双链ＲＮＡ依赖的蛋白激酶在非小细胞肺癌预后预测及靶向治疗中的作用

“…【方法】 免疫组化检测２１２例ＮＳＣＬＣ中ＰＫＲ、ＩＧＦ-１Ｒ表达情况，并用于Ｋａｐｌａｎ-Ｍｅｉｅｒ生存分析。Ｗｅｓｔｅｒｎ Ｂｌｏｔｔｉｎｇ检测１３种肺癌细胞株ＰＫＲ、ｐ-ＰＫＲ表达；磺基罗丹明Ｂ法（ＳＲＢ）检测ＰＰＰ、Ｒａｐａｍｙｃｉｎ等药物作用后对高表达及低表达ｐ-ＰＫＲ细胞的抑制率。…”
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A prognostic signature of Glutathione metabolism-associated long non-coding RNAs for lung adenocarcinoma with immune microenvironment insights by Junxi Hu, Junxi Hu, Shuyu Tian, Shuyu Tian, Qingwen Liu, Qingwen Liu, Jiaqi Hou, Jiaqi Hou, Jun wu, Jun wu, Xiaolin Wang, Xiaolin Wang, Yusheng Shu, Yusheng Shu

“…A prognostic model was built with Cox and Least Absolute Shrinkage and Selection Operator (LASSO) methods and validated by Kaplan-Meier analysis, Receiver Operating Characteristic (ROC) curves, and Principal Component Analysis (PCA). …”
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Time to dietary diversity of complementary feeding improvements and its associated factors among infants aged 6–12 months in Ethiopia: evidence from performance monitoring for acti... by Feyisa Shasho Bayisa, Teshome Demis Nimani, Samuel Demissie Darcho, Abainash Tekola

“…The data management and analysis were performed using Stata version 17. The Kaplan–Meier survival curve (KM) and the log-rank test method were implemented. …”
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The Association Between the CALLY Index and All-Cause Mortality in Patients with COPD: Results from the Cohort Study of NHANES 2007–2010 by Ding Y, Liu Y, Yu J, Cai C, Fu L, Zhu J, Yang S, Jiang Y, Wang J

“…The objective of this study is to examine the correlation between the CALLY index and all-cause mortality in COPD patients.Methods: We calculated the CALLY index using data from the National Health and Nutrition Examination Survey (NHANES) for the 2007– 2008 and 2009– 2010 cycles, extracted from the participants’ peripheral blood samples. The study utilized Kaplan-Meier curves, restricted cubic spline (RCS) curves, and Cox regression analysis to evaluate the relationship between the CALLY index and the risk of all-cause mortality in COPD patients. …”
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Can “LITE” Procedure Combined With a Short Course Antibiotic Treatment Be Effective in Treating the Chronic PJI?—A Prospective Randomized Controlled Trial by Yang Chen, Haiqi Ding, Qijin Wang, Zida Huang, Chaofan Zhang, Wenbo Li, Yansheng Lin, Yufeng Guo, Xinyu Fang, Wenming Zhang

“…Continuous variables were analyzed using the two‐sample t‐test or Mann–Whitney U test, and categorical variables were analyzed using Fisher's exact tests. Kaplan–Meier survival analysis was used to compare infection control rates. …”
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Effects of respiratory sarcopenia on the postoperative course in elderly lung cancer patient: a retrospective study by Dong Jae Han, Kwon Joong Na, Taeyoung Yun, Ji Hyeon Park, Bubse Na, Samina Park, Hyun Joo Lee, In Kyu Park, Chang Hyun Kang, Young Tae Kim

“…Baseline characteristics and postoperative outcomes were compared between groups using t-tests and chi-square tests. Kaplan–Meier curves and log-rank tests were used to compare overall and recurrence-free survival. …”
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Balloon Valvuloplasty for Congenital Aortic Stenosis: Experience at a Tertiary Center in a Developing Country by Fatme A. Charafeddine, Haytham Bou Houssein, Nadine B. Kibbi, Issam M. El-Rassi, Anas M. Tabbakh, Mohammad S. Abutaqa, Ziad F. Bulbul, Nour K. Younis, Mariam T. Arabi, Fadi F. Bitar

“…At a mean follow-up of 7 years, twenty patients (69%) had more than mild aortic regurgitation, and four patients (13%) required surgical intervention. Kaplan–Meier freedom from aortic valve reintervention was 97% at 1 year and 87% at 10 years of follow-up. …”
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Comparison of Efficacy and Safety of First-Line Treatment Options for Unresectable Stage III Non-Small Cell Lung Cancer: A Retrospective Analysis by Luqing Zhao, Zhiting Zhao, Xiaoqi Yan, Fei Wu, Ning Sun, Renhong Guo, Shaorong Yu, Xiao Hu, Jifeng Feng

“…The progression-free survival (PFS) was estimated using the Kaplan–Meier method or the Cox survival regression model and compared using the log-rank test. …”
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Factors Predicting Ventilator Dependence in Patients with Ventilator-Associated Pneumonia by Chia-Cheng Tseng, Kuo-Tung Huang, Yung-Che Chen, Chin-Chou Wang, Shih-Feng Liu, Mei-Lien Tu, Yu-Hsiu Chung, Wen-Feng Fang, Meng-Chih Lin

“…Multivariate logistic regression analysis was used to identify underlying factors such as congestive cardiac failure (P=0.009), initial high oxygenation index value (P=0.04), increased SOFA scores (P=0.01), and increased APACHE II scores (P=0.02) as independent predictors of ventilator dependence. Results from the Kaplan-Meier method indicate that initial therapy with antibiotics could increase the ventilator weaning rate (log Rank test, P<0.001). …”
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Effectiveness and safety of pembrolizumab, nivolumab, and atezolizumab as adjuvant therapy for high-risk muscle-invasive urothelial carcinoma: an indirect comparison by Wei Chen, Wei Chen, Soichiro Yoshida, Noriyoshi Miura, Shohei Fukuda, Hiroshi Fukushima, Yuma Waseda, Hajime Tanaka, Yasuhisa Fujii

“…With no direct efficacy comparisons available, we aimed to indirectly compare the efficacy and safety of pembrolizumab, nivolumab, and atezolizumab as adjuvant treatments for high-risk MIUC based on individual patient data (IPD) from clinical trials.MethodsIPD was reconstructed using the Shiny method from Kaplan–Meier curves of eligible randomized controlled trials. …”
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Efficacy and safety of super selective bronchial artery coil embolisation for haemoptysis: a single-centre retrospective observational study by Daijiro Kabata, Ayumi Shintani, Masanori Akira, Masahiko Hara, Hideo Ishikawa, Misaki Ryuge, Jun Takafuji, Mihoko Youmoto, Yukio Nagasaka, Kouji Yamamoto

“…The haemoptysis-free survival rates were estimated by the Kaplan-Meier analysis at 86.9% (95% CI 83.7% to 90.2%) at 1 year, 79.4% (74.8% to 84.3%) at 2 years and 57.6% (45.1% to 73.4%) at 3 years. …”
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A comparison of drug‐eluting stent and coronary artery bypass grafting in mildly to moderately ischemic heart failure by Kun Wang, Le Wang, Hongliang Cong, Jingxia Zhang, Yuecheng Hu, Yingyi Zhang, Rui Zhang, Wenyu Li, Wei Qi

“…Propensity score‐matching analysis was performed between the two groups. Kaplan–Meier analysis and multivariate Cox proportional hazard regression were applied to assess all‐cause mortality and individual end points. …”
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Predicting recurrence of non-muscle invasive bladder urothelial carcinoma: predictive value of the optimal cut-off value of Ki67 by Rende Peng, Yaoyu Zhang, Mingzhu Jia, Xinping Yi, Xiaoyao Yi, Shadan Li, Jiangchuan Pi, Wenjun Meng

“…Univariate and multivariate regression analysis were used to analyze the relationship between the expression of Ki67 and postoperative recurrence of NMIBUC. The Kaplan-Meier curve was used for survival analysis.Results18% is the optimal cut-off value of Ki67 for predicting postoperative recurrence of NMIBUC. …”
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Autoimmune brainstem encephalitis: Clinical associations, outcomes, and proposed diagnostic criteria by Michael Gilligan, Smathorn Thakolwiboon, Emma Orozco, Samantha Banks, Eoin P. Flanagan, Sebastian Lopez‐Chiriboga, Jan‐Mendelt Tillema, John R. Mills, Sean J. Pittock, Cristina Valencia Sanchez, Anastasia Zekeridou, Divyanshu Dubey, Andrew McKeon

“…Factors associated with poor outcome included abnormal brain MRI, bulbar symptoms, and elevated CSF IgG index. Kaplan–Meier analysis revealed faster progression to wheelchair in patients who were immunotherapy refractory and with elevated CSF IgG index. …”
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The value of inflammation-related indicators in chemotherapy efficacy and disease-free survival of triple-negative breast cancer by Jie Zhu, Jiale Cheng, Yuyuan Ma, Ying Wang, Zhonghua Zou, Wenjie Wang, Haihua Shi, You Meng

“…Survival curves were obtained by Kaplan–Meier method. Models for univariate and multivariate Cox regression analyses were performed to determine the independent risk factors. …”
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Comprehensive pan-cancer analysis reveals NTN1 as an immune infiltrate risk factor and its potential prognostic value in SKCM by Fuxiang Luan, Yuying Cui, Ruizhe Huang, Zhuojie Yang, Shishi Qiao

“…Prognostic value was evaluated through univariate Cox regression and Kaplan–Meier methods. Mutation and methylation analyses were conducted using the cBioPortal and SMART databases. …”
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Risk factors and prognosis analysis of dysphagia after occipitocervical fusion surgery: a retrospective study of 43 cases by Yufan Chen, Weihong Xu

“…Prognosis was analyzed using the Kaplan-Meier method and curvilinear regression. Results Dysphagia occurred in 17 of 43 patients (39.53%). …”
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Nomogram based on the log odds of negative lymph node/T stage can predict the prognosis of patients with colorectal cancer: a retrospective study based on SEER database and externa... by Xiaochun Chen, Yimin Li, Boyong Cai, Mengli Zheng, Zhicao Chen, Canxin Zhong, Guiquan Chen

“…The performance of the nomogram was comprehensively assessed via the time-dependent receiver operating characteristic curve, concordance index (C-index), calibration curve and decision curve analysis (DCA) comprehensively. Moreover, Kaplan-Meier curves were performed to assess the CSS of the three risk subgroups.Result LONT was a significant independent prognostic factor for CSS (LONT1 vs LONT2, HR=0.670, 95% CI 0.642 to 0.698, p&lt;0.001; LONT1 vs LONT3, HR=0.443, 95% CI 0.420 to 0.467, p&lt;0.001). …”
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Prognostic evaluation of non-muscle invasive bladder cancer with P-CRP and its nomogram by Junyun Wu, Zhixuan Deng, Xu Lei, Zhiyao Xu, Chenxi Tan, Yunqiao Tang, Xi Sheng, Ning Yang

“…The endpoint of the study was the RFS. Kaplan-Meier (KM) method and Cox regression were used for analysis to identify independent factors affecting RFS. …”
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Ly6E on tumor cells impairs anti-tumor T-cell responses: a novel mechanism of tumor-induced immune exclusion by Lan Hailin, Chen Yiting, Wu Yue, Li Lijun, Zhang Renlu, Chen Yunhan, Zhu Yanyang, Zhang Qiuyu

“…Methods TCGA database and Kaplan–Meier plotter database were used to evaluate the correlation between Ly6E expression levels and cancer patient survival. …”
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