Hsian Yin, Chau-Chung Wu, Chun-Yao Huang, Shing-Jong Lin, Chien-Yi Hsu, Jaw-Wen Chen

“…Results During the mean follow-up period of 4.6 ± 1.7 years, 441 patients reached the primary endpoints. Kaplan-Meier analysis showed that event-free survival was significantly different between the first and third tertile groups (log-rank test, p < 0.001) in subjects categorized by NGAL levels. …”
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Modern perspective of the Rice Diet for hypertension and other metabolic diseases by Anthony Kuo, Pao-Hwa Lin, Yi-Ju Li, Friedrich C Luft, David López, Romeo Sommerfeld, Paul Ermler, Jana Fehr, Benjamin Bergner, Scott Sanoff, Francis Neelon, William McDowell, Smilla Fox, Abdullatif Ghajar, Elena Gensch, Cedric Lorenz, Martin Preiss, Tom Richter, Philip Klemmer, Anastacia Bohannon, Christoph Lippert

“…Further, we performed Kaplan-Meier survival analysis to compare 5-year survival probability of participants defined by baseline level of SBP.Results The database encompasses a wide array of health markers, including BP, weight, urine chloride (UCl) concentration and retinal features that offer a unique resource for studying the impact of the RDP on hypertension, diabetes and obesity. …”
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Deep Neck Infections: The Effectiveness of Therapeutic Management and Bacteriological Profile by Geanina Bandol, Mihail Dan Cobzeanu, Mihaela Moscalu, Octavian Dragos Palade, Liliana Moisii, Florentina Severin, Emilia Patrascanu, Florin Mocanu, Andrei Ionut Roman, Bogdan Mihail Cobzeanu

“…Comparative analysis of the Kaplan–Meier survival curves based on the presence of infection revealed a significantly lower survival in cases with a positive culture. …”
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Eficacia del nimotuzumab según índices inflamatorios en pacientes con cáncer de pulmón no microcítico avanzado by Kirenia Camacho Sosa, Mayra Ramos Suzarte, Carmen Elena Viada González, Elia Nenínger Vinageras, Eduardo Rafael Santiesteban Álvarez, Maurenis Hernández Pérez, Yoanna Ivette Flores Vega, Saylin Alfonso Alemán, Ramón Alberto Ortiz Carrodeguas, Soraida Candida Acosta Brooks, Pedro Pablo Guerra Chaviano, Ivis Mendoza Hernández, Tania Crombet Ramos, Agustín Lage Dávila

“…Se aplicó la estadística descriptiva, se utilizó el software x-tile 3.6.1 para el test de Kaplan Meier; se consideraron diferencias significativas cuando p< 0,05. …”
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Effect of Hyperthermic Intraperitoneal Perfusion Chemotherapy Combined with Radical Surgery and Capecitabine on Stage III Gallbladder Cancer by Sulai Liu, Zhendong Zhong, Weimin Yi, Zhangtao Yu, Zhihua Zhang, Guoyi Xia, Bo Jiang, Yinghui Song, Chuang Peng

“…Survival analysis was performed using the Kaplan–Meier method and parallel log-rank test. Results. …”
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立体定向放疗与全脑放疗局限性脑转移瘤的疗效预后分析

“…: 【目的】 探讨立体定向放射治疗(SRT)与全脑放射治疗(WBRT)在局限性脑转移瘤治疗中的疗效和预后,为合理应用SRT和WBRT提供依据65377;【方法】 选择2000年1月 ～ 2005年12月收治的转移灶≤4个且最大径≤4 cm脑转移患者60例,按照原发肿瘤类型(肺癌和非肺癌)65380;脑转移灶数目(单发和2 ～ 4个)65380;有无颅外转移和化疗与否四项因素进行匹配设计分为WBRT加SRT65380;单纯SRT和单纯WBRT治疗组,三组的治疗剂量分别为WBRT 30 ～ 36 Gy + SRT 18 ～ 20 Gy65380;SRT 28 ～ 32 Gy和WBRT 30 ～ 40 Gy,分析全组以及据原发肿瘤类型65380;脑转移灶数目65380;有无颅外转移亚组不同治疗方法在局部控制率65380;局部新病灶发生率(χ2检验)和生存率(Kaplan*9鄄Meier法和Log*9鄄rank检验)的差异65377;【结果】 全组局部控制率与局部新病灶发生率分别为80.0%(48/60)和20.0%(12/60)65377;全组患者中位生存时间13个月(3 ～ 36月),第165380;2年生存率分别是38.1%和14.3%65377;WBRT加SRT65380;单纯SRT和单纯WBRT治疗组的局部控制率分别为95.0%65380;80.0%和60.0%(P < 0.05),而局部新病灶发生率则分别为15.0%65380;35.0%和10.0%(P < 0.05)65377;WBRT加SRT65380;单纯SRT和单纯WBRT治疗组的中位生存期分别为865380;9和6个月,生存分析未显示不同治疗方法影响生存预后(P > 0.05),分层分析亦未显示不同治疗方法在不同原发肿瘤亚组中影响生存预后(P > 0.05),然而在单发脑转移患者和无颅外转移患者中,WBRT加SRT和单纯SRT治疗组的生存预后优于单纯WBRT治疗组,中位生存期分别为2365380;16和5个月(P < 0.05),以及1265380;9和5个月(P < 0.05)65377;【结论】 SRT可明显改善局限性脑转移瘤患者的局部控制率,但未行WBRT治疗的患者局部新发脑转移率明显增加65377;在预后较好的单发脑转移瘤患者和无颅外转移患者中,联合应用SRT和WBRT能显著提高生存率65377;…”
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Neutrophil to Lymphocyte Ratio Predicts Adverse Cardiovascular Outcome in Peritoneal Dialysis Patients Younger than 60 Years Old by Yingsi Zeng, Zijun Chen, Qinkai Chen, Xiaojiang Zhan, Haibo Long, Fenfen Peng, Fengping Zhang, Xiaoran Feng, Qian Zhou, Lingling Liu, Xuan Peng, Evergreen Tree Nephrology Association, Guanhua Guo, Yujing Zhang, Zebin Wang, Yueqiang Wen, Jiao Li, Jianbo Liang

“…NLR was categorized in triplicates: NLR≤2.74, 2.74<NLR≤3.96, and NLR>3.96. Kaplan-Meier cumulative incidence curve and multivariable COX regression analysis were used to determine the relationship between NLR and the incidence of adverse CV outcome, while a competitive risk model was applied to assess the effects of other outcomes on adverse CV prognosis. …”
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Oral Cyclophosphamide for Patients With Metastatic Castration-Resistant Prostate Cancer in a Scenario of Limited Health Care Resources by Diana del Cisne Pineda, Gabriel Berlingieri Polho, Yumi Ricucci Shinkado, Gustavo Alves Contado, Nathalia de Souza Crusoe, Vivian Naomi Horita, Joao Carlos Resende, Jamile Almeida Silva, Guilherme Fialho de Freitas, David Queiroz Muniz, Caio V. Suartz, Leopoldo Alves Ribeiro-Filho, Paulo M. Hoff, José Mauricio Mota

“…Survival estimates used the Kaplan-Meier method, and correlations were made with Chi-square test for categorical variables.RESULTSFrom January 2011 to January 2023, 341 patients with mCRPC received oral cyclophosphamide at a tertiary cancer center in São Paulo, Brazil. …”
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Incidence of constrained condylar and hinged knee implants and mid- to long-term survivorship: a register-based study from the Nordic Arthroplasty Register Association (NARA) by Jake von Hintze, Ville Ponkilainen, Annette W-Dahl, Nils P Hailer, Ove Furnes, Anne M Fenstad, Mona Badawy, Alma B Pedersen, Martin Lindberg-Larsen, Mika J Niemeläinen, Keijo Mäkelä, Antti Eskelinen

“…Methods: From 2000 to 2017, 5,134 CCK and 2,515 RHK primary TKAs were identified from the NARA database. Kaplan–Meier (K–M) survival and flexible parametric survival model (FPSM) analyses were performed to estimate revision risk, expressed as hazard ratio (HR) with 95% confidence intervals (CI), with minimally stabilized (MS) TKA acting as the control group (n = 456,137). …”
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Insulin resistance surrogates are associated with all-cause mortality and cardiovascular mortality in population with metabolic syndrome: a retrospective cohort study of NHANES by Jinhao Liao, Linjie Wang, Lian Duan, Fengying Gong, Huijuan Zhu, Hui Pan, Hongbo Yang

“…The multivariate Cox proportional hazards regression model, Kaplan-Meier survival curve, and log-rank tests were applied to determine the association between the five indices and all-cause mortality and cardiovascular mortality in the MetS population. …”
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Predicting patient outcomes with gene-expression biomarkers from colorectal cancer organoids and cell lines by Alexandra Razumovskaya, Mariia Silkina, Mariia Silkina, Mariia Silkina, Andrey Poloznikov, Timur Kulagin, Maria Raigorodskaya, Nina Gorban, Anna Kudryavtseva, Maria Fedorova, Boris Alekseev, Alexander Tonevitsky, Alexander Tonevitsky, Alexander Tonevitsky, Sergey Nikulin, Sergey Nikulin, Sergey Nikulin

“…Prognostic performance was evaluated through Kaplan-Meier survival analysis and log-rank tests, while independent prognostic significance was assessed using multivariate Cox proportional hazards modeling.ResultsA small set of genes showed consistent correlation with resistance to chemotherapy across different datasets. …”
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Single-cell RNA sequencing and AlphaFold 3 insights into cytokine signaling and its role in uveal melanoma by Hongyan Sun, Cunzi Li, Zuhui Pu, Zuhui Pu, Ying Lu, Ying Lu, Zijing Wu, Zijing Wu, Lan Zhou, Lan Zhou, Hongzhan Lin, Yumo Wang, Tao Zi, Lisha Mou, Lisha Mou, Ming-ming Yang

“…The UVM-specific gene signature demonstrated high predictive accuracy in ROC curve analysis and was associated with overall survival in Kaplan–Meier survival analyses. Additionally, AlphaFold 3 predicted the 3D structures of key proteins with high confidence. …”
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Association between red blood cell distribution width-to-albumin ratio and prognosis in post-cardiac arrest patients: data from the MIMIC-IV database by Yinhe Cai, Yinhe Cai, Yao Zhang, Yao Zhang, Ningzhi Zhou, Ningzhi Zhou, Yong Tang, Yong Tang, Haixia Zheng, Haixia Zheng, Hong Liu, Hong Liu, Jiahua Liang, Ruixiang Zeng, Shengqing Song, Yu Xia, Yu Xia

“…Restricted cubic spline, Kaplan–Meier (K-M) survival curves, and Cox proportional hazards regression model were used to explicate the relationship between the RAR index and all-cause mortality risk. …”
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The Effect of Systemic Inflammation and Clinicopathologic Features on Survival in Malignant Pleural Mesothelioma: A Multicenter Analysis by Nadiye Sever, Sedat Yıldırım, Ali Fuat Gurbuz, Delyadil Karakaş Kılıç, Esra Zeynelgil, Yunus Emre Altintaş, Berivan Deniz Çimik, Yeşim Ağyol, Ali Kaan Güren, Pınar Erel, Erkam Kocaaslan, Burak Paçacı, Mustafa Alperen Tunç, Abdussamet Çelebi, Nazım Can Demircan, Selver Işık, Rukiye Arıkan, Murat Araz, Serdar Karakaya, Murat Sarı, Osman Köstek, İbrahim Vedat Bayoğlu

“…Survival outcomes were analyzed using Kaplan–Meier methods, and prognostic factors were evaluated using Cox regression analysis. …”
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Machine learning cluster analysis identifies increased 12-month mortality risk in transcatheter aortic valve replacement recipients by Thomas Meredith, Thomas Meredith, Thomas Meredith, Farhan Mohammed, Amy Pomeroy, Sebastiano Barbieri, Sebastiano Barbieri, Erik Meijering, Louisa Jorm, David Roy, Jason Kovacic, Jason Kovacic, Jason Kovacic, Jason Kovacic, Michael Feneley, Michael Feneley, Michael Feneley, Christopher Hayward, Christopher Hayward, Christopher Hayward, David Muller, David Muller, David Muller, Mayooran Namasivayam, Mayooran Namasivayam, Mayooran Namasivayam

“…Survival analyses were performed with Kaplan–Meier and Cox proportional hazards models. …”
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