NF-κB-Specific Suppression in Cardiomyocytes Unveils Aging-Associated Responses in Cardiac Tissue by Letícia Aparecida Lopes Morgado, Larissa Maria Zacarias Rodrigues, Daiane Cristina Floriano Silva, Bruno Durante da Silva, Maria Claudia Costa Irigoyen, Ana Paula Cremasco Takano

“…<b>Methods</b>: Young and old wild-type (WT) and transgenic male mice with cardiomyocyte-specific NF-κB suppression (3M) were used to assess cardiac function, morphology, senescence markers, lipofuscin deposition, DNA damage, and apoptosis. <b>Results</b>: Kaplan–Meier analysis revealed reduced survival in 3M mice compared to WT. …”
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Clinical Characteristics and Outcomes in Patients with Ruptured Middle Cerebral Artery Aneurysms: A Multicenter Study in Northern China by Xiuhu An, Jingliang Su, Bingxin Duan, Long Zhao, Bangyue Wang, Yan Zhao, Tianxing Li, Shuai Zhou, Xinyu Yang, Zhenbo Liu

“…Methods We included patients who were consecutively admitted for ruptured MCAAs to 12 tertiary care centers in northern China from January 2017 to December 2020. Kaplan‒Meier curves were used to compare survival in hazard strata. …”
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Evaluating H2BC9 as a potential diagnostic and prognostic biomarker in head and neck squamous cell carcinoma by Lanhua Wu, Liang Li, Mingjing Zhu, Ziyan Zhou, Xuejin Su, Yueming Jiang, Min Kang, Li Jiang

“…Prognostic value was assessed using Kaplan–Meier curves, Cox regression analysis, and a nomogram. …”
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HLA-G high-expressor 3’UTR markers are linked to gastric cancer development and survival by Christian Vaquero-Yuste, Ignacio Juarez, Marta Molina-Alejandre, Elisa María Molanes-López, Alberto Gutiérrez-Calvo, Adela López-García, Inmaculada Lasa, Remedios Gómez, Antonio Arnaiz-Villena, Jose Manuel Martín-Villa

“…Survival analysis was conducted using Kaplan–Meier curves and multivariate Cox regression models. …”
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SNORA37/CMTR1/ELAVL1 feedback loop drives gastric cancer progression via facilitating CD44 alternative splicing by Banghe Bao, Minxiu Tian, Xiaojing Wang, Chunhui Yang, Jiaying Qu, Shunchen Zhou, Yang Cheng, Qiangsong Tong, Liduan Zheng

“…Survival analysis was undertaken by using Kaplan-Meier method and log-rank test. Results SNORA37 was identified as an up-regulated snoRNA essential for tumorigenesis and aggressiveness of gastric cancer. …”
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Children with autoimmune hepatitis receiving standard-of-care therapy demonstrate long-term obesity and linear growth delay by Or Steg Saban, Shannon M. Vandriel, Syeda Aiman Fatima, Celine Bourdon, Amrita Mundh, Vicky L. Ng, Simon C. Ling, Robert H.J. Bandsma, Binita M. Kamath

“…Mixed effect models assessed the impact of time and daily steroid exposure on z-scores. Kaplan-Meier survival methods were used to estimate the cumulative incidence of new-onset growth impairments. …”
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Patient and tumor factors contributing to distant metastasis in well-differentiated thyroid cancer: a retrospective cohort study by Usman Khan, Ayham Al Afif, Abdullah Aldaihani, Colin MacKay, Matthew H. Rigby, Murali Rajaraman, Syed Ali Imran, Martin J. Bullock, S. Mark Taylor, Jonathan R. B. Trites, Robert D. Hart

“…Multivariate Cox-proportional hazards model was used to evaluate the risk of developing distant metastasis over time. Kaplan-Meier analysis was used to compare survival between the DM and NDM groups. …”
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Identification of a postoperative survival scoring index for adult liver transplantation by Shuai Wang, Xiaohong Lin, Yefu Li, Zhonghao Xie, Ming Zhang, Yicheng Liang, Chuchen Zhu, Yuqi Dong, Ping Zeng, Xiaoshun He, Weiqiang Ju, Maogen Chen

“…Area under the curve (AUC) and Kaplan–Meier’s (K–M) analysis demonstrated superiority of the new index. …”
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Worst pattern of invasion: A prognostic indicator in early-stage oral tongue cancer: A single-center cohort study by Bhargav Ram, LM Chandra Sekara Rao S, Daphne Fonseca, Sravan Kumar Ch, Johnathan Gondi, Anil Kumar Akula, Hemantkumar Nemade

“…Statistical analysis was done using chi-square, cox multivariate analysis and Kaplan-Meier survival analysis. Results: In 192 patients with a mean follow-up period of 22 months, there were 39 recurrences. out of these we had 20 patients in non-aggressive WPOI and 19 in aggressive WPOI groups. …”
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Outcomes of minimal access retroperitoneal para-aortic lymphadenectomy in patients with locally advanced cervical cancer by Claire Newton, Radha Graham, Viola Liberale, Matthew Burnell, Usha Menon, Tim Mould, Adeola Olaitan, Nicola Macdonald, Martin Widschwendter, Kostas Doufekas, Mary McCormack, Anita Mitra, Rupali Arora, Ranjit Manchanda

“…Descriptive statistics were used to analyse baseline characteristics, cox models for treatment affect after accounting for variables, and Kaplan Meier curves for survival (STATA v15).Results 191 patients had 1b3-3b cervical cancer of which 110 patients had Para-aortic lymphadenectomy. 8 (7.3%) patients stage 1b3, 82 (74.6%) stage 2b, and 20 (18.1%) stage 3b cervical cancer. …”
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Prognostic value of systemic immune-inflammation index in patients with small-cell lung cancer treated with immune checkpoint inhibitors by Yusuke Hamakawa, Ayumi Hirahara, Akiko Hayashi, Kota Ito, Hiroyuki Shinohara, Aya Shiba, Yuko Higashi, Masaharu Aga, Kazuhito Miyazaki, Yuri Taniguchi, Yuki Misumi, Yoko Agemi, Yukiko Nakamura, Tsuneo Shimokawa, Hiroaki Okamoto

“…Overall survival (OS) and progression-free survival (PFS) were compared between the groups using the Kaplan–Meier method and log-rank test. Multivariate analysis using the Cox proportional hazards model was performed to identify independent prognostic factors. …”
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Immune checkpoint inhibitor‐related type 1 diabetes incidence, risk, and survival association by Fumika Kamitani, Yuichi Nishioka, Miyuki Koizumi, Hiroki Nakajima, Yukako Kurematsu, Sadanori Okada, Shinichiro Kubo, Tomoya Myojin, Tatsuya Noda, Tomoaki Imamura, Yutaka Takahashi

“…Patients with a prior diagnosis of diabetes mellitus (OR, 1.59; 95% CI, 1.03–2.46; P = 0.04) or hypothyroidism (OR, 2.48; 95% CI, 1.39–4.43; P < 0.01) also exhibited an increased risk of ICI‐T1DM. The Kaplan–Meier analysis revealed that patients with ICI‐T1DM showed higher survival rates than those without (log‐lank test, P < 0.01). …”
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MRI动脉期强化模式预测肝内胆管细胞癌患者的预后 by 陈美成, 周小琦, 马瑞霞, 冯仕庭, 马玲

“…方法回顾性分析2018年1月至2021年12月在中山大学附属第一医院手术治疗，术后病理证实为ICC的93例患者的临床、术前增强MRI、术后病理、术后随访资料。采用Kaplan-Meier生存曲线分析比较MRI增强扫描动脉期强化模式不同的三组间的DFS和OS，Cox回归分析影响ICC术后DFS和OS的危险因素。…”
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Impact of Surgical Margin Status and Tumor Volume on Mortality After Robotic Radical Prostatectomy by Zaki Zeidan, Joshua Tran, Yeagyeong Hwang, Linda My Huynh, Mai Xuan Nguyen, Erica Huang, Whitney Zhang, Thomas Ahlering

“…The secondary outcome was the risk of 15-yr PCSM via Kaplan-Meier analysis. Key findings and limitations: The group with 40–100% PTV was older and presented with more advanced grade and stage. …”
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Nivolumab plasma concentration and clearance associated with overall survival in patients with renal cell carcinoma by Aurélien Marabelle, Laurence Albiges, Angelo Paci, Cécile Dalban, David Combarel, Sophie Broutin, Christophe Maritaz, Louis Blondel

“…The relationship between PK characteristics (including clearance at Cycle 1 (CLC1), plasma concentration at Cycle 3 and clinical outcomes was assessed in 137 patients treated in NIVOREN. Kaplan-Meier methodology was used in time-to-event analyses.Results In 137 patients, the median nivolumab CLC1 was 6 mL/hour and the median plasma concentration at Cycle 3 was 48 µg/mL. …”
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The Immunohistochemical Prognostic Value of Nuclear and Cytoplasmic Silent Information Regulator 1 Protein Expression in Saudi Patients with Breast Cancer by Bayan Alharbi, Alia Aldahlawi, Mourad Assidi, Fatemah Basingab, Kawther Zaher, Jehan Alrahimi, Sara Mokhtar, Jaudah Al-Maghrabi, Abdelbaset Buhmeida, Kaltoom Al-Sakkaf

“…In luminal A, luminal B, and TNBC, nuclear and cytoplasmic SIRT1 were highly associated (<i>p</i> < 0.001). Kaplan–Meier analysis showed reduced disease-specific survival (DSS) in H2BC with high SIRT1 nuclear expression (<i>p</i> = 0.001, log-rank). …”
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New strategies in management of severe alcoholic hepatitis by P. Ye. Tkachenko, I. I. Komkova, M. V. Mayevskaya, V. T. Ivashkin

“…The survival analysis was done using Kaplan–Meyer curve with Breslow and LogRank significance estimation.Results. …”
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Racial Disparities in Cancer Guideline-Concordant Treatment Using Surveillance, Epidemiology, and End Results Data for Patients With NSCLC by Eric Ababio Anyimadu, MS, Jacklyn M. Engelbart, MD, Jason Semprini, PhD, Amanda Kahl, MPH, Cameron Trentz, MS, John M. Buatti, MD, Thomas L. Casavant, PhD, Mary E. Charlton, PhD, Guadalupe Canahuate, PhD

“…Observed probabilities and logistic regression models adjusted for age, disease stage, and race were used to assess racial disparities in treatment and survival, with the Kaplan-Meier method evaluating survival rates. Racial/ethnic groups analyzed included non-Hispanic White, non-Hispanic Black, Asian/Pacific Islander, Hispanic, and American Indian/Alaska Native. …”
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Interrelation between hypoxic liver injury and Killip classification in ST-segment elevation myocardial infarction patients by Seong Huan Choi, Ji-Hun Jang, Dae-Young Kim, Young Ju Suh, Yong-Soo Baek, Sung-Hee Shin, Seong-Ill Woo, Dae-Hyeok Kim, Jeonggeun Moon, Jon Suh, WoongChol Kang, Sang-Don Park, Sung Woo Kwon

“…Receiver operating characteristic (ROC) analysis showed that combination of HLI and Killip classification was the most sensitive predictor of mortality (AUC 0.832, 95% CI 0.78–0.882). Kaplan–Meier curve showed that patients with HLI and Killip class (III and IV) had the lowest event-free survival regarding in-hospital mortality and major cardiovascular and cerebrovascular events.ConclusionsThe presence of HLI and Killip classification were directly related to worse prognosis in STEMI patients. …”
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Clinical significance and pro-oncogenic function of DBF4 in clear cell renal cell carcinoma by Liuyan Chen, Lvying Wu, Minying Tang, Yuanhang Cheng, Kuanyin Wang, Jianan Zhang, Wenyi Deng, Lingfeng Zhu, Jin Chen

“…This overexpression was confirmed by IHC analysis of 75 pairs of clinical ccRCC tumor and adjacent tissues. Kaplan-Meier analysis revealed that high DBF4 expression was associated with a significantly lower five-year overall survival rate. …”
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